Abstract: Systems and methods for designing and implementing patient-specific surgical procedures and/or medical devices are disclosed. In some embodiments, a method includes receiving a patient data set of a patient. The patient data set is compared to a plurality of reference patient data sets, wherein each of the plurality of reference patient data sets is associated with a corresponding reference patient. A subset of the plurality of reference patient data sets is selected based, at least partly, on similarity to the patient data set and treatment outcome of the corresponding reference patient. Based on the selected subset, at least one surgical procedure or medical device design for treating the patient is generated.

Abstract: A system and computer-implemented method for manufacturing an orthopedic implant involves analyzing tissue characteristics based on image data of anatomy. Image data of a patient can be analyzed to identify at least one tissue characteristic at different locations along anatomic elements of anatomy of interest. A patient-specific implant configuration can be determined based on the analysis of the image data of a patient.

Abstract: Systems and methods for designing and implementing patient-specific surgical procedures and/or medical devices are disclosed. In some embodiments, a method includes receiving a patient data set of a patient. The patient data set is compared to a plurality of reference patient data sets, wherein each of the plurality of reference patient data sets is associated with a corresponding reference patient. A subset of the plurality of reference patient data sets is selected based, at least partly, on similarity to the patient data set and treatment outcome of the corresponding reference patient. Based on the selected subset, at least one surgical procedure or medical device design for treating the patient is generated.

Abstract: A computer-implemented method for designing a patient-specific orthopedic implant can include creating a user account associated with a patient. A patient-specific orthopedic implant can be designed based on patient data and imaging data. A healthcare provider can provide feedback for a design of the patient-specific orthopedic implant, treatment protocol, or other aspects of treatment. The patient can provide data and feedback.

Abstract: A system and computer-implemented method for manufacturing an orthopedic implant involves segmenting features in an image of anatomy. Anatomic elements can be isolated. Spatial relationships between the isolated anatomic elements can be manipulated. Negative space between anatomic elements is mapped before and/or after manipulating the spatial relationships. At least a portion of the negative space can be filled with a virtual implant. The virtual implant can be used to design and manufacture a physical implant.

Abstract: A personalized fixation system includes a surgical planning software tool configured to adjust relationships of relevant anatomy of a subject, at least one bone anchor, a plate having a shape that does not conform to a single plane, the plate configured to accept the at least one bone anchor, wherein the shape of the plate is at least partially determined by the surgical planning software tool, and wherein the plate includes at least one node having a hole configured to receive the at least one bone anchor, and a locking element configured to connect the at least one bone anchor to the plate, wherein the plate is manufactured using additive manufacturing.

Abstract: An interbody implant system for use in the spine includes a base comprising two or more bone contacting surfaces, at least one recess in at least one of the two or more bone contacting surfaces, the recess configured for containing a tooth, a deployable tooth to provide fixation between the base and the anatomy of a subject, a break-away bridge between the tooth and the base for providing a first relative position between the tooth and the base, and a locking mechanism for providing a second relative position between the tooth and the base.

Abstract: A ventilation system and method with a ventilating tube, a stylet removably disposed within the ventilating tube, and a proximal housing. A proximal housing includes a proximal end that connects to the ventilating tube, a distal end that connects to a ventilating machine, a lumen between the proximal end and distal end, an external wall between the proximal end and distal end, a filter contained within the external wall, surrounding the lumen, and connecting the proximal end and distal end, and a cavity between the filter and the external wall. A proximal housing contains at least one detection element and can be sensitive to carbon dioxide. The same proximal housing contains at least one treatment element to heat, cool, humidify, dehumidify, or provide medication to the lumen of the proximal housing.

Abstract: A ventilation system and method with a ventilating tube, a stylet removably disposed within the ventilating tube, and a proximal housing. A proximal housing includes a proximal end that connects to the ventilating tube, a distal end that connects to a ventilating machine, a lumen between the proximal end and distal end, an external wall between the proximal end and distal end, a filter contained within the external wall, surrounding the lumen, and connecting the proximal end and distal end, and a cavity between the filter and the external wall. A proximal housing contains at least one detection element and can be sensitive to carbon dioxide. The same proximal housing contains at least one treatment element to heat, cool, humidify, dehumidify, or provide medication to the lumen of the proximal housing.