Patents by Inventor Nathalie Marie-Josephe Garcon

Nathalie Marie-Josephe Garcon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PNEUMOCOCCAL CAPSULAR SACCHARIDE CONJUGATE VACCINE
    Publication number: 20220354941
    Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, an immunogenic composition for infants is provided comprising a multivalent Streptococcus pneumoniae vaccine comprising 2 or more capsular saccharide conjugates from different serotypes, wherein the composition comprises a serotype 22F saccharide conjugate. Such a vaccine may be used in infant populations to reduce the incidence of elderly pneumococcal disease such as exacerbations of COPD and/or IPD.
    Type: Application
    Filed: June 30, 2022
    Publication date: November 10, 2022
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Ralph Leon BIEMANS, Nathalie Marie-Josephe GARCON, Philippe Vincent HERMAND, Jan POOLMAN, Marcelle Paulette VAN MECHELEN
  • Pneumococcal capsular saccharide conjugate vaccine
    Patent number: 11400147
    Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, an immunogenic composition for infants is provided comprising a multivalent Streptococcus pneumoniae vaccine comprising 2 or more capsular saccharide conjugates from different serotypes, wherein the composition comprises a serotype 22F saccharide conjugate. Such a vaccine may be used in infant populations to reduce the incidence of elderly pneumococcal disease such as exacerbations of COPD and/or IPD.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: August 2, 2022
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Ralph Leon Biemans, Nathalie Marie-Josephe Garcon, Philippe Vincent Hermand, Jan Poolman, Marcelle Paulette Van Mechelen
  • Vaccine
    Patent number: 10646564
    Abstract: The present invention discloses an immunogenic composition comprising S. pneumoniae capsular saccharide conjugates from serotypes 19A and 19F wherein 19A is conjugated to a first bacterial toxoid and 19F is conjugated to a second bacterial toxoid. Vaccines, methods of making vaccines and uses of the vaccines are also described.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: May 12, 2020
    Assignee: GlaxoSmithKline Biologicals S.A.
    Inventors: Ralph Leon Biemans, Nathalie Marie-Josephe Garcon, Philippe Vincent Hermand, Jan Poolman, Marcelle Paulette Van Mechelen
  • Vaccine
    Publication number: 20190262447
    Abstract: The present invention discloses an immunogenic composition comprising S. pneumoniae capsular saccharide conjugates from serotypes 19A and 19F wherein 19A is conjugated to a first bacterial toxoid and 19F is conjugated to a second bacterial toxoid. Vaccines, methods of making vaccines and uses of the vaccines are also described.
    Type: Application
    Filed: February 21, 2019
    Publication date: August 29, 2019
    Inventors: Ralph Leon Biemans, Nathalie Marie-Josephe Garcon, Philippe Vincent Hermand, Jan Poolman, Marcelle Paulette Van Mechelen
  • Vaccine comprising capsular polysaccharide conjugates
    Patent number: 10279033
    Abstract: The present invention discloses an immunogenic composition comprising S. pneumoniae capsular saccharide conjugates from serotypes 19A and 19F wherein 19A is conjugated to a first bacterial toxoid and 19F is conjugated to a second bacterial toxoid. Vaccines, methods of making vaccines and uses of the vaccines are also described.
    Type: Grant
    Filed: January 5, 2016
    Date of Patent: May 7, 2019
    Assignee: GlaxoSmithKline Biologicals SA
    Inventors: Ralph Leon Biemans, Nathalie Marie-Josephe Garcon, Philippe Vincent Hermand, Jan Poolman, Marcelle Paulette Van Mechelen
  • VACCINE COMPRISING STREPTOCOCCUS PNEUMONIAE CAPSULAR POLYSACCHARIDE CONJUGATES
    Publication number: 20180250389
    Abstract: The present invention discloses an immunogenic composition comprising S. pneumoniae capsular saccharide conjugates from serotypes 19A and 19F wherein 19A is conjugated to a first bacterial toxoid and 19F is conjugated to a second bacterial toxoid. Vaccines, methods of making vaccines and uses of the vaccines are also described.
    Type: Application
    Filed: January 5, 2016
    Publication date: September 6, 2018
    Inventors: Ralph Leon BIEMANS, Nathalie Marie-Josephe GARCON, Philippe Vincent HERMAND, Jan POOLMAN, Marcelle Paulette VAN MECHELEN
  • PNEUMOCOCCAL CAPSULAR SACCHARIDE CONJUGATE VACCINE
    Publication number: 20180207262
    Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, an immunogenic composition for infants is provided comprising a multivalent Streptococcus pneumoniae vaccine comprising 2 or more capsular saccharide conjugates from different serotypes, wherein the composition comprises a serotype 22F saccharide conjugate. Such a vaccine may be used in infant populations to reduce the incidence of elderly pneumococcal disease such as exacerbations of COPD and/or IPD.
    Type: Application
    Filed: January 12, 2018
    Publication date: July 26, 2018
    Inventors: Ralph Leon BIEMANS, Nathalie Marie-Josephe GARCON, Philippe Vincent HERMAND, Jan POOLMAN, Marcelle Paulette VAN MECHELEN
  • Pneumoccal polysacchride conjugate vaccine
    Patent number: 9884113
    Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, a multivalent Streptococcus pneumoniae immunogenic composition is provided with various conjugated capsular saccharides from different S. pneumoniae serotypes conjugated to 2 or more different carrier proteins, where the composition comprises serotype 19F capsular saccharide conjugated to diphtheria toxoid (DT) or CRM197, optionally wherein 19F is the only saccharide in the composition conjugated to diphtheria toxoid (DT) or CRM197.
    Type: Grant
    Filed: June 3, 2015
    Date of Patent: February 6, 2018
    Assignee: GlaxoSmithKline Biologicals, SA
    Inventors: Ralph Leon Biemans, Nathalie Marie-Josephe Garcon, Philippe Vincent Hermand, Jan Poolman, Marcelle Paulette Van Mechelen
  • Vaccine comprising capsular polysaccharide conjugates
    Patent number: 9610339
    Abstract: The present invention relates to an immunogenic composition comprising S. pneumoniae capsular saccharide conjugates from serotypes 19A and 19F wherein 19A is conjugated to a first bacterial toxoid and 19F is conjugated to a second bacterial toxoid. Methods of making and uses thereof are also described.
    Type: Grant
    Filed: June 24, 2008
    Date of Patent: April 4, 2017
    Assignee: GlaxoSmithKline Biologicals, S.A.
    Inventors: Ralph Leon Biemans, Nathalie Marie-Josephe Garçon, Philippe Vincent Hermand, Jan Poolman, Marcelle Paulette Van Mechelen
  • Vaccine comprising capsular polysaccharide conjugates
    Patent number: 9610340
    Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, a multivalent Streptococcus pneumoniae immunogenic composition is provided with various conjugated capsular saccharides from different S. pneumoniae serotypes conjugated to 2 or more different carrier proteins, where the composition comprises serotype 19F capsular saccharide conjugated to diphtheria toxoid (DT) or CRM197, optionally wherein 19F is the only saccharide in the composition conjugated to diphtheria toxoid (DT) or CRM197.
    Type: Grant
    Filed: June 24, 2008
    Date of Patent: April 4, 2017
    Assignee: GlaxoSmithKline Biologicals, S.A.
    Inventors: Ralph Leon Biemans, Nathalie Marie-Josephe Garçon, Philippe Vincent Hermand, Jan Poolman, Marcelle Paulette Van Mechelen
  • VACCINE COMPRISING STREPTOCOCCUS PNEUMONIAE CAPSULAR POLYSACCHARIDE CONJUGATES
    Publication number: 20160243219
    Abstract: The present invention discloses an immunogenic composition comprising S. pneumoniae capsular saccharide conjugates from serotypes 19A and 19F wherein 19A is conjugated to a first bacterial toxoid and 19F is conjugated to a second bacterial toxoid. Vaccines, methods of making vaccines and uses of the vaccines are also described.
    Type: Application
    Filed: January 5, 2016
    Publication date: August 25, 2016
    Inventors: Ralph Leon BIEMANS, Nathalie Marie-Josephe GARCON, Philippe Vincent HERMAND, Jan POOLMAN, Marcelle Paulette VAN MECHELEN
  • Polyanionic polymer adjuvants for Haemophilus influenzae B saccharide vaccines
    Patent number: 9364533
    Abstract: The present invention relates to methods of reducing flocculation in an immunogenic composition, where said immunogenic composition comprises (a) Haemophilus influenzae B capsular polysaccharide or oligosaccharide (PRP) and (b) at least one non-PRP antigen. The invention further relates to kits comprising (i) a first composition comprising a Haemophilus influenzae B capsular polysaccharide or oligosaccharide (PRP) and a polyanionic polymer, and (ii) a second composition comprising a non-PRP antigen adsorbed onto an adjuvant with a zero point charge greater than 8.
    Type: Grant
    Filed: October 8, 2014
    Date of Patent: June 14, 2016
    Assignee: GLAXOSMITHKLINE BIOLOGICALS S.A.
    Inventors: Nathalie Marie-Josephe Garcon, Dominique Lemoine, Florence Emilie Jeanne Francoise Wauters
  • PNEUMOCCAL POLYSACCHRIDE CONJUGATE VACCINE
    Publication number: 20150265702
    Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, a multivalent Streptococcus pneumoniae immunogenic composition is provided with various conjugated capsular saccharides from different S. pneumoniae serotypes conjugated to 2 or more different carrier proteins, where the composition comprises serotype 19F capsular saccharide conjugated to diphtheria toxoid (DT) or CRM197, optionally wherein 19F is the only saccharide in the composition conjugated to diphtheria toxoid (DT) or CRM197.
    Type: Application
    Filed: June 3, 2015
    Publication date: September 24, 2015
    Inventors: Ralph Leon BIEMANS, Nathalie Marie-Josephe GARCON, Philippe Vincent HERMAND, Jan POOLMAN, Marcelle Paulette VAN MECHELEN
  • Pneumococcal polysaccharide conjugate vaccine
    Patent number: 9107872
    Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, a multivalent Streptococcus pneumoniae immunogenic composition is provided with various conjugated capsular saccharides from different S. pneumoniae serotypes conjugated to 2 or more different carrier proteins, where the composition comprises serotype 19F capsular saccharide conjugated to diphtheria toxoid (DT) or CRM197, optionally wherein 19F is the only saccharide in the composition conjugated to diphtheria toxoid (DT) or CRM197.
    Type: Grant
    Filed: September 30, 2009
    Date of Patent: August 18, 2015
    Assignee: GlaxoSmithKline Biologicals S.A.
    Inventors: Ralph Leon Biemans, Nathalie Marie-Josephe Garcon, Philippe Vincent Hermand, Jan Poolman, Marcelle Paulette Van Mechelen
  • Pneumococcal capsular saccharide conjugate vaccine
    Publication number: 20150190521
    Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, an immunogenic composition for infants is provided comprising a multivalent Streptococcus pneumoniae vaccine comprising 2 or more capsular saccharide conjugates from different serotypes, wherein the composition comprises a serotype 22F saccharide conjugate. Such a vaccine may be used in infant populations to reduce the incidence of elderly pneumococcal disease such as exacerbations of COPD and/or IPD.
    Type: Application
    Filed: August 14, 2014
    Publication date: July 9, 2015
    Inventors: Ralph Leon BIEMANS, Nathalie Marie-Josephe GARCON, Philippe Vincent HERMAND, Jan POOLMAN, Marcelle Paulette VAN MECHELEN
  • POLYANIONIC POLYMER ADJUVANTS FOR HAEMOPHILUS INFLUENZAE B SACCHARIDE VACCINES
    Publication number: 20150037368
    Abstract: The present invention relates to methods of reducing flocculation in an immunogenic composition, where said immunogenic composition comprises (a) Haemophilus influenzae B capsular polysaccharide or oligosaccharide (PRP) and (b) at least one non-PRP antigen. The invention further relates to kits comprising (i) a first composition comprising a Haemophilus influenzae B capsular polysaccharide or oligosaccharide (PRP) and a polyanionic polymer, and (ii) a second composition comprising a non-PRP antigen adsorbed onto an adjuvant with a zero point charge greater than 8.
    Type: Application
    Filed: October 8, 2014
    Publication date: February 5, 2015
    Inventors: Nathalie Marie-Josephe GARCON, Dominique LEMOINE, Florence Emilie Jeanne Francoise WAUTERS
  • VACCINE COMPRISING A TLR-5 AGONIST AS ADJUVANT FOR USE IN CUTANEOUS IMMUNISATION
    Publication number: 20140322271
    Abstract: The present invention provides immunogenic compositions comprising one or more antigens and an adjuvant for use in cutaneous immunisation wherein said adjuvant is a TLR-5 agonist.
    Type: Application
    Filed: November 19, 2012
    Publication date: October 30, 2014
    Inventors: Nathalie Marie-Josephe Garcon-Johnson, Marcelle Paulette Van Mechelen, Martin Plante
  • VACCINE
    Publication number: 20140322272
    Abstract: The present invention provides immunogenic compositions comprising one or more antigens and an adjuvant for use in cutaneous immunisation wherein said adjuvant is an immunologically active saponin.
    Type: Application
    Filed: November 19, 2012
    Publication date: October 30, 2014
    Inventors: Nathalie Marie-Josephe Garcon-Johnson, Marcelle Paulette Van Mechelen, Martin Plante
  • POLYANIONIC POLYMER ADJUVANTS FOR HAEMOPHILUS INFLUENZAE B SACCHARIDE VACCINES
    Publication number: 20130337006
    Abstract: The present invention relates to immunogenic compositions comprising capsular polysaccharide or oligosaccharide of H. influenzae B (PRP) and methods of making such compositions.
    Type: Application
    Filed: June 17, 2013
    Publication date: December 19, 2013
    Inventors: Nathalie Marie-Josephe GARCON, Dominique Lemoine, Florence Emilie Jeanne Francoise Wauters
  • POLYANIONIC POLYMER ADJUVANTS FOR HAEMOPHILUS INFLUENZAE B SACCHARIDE VACCINES
    Publication number: 20120195937
    Abstract: The present invention relates to immunogenic compositions comprising capsular polysaccharide or oligosaccharide of H. influenzae B (PRP) and methods of making such compositions.
    Type: Application
    Filed: February 15, 2012
    Publication date: August 2, 2012
    Inventors: Nathalie Marie-Josephe GARCON, Dominique Lemoine, Florence Emilie Jeanne Francoise Wauters