Abstract: A collection tank for a mobile vacuum excavator includes a front with a closed end, a rear with an open end, a door configured to be closed over the open end, and a linkage assembly having a first end attached to the door and a second end attached to the body. A first pivotal movement drives the first end and second end away from each other, and a second pivotal movement moves the first end and the second end toward each other. An actuator is attached to the first arm and to the second arm so that actuation of the actuator in a first direction drives the first pivotal movement and actuation of the actuator in a second direction drives the second arm the second pivotal movement.

Abstract: Mixing systems that include a mixer housing and one or more disk assemblies for mixing and processing materials is disclosed. The disks rotate to mix an additive into the material and to carry agglomerated solids toward a discharge of the mixing system. The disks may have a plurality of fingers or lobes which extend from a central portion of the disks.

Abstract: Provided herein are methods of enriching a retinal pigment epithelium (RPE) cell population derived from stem cells. Such a method may comprise removing contaminating cells through the depletion of CD24 positive cells, CD56 positive cells, and/or CD90 positive cells from a starting population of RPE cells.

Abstract: Provided herein are methods of producing a photoreceptor precursor (PRP) cell population derived from stem cells. Further provided herein are methods of using the PRP cell populations, such as for therapeutics.

Abstract: Systems and methods for processing earthen slurries such as slurries of earth cuttings and, in particular, systems and methods that involve two separation units for dewatering the slurry or that involve additive mixing units are disclosed. The systems and methods may include a conveyor such as a drag-slat conveyor that removes slurry from a holding tank at which the material is dumped and toward the separation units to allow the material to be continuously processed and dumped into the holding tank.

Abstract: Transfer systems for receiving and conveying material such as earthen slurries discharged from vacuum excavators are disclosed. The transfer system may include a holding tank and a conveyor such as a drag-slat conveyor that extends into the tank to remove and convey material from the tank. The transfer system includes a hatch. The hatch is moveable from a closed position in which vehicles travel over the hatch to an open position in which the holding tank is open to receive material from the vacuum excavator.

Abstract: The instruments and methods of the present disclosure include an outer shaft, an inner shaft, a roller, and an actuator. In some examples, the outer shaft includes a lumen extending from a proximal end to a distal end. The inner shaft is disposed within the lumen. The roller rotatably is coupled with the distal end at an axis and configured to engage the fixation rod. The actuator operably couples with the inner shaft to translate the inner shaft within the lumen and cause rotation of the roller to impart linear movement on the fixation rod.

Abstract: An osteotomy instrument includes a handle, a first arm assembly, a second arm assembly, a displacement mechanism, and a tuning mechanism. The first arm assembly is pivotably mounted to the handle. The first arm assembly includes a first fastener support configured to hold a fastener. The second arm assembly is pivotably mounted to the handle. The second arm assembly includes a second fastener support configured to hold a fastener. The displacing mechanism includes a dial disposed on the handle. The displacing mechanism is configured to laterally displace a distal end of the first arm assembly and second arm assembly away and towards each other. The dial actuates the displacing mechanism. The tuning mechanism is configured to change an angular position of the first fastener support with respect to the second fastener support.

Abstract: A transverse link with a pair of opposing engagement members having a spherical ball bearing configured to fix a respective screw extender with respect to each other is provided. The spherical bearing is configured to allow the engagement member to rotate in three dimension so as to accommodate the position of a pair of respective screw extenders. The transverse link includes an automatic latching mechanism configured to fixed the spatial distance between the ends of the rod fixation instruments with respect to each other.

Abstract: An instrument for breaking off and retaining the tab of a reduction screw is provided. The instrument includes a breaking arm and a retaining mechanism. The breaking arm is configured to break off an excess portion of the tab of the reduction screw about a weakened section. The retaining mechanism is configured to retain the broken off tab and preventing the tab from falling into a surgical site. The retaining mechanism is further configured to allow the instrument to engage another tab while simultaneously holding a predetermined number of previously broken off tabs. Accordingly, the instrument reduces surgical time as the surgeon may simply move from one reduction screw to another while breaking off the tabs until the instrument can no longer retain additional broken off tabs.

Abstract: A method for reducing a fixation rod is provided. The method minimizes the surgical corridor by performing fixation within the surgical corridor defined by the screw extender. The screw extender is attached to the spinal implant. The method includes the steps of coupling the proximal end of a first cannulated body with the screw extender and rotating a second cannulated body within the first cannulated body. The method proceeds to the step of actuating a rod pusher with a first driving feature so as to engage the rod pusher with the fixation rod. The rod pusher includes a bore. The method proceeds to the step of rotating an inserter shaft within first cannulated body, second cannulated body and bore of the rod pusher, the inserter shaft including a proximal end with a second driving feature and a distal end with a setscrew attachment feature.

Abstract: Separation units for dewatering slurries such as flat-wire belt conveyors are disclosed. In some embodiments, the separation unit includes a tension pulley for maintaining tension in the flat-wire conveyor belt. The flat-wire conveyor belt is looped around the head pulley, tail pulley and tension pulley. In some embodiments, the head pulley and/or tail pulley include teeth for removing material from the mesh openings of the flat-wire belt conveyor.

Abstract: Transfer systems for receiving and conveying material such as earthen slurries discharged from vacuum excavators are disclosed. The transfer system may include a holding tank and a conveyor such as a drag-slat conveyor that extends into the tank to remove and convey material from the tank. The transfer system includes a hatch. The hatch is moveable from a closed position in which vehicles travel over the hatch to an open position in which the holding tank is open to receive material from the vacuum excavator.

Abstract: Systems and methods for processing earthen slurries such as slurries of earth cuttings and, in particular, systems and methods that involve two separation units for dewatering the slurry or that involve additive mixing units are disclosed. The systems and methods may include a conveyor such as a drag-slat conveyor that removes slurry from a holding tank at which the material is dumped and toward the separation units to allow the material to be continuously processed and dumped into the holding tank.

Abstract: The instruments and methods of the present disclosure include an outer shaft, an inner shaft, a roller, and an actuator. In some examples, the outer shaft includes a lumen extending from a proximal end to a distal end. The inner shaft is disposed within the lumen. The roller rotatably is coupled with the distal end at an axis and configured to engage the fixation rod. The actuator operably couples with the inner shaft to translate the inner shaft within the lumen and cause rotation of the roller to impart linear movement on the fixation rod.

Abstract: The instruments and methods of the present disclosure include an outer shaft, an inner shaft, a roller, and an actuator. In some examples, the outer shaft includes a lumen extending from a proximal end to a distal end. The inner shaft is disposed within the lumen. The roller rotatably is coupled with the distal end at an axis and configured to engage the fixation rod. The actuator operably couples with the inner shaft to translate the inner shaft within the lumen and cause rotation of the roller to impart linear movement on the fixation rod.

Abstract: A method, non-transitory computer readable medium and global traffic manager computing device for preventing distributed denial of service attack comprising machine executable code which when executed by at least one processor, causes the processor to perform steps including obtaining network information relating to a request in response to receiving the request. A rating is determined for the obtained network information based on one or more network parameters. An action to be taken for the received request is determined based on a comparison of the determined rating and a threshold rating. The determined action is executed for the received request.

Abstract: Provided herein are methods of enriching a retinal pigment epithelium (RPE) cell population derived from stem cells. Such a method may comprise removing contaminating cells through the depletion of CD24 positive cells, CD56 positive cells, and/or CD90 positive cells from a starting population of RPE cells.

Abstract: A method for reducing a fixation rod is provided. The method minimizes the surgical corridor by performing fixation within the surgical corridor defined by the screw extender. The screw extender is attached to the spinal implant. The method includes the steps of coupling the proximal end of a first cannulated body with the screw extender and rotating a second cannulated body within the first cannulated body. The method proceeds to the step of actuating a rod pusher with a first driving feature so as to engage the rod pusher with the fixation rod. The rod pusher includes a bore. The method proceeds to the step of rotating an inserter shaft within first cannulated body, second cannulated body and bore of the rod pusher, the inserter shaft including a proximal end with a second driving feature and a distal end with a setscrew attachment feature.

Abstract: An instrument for reducing a fixation rod within a screw extender that attaches to a spinal implant includes first, second, and third cannulated bodies and an inserter shaft. The first cannulated body includes a proximal end that couples with the screw extender. The second cannulated body rotates within the first cannulated body and includes a proximal end with a first driving feature and a distal end with an internal threaded portion. The third cannulated body includes a proximal end that engages the internal threaded portion and a distal end with a rod pusher for engaging the fixation rod. The inserter shaft rotates within the third cannulated body and includes a proximal end with a second driving feature and a distal end with a setscrew attachment feature.