Patents by Inventor Nathalie Scholler

Nathalie Scholler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF GENERATION AND USE OF IN VIVO BIOTINYLATED RECOMBINANT ANTIBODIES
    Publication number: 20080085539
    Abstract: The present invention provides compositions and methods for generating in vivo biotinylated, secreted recombinant polypeptides comprising recombinantly co-expressing in a yeast cell (a) a secreted recombinant polypeptide comprising a biotin accepting site; and (b) a biotin ligase fused to the golgi localization domain so that the biotin ligase is localized to the golgi of the yeast cell where it acts on the biotin-accepting site of the secreted polypeptide as it transits the secretory system.
    Type: Application
    Filed: January 31, 2007
    Publication date: April 10, 2008
    Inventors: Nathalie Scholler, Barbara M. Garvik
  • Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
    Publication number: 20060233794
    Abstract: Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic, immunosuppressive, or other therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of CD70-expressing cancers and immunological disorders, comprising administering to a subject the disclosed pharmaceutical compositions.
    Type: Application
    Filed: February 20, 2004
    Publication date: October 19, 2006
    Applicant: Seattle Genetics, Inc.
    Inventors: Che-Leung Law, Alan Wahl, Nathalie Scholler, Linda Pestano
  • Compositions and methods to regulate an immune response using CD83 gene expressed in tumors and using soluble CD83-Ig fusion protein
    Publication number: 20030219436
    Abstract: This invention describes molecules for regulating the interactions between CD83 and CD83 ligands and their use for therapy of inflammation, autoimmune diseases, transplantation, and cancer. In one particular embodiment, the invention describes CD83Ig soluble fusion proteins that demonstrate functional activity in vivo with utility for immunotherapy.
    Type: Application
    Filed: March 15, 2002
    Publication date: November 27, 2003
    Inventors: Jeffrey A. Ledbetter, Nathalie Scholler, Martha Hayden-Ledbetter, Ingegerd Hellstrom, Karl Erik Hellstrom