Abstract: Patient interface components and/or associated head gear and adjustment systems improve sealing and/or patient comfort and/or ease of use. The interface comprising an inflating or ballooning seal. The headgear assembly can be connected to the interface with an elastic component and an inelastic component. The elastic component enabling a course fitting of the interface to the patient and the inelastic component enabling a final fitting of the interface to the patient.

Abstract: A method for determining the presence, absence or amount of two or more target polynucleotides in a sample comprising additional components, the method comprising: (i) contacting the sample with a panel of two or more probes under conditions suitable for hybridisation of the target polynucleotides to the probes, wherein: (a) each probe comprises a non-hybridisation region and a hybridisation region that specifically hybridises to one of the target polynucleotides to form a hybridised probe; and (b) the hybridisation region of a probe of the panel comprises one or more non-natural nucleotides; (ii) contacting the sample prepared in step (i) with a transmembrane pore through which a single stranded polynucleotide but not a double stranded polynucleotide can pass and applying a potential difference to the transmembrane pore such that the hybridised probes in the sample interact with the pore; (iii) measuring current blockades having a duration within a defined window, wherein: (a) the one or more non-natu

Abstract: A dispersion management system for soliton or soliton-like transmission systems comprises a length of optical fibre (L) in which a plurality of sections (l) made up of components (N, A) of opposite sign dispersions are concatenated together. The duration of the dispersion compensation phase is short in comparison with the propagation interval in the remainder of the system and that the path average dispersion is anomalous.

Abstract: A dispersion management system for soliton or soliton-like transmission systems comprises a length of optical fiber (L) in which a plurality of sections (I) made up of components (N,A) of opposite sign dispersions are concatenated together. The duration of the dispersion compensation phase is short in comparison with the propagation interval in the remainder of the system and that the path average dispersion is anomalous.

Abstract: A dispersion management system for soliton or soliton-like transmission systems comprises a length of optical fiber (L) in which a plurality of sections (l) made up of components (N,A) of opposite sign dispersions are concatenated together. The duration of the dispersion compensation phase is short in comparison with the propagation interval in the remainder of the system and that the path average dispersion is anomalous.