Abstract: A medical device for manipulating a tissue is disclosed. The device includes an elongate shaft having a proximal end, a distal end, and a first lumen between the proximal end and the distal end, which has an opening in communication with the first lumen. The elongate shaft further includes a second lumen or aperture disposed in an external surface of the elongate shaft. The device further includes: a support truss, a snare loop, and an actuation member having a distal end. The actuation member is movably disposed within the first lumen. The support truss is configured to be received within the first lumen, second lumen, or aperture such that a proximal end of the support truss is operably connected to the elongate shaft adjacent a proximal portion of the first lumen, second lumen, or aperture. The snare loop has a first portion connected to a distal end of the support truss and a second portion connected to the distal end of the actuation member.

Abstract: Disclosed herein are devices and methods for introducing a plurality of instruments to a target site through a working channel. The working channel can include a surface adapted to guide one or more instruments into select positions. The working channel can be defined by a portion of a guide tube or tip that may be coupled with an endoscope.

Abstract: A medical/surgical device for performing tissue resection can include an endoscope with proximal and distal ends, defining working channels, and a snare assembly located in one of the working channels. The working channel may include a bend near the distal end and towards the outward radial wall of the endoscope. The snare assembly may include a snare loop and an actuation element imparted with the pre-formed angular bends and an actuation control handle. The bends of the actuation element and the working channel may be the same. The rotational manipulation of the actuation element may synchronize the pre-formed bend of the actuation element with the bend of the working channel to concentrically (or otherwise) align the deployed snare loop with the endoscope or endoscope attachments.

Abstract: Disclosed herein are devices and methods for introducing a plurality of instruments to a target site through a working channel. The working channel can include a surface adapted to guide one or more instruments into select positions. The working channel can be defined by a portion of a guide tube or tip that may be coupled with an endoscope.

Abstract: A medical device may include tubular member having a proximal end, a distal end, and a lumen extending therebetween. The tubular member may include an opening at a distal portion of the tubular member, wherein the opening is in communication with the lumen, wherein a distal end of the opening is disposed proximate of the distal end of the tubular member, and wherein the distal portion of the tubular member is configured to bend in at least one plane. The medical device may further include an actuation member extending at least partially within the tubular member, wherein a distal portion of the actuation member is configured to exit the tubular member at a location proximate the opening, wherein a distal end of the actuation member is coupled to the distal end of the tubular member, and wherein pulling the actuation member proximally is configured to cause the distal portion of tubular member to form a loop with itself.

Abstract: A medical device for resecting tissue. The medical device includes a catheter shaft having a proximal portion and two or more distal branch portions. The distal branch portions are moveable between a closed position, and an open position. One or more lumens extend between the proximal portion and through each distal branch portion. An actuation element extends through the lumen of each distal branch portion. A snare loop is connected to each actuation element.

Abstract: A device for tissue resection and methods of using the same is disclosed, including a snare loop and a tubular handle. The snare loop has both conductive and insulated portions such that the snare loop can be used to cut tissue selectively to make perimeter cuts on the tissue to be resected. The snare loop may be placed and tightened on a target tissue and may be activated for cutting the tissue to be resected by passing an electrical current through the snare loop. Some embodiments of the device include a hood and cutting wire for making perimeter cuts on the tissue to be resected.

Abstract: A medical device may include a housing. The housing may include an outer wall, an inner wall spaced from the outer wall, and a cavity between the outer wall and the inner wall. The cavity may be in fluid communication with a lumen configured to adjust pressure within the cavity. The medical device may also include a cutting tool configured to move from extending around an outer surface of the housing to entering the cavity of the housing.

Abstract: A tissue resection device for resecting tissue from a target site within a patient's body. The device includes an elongate shaft having a proximal end and a distal end. An actuation member extends partially through the shaft, and reciprocates within the shaft between a retracted position and an extended position. Multiple snare wires extend through the actuation member, and emerge outwards from a distal portion of the actuation member. The snare wires cooperate and join to form a snare loop, which engages the tissue intended to be resected. The snare loop is configured to enhance friction while engaging the tissue, to resect the tissue.

Abstract: The present disclosure is directed to a medical instrument. The medical instrument may include a shaft having a distal end configured to cauterize tissue. An expandable member may be positioned adjacent the distal end of the shaft. The expandable member may be configured for deployment between a collapsed configuration and an expanded configuration.

Abstract: A medical device may include an elongate member including a proximal end and a distal end. The medical device may also include a rotatable member at the distal end of the elongate member. The rotatable member may be rotatably coupled to the distal end of the elongate member. The rotatable member may include a longitudinal axis, and may be configured to rotate about the longitudinal axis. The rotatable member may also include a gripping element configured to engage a layer of tissue. The gripping element may be configured to selectively couple at least a portion of the layer of tissue to a surface of the rotatable member, to restrict relative movement between the portion of the layer of tissue and the surface of the rotatable member, during rotation of the rotatable member.

Abstract: Embodiments of the present disclosure include a method for treating tissue. The method may include delivering a medical device through a channel of an endoscopic device, wherein the medical device may include an elongate member, a cap coupled to a distal end of the elongate member and having a cavity, and an electrically-conductive tool extending into the cavity of the cap. The method may also include extending a portion of the medical device out of the channel of the endoscopic device and to the tissue, drawing a portion of the tissue into the cavity of the cap, electrically activating the tool to pierce the portion of the tissue, and cutting the tissue by moving the medical device along a plane of the tissue.

Abstract: A medical device may include a housing. The housing may include an outer wall, an inner wall spaced from the outer wall, and a cavity defined by the outer wall and the inner wall. The distal end of the outer wall may be disposed proximally from the distal end of the inner wall. The housing may further define a passageway therethrough. The cavity may be in fluid communication with a port configured to adjust pressure within the cavity.

Abstract: A tissue resection hood and related method of use for resecting the tissue are described. The tissue resection hood may include a distal end portion having an opening, a proximal end portion, and a cavity defined between the proximal and distal end portions, wherein the proximal end portion defines an opening configured to couple to an end of a sheath. The tissue resection hood may further include a cutting member configured to traverse the opening in the distal end portion and a mechanism configured to control a dimension of the cavity.

Abstract: This invention is directed to a medical device having a longitudinal axis, and including a handle and a catheter. The handle can include a body having a proximal end and a distal end, an actuator moveably coupled to the body, and a handle control member coupled to the actuator, wherein the actuator can be configured to move relative to the body to move the handle control member. The catheter can include a shaft having a proximal end and a distal end, wherein the proximal end of the shaft and the distal end of the body can be configured for releasable coupling. The catheter can also include a steering section located along the shaft and a catheter control member coupled to the steering section, wherein the catheter control member can be configured to move relative to the shaft to move the steering section relative to the longitudinal axis.

Abstract: A medical system including an endoscope having a proximal end, a distal end, and a lumen extending therebetween is disclosed. The endoscope includes a port configured to provide access to the lumen. In addition, the system may include an actuation member slidably disposed through the lumen such that a proximal end of the actuation member extends through the port, and a distal end of the actuation member is operably coupled to an end-effector. The system may further include an actuation handle removably secured to the actuation member. In one embodiment, a portion of the end-effector has dimensions larger than a maximum dimension of the lumen.

Abstract: Medical systems are disclosed and may include an elongate member having a proximal end, a distal end, one or more channels extending between the proximal end and the distal end, and a handle operably coupled to the proximal end. The handle may include one or more ports in communication with the one or more channels. The medical systems may further include a docking station supporting the proximal end of the elongate member. The docking station may include a receiver adapted to receive and secure the handle and an adaptor guide unit having a distal end, a proximal end, and one or more passages formed therethrough, the one or more passages communicating with the one or more channels.

Abstract: Embodiments of the present disclosure include a medical device. The medical device may include a proximal handle, a distal tool, an elongate member connecting the distal tool to the proximal handle and including a first portion and a second portion, wherein the elongate member may be configured to deliver electrical energy to the distal tool, and a coupling mechanism configured to connect and disconnect the first and second portions of the elongate member.

Abstract: This invention is directed to a medical device with a handle and a catheter. The handle can include a body having a proximal end and a distal end, an actuator moveably coupled to the body, and a handle control member coupled to the actuator, wherein the actuator can be configured to move relative to the body to move the handle control member. The catheter can include a shaft having a proximal end and a distal end, wherein the proximal end of the shaft and the distal end of the body can be configured for releasable coupling. The catheter can also include a steering section located along the shaft and a catheter control member coupled to the steering section. A securing member may move relative to at least one of the handle and the catheter to releasably couple the handle control member to the catheter control member.

Abstract: A device configured to facilitate resection of tissue. The device may include a proximal end configured to be secured to a distal portion of an introduction sheath and a distal end defining an opening that may communicate with a channel extending between the proximal and distal ends. The opening may be defined by at least one straight edge.