Patents by Inventor Nao Funakoshi

Nao Funakoshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050245759
    Abstract: A process for conveniently and efficiently producing a highly pure cinnamaldehyde derivative, for example, (2E)-(3-hydroxy-4-methoxy)cinnamaldehyde, which comprises reacting a benzaldehyde derivative, such as isovanillin and the like, with acetaldehyde in the presence of an alkali, in particular preferably, dropping acetaldehyde little by little thereto in an aqueous solution at a low temperature for the reaction thereof. The cinnamaldehyde derivative thus obtained is selectively reduced to produce 3-(3-hydroxy-4-substituted (with methoxy group or the like)phenyl)propionaldehyde. Further, through a reductive alkylation reaction of the compound thus produced with an aspartame, N-[N-[3-(3-hydroxy-4-substituted (with methoxy group or the like)phenyl)propyl]-L-aspartyl]-L-phenylalanine 1-methyl ester, which is useful as a sweetener having a high sweetening potency, can be industrially and efficiently produced. The processes therefor are also provided.
    Type: Application
    Filed: June 17, 2005
    Publication date: November 3, 2005
    Applicant: AJINOMOTO CO., INC.
    Inventors: Kenichi Mori, Shinji Fujita, Nao Funakoshi, Tadashi Takemoto
  • Publication number: 20050175755
    Abstract: The present invention relates to a method of manufacturing aspartyl dipeptide ester compounds, which can be used as sweeteners, and aldehydes that can be used in the manufacturing processes.
    Type: Application
    Filed: April 14, 2005
    Publication date: August 11, 2005
    Applicant: Ajinomoto Co., Inc.
    Inventors: Kazutaka Nagashima, Yuuichi Aoki, Tadashi Takemoto, Nao Funakoshi, Eriko Ono
  • Publication number: 20050009153
    Abstract: The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted ?-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
    Type: Application
    Filed: June 28, 2004
    Publication date: January 13, 2005
    Applicant: Ajinomoto Co., Inc.
    Inventors: Masakazu Sugiyama, Kunihiko Watanabe, Nao Funakoshi, Yusuke Amino, Shigeru Kawahara, Tadashi Takemoto
  • Publication number: 20050004394
    Abstract: The present invention relates to processes of producing glutamic acid compounds, for example, monatin, which are useful as, for example, production intermediates for sweetener or pharmaceutical products.
    Type: Application
    Filed: June 22, 2004
    Publication date: January 6, 2005
    Applicant: AJINOMOTO CO. IN
    Inventors: Shigeru Kawahara, Yusuke Amino, Kenichi Mori, Nao Funakoshi, Tadashi Takemoto
  • Patent number: 6794531
    Abstract: The present invention relates to a method of manufacturing aspartyl dipeptide ester compounds, which can be used as sweeteners, and aldehydes that can be used in the manufacturing processes.
    Type: Grant
    Filed: April 8, 2002
    Date of Patent: September 21, 2004
    Assignee: Ajinomoto Co., Inc.
    Inventors: Kazutaka Nagashima, Yuuichi Aoki, Tadashi Takemoto, Yusuke Amino, Nao Funakoshi, Eriko Ono
  • Publication number: 20040176472
    Abstract: The present invention relates to a method of manufacturing aspartyl dipeptide ester compounds, which can be used as sweeteners, and aldehydes that can be used in the manufacturing processes.
    Type: Application
    Filed: March 10, 2004
    Publication date: September 9, 2004
    Applicant: Ajinomoto Co., Inc.
    Inventors: Kazutaka Nagashima, Yuuichi Aoki, Tadashi Takemoto, Nao Funakoshi, Eriko Ono
  • Publication number: 20030163004
    Abstract: A process for conveniently and efficiently producing a highly pure cinnamaldehyde derivative, for example, (2E)-(3-hydroxy-4-methoxy)cinnamaldehyde, which comprises reacting a benzaldehyde derivative, such as isovanillin and the like, with acetaldehyde in the presence of an alkali, in particular preferably, dropping acetaldehyde little by little thereto in an aqueous solution at a low temperature for the reaction thereof. The cinnamaldehyde derivative thus obtained is selectively reduced to produce 3-(3-hydroxy-4-substituted (with methoxy group or the like)phenyl) propionaldehyde. Further, through a reductive alkylation reaction of the compound thus produced with an aspartame, N-[N-[3-(3-hydroxy-4-substituted (with methoxy group or the like)phenyl) propyl]-L-&agr;-aspartyl]-L-phenylalanine 1-methyl ester, which is useful as a sweetener having a high sweetening potency, can be industrially and efficiently produced. The processes therefor are also provided.
    Type: Application
    Filed: November 18, 2002
    Publication date: August 28, 2003
    Applicant: AJINOMOTO CO., INC.
    Inventors: Kenichi Mori, Shinji Fujita, Nao Funakoshi, Tadashi Takemoto
  • Publication number: 20020133037
    Abstract: The present invention relates to a method of manufacturing aspartyl dipeptide ester compounds, which can be used as sweeteners, and aldehydes that can be used in the manufacturing processes.
    Type: Application
    Filed: April 8, 2002
    Publication date: September 19, 2002
    Applicant: AJINOMOTO CO. INC
    Inventors: Kazutaka Nagashima, Yuuichi Aoki, Tadashi Takemoto, Yusuke Amino, Nao Funakoshi, Eriko Ono