Abstract: A retinal imaging system includes a projector, an imaging device, and a controller coupled to an eye tracking system under test. The projector emits a light pattern to be delivered to a pupil of an eye, a location of the pupil being estimated by the eye tracking system under test. The imaging device captures one or more images of a retina of the eye illuminated with at least a portion of the light pattern. The controller determines one or more eye tracking parameters based on the captured one or more images of the retina. The controller compares each determined eye tracking parameter with each of estimated one or more eye tracking parameters, wherein values for the one or more eye tracking parameters are estimated by the eye tracking system under test. The controller characterizes each estimated eye tracking parameter based on the comparison.

Abstract: Protective devices, such as, for example, helmets, have one or more efficient, fluid-containing shock absorbers in place of protective devices' original shock absorbing material to minimize the overall weight of the protective devices. The more efficient, fluid-containing shock absorbers yield improved impact force attenuation but occupy substantially less volume and, consequently, less weight, than the original shock absorbing material.

Abstract: This invention relates to compounds of Formula (I): and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein L1, L2, R1, R2, R3 and n are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.

Abstract: A computer system and method for synchronizing actions associated with media between a media/network device and peripherals. In an example implementation, a system includes a one or more processors configured to receive, by a communication module from a media/network device based on peripheral addressing information, a peripheral payload including a first set of actions and timing information related to media. The one or more processors perform the first set of actions based on the peripheral payload, generate response data for the first set of actions, and transmit the response data to the media/network device via a wireless network.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium for securely attributing application (app) installations while preserving user privacy are described. In one aspect, a method includes a given digital component that can be provided and can include a reference to a software application. A user interaction with the digital component that initiates installation of the application can be detected. The software application can be installed at a client device. The following can be obtained: (i) impression data that reference the software application and (ii) interaction data that reference the software application. Attribution credits for the installation of the software application can be assigned by applying an attribution model to the presentation and interaction data.

Abstract: A sander includes a housing defining a front end and a rear end relative to a direction of travel of the sander on a work surface, an actuator, and a battery platform. The housing supports a motor and has a grip disposed over the motor adjacent the front end and a handle positioned at or adjacent the rear end. The housing further supports a belt drive assembly configured to rotatably support a belt and having a belt plate extending a long a first plane. The actuator is supported by the handle. The battery platform is at least partially supported by and located above the handle. The battery platform defines a battery pack receptacle configured to support a battery pack. The battery platform is oriented along a second plane orientated at an acute angle relative to the first plane.

Abstract: The disclosure provides a method for treating a subject afflicted with a tumor derived from a small cell lung cancer (SCLC) having a high tumor mutational burden (TMB) status comprising administering to the subject a monotherapy comprising an anti-PD-1 antibody or a combination therapy comprising an anti-PD-1 antibody and an anti-CTLA-4 antibody. The present disclosure also provides a method for identifying a subject suitable for treatment with an anti-PD-1 antibody or a combination therapy comprising an anti-PD-1 antibody and an anti-CTLA-4 antibody comprising measuring a TMB status of a biological sample of the subject. A high TMB status identifies the patient as suitable for treatment with an anti-PD-1 antibody or antigen-binding portion thereof. The TMB status can be determined by sequencing nucleic acids in the tumor and identifying a genomic alteration, e.g., a somatic nonsynonymous mutation, in the sequenced nucleic acids.

Abstract: A drug delivery device for delivering a medicament includes a pump first housing, a pump second housing, an inlet fluid path, and an outlet fluid path. The pump first housing is at least partially supporting and/or surrounding a fluid displacement assembly. The pump second housing is at least partially supporting and/or surrounding a drive component for driving the fluid displacement assembly. The inlet fluid path is configured to deliver medicament to the fluid displacement assembly. The outlet fluid path is configured to receive medicament from the fluid displacement assembly. The pump first housing and the pump second housing are removably coupled with each other.

Abstract: A head-mounted-display includes an electronic display emitting image light and a varifocal block receiving the image light and outputting the image light in at least one of the focal planes of the varifocal block. The varifocal block includes a back optical element, a front optical element, and an actuator assembly coupled to the back and front optical element. The front optical element is positioned closer to an exit pupil than the back optical element, and separated from the back optical element by an adjustable distance, the magnitude of which determines in which of the focal planes the image light is presented. The actuator assembly simultaneously adjusts positions of the back optical element and the front optical element to vary the adjustable distance between the back optical element and the front optical element in accordance with an estimated vergence depth of the user.

Abstract: The present disclosure relates to a thermal conductivity vacuum gauge assembly. The assembly comprises a body defining an internal chamber for receiving working gas and a heater element disposed within the chamber. The body is defined by a wall having an outer facing wall surface and an opposing inner facing wall surface. A thermal compensation element and a thermal equalisation element are in thermal communication with the body. The body is made of a material with a first thermal conductivity, and the thermal equalisation element is made of a material with a second thermal conductivity that is higher than the first thermal conductivity. The present disclosure also relates to a thermal conductivity vacuum gauge including the assembly.

Abstract: In one example, an apparatus comprises: multiple distinct sets of photodiodes, wherein each set of photodiodes includes one or more photodiodes, one or more charge sensing units, and a controller. The controller is configured to: transfer charge generated by the one or more photodiodes in response to a different component of incident light to the one or more charge sensing units in order to convert the charge to voltages; perform one or more quantization processes of a plurality of quantization processes corresponding to a plurality of intensity ranges, wherein the one or more quantization processes quantizes the voltages from the one or more charge sensing units to digital values representing components of a pixel of different wavelength ranges; and generate a pixel value based on the at least some of the digital values.

Abstract: The present disclosure relates to a thermal conductivity vacuum gauge assembly. The assembly comprises a body defining an internal chamber for receiving working gas and a heater element disposed within the chamber. The body is defined by a wall having an outer facing wall surface and an opposing inner facing wall surface. A thermal compensation element is enclosed within the wall between the outer and inner facing wall surfaces. The present disclosure also relates to a thermal conductivity vacuum gauge including the assembly.

Abstract: An on-line marketplace provides systems and methods for a mutually beneficial messaging campaign with one or more merchants, in order to promote the merchants' products. One aspect of the messaging campaign includes augmenting the merchants' budgets across multiple commercial channels. The channels may include merchant-operated channels, marketplace-operated channels, and/or third party channels. The marketplace selects when and how to augment the merchants' budgets. The augmented budget comprises an overall content budget for the messaging campaign, including a first budget portion provided by the merchant(s) and a second budget portion provided by the on-line marketplace. The augmented budget may be determined based on a weighted combination of goals of the marketplace and one or more merchants. The augmented budget may be segmented into static and dynamic portions, in which the dynamic portion is varied between channels to determine variables to optimize budget allocation and message performance.

Abstract: A wearable electronic device includes an electrode array for transdermal stimulation of a sensory nerve that itself innervates a body part distal to a worn location of the wearable electronic device. The transdermal stimulation is configured to induce an electrical current or voltage that evokes a sensory impression at an area innervated by the sensory nerve, not at the stimulated sensory nerve itself. In one implementation, the wearable electronic device takes a finger ring form factor worn on a proximal phalanx of an index finger. In this configuration, the wearable electronic device can stimulate a portion of a branch of the median nerve extending through the index finger. Upon stimulation of the median nerve, a user wearing the finger ring may perceive pressure applied to the user's fingertip.

Abstract: A method for correcting artifacts in artificial reality headsets is provided. The method includes coupling a first image portion into a waveguide in a display for an artificial reality device, provided by a first array of pixels, coupling a second image portion into the waveguide in the display, provided by a second array of pixels, directing the first image portion through an eyebox, directing the second image portion through the eyebox, and tiling, in a user's retina, the first image portion and the second image portion to form an image having an extended field of view that includes an overlapping area comprising light provided by the first array of pixels and the second array of pixels. A system including a memory storing instructions and a processor to execute the instructions to cause the system to perform the above method are also provided.

Abstract: A hinge assembly mounted on a housing of form part of an electronic device includes a metal hinge base extending through a mounting hole in a wall of the housing, the hinge base being connected in heat transfer relationship to a metal anchor plate on an inner side of the housing wall. The anchor plate additionally serves as a mounting base for heat-generating electronics inside the housing, the heat-generating electronics being in heat transfer relationship with the anchor plate, so that the anchor plate and the hinge base together form part of a heat transfer path conducting heat from the interior of the housing to an exterior heatsink provided be and external device component.

Abstract: A depth camera assembly for depth sensing of a local area includes an illumination source, an imaging device, and a controller. The illumination source illuminates a local area with light emitted in accordance with emission instructions generated by the controller. The illumination source includes an array of optical sources and an optical assembly. Operation of each optical source in the array is controllable based in part on the emission instructions. The optical assembly is configured to project the light into the local area. The imaging device captures one or more images of at least a portion of the light reflected from one or more objects in the local area. The controller determines depth information for the one or more objects based in part on the captured one or more images.

Abstract: A hydroponic growing system is presented. The system can include multiple growing trays in a vertical arrangement, where a pump supplies the top-most tray and each lower tray is supplied by the overlying tray, and where the plumbing elements for supply and drainage are arranged to one side of the system. The system includes variations to support different crop types within the same system, including removable growing structures for root vegetable, microgreens and supports for vining crops. The system can monitor and adjust the nutrients and other features of the systems water profile to concurrently group multiple crops in differing developing stages.

Abstract: Disclosed herein are related to a system and a method of remotely rendering artificial reality. In one approach, a console determines an expected transmission end time of a first session for wireless transmission of image data indicating an image of artificial reality to a head wearable display. In one approach, the console determines an expected process end time of generating additional data associated with the image of the artificial reality. In one approach, the console compares the expected transmission end time and the expected process end time. The console may transmit, to the head wearable display in the first session, the additional data together with the image data, in response to the expected process end time being less than the expected transmission end time.

Abstract: A hinge assembly mounted on a housing of form part of an electronic device includes a metal hinge member having a hinge post that extends through a mounting hole in a wall of the housing, the hinge post being connected to a metal anchor plate on an inner side of the housing wall to be rotationally and axially fast with the anchor plate. The anchor plate may has an area multiple times the size of a footprint of the hinge member, with fastening the hinge post and the anchor plate in some embodiments being by a welded connection.