Abstract: A polarizing plate and an optical display apparatus are disclosed. A polarizing plate includes a polarizer and a protective layer on at least one surface of the polarizer, and the polarizer includes a polyvinyl alcohol film containing a dichroic substance and contains zinc cations and potassium cations, and the polarizing plate has a value of 0.1 or less, as calculated according to Equation 1.

Abstract: The present disclosure provides: a compound of a specific chemical structure, having excellent activity with respect to BTK degradation; or a pharmaceutically acceptable salt thereof. The present disclosure also provides a composition comprising the compound or pharmaceutically acceptable salts thereof. The present disclosure also provides are pharmaceutical use for treating or preventing BTK-associated diseases (for example, autoimmune diseases or cancer) of the compound, the salt thereof, and the composition comprising same according to the present disclosure. The present disclosure also provides a method for treating or preventing BTK-associated diseases (for example, autoimmune diseases or cancer), comprising administering, to a subject requiring treatment, an effective amount of the compound, the salt thereof, or the composition comprising same according to the present disclosure.

Abstract: The present invention relates to a novel benzopyran derivative useful for preparing a drug for treating cancer, and more specifically, to a novel benzopyran derivative which is a micromolecule having a macrophage inhibitory effect and is useful for preparing a drug for cancer treatment. The drug particularly inhibits the differentiation of immune macrophages to stimulate the immune system, and thus is useful for treating immune-related cancers.

Abstract: A display device includes a substrate, a first barrier layer on the substrate, a lower pattern on the first barrier layer and having a mesh shape defining a disconnection area, a second barrier layer on the first barrier layer, covering the lower pattern, and contacting the first barrier layer in the disconnection area, and a first active pattern on the second barrier layer and overlapping the lower pattern, a gate electrode on the first active pattern and overlapping the lower pattern, a first gate line on the first active pattern extending in a first direction, a second active pattern on the first gate line, a second gate line on the second active pattern extending in the first direction, and a data line on the second gate line extending in a second direction crossing the first direction.

Abstract: Disclosed are: a reinforced composite membrane-type polymer electrolyte membrane which can prevent the loss of an ion conductor even when the ion conductor is chemically deteriorated due to long-term use, and thus has remarkably enhanced mechanical and chemical durability; a method for manufacturing same; and an electrochemical device comprising same. The polymer electrolyte membrane of the present invention comprises: a non-crosslinked ion conductor; and a porous support having a plurality of pores filled with the ion conductor, wherein the porous support comprises a polymer having at least one crosslinking functional group, and the crosslinking functional group is a functional group which, when the ion conductor is deteriorated, can cause crosslinking of the ion conductor by binding to the deteriorated ion conductor.

Abstract: A robot control system for coding education may include: a robot configured to move according to a tangible block including a command, and having a plurality of motors therein; a control unit configured to independently control the plurality of motors; and a tile board corresponding to the space in which the robot moves. The control unit may include a line detection unit configured to detect a line of the tile board in order to check whether the robot moves according to the tangible block. The line detection unit may include line information which is configured in a different manner depending on whether the line is present within a detection radius of the line detection unit. The order information of the tangible block may be read by a block recognition algorithm, and the block recognition algorithm may map the tangible block placed on a 3D space to a 2D space.

Abstract: The present disclosure relates to a coding education block recognition system which can stably recognize a plurality of blocks in an AR (Augmented Reality) environment within a limited time through placement of commands for inputting coding puzzles created in the form of tangible blocks that can be directly handled by the learner's hand.

Abstract: An inter prediction method allows a variable coefficient deep learning model to adaptively learn characteristics of a video; transmits a variable coefficient deep learning model parameter generated from the learning from an image encoding device to an image decoding device; and refers to a virtual reference frame generated by the variable coefficient deep learning model.

Abstract: A method and an apparatus for a messaging service are disclosed. A method of operating a terminal on which an application for a messaging service is installed includes detecting a keyword from a text input through a message input window, cumulatively displaying the detected keyword on a suggest area, setting information about a link to a selected keyword in the text, and separately displaying the selected keyword from a non-selected keyword on the suggest area.

Abstract: Provided is a mesylate salt of methanesulfonic acid and a triazolopyrazine derivative of formula (1), pharmaceutical compositions thereof, methods of making the salt, and therapeutic use thereof:

Abstract: The present invention relates to: a recombinant protein in which an interferon-beta mutein, in which an amino acid residue is substituted, and an antibody binding to a specific antigen are fused together; and a pharmaceutical composition for treating cancer, the composition comprising, as active ingredients, a polynucleotide, an expression vector and a recombinant microorganism, and the recombinant protein. In the recombinant protein, the physical properties of interferon-beta are improved through site-specific mutation, and thus the recombinant protein may have improved biological activity and purification efficiency, and the productivity thereof can be increased.

Abstract: A pixel for a display device includes a light-emitting element, a first transistor including a first electrode electrically connected to a first node and controlling a driving current, a second transistor electrically connected between a data line and the first node and being turned on in response to a first scan signal supplied through a first scan line, a third transistor electrically connected between the second node and a third node electrically connected to a second electrode of the first transistor and being turned on in response to the first scan signal, and a fourth transistor being turned on in response to a second scan signal supplied through a second scan line, and applying a bias voltage to the first transistor. The fourth transistor is turned on at a first frequency. The second and third transistors are turned on at a second frequency different from the first frequency.

Abstract: The present invention relates to an RNA in-vitro transcript mRNA for intracellular expression of a gene of interest and a pharmaceutical composition comprising same for vaccines. When injected into animal cells, the in-vitro transcript mRNA including the gene of interest according to the present invention allows the protein of interest to be expressed in the animal cell in large quantities, and, as such, can be used as a gene vaccine against autoimmune diseases, infectious diseases, cancer- or tumor-related diseases, inflammatory diseases, and so on.

Abstract: A display device includes pixels which are connected to first scan lines, second scan lines, third scan lines, emission control lines, and data lines; a scan driver which supplies a bias scan signal to each of the third scan lines at a first frequency and supplies a scan signal to each of the first scan line and the second scan line at a second frequency which corresponds to an image refresh rate of each of the pixels; an emission driver which supplies an emission control signal to each of the emission control lines at the first frequency; a data driver which supplies a data signal to each of the data lines at the second frequency; and a timing controller which controls driving of the scan driver, the emission driver, and the data driver.

Abstract: Disclosed are: an ionomer dispersion having high dispersion stability while also containing high content of ionomer solids, thus optimizing the ionomer morphology in a polymer electrolyte membrane to allow both the ion conductivity and durability of the polymer electrolyte membrane to be improved; a method for producing the ionomer dispersion; and a polymer electrolyte membrane produced using the method.

Abstract: Proposed is a method in which a server provides a notification message to a user terminal. The method may include determining whether characteristic point-in-time information dependent on a friend account of a user account meets a first condition based on the reference point-in-time information and whether the friend account meets a second condition with respect to the user account. The method may also include identifying the friend account as a friend to be notified based on whether the first condition and the second condition are met. The method may further include providing a message including information about the friend to be notified to the user terminal.

Abstract: Provided is a charging connector for a vehicle, which is coupled to an inlet charging part of an electric vehicle. The charging connector includes a housing configured to provide a coupling space with the inlet charging part, an outlet terminal part including an outlet terminal disposed to pass through the coupling space so as to be in contact with an inlet terminal part installed inside the inlet charging part and a cable connected to the outlet terminal, and a rear holder assembled to one side of the housing to prevent the outlet terminal part from being separated. The rear holder includes a body disposed outside the coupling space and a prevention rib extending from the body to the inside of the coupling space and elastically deformed so that the outlet terminal is hooked and fixed to facilitate assembly of the charging connector for the vehicle and improve durability and safety.

Abstract: A multilayer electronic component includes a body including a capacitance forming portion including a dielectric layer and internal electrodes alternately disposed with the dielectric layer in a first direction and a cover portion disposed on one surface and the other surface of the capacitance forming portion in the first direction, and external electrodes disposed on the body, wherein a secondary phase including Al is disposed at an interface between the internal electrode and the dielectric layer, and the ratio of an area occupied by the secondary phase to an area of the capacitance forming portion is 0.03% or more and 0.40% or less.

Abstract: A pixel circuit includes first to fifth transistors, a capacitor, and a light emitting element. The first transistor is coupled between first and second power lines, and includes a gate electrode coupled to a first node and a back-gate electrode coupled to a second node. The second transistor is coupled between a data line and the first node, and includes a gate electrode coupled to a first scan line. The third transistor is coupled between a third power line and the first node, and includes a gate electrode coupled to a reference scan line. The fourth transistor is coupled between a second node and a fourth power line, and includes a gate electrode coupled to a second scan line. The fifth transistor is coupled between a first power line and the one electrode of the first transistor, and includes a gate electrode coupled to a light-emitting control line.

Abstract: A camsylate salt of D(+)-10-camphorsulfonic acid and a triazolopyrazine derivative of formula (1), pharmaceutical compositions thereof, methods of making the salt, and therapeutic use thereof: