Abstract: A light clamp apparatus includes a clamp configured to affix the light clamp apparatus to an object. The light clamp apparatus also includes a light assembly configured to removably attach to the clamp at least at two different positions on the clamp, the light assembly including a magnet, whereby the light assembly is removably attachable to a surface comprising a ferromagnetic metal. The clamp includes a slide bar comprising a first end and a second end, a first jaw coupled to the first end, and a body slidably receiving the slide bar having a second jaw opposing the first jaw. The clamp further includes a drive assembly for moving the slide bar in a first direction.

Abstract: The present invention relates to processes of making components for electronic and optical devices using laser processing and devices comprising such components. Such process uses a laser to introduce chemical and/or structural changes in substrates and films that are the raw materials from which components for electronic and optical devices are made. Such process yields components that can have one or more electronic and/or optical functionalities that are integrated on the same substrate or film. In addition, such process does not require large-scale clean rooms and is easily configurable. Thus, rapid device prototyping, design change and evolution in the lab and on the production side is realized.

Abstract: A steerable catheter system comprises an elongate catheter body including a distal end and a proximal end. The system also comprises a control mechanism coupled to the proximal end of the elongate catheter body. The control mechanism includes a rotatable steering control element configured to articulate the distal end of the elongate catheter body. The system also includes a lumen extending through the elongate catheter body and the control mechanism and terminating at the distal end of the elongate catheter body. The system also includes a valve coupled to the lumen. The valve is configured to couple a fluid delivery system to the lumen and to enable delivery of an instrument into the lumen.

Abstract: Systems and methods for reducing latency in transactions are described herein. In an embodiment, an application edge acts as a system of record for an application. When a client computing device sends a request to perform a transaction to the application, the application edge receives the request and, without forwarding the request to a backend computing network, searches a transaction datastore stored at the application edge for the account balance and responds to the client computing device with the account balance. The client computing device then determines that a transaction can be performed and sends a request to perform the transaction to the application. The application edge passes this request to the backend computing network which performs the requested transaction. The application edge then uses a webhook infrastructure to update each transaction datastore stored at the application edge.

Abstract: Structures for an optical fiber groove and methods of forming a structure for an optical fiber groove. A photonics chip includes a substrate and an interconnect structure over the substrate. The photonics chip has a first exterior corner, a second exterior corner, and a side edge extending from the first exterior corner to the second exterior corner. The substrate includes a groove positioned along the side edge between the first exterior corner and the second exterior corner. The groove is arranged to intersect the side edge at a groove corner, and the interconnect structure includes metal structures adjacent to the first groove corner. The metal structures extend diagonally in the interconnect structure relative to the side edge of the photonics chip.

Abstract: Systems and techniques that facilitate hybrid readout packaging for quantum multichip bonding are provided. In various embodiments, an interposer can have a first quantum chip and a second quantum chip. In various aspects, a readout resonator (e.g., input/output port) of one or more qubits on the first quantum chip can be routed to an inner portion of the interposer. In various instances, the inner portion can be located between the first quantum chip and the second quantum chip. In various aspects, routing the readout resonator to the inner portion can reduce a number of crossings and/or intersections between input/output lines on the interposer and connection buses between qubits on the interposer.

Abstract: The present invention relates to processes of making components for electronic and optical devices using laser processing and devices comprising such components. Such process uses a laser to introduce chemical and/or structural changes in substrates and films that are the raw materials from which components for electronic and optical devices are made. Such process yields components that can have one or more electronic and/or optical functionalities that are integrated on the same substrate or film. In addition, such process does not require large-scale clean rooms and is easily configurable. Thus, rapid device prototyping, design change and evolution in the lab and on the production side is realized.

Abstract: A storage curtain device for hanging from the front wall of a pickup truck bed, provided with storage features for stowing small tools, equipment, and cargo. The storage curtain device comprises a curtain body portion secured to a cap, the cap designed to fit over the upper edge of the front wall of the pickup truck bed.

Abstract: A head-mounted device includes a device housing, a display device, an optical system, and a headband. The head-mounted device also includes a first headband connector that includes a headband-side connector portion that is connected to the headband at a first end of the headband and a device-side connector portion that is connected to the device housing. The first headband connector is movable between a disconnected position, in which the headband-side connector portion is disconnected from the device-side connector portion, and a connected position, in which the headband-side connector portion is connected to the device-side connector portion. The first headband connector also includes paired magnetic components that are configured to attract the headband-side connector portion and the device-side connector portion to one another to urge the first headband connector to move to the connected position.

Abstract: Techniques are provided for object store mirroring. Data within a storage tier of a node may be determined as being data to tier out to a primary object store based upon a property of the data. A first object is generated to comprise the data. A second object is generated to comprise the data. The first object is transmitted to the primary data store for storage in parallel with the second object being transmitted to a mirror object store for storage. Tiering of the data is designated as successful once acknowledgements are received from both the primary object that the first object was stored and the mirror object store that the second object was stored.

Abstract: Certain aspects relate to admittance control modes for a robotic surgery system. The admittance control modes can be based on detecting and/or measuring forces (rotational and/or nonrotational) on a robotic arm and moving the robotic arm in response to such interactions. The forces can include direct manual interaction with the robotic arm by a clinician. The movement of the robotic arm can be within a nullspace that maintains the positions of a medical instrument.

Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.

Abstract: The present application provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.

Abstract: Methods and systems for data governance in a dispersed storage network using bucket templates are disclosed. A method includes: creating, by a computing device, a bucket template in a dispersed storage network (DSN) based on a first request, the bucket template including at least a first bucket parameter and at least one allowed value for the first bucket parameter; receiving, by the computing device, a second request to create a bucket in the DSN, the second request including at least a first value for the first bucket parameter; and creating, by the computing device, the bucket based on the first value for the first bucket parameter in the second request and the at least one allowed value for the first bucket parameter in the bucket template.

Abstract: A computer implemented method manages access to resources of a cloud platform. The method includes retrieving, at a computing device of the cloud platform, context data and load policies for a requestor and an identified resource, combining, by the computing device, loaded policies with context data into a combined data structure, evaluating, by the computing device, a resource request and apply policies for requestor based on role of requestor using the combined data structure, generating, by the computing device, resource permissions for the requestor, and returning, by the computing device, resource permissions to the requestor.

Abstract: The present invention relates to heterotandem bicyclic peptide complexes which comprise a first peptide ligand, which binds to a component present on an immune cell, conjugated via a linker to a second peptide ligand, which binds to a component present on a cancer cell. The invention also relates to the use of said heterotandem bicyclic peptide complexes in preventing, suppressing or treating cancer.

Abstract: Various systems and methods for modeling a manufacturing assembly line are disclosed herein. Some embodiments relate to operating a processor to receive cell data and line production data, determine one or more production associations between the cell data and the line production data; evaluate the one or more production associations to identify one or more critical production associations; retrieve the cell data and the line production data associated with the one or more critical production associations; and train a predictive model with the retrieved cell data and the retrieved line production data to predict the production level of the manufacturing assembly line.

Abstract: Techniques are disclosed for deploying game-based therapy correlated with, but independent from, an executing game program. In general, game content within a display can be improved with an overlay of visual therapeutic content such as a visual indicator of a current emotional or physiological state, along with visual features or effects that alter game difficulty. A variety of visual effects can usefully be integrated with third-party game content with requiring direct computation access to the executing game code. For example, effects such as dimming, fading, pixelating, or fogging can be rendered within active regions of a game window independently from, but correlated with the visual content of, the current game. This is suitable for delivering treatment for a range of cognitive and similar disorders and permits rendering of user-specific therapeutic content in combination with third-party games and gaming platforms.

Abstract: Means and methods for preparing combinatorial libraries of DNA constructs, in particular expression cassettes, including nucleic acid constructs, expression vectors, host cells, methods for preparing host cells, and methods for producing polypeptides of interest, whereby the expression comprises an first intron and a second intron on either side of the polynucleotide to be expressed and a promoter and a terminator. Also claimed is a method of constructing eukaryotic host cells in which the cells are contacted with three polynucleotides and in which the first and second and the second and third are pairwise capable of homologous recombination and of subsequent formation of introns.

Abstract: The systems and methods described herein relate to a dome of a gas turbine assembly configured to suppress pressure pulsations. The systems and methods provide a dome having an aperture configured to surround an injector assembly of a combustor. The dome having a front panel extending radially from the aperture. The systems and methods couple a first cavity to the front panel. The first cavity includes a series of ducts. A first duct of the series of ducts is configured to receive airflow into the first cavity from a compressor and a second set of ducts of the series of ducts and a third duct of the series of ducts are configured to direct airflow to the combustor from the first cavity, wherein the third duct has a larger diameter than the second set of ducts.