Patents by Inventor Nghe Nguyen-Ba

Nghe Nguyen-Ba has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and methods for the treatment or prevention of infections
    Patent number: 8829030
    Abstract: Compounds represented by formula: Wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: September 9, 2014
    Assignee: Vertex Pharmaceuticals (Canada) Incorporated
    Inventors: Laval Chan Chun Kong, Sanjoy Kumar Das, Nghe Nguyen-Ba, Liliane Halab, Bettina Hamelin, Oswy Z. Pereira, Carl Poisson, Melanie Proulx, Thunkunta Jagadeeswar Reddy, Ming Qiang Zhang
  • COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS
    Publication number: 20130123242
    Abstract: The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
    Type: Application
    Filed: October 26, 2012
    Publication date: May 16, 2013
    Applicant: Vertex Pharmaceuticals (Canada) Incorporated
    Inventors: Laval Chan Chun Kong, Jean Bedard, Sanjoy Kumar Das, Nghe Nguyen-Ba, Oswy Z. Pereira, Thumkunta Jagadeeswar Reddy, Mohammad Arshad Siddiqui, Wuyi Wang, Constantin G. Yannopoulos
  • Compounds and methods for the treatment or prevention of flavivirus infections
    Patent number: 8357718
    Abstract: Compounds represented by formula: wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
    Type: Grant
    Filed: February 4, 2008
    Date of Patent: January 22, 2013
    Assignee: Vertex Pharmaceuticals (Canada) Incorporated
    Inventors: Laval Chan Chun Kong, Sanjoy Kumar Das, Nghe Nguyen-Ba, Liliane Halab, Bettina Hamelin, Oswy Z. Pereira, Carl Poisson, Melanie Proulx, Thumkunta Jagadeeswar Reddy, Zhang Ming-Qiang
  • Compounds and methods for the treatment or prevention of infections
    Patent number: 8329924
    Abstract: The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
    Type: Grant
    Filed: April 7, 2011
    Date of Patent: December 11, 2012
    Assignee: Vertex Pharmaceuticals (Canada) Incorporated
    Inventors: Laval Chan Chun Kong, Jean Bedard, Sanjoy Kumar Das, Nghe Nguyen-Ba, Oswy Z. Pereira, Thumkunta Jagadeeswar Reddy, Mohammad Arshad Siddiqui, Wuyi Wang, Constantin G. Yannopoulos
  • COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS
    Publication number: 20110200553
    Abstract: The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
    Type: Application
    Filed: April 7, 2011
    Publication date: August 18, 2011
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Laval Chan Chun Kong, Jean Bedard, Sanjoy Kumar Das, Nghe Nguyen Ba, Oswy Z. Pereira, Thumkunta Jagadeeswar Reddy, Mohammed Arshad Siddiqui, Wuyi Wang, Constanin G. Yannopoulos
  • Compounds and methods for the treatment or prevention of infections
    Patent number: 7985769
    Abstract: The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
    Type: Grant
    Filed: January 26, 2005
    Date of Patent: July 26, 2011
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Laval Chan Chun Kong, Jean Bedard, Sanjoy Kumar Das, Nghe Nguyen Ba, Oswy Z. Pereira, Thumkunta Jagadeeswar Reddy, Mohammad Arshad Siddiqui, Wuyi Wang, Constanin Yannopoulos
  • Compounds and methods for the treatment or prevention of Flavivirus infections
    Publication number: 20080269481
    Abstract: Compounds represented by formula: wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
    Type: Application
    Filed: February 4, 2008
    Publication date: October 30, 2008
    Inventors: Laval Chan Chun Kong, Sanjoy Kumar Das, Nghe Nguyen-Ba, Liliane Halab, Bettina Hamelin, Oswy Z. Pereira, Carl Poisson, Melaine Proulx, Thumkunta Jagadeeswar Reddy, Zhang Ming-Qiang
  • Compounds and methods for the treatment or prevention of infections
    Patent number: 7402608
    Abstract: Compounds represented by formula: wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
    Type: Grant
    Filed: December 9, 2003
    Date of Patent: July 22, 2008
    Assignee: ViroChem Pharma Inc.
    Inventors: Laval Chan Chun Kong, Sanjoy Kumar Das, Nghe Nguyen-Ba, Liliane Halab, Oswy Z. Pereira, Carl Poisson, Melanie Proulx, Thumkunta Jagadeeswar Reddy, Zhang Ming-Qiang
  • Substituted-1,3-oxathiolanes and substituted-1, 3-dioxolanes with antiviral properties
    Publication number: 20070037975
    Abstract: Disclosed are compounds of the formula wherein R1 is hydrogen or an acyl group having 1 to 16 carbon atoms; R2 is a purine or pyrimidine base or an analogue or derivative thereof; Z is O, S, S?O or SO2; and pharmaceutically acceptable derivatives thereof. Also described are processes for and intermediates of use in their preparation, pharmaceutical compositions containing these compounds, and the use of these compounds in the antiviral treatment of mammals.
    Type: Application
    Filed: October 16, 2006
    Publication date: February 15, 2007
    Inventors: Bernard Belleau, Dilip Dixit, Nghe Nguyen-Ba, Pierette Belleau
  • Substituted-1, 3-oxathiolanes and substituted-1, 3-dioxolanes with antiviral properties
    Publication number: 20070037977
    Abstract: Disclosed are compounds of the formula wherein R1 is hydrogen or an acyl group having 1 to 16 carbon atoms; R2 is a purine or pyrimidine base or an analogue or derivative thereof; Z is O, S, S?O or SO2; and pharmaceutically acceptable derivatives thereof. Also, described are process for and intermediates of use in their preparation, pharmaceutical compositions containing these compounds, and the use of these compounds in the antiviral treatment of mammals.
    Type: Application
    Filed: August 11, 2006
    Publication date: February 15, 2007
    Inventors: Bernard Belleau, Pierette Belleau, Dilip Dixit, Nghe Nguyen-Ba
  • Acetaldehyde acetal compounds, their synthesis, and uses thereof
    Patent number: 7122693
    Abstract: The acetaldehyde compounds, 2-thiobenzoylacetaldehyde diethylacetal, 2-benzoyloxyacetaldehyde bis(2-methoxyethyl)acetal, 2-hydroxyacetaldehyde bis( 2-methoxyethyl)acetal, 2-thiobenzoylacetaldehyde bis(2-methoxy-ethyl)acetal, and 2-thioacetaldehyde bis(2-methoxyethyl)acetal, are useful as intermediates in the synthesis of substituted 1,3-oxathiolanes and substituted 1,3-dioxolanes.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: October 17, 2006
    Assignee: Shire BioChem Inc.
    Inventors: Pierette Belleau, executrix of estate, Dilip M. Dixit, Nghe Nguyen-Ba, Bernard Belleau, deceased
  • Compounds and methods for the treatment or prevention of Flavivirus infections
    Publication number: 20060142347
    Abstract: The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
    Type: Application
    Filed: January 26, 2005
    Publication date: June 29, 2006
    Inventors: Laval Chan Chun Kong, Jean Bedard, Sanjoy Das, Nghe Nguyen Ba, Oswy Pereira, Thumkunta Reddy, Mohammad Siddiqui, Wuyi Wang, Constanin Yannopoulos
  • Compounds and methods for the treatment or prevention of flavivirus infections
    Patent number: 6936629
    Abstract: The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: August 30, 2005
    Assignee: ViroChem Pharma Inc.
    Inventors: Laval Chan Chun Kong, Oswy Z. Pereira, Nghe Nguyen-Ba, Thumkunta Jagadeeswar Reddy, Sanjoy Kumar Das, Mohammad Arshad Siddiqui
  • Pyridine carboxamide and methods for inhibiting HIV integrase
    Publication number: 20050176767
    Abstract: Compounds of formula I: wherein R1, R2, R4, R10, R11, and Q are as defined herein, and their pharmaceutically acceptable salts, are useful in the prevention or treatment of HIV infections.
    Type: Application
    Filed: October 29, 2004
    Publication date: August 11, 2005
    Inventors: Laval Chan Chun Kong, Ming-Qiang Zhang, Liliane Halab, Nghe Nguyen-Ba, Bingcan Liu
  • Substituted 1,3-oxathiolanes
    Patent number: 6903224
    Abstract: Substituted 1,3-oxathiolanes, such as cis- and trans-2-ethoxycarbonyl-5-hydroxy-1,3-oxathiolane and cis- and trans-2-ethoxycarbonyl-5-acetoxy-1,3-oxathiolane, are suitable as intermediates for the production of substituted 1,3-oxathiolanes nucleoside analogs having antiviral properties.
    Type: Grant
    Filed: February 12, 2002
    Date of Patent: June 7, 2005
    Assignee: BioChem Pharma Inc.
    Inventors: Pierette Belleau, Dilip M. Dixit, Nghe Nguyen-Ba, Bernard Belleau
  • Compounds and methods for the treatment or prevention of Flavivirus infections
    Patent number: 6887877
    Abstract: The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating Flaviviridae viral infection.
    Type: Grant
    Filed: June 11, 2002
    Date of Patent: May 3, 2005
    Assignee: ViroChem Pharma Inc.
    Inventors: Laval Chan Chun Kong, Jean Bedard, Sanjoy Kumar Das, Nghe Nguyen Ba, Oswy Z. Pereira, Stephen Joseph Shuttleworth, Mohammad Arshad Siddiqui, Wuyi Wang
  • Compounds and methods for the treatment or prevention of Flavivirus infections
    Patent number: 6881741
    Abstract: The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
    Type: Grant
    Filed: June 11, 2002
    Date of Patent: April 19, 2005
    Assignee: ViroChem Pharma Inc.
    Inventors: Laval Chan Chun Kong, Jean Bedard, Sanjoy Kumar Das, Nghe Nguyen Ba, Oswy Z. Pereira, Thumkunta Jagadeeswar Reddy, Mohammad Arshad Siddiqui, Wuyi Wang, Constanin Yannopoulos
  • Compounds and methods for the treatment or prevention of Flavivirus infections
    Publication number: 20050009804
    Abstract: Compounds represented by formula: wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
    Type: Application
    Filed: December 9, 2003
    Publication date: January 13, 2005
    Inventors: Laval Chan Chun Kong, Sanjoy Das, Nghe Nguyen-Ba, Liliane Halab, Bettina Hamelin, Oswy Pereira, Carl Poisson, Melanie Proulx, Thumkunta Reddy, Zhang Ming-Qiang
  • Substituted-1,3-oxathiolanes and substituted-1,3-dioxolanes with antiviral properties
    Publication number: 20040254201
    Abstract: Disclosed are compounds of the formula
    Type: Application
    Filed: July 9, 2004
    Publication date: December 16, 2004
    Inventors: Bernard Belleau, Pierette Belleau, Dilip M. Dixit, Nghe Nguyen-Ba
  • Use of 1,3-oxathiolane nucleoside analogues in the treatment of hepatitis B
    Patent number: RE39155
    Abstract: Use of a compound of formula (I) or a pharmaceutically acceptable derivative thereof in the manufacture of a medicament for the treatment of hepatitis B is disclosed.
    Type: Grant
    Filed: January 3, 1992
    Date of Patent: July 4, 2006
    Assignee: Shire BioChem Inc.
    Inventors: Pierrette Belleau, Nghe Nguyen-Ba, Bernard Belleau