Abstract: A flexible container, system and method of manufacture can include an in-line system that allows flexible containers of varying sizes to be manufactured in a single relatively high speed and efficient production line and in a single clean room through the use of transport and exchange equipment configured to adeptly handle flexible containers throughout the process.

Abstract: This embodiment teaches a variation of GCD-based sieving, building tables of prime products, but intentionally restricting the size of table entries to fit within a single machine word. This combination allows one to mix advantages of the two most popular sieves, while retaining the simple and straightforward structure of the simpler one. Divisor length restriction can provide significant savings in the number of long divisions, but may be implemented with only two very specific primitives. The two primitives offer better optimization capabilities than a fully generic multiword arithmetic library.

Abstract: Linking sequence which modulate cross-talk between modules of Type I polyketide synthases have been identified. Thus, arbitrarily chosen modules can be mixed and matched by supplying the appropriate linkers to obtain desired polyketide synthases and new polyketides. The modules are provided suitable linkers so that the polyketide chain is passed from one module to the other in the correct sequence. Synthetic peptides which mimic linkers can be used to inhibit the synthesis of polyketides. Kinetic channeling, both intrapolypeptide and interpolypeptide, of diketide intermediates in a Type I polyketide synthase can occur. In addition, the role of protein-protein interactions between a donor acryl carrier protein (ACP) domain and a downstream ketosynthase (KS) domain and enzyme-substrate interactions in the channeling of intermediates between polyketide synthase modules and between a polyketide synthase module and a NRPS module has been identified.