Abstract: A device for treating tissue includes a capsule extending longitudinally from a proximal end to a distal end and including a lumen extending therein and a clip slidably received within the lumen of the capsule. The clip includes a middle prong, a first outer prong and a second outer prong. The first prong is coupled to the middle prong so that the first prong is movable relative to the middle prong between a first open configuration and a first closed configuration. The second outer prong coupled to the middle prong so that the second prong is movable relative to the middle prong between a second open configuration and a second closed configuration. The first and second outer prongs are independently movable relative to the middle prong to be moved between the first and second open configurations to the first and second open configurations and the first and second closed configurations.

Abstract: A system and method for treating tissue includes an applicator including a bushing and a control member. The control member extends through the bushing to an enlarged distal end. The system also includes clip assembly releasably coupleable to the applicator. The clip assembly includes clip arms and a yoke including a distal portion connected to the clip arms and a proximal portion. The proximal portion includes a slot configured to receive the enlarged distal end of the control member and at least one helical cut positioned at a proximal end of the slot. The helical cut is configured to rotate the enlarged distal end from a first orientation in which the enlarged distal end is offset from the slot to a second orientation in which the enlarged distal end is aligned with the slot so that when a force thereon exceeds a threshold value, the enlarged distal end passes into the slot.

Abstract: Disclosed herein are various systems and methods for facilitating control of a tool or tools. The systems can allow a user to control multiple degrees of freedom. One such system allows a user to control multiple degrees of freedom of two tools simultaneously. Another such system allows a user to control multiple degrees of freedom with a single hand. Frames and rails for supporting and/or constraining movement of a tool or tools are also described herein.

Abstract: A system for treating tissue includes a clip assembly having a pair of clip arms. Proximal ends of the clip arms engage a distal portion of a central member slidably received within a channel of a capsule to be moved between an open configuration and a closed configuration. The central member includes the distal portion and a proximal portion connected to one another via a releasable connection which releases when subject to a force exceeding a predetermined threshold level. The system also includes an applicator releasably coupled to the clip assembly. The applicator includes an outer sleeve through which a control member extends. A distal end of the control member engages a cavity of the proximal portion to move the central member relative to the capsule. A lumen of the outer sleeve is sized and shaped to slidably receive the capsule therein.

Abstract: Disclosed herein are devices and methods for introducing a plurality of instruments to a target site through a working channel. The working channel can include a surface adapted to guide one or more instruments into select positions. The working channel can be defined by a portion of a guide tube or tip that may be coupled with an endoscope.

Abstract: This disclosure provides design, material, manufacturing method, and use alternatives for medical devices. An example medical device may include a medical device for delivery of a surgical closure member. The medical device includes an elongate tubular member having a proximal end, a distal end and a lumen extending therein. The elongate tubular member is adapted to be delivered through the working channel of an endoscope and the lumen is adapted to receive a surgical closure member. The medical device also includes a tissue support extending from the distal end of the elongate tubular member. The tissue support includes a support surface and the support surface is adapted to support tissue as a surgical closure member engages the tissue thereon.

Abstract: A device for treating a tissue opening includes a capsule extending longitudinally from a proximal end to a distal end and including a lumen extending therethrough; a pair of arms movably housed within the lumen of the capsule such that the pair of arms are movable between an open configuration and a closed configuration, the pair of arms being biased toward the open configuration such that when the pair of arms are moved distally with respect to the capsule, distal ends of the pair of arms are separated from one another to receive target tissue therebetween; a needle releasably connected to a first one of the pair of arms, the needle extending laterally inward toward a second one of the pair of arms and including a connecting structure extending along a portion thereof, the second one of the pair of arms including an opening located so that, when the pair of arms are moved to the closed configuration, the connecting structure of the needle engages the opening; and a suture extending from a portion of the nee

Abstract: A device for treating a tissue opening includes a proximal portion including an elongated flexible member, a capsule releasably coupled to a distal end of the flexible member and including a lumen extending therethrough and a clip including a pair of arms movably housed within the capsule. A suture extending along a first one of the pair of arms and including a loop at a distal end thereof extending across an opening extending through the first one of the pair of arms. A suture grabbing element extending laterally from a second one of the pair of arms and including a hook so that, when the pair of arms are moved toward a closed configuration, the hook extends through the opening to grab the loop and draw the distal end of the suture from the first one of the pair of arms toward the second one of the pair of arms.

Abstract: Embodiments of the disclosure may include a medical device comprising a flexible elongate member including a longitudinal axis and a tool connected to the elongate member near a pivot, wherein the tool may be configured for at least one of suction and infusion, and wherein the tool may be configured to pivot towards both sides of the longitudinal axis relative to the elongate member at the pivot.

Abstract: Exemplary medical devices may include a snare device. The snare device may include a first leg having a proximalmost end and a second leg having a proximalmost end. The first leg and the second leg may form a distal loop. The proximalmost end of first leg may be independently moveable relative to the proximalmost end of the second leg.

Abstract: A device for treating tissue includes a capsule extending longitudinally from a proximal end to a distal end and including a channel extending therethrough, the capsule releasably coupled to a proximal portion of the device and clip jaws, proximal ends of which are slidably received within the channel of the capsule so that the clip jaws are movable between an open configuration and a closed configuration. Clip jaws are configured so that a distance between the distal ends of the clip jaws in an open configuration is between 15 and 18 millimeters. Clip jaws further include barbs extending from a distal portion thereof.

Abstract: This invention is directed to a medical device having a longitudinal axis, and including a handle and a catheter. The handle can include a body having a proximal end and a distal end, an actuator moveably coupled to the body, and a handle control member coupled to the actuator, wherein the actuator can be configured to move relative to the body to move the handle control member. The catheter can include a shaft having a proximal end and a distal end, wherein the proximal end of the shaft and the distal end of the body can be configured for releasable coupling. The catheter can also include a steering section located along the shaft and a catheter control member coupled to the steering section, wherein the catheter control member can be configured to move relative to the shaft to move the steering section relative to the longitudinal axis.

Abstract: A system for treating tissue includes an applicator having a bushing and a control member and a clip assembly having a capsule with a channel extending therethrough. The channel includes proximal and distal portions. The distal portion extends distally from the proximal portion and flaring outward in a single plane to form opposing flared sections. The assembly also includes clip arms include proximal ends slidably received within the channel to move the arms between tissue receiving and tissue clipping configurations. The assembly further includes a yoke including a distal portion connected to the arms and a proximal portion configured to be connected to the member so that longitudinal movement of the member relative to the capsule moves the arms between the tissue receiving and clipping configurations. The yoke is positioned in the capsule so that the yoke is deformable in the plane in which the capsule flares outward.

Abstract: A device for treating a tissue opening includes a proximal portion including an elongated flexible member, a capsule releasably coupled to a distal end of the flexible member and including a lumen extending therethrough and a clip including a pair of arms movably housed within the capsule. A suture extending along a first one of the pair of arms and including a loop at a distal end thereof extending across an opening extending through the first one of the pair of arms. A suture grabbing element extending laterally from a second one of the pair of arms and including a hook so that, when the pair of arms are moved toward a closed configuration, the hook extends through the opening to grab the loop and draw the distal end of the suture from the first one of the pair of arms toward the second one of the pair of arms.

Abstract: A device includes a capsule extending longitudinally from a proximal end to a distal end and including a channel extending therethrough. The capsule is releasably coupled to a proximal portion of the device. Device also includes a first arm rigidly fixed to the distal end of the capsule to extend distally therefrom. In addition, Device includes a second arm, a proximal end of which is slidably received within the capsule so that the second arm is movable between an open configuration, in which the second arm is moved laterally away from the first arm and a distal end of the second arm is moved distally past the distal end of the first arm, and a closed configuration, in which the second arm is moved toward the first arm and the distal end of the second arm is moved proximally toward the distal end of the first arm.

Abstract: Exemplary medical devices may include a snare device. The snare device may include a first leg having a proximalmost end and a second leg having a proximalmost end. The first leg and the second leg may form a distal loop. The proximalmost end of first leg may be independently moveable relative to the proximalmost end of the second leg.

Abstract: A device for treating tissue includes a capsule extending longitudinally from a proximal end to a distal end and including a channel extending therethrough, the capsule releasably coupled to a proximal portion of the device and clip jaws, proximal ends of which are slidably received within the channel of the capsule so that the clip jaws are movable between an open configuration and a closed configuration. Clip jaws are configured so that a distance between the distal ends of the clip jaws in an open configuration is between 15 and 18 millimeters. Clip jaws further include barbs extending from a distal portion thereof.

Abstract: This invention is directed to a medical device having a longitudinal axis, and including a handle and a catheter. The handle can include a body having a proximal end and a distal end, an actuator moveably coupled to the body, and a handle control member coupled to the actuator, wherein the actuator can be configured to move relative to the body to move the handle control member. The catheter can include a shaft having a proximal end and a distal end, wherein the proximal end of the shaft and the distal end of the body can be configured for releasable coupling. The catheter can also include a steering section located along the shaft and a catheter control member coupled to the steering section, wherein the catheter control member can be configured to move relative to the shaft to move the steering section relative to the longitudinal axis.

Abstract: A system for treating tissue includes an applicator having a bushing and a control member and a clip assembly having a capsule with a channel extending therethrough. The channel includes proximal and distal portions. The distal portion extends distally from the proximal portion and flaring outward in a single plane to form opposing flared sections. The assembly also includes clip arms include proximal ends slidably received within the channel to move the arms between tissue receiving and tissue clipping configurations. The assembly further includes a yoke including a distal portion connected to the arms and a proximal portion configured to be connected to the member so that longitudinal movement of the member relative to the capsule moves the arms between the tissue receiving and clipping configurations. The yoke is positioned in the capsule so that the yoke is deformable in the plane in which the capsule flares outward.

Abstract: A device includes a capsule extending longitudinally from a proximal end to a distal end and including a channel extending therethrough. The capsule is releasably coupled to a proximal portion of the device. Device also includes a first arm rigidly fixed to the distal end of the capsule to extend distally therefrom. In addition, Device includes a second arm, a proximal end of which is slidably received within the capsule so that the second arm is movable between an open configuration, in which the second arm is moved laterally away from the first arm and a distal end of the second arm is moved distally past the distal end of the first arm, and a closed configuration, in which the second arm is moved toward the first arm and the distal end of the second arm is moved proximally toward the distal end of the first arm.