Abstract: The invention relates to genetic incorporation of 2,3-diamino propionic acid (DAP) into polypeptides, to unnatural amino acids comprising DAP, to a tRNA synthetase for charging tRNA with unnatural amino acids comprising DAP, and to methods of using the resulting polypeptides, for example in capturing substrates and/or intermediates in enzymatic reactions. The invention also relates to compounds of formula (I) or (II): or salts, solvates, tautomers, isomers or mixtures thereof.

Abstract: Methods, systems, and computer programs are directed to the implementation of configurable hierarchical schedulers with multiple levels, where each level may use one of several types of queueing mechanisms. A configurable, hierarchical scheduler is designed to handle large scale processing of requests (e.g., transmitting outgoing messages). The hierarchical scheduler distributes the loads to different queues handling different types of messages (e.g., by user ID, by Internet Address (IP), by schedule). The different layers of the hierarchical scheduler are configurable to queue and schedule traffic based on many factors, such as IP address, handling reputation, available downstream bandwidth, fairness, concurrency rates to handle multiple constraints, scheduling per client, time of delivery constrains, rate limits per user, domain scheduling per user, concurrency throttling per outbound channel, and sharing global rate limits across service processors.

Abstract: Methods and systems for generation of shape data for a set of electronic designs include inputting a set of shape data, where the set of shape data represents a set of shapes for a device fabrication process. A convolutional neural network is used on the set of shape data to determine a set of generated shape data, where the convolutional neural network comprises a generator trained with a set of pre-determined discriminators. The set of generated shape data comprises a scanning electron microscope (SEM) image.

Abstract: The present invention relates to a battery comprising: -i) at least two electrochemical elements (d) connected to one another by a connection part (c), each electrochemical element comprising a container, -ii) a material arranged between said at least two electrochemical elements, and -iii) at least one disconnection device, said device comprising: a heat-activatable element (a) able to deform when its temperature reaches a threshold value, the heat-activatable element being arranged such that, when its temperature reaches said threshold value, it disconnects the connection part (c) from at least one electrochemical element (d) through its deformation, said heat-activatable element not contributing to the conduction of electric current when an electric current flows through said electrochemical elements, said heat-activatable element being placed in contact with the connection part (c) and with a current output terminal.

Abstract: A fin sealer and method to seal a radially outwardly directed fin of a tubular web structure by directing the fin through a nip between a first and a second fin sealing rollers while communicating heat to the fin through at least one of the fin sealing rollers is provided. The fin sealer is configured to maintain a nominal face-to-face relation between an outer annulus of the first fin sealing roller and an outer annulus of the second fin sealing roller with a flexible connection between a hub element of the second fin sealing roller with the outer annulus of the second fin sealing roller.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a wireless device may perform a listen-before-talk (LBT) procedure for a narrowband communication that provides time and frequency synchronization and/or scheduling information for an ultra-wideband (UWB) communication. The wireless device may transmit the narrowband communication in response to the LBT procedure being successful. The wireless device may transmit the UWB communication based at least in part on the time and frequency synchronization and/or scheduling information. Numerous other aspects are described.

Abstract: The disclosure presents processes to automatically generate one or more set of fault segments from a fault plane pointset. The processes can identify a predominant direction and derive a set of fault segments from the fault plane pointset, where the fault segments are generated by using slices of data from the fault plane pointset that are perpendicular to the predominant direction. For each slice of data, the fault segments can be analyzed with neighboring fault segments to determine if they are overlapping. Fault segments that block or overlap other fault segments can be assigned to a different subset of fault segments from the underlying fault segments. Gaps in the fault plane pointset, and the resulting set of fault segments, can be filled in by merging neighboring fault segments above and below the gap if the neighboring fault segments satisfy a criteria for filling the gap.

Abstract: The present disclosure describes medical imaging systems and methods configured to generate medical images based on undersampled imaging data. The images may be generated by applying a neural network trained with samples of known fully sampled data and undersampled data derived from the known fully sampled data to a acquired sparsely sampled data. The training of the neural network may involve training adversarial generative network including a generator and a discriminator. The generator is trained with sets of known undersampled data until the generator is capable of generating estimated image data, which the classifier is incapable of differentiation as either real or fake, and the trained generator may then be applied to unknown undersampled data.

Abstract: A system for monitoring performance of a rope includes a drawn form factor that has a plurality of radio-frequency identification (RFID) devices (e.g., embedded therein). The form factor is integrated into a core portion of the rope. Each RFID device is configured to transmit a corresponding message to at least one receiver in response to an interrogation initiated by at least one transmitter. The messages enable the determination of at least one characteristic of the rope based on a spatial relationship of the plurality of RFID devices and a timing of the received messages.

Abstract: The disclosed embodiments include computerized methods, systems, and devices, including computer programs encoded on a computer storage medium, for generating terms of a search query based on a user's spoken utterances, identifying multiple cross-platform messages based on the generated terms, and to generating, via a presentation device, a single interface that enables the user to interact with identified messages. Based on a spoken utterance, the disclosed embodiments may determine user-specified search terms and/or criteria, and based on the user-specified search terms and/or criteria, may obtain cross-platform message data that corresponds to the search query. The communications device may generate one or more interface elements that describe corresponding ones of the cross-platform messages, which may be presented within a unified graphical user interface or voice-user interface by a communications device.

Abstract: Provided herein are enzymes, cells, and methods to optimize the production of cannabinoids in micro-organisms.

Abstract: This disclosure relates to antigenic EBV polypeptides and their use in eliciting antibodies against EBV. Also disclosed are antigenic polypeptides comprising an EBV polypeptide and a ferritin protein.

Abstract: Disclosed are a microfluidic device and a sample analysis apparatus using the microfluidic device.

Abstract: Disclosed herein are systems and methods that allow for secure access to websites and web-based applications. Also described are systems and methods for secure use and retention of user credentials, as well as methods for dynamic authentication of users and integrity checking of service providers in online environments. Thus, described in the present specification are systems and methods for constructing and destroying private, secure, browsing environments (a secure disposable browser), insulating the user from the threats associated with being online for the purposes of providing secure, policy-based interaction with online services.

Abstract: An airsoft pellet receptacle device. The device may comprise a hollow body having a tapered helical shape. The hollow body may comprise a first opening at a first end of the hollow body, and a second opening at a second end of the hollow body. A diameter of the hollow body may decrease from the first end to the second end. The device may further comprise a base component comprising a pellet inlet, a collection chamber, and a hollow path within the base component connecting the pellet inlet to the collection chamber. In some embodiments, the second end of the hollow body may be coupled to the pellet inlet of the base component. Pellets shot into the first opening may travel down the length of the hollow body and through the pellet inlet into the collection chamber for retrieval.

Abstract: According to some embodiments, systems and methods are provided, comprising a classification data store that contains electronic records associated with entity classifications; and the back-end application computer server, coupled to the classification data store, including: a computer processor; and a memory coupled to the computer processor and storing instructions that, when executed by the computer processor, cause the back-end application computer server to: receive a name and an address associated with the name; receive third-party data associated with the name; classify the name as an enterprise type using a classification tool and the third-party data, the classification tool including a trained hybrid machine learning (ML) model; a communication port coupled to the back-end application computer server to facilitate an exchange of data with a remote device via a distributed communication network to support interactive user interface displays that include information about the classification.

Abstract: Optical center is determined on a column-by-column and row-by-row basis by identifying brightest pixels in respective columns and rows. The brightest pixels in each column are identified and a line is fit to those pixels. Similarly, brightest pixels in each row are identified and a second line is fit to those pixels. The intersection of the two lines is the optical center.

Abstract: A catheter for treating a lesion in a body lumen includes an elongate member, an enclosure, and shock wave emitters enclosed by the enclosure. At least one of the shock wave emitters has a different size than at least one of the other emitters. Providing a smaller shock wave emitter at a distal end of the catheter can help make the catheter more navigable through the body lumen.

Abstract: Aspects of the subject disclosure may include, for example, receiving information defining a high-capacity event in a mobility network, receiving information defining a network location of the high-capacity event in the mobility network, automatically configuring one or more network components of the mobility network according to a set of high-capacity parameters, the one or more network components associated with the network location of the high-capacity event, limiting access to the mobile network to specific users according to the high-capacity parameters, and after the high-capacity event, automatically configuring the one or more network components of the mobile network according to a set of reversion parameters. Other embodiments are disclosed.

Abstract: Systems, methods, and software are disclosed herein for an iterative process of visualization generation. In an implementation, a computing device receives a user request to generate a visualization. The computing device submits a first prompt to a foundation model to obtain code for generating an instance of the visualization requested by the user. The computing device generates an instance of the visualization using the code. The computing device submits the instance of the visualization to an image model to obtain a description of the instance and submits a second prompt to the foundation model to obtain an evaluation of the instance of the visualization with respect to the visualization requested by the user, including the description produced by the image model.