Patents by Inventor Nathalie Marie-Josephe Garcon

Nathalie Marie-Josephe Garcon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polyanionic polymer adjuvants for B saccharide vaccines
    Patent number: 8137681
    Abstract: The present invention relates to the field of vaccines, and in particular vaccines comprising antigens of low isoelectric point at pH 7.0, in particular the capsular polysaccharide or oligosaccharide of H. influenzae B (PRP). Immunogenic compositions and methods of making such compositions are presented in which the PRP is surprisingly protected from immune interference by adding a polyanionic polymer (such as PLG—poly-L-glutamic acid) to the composition.
    Type: Grant
    Filed: May 24, 2010
    Date of Patent: March 20, 2012
    Assignee: Glaxosmithkline Biologicals, S.A.
    Inventors: Nathalie Marie-Josephe Garcon, Dominique Lemoine, Florence Emilie Jeanne Francoise Wauters
  • Polyanionic polymer adjuvants for haemophilus influenzae B saccharide vaccines
    Patent number: 8007818
    Abstract: The present invention relates to the field of vaccines, and in particular vaccines comprising antigens of low isoelectric point at pH 7.0, in particular the capsular polysaccharide or oligosaccharide of H. influenzae B (PRP). Immunogenic compositions and methods of making such compositions are presented in which the PRP is surprisingly protected from immune interference by adding a polyanionic polymer (such as PLG-poly-L-glutamic acid) to the composition.
    Type: Grant
    Filed: June 14, 2004
    Date of Patent: August 30, 2011
    Assignee: GlaxoSmithKline Biologicals, S.R.
    Inventors: Nathalie Marie-Josephe Garcon, Dominique Lemoine, Florence Emilie Jeanne Francoise Wauters
  • VACCINES
    Publication number: 20100266672
    Abstract: The present invention provides a vaccine composition comprising the B subunit of Shiga toxin or an immunologically functional equivalent thereof which is able to bind the Gb3 receptor, complexed with at least one first antigen, and further comprising at least one second antigen (which may be the same or different as the first antigen) and an adjuvant.
    Type: Application
    Filed: November 28, 2006
    Publication date: October 21, 2010
    Inventors: Nathalie Marie-Josephe Garcon, Emmanuel Jules Hanon
  • VACCINE COMPOSITION
    Publication number: 20100233201
    Abstract: The present invention relates to the field of vaccines, and in particular vaccines comprising antigens of low isoelectric point at pH 7.0, in particular the capsular polysaccharide or oligosaccharide of H. influenzae B (PRP). Immunogenic compositions and methods of making such compositions are presented in which the PRP is surprisingly protected from immune interference by adding a polyanionic polymer (such as PLG—poly-L-glutamic acid) to the composition.
    Type: Application
    Filed: May 24, 2010
    Publication date: September 16, 2010
    Inventors: NATHALIE MARIE-JOSEPHE GARCON, Dominique Lemoine, Florence Emilie Jeanne Francoise Wauters
  • Vaccines Containing Non-Live Antigenic Vectors
    Publication number: 20100196451
    Abstract: The present invention provides a vaccine composition comprising a non-live vector which targets the MHC class I pathway derived from a bacterial toxin or an immunologically functional derivative thereof but excluding those which bind the Gb3 receptor complexed with at least one first antigen and further comprising at least one second antigen (which may be the same or different as the first antigen) and an adjuvant.
    Type: Application
    Filed: November 28, 2006
    Publication date: August 5, 2010
    Inventors: Nathalie Marie-Josephe Garcon, Emmanuel Jules Hanon
  • Pneumococcal polysaccharide conjugate vaccine
    Publication number: 20100074922
    Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, a multivalent Streptococcus pneumoniae immunogenic composition is provided with various conjugated capsular saccharides from different S. pneumoniae serotypes conjugated to 2 or more different carrier proteins, where the composition comprises serotype 19F capsular saccharide conjugated to diphtheria toxoid (DT) or CRM197, optionally wherein 19F is the only saccharide in the composition conjugated to diphtheria toxoid (DT) or CRM197.
    Type: Application
    Filed: September 30, 2009
    Publication date: March 25, 2010
    Inventors: Ralph Leon Biemans, Nathalie Marie-Josephe Garcon, Philippe Vincent Hermand, Jan Poolman, Marcelle Paulette Van Mechelen
  • Vaccine Compositions Comprising Virosomes and a Saponin Adjuvant
    Publication number: 20090263470
    Abstract: This invention provides virosome preparations from an enveloped virus, in particular from influenza virus, containing from said virus, and a saponin adjuvant. In particular the invention provides a virosome preparation from influenza virus an influenza antigen a QS21, optionally with a sterol. The invention also provides vaccine compositions containing said virosome preparations, methods of preparing said virosome preparations and vaccine containing them.
    Type: Application
    Filed: May 26, 2005
    Publication date: October 22, 2009
    Inventors: Beth-Ann Coller, Veronique Henderickx, Nathalie Marie-Josephe Garcon
  • Vaccines
    Patent number: 7510698
    Abstract: The present invention provides vaccine compositions comprising an oil-in-water emulsion optionally with 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccine compositions are potent induces of a range of immune responses.
    Type: Grant
    Filed: January 12, 2007
    Date of Patent: March 31, 2009
    Assignee: GlaxoSmithKline Biologicals SA
    Inventors: Patricia Marie Momin, Nathalie Marie-Josephe Garcon
  • Vaccine Comprising Streptococcus Pneumoniae Capsular Polysaccharide Conjugates
    Publication number: 20090017059
    Abstract: The present invention discloses an immunogenic composition comprising S. pneumoniae capsular saccharide conjugates from serotypes 19A and 19F wherein 19A is conjugated to a first bacterial toxoid and 19F is conjugated to a second bacterial toxoid. Vaccines, methods of making vaccines and uses of the vaccines are also described.
    Type: Application
    Filed: December 20, 2006
    Publication date: January 15, 2009
    Applicant: GLAXOSMITHKLINE BIOLOGICALS S.A.
    Inventors: Ralph Leon Biemans, Nathalie Marie-Josephe Garcon, Philippe Vincent Hermand, Jan Poolman, Marcelle Paulette Van Mechelen
  • Vaccine
    Publication number: 20090017072
    Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, an immunogenic composition for infants is provided comprising a multivalent Streptococcus pneumoniae vaccine comprising 2 or more capsular saccharide conjugates from different serotypes, wherein the composition comprises a serotype 22F saccharide conjugate. Such a vaccine may be used in infant populations to reduce the incidence of elderly pneumococcal disease such as exacerbations of COPD and/or IPD.
    Type: Application
    Filed: December 20, 2006
    Publication date: January 15, 2009
    Applicant: GLAXOSMITHKLINE BIOLOGICALS S.A.
    Inventors: Ralph Leon Biemans, Nathalie Marie-Josephe Garcon, Philippe Vincent Hermand, Jan Poolman, Marcelle Paulette Van Mechelen
  • Pneumococcal Polysaccharide Conjugate Vaccine
    Publication number: 20090010959
    Abstract: The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, a multivalent Streptococcus pneumoniae immunogenic composition is provided with various conjugated capsular saccharides from different S. pneumoniae serotypes conjugated to 2 or more different carrier proteins, where the composition comprises serotype 19F capsular saccharide conjugated to diphtheria toxoid (DT) or CRM197, optionally wherein 19F is the only saccharide in the composition conjugated to diphtheria toxoid (DT) or CRM197.
    Type: Application
    Filed: December 20, 2006
    Publication date: January 8, 2009
    Inventors: Ralph Leon Biemans, Nathalie Marie-Josephe Garcon, Philippe Vincent Hermand, Jan Poolman, Marcelle Paulette Van Mechelen
  • Vaccines
    Patent number: 7169391
    Abstract: The present invention provides vaccine compositions comprising an oil-in-water emulsion optionally with 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccine compositions are potent induces of a range of immune responses.
    Type: Grant
    Filed: August 10, 2005
    Date of Patent: January 30, 2007
    Assignee: Smithkline Beecham Biologicals (S.A.)
    Inventors: Patricia Marie Momin, Nathalie Marie-Josephe Garcon
  • Vaccines
    Publication number: 20060182753
    Abstract: The present invention provides vaccine compositions comprising an oil-in-water emulsion optionally with 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccine compositions are potent induces of a range of immune responses.
    Type: Application
    Filed: August 10, 2005
    Publication date: August 17, 2006
    Inventors: Patricia Marie Momin, Nathalie Marie-Josephe Garcon
  • Vaccines
    Patent number: 7029678
    Abstract: The present invention provides vaccine compositions comprising an oil-in-water emulsion optionally with 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccine compositions are potent induces of a range of immune responses.
    Type: Grant
    Filed: September 3, 2003
    Date of Patent: April 18, 2006
    Assignee: SmithKline Beecham Biologicals (S.A.)
    Inventors: Patricia Marie Momin, Nathalie Marie-Josephe Garcon
  • Vaccines
    Publication number: 20040043038
    Abstract: The present invention provides vaccine compositions comprising an oil-in-water emulsion optionally with 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccines compositions are potent inducers of a range of immune responses.
    Type: Application
    Filed: September 3, 2003
    Publication date: March 4, 2004
    Applicant: SmithKline Beecham Biologicals S.A.
    Inventors: Patricia Marie Momin, Nathalie Marie-Josephe Garcon
  • Vaccines
    Patent number: 6623739
    Abstract: The present invention provides vaccine compositions comprising an oil-in-water emulsion optionally with 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccine compositions are potent inducers of a range of immune responses.
    Type: Grant
    Filed: February 24, 2000
    Date of Patent: September 23, 2003
    Assignee: SmithKline Beecham Biologicals s.a.
    Inventors: Patricia Marie Momin, Nathalie Marie-Josephe Garcon
  • Vaccines
    Patent number: 6146632
    Abstract: The present invention provides vaccine compositions comprising an oil-in-water emulsion optionally with 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccines compositions are potent inducers of a range of immune responses.
    Type: Grant
    Filed: July 2, 1996
    Date of Patent: November 14, 2000
    Assignee: SmithKline Beecham Biologicals s.a.
    Inventors: Patricia Marie Momin, Nathalie Marie-Josephe Garcon