Abstract: We describe a touch sensitive holographic image display device for holographically projecting a touch sensitive image at an acute angle onto a surface on which the device is placed. The device includes holographic image projection optics comprising at least one coherent light source illuminating a spatial light modulator (SLM), output optics to project a hologram onto an acute angle surface, and a remote touch sensing system to remotely detect a touch of a location within or adjacent to the holographically displayed image. A control system is configured to provide data defining an image for display, to receive detected touch data, and to control the device responsive to remote detection of a touch of a the displayed image.

Abstract: We describe a touch sensitive holographic image display device for holographically projecting a touch sensitive image at an acute angle onto a surface on which the device is placed. The device includes holographic image projection optics comprising at least one coherent light source illuminating a spatial light modulator (SLM), output optics to project a hologram onto an acute angle surface, and a remote touch sensing system to remotely detect a touch of a location within or adjacent to the holographically displayed image. A control system is configured to provide data defining an image for display, to receive detected touch data, and to control the device responsive to remote detection of a touch of a the displayed image.

Abstract: Embodiments include a hardware accelerator for non-negative matrix factorization (NMF), in particular for driving an OLED display. The hardware accelerator determines a oair of factor matrices (R;C) which when multiplied together approximate a target matrix. Each factor matrix R, C has multiple data buses each associated with a respective block of memory and there is a matrix of processor blocks and an associated memory block storing a portion of a matrix (Q) representing a difference between a product of the pair of factor matrices and the target matrix. Control circuitry controls the reading and writing of data between the various elements to perform the matrix factorisation.

Abstract: A method of driving an electro-optic display, the display having a plurality of pixels each addressable by a row electrode and a column electrode, the method including: receiving image data for display, the image data defining an image matrix; factorizing the image matrix into a product of at least first and second factor matrices, the first factor matrix defining row drive signals for the display, the second factor matrix defining column drive signals for the display; and driving the display row and column electrodes using the row and column drive signals respectively defined by the first and second factor matrices.

Abstract: A mechanism for actuating a poppet valve (28) of an internal combustion engine, comprises two coaxially mounted cams (12,14), cam followers (18,20) in contact with the respective cams (12,14) mounted on a common summation lever (16) which is movable in proportion to the instantaneous sum of the lifts of the two cams (12,14), and a rocker (24) pivotably connected to the summation lever (16) and serving to open the engine valve (28). The rocker is pivotable about a pivot (126) having a fixed preset position and a control spring (134) is provided between the summation lever (16) and a fixed point on the engine to urge the rocker (24) into contact with the tip of the valve (28) and the pivot (126) while the valve is closed.

Abstract: A method for locating a target wireless device is disclosed. At least one directional antenna is swept through a field of view at each of a plurality of sensing locations. A position is determined for each of the plurality of sensing locations. During the sweep at each of the plurality of sensing locations, a set of signal strength data for the target wireless device and a set of bearing information are collected. A plurality of lines of bearing are determined, one from each of the plurality of sensing locations to the target wireless device, based on the determined position, the collected set of signal strength data, and bearing information for each of the plurality of sensing locations. A target location of the target wireless device is determined based on an intersection of at least two lines of bearing from the plurality of lines of bearing.

Abstract: We describe a touch sensitive image display device for projecting a touch sensitive displayed image at an acute angle onto a surface on which the device is placed, the device comprising: a first light source to project a first light distribution; a second light source to project a second light distribution; a touch sensor system to remotely detect touch of an area of said surface within or adjacent to said displayed image by detecting change of said first light distribution, and having an output to provide a detected touch signal; a presence sensor system to remotely detect presence of an object at least partially within said second light distribution by detecting change of said second light distribution, and having an output to provide a detected presence signal; a controller configured to control said device responsive to said detected touch signal and further configured to control said device responsive to said detected presence signal.

Abstract: We describe a touch sensitive image display device for projecting a touch sensitive displayed image at an acute angle onto a surface on which the device is placed. The device comprises: light sources to project two-dimensional first and second light distributions in respective first and second planes; and a multi-pixel sensor system to remotely detect touch of an area of said surface within or adjacent to the displayed image by detecting light from the first distribution to provide a detected touch signal. The multi-pixel sensor system also remotely detects presence of an object within the second light distribution to provide a detected presence signal. The device is configured to multiplex projection of the first light and second distributions. A controller has an input to receive the detected touch and detected presence signals and is configured to control the device responsive to these signals.

Abstract: We describe a touch sensitive holographic image display device for holographically projecting a touch sensitive image at an acute angle onto a surface on which the device is placed. The device includes holographic image projection optics comprising at least one coherent light source illuminating a spatial light modulator (SLM), output optics to project a hologram onto an acute angle surface, and a remote touch sensing system to remotely detect a touch of a location within or adjacent to the holographically displayed image. A control system is configured to provide data defining an image for display, to receive detected touch data, and to control the device responsive to remote detection of a touch of a the displayed image.

Abstract: A method for locating a target wireless device is disclosed. At least one directional antenna is swept through a field of view at each of a plurality of sensing locations. A position is determined for each of the plurality of sensing locations. During the sweep at each of the plurality of sensing locations, a set of signal strength data for the target wireless device and a set of bearing information are collected. A plurality of lines of bearing are determined, one from each of the plurality of sensing locations to the target wireless device, based on the determined position, the collected set of signal strength data, and bearing information for each of the plurality of sensing locations. A target location of the target wireless device is determined based on an intersection of at least two lines of bearing from the plurality of lines of bearing.

Abstract: A method of imaging phenomena that occurs on a surface of a substrate includes contacting a fluid with a top surface of the substrate, and imaging phenomena that occurs on the top surface of the substrate by observing the substrate through polarized light in the absence of a liquid crystal after the liquid has contacted the top surface of the substrate. The top surface of the substrate has an anisotropic topography, and the wavelength of the polarized light is larger than the anisotropic topography of the top surface of the substrate.

Abstract: A mechanism for actuating a poppet valve (28) of an internal combustion engine, comprises two coaxially mounted cams (12,14), cam followers (18,20) in contact with the respective cams (12,14) mounted on a common summation lever (16) which is movable in proportion to the instantaneous sum of the lifts of the two cams (12,14), and a rocker (24) pivotably connected to the summation lever (16) and serving to open the engine valve (28). The rocker is pivotable about a pivot (126) having a fixed preset position and a control spring (134) is provided between the summation lever (16) and a fixed point on the engine to urge the rocker (24) into contact with the tip of the valve (28) and the pivot (126) while the valve is closed.

Abstract: A method for preparing a rubbed substrate structure suitable for use in a liquid crystal assay device, includes reacting a biochemical blocking compound that includes at least one reactive group with an activated modified surface of a support, the activated modified surface of the support having at least one functional group capable of reacting with the reactive group of the biochemical blocking compound, wherein a covalent bond is formed between the biochemical blocking compound and the support producing a support with a surface comprising the biochemical blocking compound. The method also includes rubbing the surface having the biochemical blocking compound to produce a rubbed surface that possesses features that drive uniform anchoring of liquid crystals when the liquid crystals contact the rubbed surface.

Abstract: This invention generally relates to data processing hardware, and more particularly to hardware accelerators and related methods for matrix factorisation especially non-negative matrix factorisation (NMF). Embodiments of the invention are particularly useful for driving electroluminescent displays such as OLED displays.

Abstract: The disclosed modulators of Rb:Raf-1 interactions are potent, selective disruptors of Rb:Raf-1 binding, with IC50 values ranging from 80 nM to 500 nM. Further, these compounds are surprisingly effective in inhibiting a wide variety of cancer cells, including osteosarcoma, epithelial lung carcinoma, non-small cell lung carcinoma, three different pancreatic cancer cell lines, two different glioblastoma cell lines, metastatic breast cancer, melanoma, and prostate cancer. Moreover, the disclosed compounds effectively disrupt angiogenesis and significantly inhibited tumors in nude mice derived from human epithelial lung carcinoma tumors. Accordingly, the disclosed compounds, pharmaceutical compositions comprising the compounds, methods of inhibiting cell proliferation, methods of treating subjects with cancer, and methods of preparing the disclosed compounds are provided.

Abstract: An engine is described having two camshafts 14, 16 each of which carries two groups of cams and comprises an inner shaft coupled for rotation with a first group of cams and an outer tube rotatably supported by the inner shaft and coupled for rotation with the second group of cams. A phaser 12 is provided to enable the phase of at least one of the two groups of cams on one of the SAP camshafts 14, 16 to be varied with reference to the phase of the engine crankshaft. Drive links in the form of meshing gear wheels, drive chains or belts, couple the two corresponding groups of cams on the respective camshafts for rotation in unison with one another.

Abstract: The present invention relates to stilbene and quinine compounds related to combretastatin A-4 and their use as anticancer compounds and prodrugs. The compounds include those with an alkyl group on the double bond of cis or trans-stilbenes, compounds with one or more (and preferably 2 or 3) alkyl group substituents on the stilbene a ring, compounds with an alkoxy group other than methoxy at position 3, 4 and/or 5 of the stilbene A ring, compounds (or prodrugs) in which BOC amino acid esters are formed with the phenolic hydroxyl at the 3-position of the B ring and compounds (or prodrugs) based on a benzoquinone B ring. The present invention further relates to the photochemical reactions of stilbene compounds, either the above compounds disclosed for the first time herein or compounds based on prior art stilbenes.

Abstract: A holographic display has a pixellated (101, 102, 103) hologram display device (100) with a predetermined resolution and a pixellated (121-126) phase mask (120) arranged such that holograms displayed on the SLM (100) are viewed through the phase mask, wherein the phase mask has a resolution higher than the predetermined resolution.

Abstract: This invention relates to methods and apparatus for driving electro-optic, in particular organic light emitting diodes (OLED) displays using multi-line addressing (MLA) techniques Embodiments of the invention are particularly suitable for use with so-called passive matrix OLED displays A method of driving an electro-optic display, the display having a plurality of pixels each addressable by a row electrode and a column electrode, the method comprising receiving image data for display, said image data defining an image matrix, factorising said image matrix into a product of at least first and second factor matrices, said first factor matrix defining row drive signals for said display, said second factor matrix defining column drive signals for said display, and driving said display row and column electrodes using said row and column drive signals respectively defined by said first and second factor matrices

Abstract: A method of forming a liquid crystal device, includes: contacting an aqueous solution comprising a surfactant and a receptor molecule with a top surface of a liquid crystal. The liquid crystal is in a holding compartment of a substrate, and the receptor molecule is adsorbed on the top surface of the liquid crystal forming an interface between the liquid crystal and the aqueous solution. The receptor molecule is different than the surfactant. A method of detecting a compound in a flowing stream includes passing an aqueous solution over a top surface of a liquid crystal in a holding compartment of a substrate. The method also includes determining whether a change in the orientation of the liquid crystal occurs as the aqueous solution is passed over the top surface of the liquid crystal. A change in the orientation of the liquid crystal indicates the presence of the compound in the flowing stream.