Abstract: A multicore optical fiber that includes a plurality of waveguiding cores disposed in a cladding. The plurality of waveguiding cores include one or more first waveguiding cores that have a first propagation constant and one or more second waveguiding cores that have a second propagation constant, where the first propagation constant differs from the second propagation constant. The one or more first waveguiding cores and the one or more second waveguiding cores are disposed in the cladding in a ring distribution and at least a portion of the ring distribution is arranged based on a quasi-periodic sequence having a plurality of sequence segments. Each sequence segment is determined based on a quasi-periodic function, has an order, and corresponds to an arrangement segment of a first waveguiding cores, a second waveguiding cores, or combinations thereof. The ring distribution includes at least one arrangement segment corresponding with a third-order sequence segment or higher of the quasi-periodic sequence.

Abstract: An electric machine includes a frame and a plurality of electrical components including a rotor assembly and a stator assembly. The electric machine further includes an auxiliary blower mounting arrangement for cooling the electrical components and/or a modular exhaust assembly for noise attenuation, wherein the modular exhaust assembly further has one or more louvers allowing cooling fluid for cooling the electrical components to exit the electric machine.

Abstract: In some embodiments, a method comprises receiving a first signal indicative of a current emotional state of a user, receiving a second signal corresponding to a desired emotional state of the user, and based on the first and second signals, generating a playlist of media content including a first item and an nth item. The first signal can be received from a wearable sensor. Generating the playlist can comprise selecting items of media content, and arranging the media content in a sequential order such that the playlist transitions from the first item toward the nth item. The method can further comprise playing back, via a playback device, at least the first item of the media content, and while playing back the first item, receiving a third signal indicative of an updated emotional state of the user.

Abstract: An equipment front end module may include an equipment front end module body forming an equipment front end module chamber. The equipment front end module body may include plurality of walls. One or more load locks or process chambers may be coupled to one or more first walls. One or more load ports may be provided in one or more second walls, wherein each of the one or more load ports are configured to dock a substrate carrier. A plurality of alignment pedestals may be housed within the equipment front end module chamber. A load/unload robot may be at least partially housed within the equipment front end module chamber, wherein the load/unload robot may include a plurality of blades. Other apparatus and methods are disclosed.

Abstract: The present invention provides engineered phenylalanine ammonia-lyase (PAL) polypeptides and compositions thereof, as well as polynucleotides encoding the engineered phenylalanine ammonia-lyase (PAL) polypeptides.

Abstract: The present disclosure provides antibodies that specifically bind to human OX40 receptor (OX40) and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human OX40 and modulate OX40 activity, e.g., enhance, activate, or induce OX40 activity, or reduce, deactivate, or inhibit OX40 activity. The present disclosure also provides methods for treating disorders, such as cancer, by administering an antibody that specifically binds to human OX40 and modulates OX40 activity, e.g., enhances, activates, or induces OX40 activity. Also provided are methods for treating autoimmune or inflammatory diseases or disorders, by administering an antibody that specifically binds to human OX40 and modulates OX40 activity, e.g., reduces, deactivates, or inhibits OX40 activity.

Abstract: Disclosed herein inter alia are compositions and methods useful in the treatment of cancer and for modulating the activity of Aurora A kinase and/or a Myc family protein.

Abstract: An improved operating system for use in an architectural-structure covering for extending and retracting a covering portion is disclosed. The operating system including an operating element for raising the covering portion and for transitioning the operating system between a retraction mode to raise the covering and an extension mode to lower the covering. To transition between the retraction and extension modes, an operator may move the operating element in a preset direction, such as, in the manner akin to a switch. For example, moving the operating element in a first direction (e.g., a rearward direction away from the operator) shifts the operating system into the retraction mode, while moving the operating element in a second direction (e.g., a forward motion toward the operator) shifts the operating system into the extension mode. In one embodiment, the first and second directions may be transverse to a longitudinal axis of the architectural-structure covering.

Abstract: Method for estimating a pure tone hearing threshold or a pure tone audiogram of a person with a non-calibrated audio-system, comprising the steps of performing a supra-threshold test at least over a portion of the audible frequency spectrum, wherein the audible frequency spectrum ranges particularly from 16 Hz to 20.

Abstract: Methods and apparatus for cleaning a surface with a cleaning device having a body with a handle, a connector, and one or more cleaning heads that are removably attached to the cleaning device. Each cleaning head include a lower surface arranged to contact a surface to be cleaned and a dirt collection chamber permanently attached to the cleaning head. The cleaning head may include a support structure to support the dirt collection chamber and a cleaning sheet. The cleaning head also may include a suction nozzle. At least a portion of the dirt collection chamber may be made of a filter material.

Abstract: A method of project management is provided. The method comprises receiving identity of a number of customers requiring data migration and receiving a target completion date for data migration for each customer. A number of data migration implementations are identified for all customers. A number of tasks required for each implementation is calculated, as is a required time for completion of each task. A number of people are then identified from a candidate pool to assign to complete the implementations. An estimated completion date is calculated for data migrations for each customer according to a total required time for all implementations and the number of people assigned to complete the implementations. The target completion date and estimated completion date for each customer are displayed in a user interface.

Abstract: A system that incorporates the subject disclosure may include, for example, a processor coupled to a memory storing instructions and to a near field sensor. Execution of the instructions can cause the processor to perform operations including defining a zone corresponding to a portion of an accessory comprising the sensor, detecting a gesture of an object in the zone by sensing the object with the sensor, determining that the gesture is a new gesture not previously associated with the zone and not previously associated with a gaming action controlling presentations produced by a gaming application, associating the gesture with the zone and with the gaming action, subsequently detecting the gesture in the zone, obtaining the gaming action associated with the gesture, and transmitting the gaming action to the gaming application. Other embodiments are disclosed.

Abstract: According to certain aspects, a computer system may be configured to aggregate and analyze data from a plurality of data sources. The system may obtain data from a plurality of data sources, each of which can include various types of data, including email data, system logon data, system logoff data, badge swipe data, employee data, job processing data, etc. associated with a plurality of individuals. The system may also transform data from each of the plurality of data sources into a format that is compatible for combining the data from the plurality of data sources. The system can resolve the data from each of the plurality of data sources to unique individuals of the plurality of individuals. The system can also determine an efficiency indicator based at least in part on a comparison of individuals of the unique individuals that have at least one common characteristic.

Abstract: In particular embodiments, a Data Transfer Risk Identification System may be configured to analyze one or more data systems (e.g., data assets), identify data transfers between/among those systems, apply data transfer rules to each data transfer record, perform a data transfer assessment on each data transfer record based on the data transfer rules to be applied to each data transfer record, and calculate a risk score for the data transfer based at least in part on the one or more data transfer risks associated with the data transfer record.

Abstract: An energy-absorbing structure for a vibration isolator includes a conical disc spring member having a first end including a central opening and a second end opposite the first end. The structure also includes at least one spacer having a base portion with a first side. The base portion first side defines a cavity structured to receive therein a second end of the spring member. The cavity has a floor, and a second end of the spring member is positioned in contact with the floor. The floor includes an opening formed therein and positioned so as to reside opposite the first end of the spring member when the second end of the spring member is positioned in contact with the cavity floor. The opening is structured to receive at least a portion of the first end of the spring member therein during an inversion of the spring member.

Abstract: Embodiments of the present invention are directed to fabrication methods and resulting structures for subtractively forming a top via using a hybrid metallization scheme. In a non-limiting embodiment of the invention, a surface of a conductive line is recessed below a topmost surface of a first liner layer. The first liner layer can be positioned between the conductive line and a dielectric layer. A top via layer is formed on the recessed surface of the conductive line and a hard mask is formed over a first portion of the top via layer. A second portion of the top via layer is removed. The remaining first portion of the top via layer defines the top via. The conductive line can include copper while the top via layers can include ruthenium or cobalt.

Abstract: Methods, apparatus, and processor-readable storage media for identifying and determining the criticality of enterprise assets using network traffic information are provided herein. An example computer-implemented method includes capturing network session information from an enterprise network; identifying multiple assets within the enterprise network by processing the captured network session information; determining, for each of the identified assets, one or more predefined features of the asset based at least in part on the processing of the captured network session information; determining, for each of the identified assets, a level of criticality associated with the asset based at least in part on the one or more determined features of the asset; and outputting the level of criticality and an identifier of the asset associated therewith to a security-related system, wherein the level of criticality and the asset identifier are used by the security-related system to take at least one automated action.

Abstract: A ventilator includes a bidirectional breath detection airline and a flow outlet airline. The flow outlet airline includes an airline outlet. The flow outlet airline is configured to be connected to an invasive ventilator circuit or a noninvasive ventilator circuit. The breath detection airline includes airline inlet. The airline inlet is separated from the airline outlet of the flow outlet airline. The ventilator further includes a pressure sensor in direct fluid communication with the breath detection airline. The pressure sensor is configured to measure breathing pressure from the user and generate sensor data indicative of breathing by the user. The ventilator further includes a controller in electronic communication with the pressure sensor. The controller is programmed to detect the breathing by the user based on the sensor data received from the pressure sensor.

Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.