Abstract: Described are a system, method, and computer program product for secure client device and consumer authentication. The method includes receiving a primary account number (PAN) of an account of a consumer from a merchant system and determining whether the PAN has been registered with a public key of a public-private key pair of a client device of the consumer. The method also includes, in response to determining that the PAN has been registered, transmitting a login request to a transaction processing system including a device identifier of the client device based on the PAN. The method further includes receiving a login response from the transaction processing system associated with successful authentication of the client device and, in response to receiving the login response, processing a transaction by generating a transaction authorization request message including the PAN to the transaction processing system.

Abstract: Described herein are nucleic acid detection compositions and systems comprising an internal nuclease chain reaction (NCR) for signal amplification and methods of using these NCR-containing compositions and systems.

Abstract: A container having a base and a lid is provided. The lid may be rotatable about a hinge from a closed configuration to an open configuration and may be secured, via one or more latching assemblies. The latch assembly may comprise a latch body, a locking member, a biasing member, and an activating member. The lid may have a handle that has a stowed and a carry position, where the handle may be maintained in the stowed position until acted upon by a first force greater than a threshold force to move the handle from the stowed position to the carry position. Similarly, when in the carry position, the handle may be maintained in the carry position until acted upon by a second force greater than the threshold force to move the handle from the carry position to the stowed position.

Abstract: Automated cold storage unit and systems for storing, monitoring, and maintaining a supply of temperature sensitive pharmaceutical and/or other products in compliance with regulatory requirements are provided. Such units contain an array of independently addressable holding locations for containers with product in one or more controlled temperature zones fitted with temperature sensors. The units include a reader to track product information and status. Product movement within the unit is performed by a computer-controlled robot. A user interface device, preferably in communication with an application service provider to provide remotely managed inventory management and other services, provides users with secure access to the contents of the unit and associated product data and information.

Abstract: A solenoid adapter for a solenoid valve that permits use of different solenoids with different solenoid bowls is provided. Specifically, a reverse flow solenoid adapter enables use of a reverse flow solenoid with a forward flow solenoid bowl, while a forward flow solenoid adapter enables use of a forward flow solenoid with a reverse flow solenoid bowl. The adapters include a lower section to mount into a valve solenoid bowl, an upper portion including an adapter solenoid chamber to receive a solenoid, and flow-reversing passages that duct a vent passage flow path from the valve solenoid bowl to the adapter solenoid chamber such that the flow path transitions from a flow configuration of the valve solenoid bowl to a flow configuration required for the solenoid to function and returns to the flow configuration of the valve solenoid bowl as the path circulates back to the valve solenoid bowl.

Abstract: A method for image generation, preferably including: generating a set of mission parameters for a UAV mission of the UAV associated with aerial scanning of a region of interest; controlling the UAV to perform the mission; generating an image subassembly corresponding to the mission; and/or rendering the image subassembly at a display.

Abstract: The present disclosure relates to certain (2S)—N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

Abstract: In some examples, a distributed computer system includes a plurality of computer nodes, where the plurality of computer nodes include respective programs to cooperate to perform a workload. A first computer node includes a communication proxy between the program of the first computer node and a communication library that supports communications between the program of the first computer node and the programs of other computer nodes of the plurality of computer nodes, and a fault management service to monitor a health of the other computer nodes, and in response to a detection of a fault of a second computer node of the plurality of computer nodes, relaunch the communication proxy. The relaunched communication proxy selects, from a plurality of states, a common state to which the programs are to roll back.

Abstract: A replacement heart valve prosthesis is loaded onto a balloon mounted onto a balloon shaft of a catheter system. The balloon shaft is rotatably engaged with an actuator on the handle of the catheter system. Rotation of the actuator by a first amount in a first direction permits rotation of the heart valve prosthesis by a known amount during the procedure so that alignment of the commissures of the replacement valve with the commissures of the existing valve can be predictably achieved.

Abstract: Authentication tokens, systems, and methods are described. An illustrative method is disclosed to include receiving an electronic file including a digital image, receiving biometric information that is associated with a person, modifying the electronic file with the biometric information such that one or more pixels in the digital image are replaced with the biometric information, and storing the modified electronic file as a digital authentication token to be used in connection with authorized publications of original digital work.

Abstract: This invention relates to compounds of Formula (I): and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein L1, L2, R1, R2, R3 and n are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.

Abstract: Methods and systems are provided for detecting a trip of a user in a vehicle. A method includes: receiving by a processor of a user device, device scan data from one or more communication enabled devices; determining, by the processor, whether the devices listed in the device scan data is a vehicle device; in response to the determining, identifying, by the processor, the vehicle device as a found device; determining, by the processor, whether the found device is listed in a known device list; and generating, by the processor, at least one of a trip start signal and a trip end signal based on whether the found device is listed in the known device list.

Abstract: An aerospace vehicle system, preferably including one or more capsules, and optionally including one or more propulsion modules and/or safety modules. A capsule, preferably including a pressure vessel including a structural frame and one or more windows, and optionally including a cabin. In alternate embodiments, the system can additionally or alternatively function as a terrestrial vehicle, a watercraft, and/or any other suitable vehicle. A method of operation, preferably including operating the aerospace vehicle system in flight, while maintaining a pressure differential between the pressure vessel interior and an environment surrounding the system.

Abstract: The instant disclosure is directed to methods for generating stem cell-derived immune cells with enhanced function. Disclosed herein are methods for modifying a stem or progenitor cell capable of differentiating into an immune cell to inhibit the function of at least one gene selected from DGK? and DGK?, and directing differentiation of that stem or progenitor cells towards enhanced immune cells. Also disclosed herein are immune cells or stem cells made by the present methods, as well as the use of immune cells in therapeutic treatment.

Abstract: An immersed membrane cassette has a high tank intensity achieved by one or more of: reduced module to module gap; using structural hollow tubing in at least parts of a frame in place of separate permeate and/or air pipes; and, using vertical permeate port connections. The cassette has a tank intensity over 650 m2/m2. The cassette may be combined with a fine screen. This specification also describes an immersed membrane module having a permeate port and/or connector on the top of a header. The permeate connection between the module and a permeate collection tube may be vertical, i.e. perpendicular to the length of the header. A piston seal may be used between the permeate port of the header and the permeate collection tube. The permeate collection tube may be a horizontal structural member on the periphery of a frame that holds the module.

Abstract: A display processing device includes a display device interface and a processing unit. The processing is configured to transition at least a first component of the display processing system into a low-power state in response to an active region of a first video frame of a plurality of video frames having completed. A second component of the display processing device is configured to maintain a temporal count value corresponding to a current frame line of the plurality of video frames, and further to generate a first signal in response to the temporal count value corresponding to a first trigger value. The first signal causes the at least first component to transition out of the low-power state.

Abstract: A system and method for intent-based active callback management using enhanced callback objects, utilizing a cloud callback system comprising at least a profile manager, callback manager, interaction manager, media server, and environment analyzer, allowing users to call businesses, agents in contact centers, or other users who are connected to a cloud callback system, and, failing to connect to the individual they called, allow for an automatic callback object to be created, whereby the two users may be automatically called and bridged together at a time when both users are available.

Abstract: A retractable fuselage mounted landing gear assembly is disclosed. The landing gear assembly includes a main strut, a drag stay and a landing gear main fitting. A first end of the drag stay is attached to the main strut and a second end of the drag stay is connected to the fuselage. A first end of the landing main fitting is attached to the main strut and a second end of the main fitting is connected to the fuselage. When the landing gear is extended, substantially all the landing gear loads are transferred from the landing gear to the fuselage via one or more of the drag stay and the main fitting.

Abstract: A shell extractor tool for removing a jammed ammunition shell from a firearm comprises a handle portion and a shaft portion. The shaft portion is adapted to be inserted through a firearm port and terminates at a proximal end and wherein the proximal end is angled relative to a remainder of the shaft portion to permit engagement of the jammed ammunition shell in a chamber of a firearm. The handle portion is adapted to be grasped by a user and to apply leverage to the jammed ammunition shell, to allow removal of the ammunition shell from the firearm with the shell extractor tool. The shell extractor tool may be provided with a sheath to provide a shell extractor tool kit. The sheath comprises a first structural portion and a second structural portion. The first structural portion and second structural portion are secured together to form a pocket to receive and reversibly secure the extractor tool. The sheath may optionally comprise a third structural portion.