Patents by Inventor Nicolas Tesson

Nicolas Tesson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210284611
    Abstract: Object of the present invention is a highly stable crystalline form of Eltrombopag (ETP) monoethanolamine salt, named Form D1, having the highest thermodynamically stability with excellent non-hygroscopicity, and particularly well suitable for pharmaceutical purposes, with related process.
    Type: Application
    Filed: July 25, 2019
    Publication date: September 16, 2021
    Applicant: F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A.
    Inventors: Nicolas TESSON, Jordi DE MIER VINUE, Paolo STABILE, Pierluigi PADOVAN, Matteo DE POLI, Angelo RESTELLI
  • Publication number: 20210198211
    Abstract: Object of the present invention is a better crystalline form of Eltrombopag (ETP) monoethanolamine salt, named Form D, stable, suitable for pharmaceutical purposes, and with the highest solubility in water and excellent non-hygroscopicity, then the related process and intermediates thereof.
    Type: Application
    Filed: July 25, 2019
    Publication date: July 1, 2021
    Applicant: F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A.
    Inventors: Nicolas TESSON, Jordi DE MIER VINUE, Paolo STABILE, Pierluigi PADOVAN, Matteo DE POLI, Angelo RESTELLI
  • Publication number: 20200405648
    Abstract: A pharmaceutical composition comprising apomorphine (APO) in a solid crystalline form, wherein the solid crystalline form is an APO·palmitic acid cocrystal solid particle crystalline form.
    Type: Application
    Filed: January 15, 2019
    Publication date: December 31, 2020
    Inventors: Enrique LLAUDET CARLES, Nicolas TESSON, Montserrat TRILLA CASTAÑO
  • Publication number: 20200369586
    Abstract: The present invention relates to cocrystals of 2-[(1R,6R)-6-isopropenyl-3-methylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol and a zwitterion coformer, processes for their preparation, and their use as a medicament and for the purification of 2-[(1R,6R)-6-isopropenyl-3-methylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol. The invention also relates to compositions comprising the cocrystal.
    Type: Application
    Filed: August 6, 2018
    Publication date: November 26, 2020
    Inventors: Alexander Christian COMELY, Nicolas TESSON, Carmen JIMÉNEZ GONZÁLEZ
  • Publication number: 20200331929
    Abstract: The present invention relates to (R)-9-(2,5-difluorophenethyl)-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one salts, to pharmaceutical compositions comprising them, and to their use in therapy and/or prophylaxis of sigma receptor and/or ?-opioid receptor associated disease.
    Type: Application
    Filed: October 16, 2018
    Publication date: October 22, 2020
    Inventors: Carmen ALMANSA-ROSALES, Nicolas TESSON
  • Patent number: 10745373
    Abstract: The present invention relates to a process for preparing fluorescein quinoid form of Formula (I): Furthermore, the present invention relates to a new solid fluorescein form and a process for the preparation thereof. The present invention also relates to the use of said new solid fluorescein form in the synthesis of fluorescein quinoid form.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: August 18, 2020
    Assignee: Delmar Chemicals Inc.
    Inventors: Nicolas Tesson, Eduard Bugan, Nadejda Spassova, Alain Menard
  • Publication number: 20200171055
    Abstract: The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs/coxibs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain.
    Type: Application
    Filed: December 19, 2019
    Publication date: June 4, 2020
    Inventors: Carlos-Ramón PLATA-SALAMAN, Nicolas TESSON
  • Patent number: 10548909
    Abstract: The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs/coxibs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain.
    Type: Grant
    Filed: February 14, 2019
    Date of Patent: February 4, 2020
    Assignee: ESTEVE PHARMACEUTICALS, S.A.
    Inventors: Carlos Ramon Plata Salaman, Nicolas Tesson
  • Publication number: 20190276414
    Abstract: Relating to processes for preparing suvorexant or its pharmaceutically acceptable salts through the formation of a cocrystal of (R)-benzyl 5-methyl-1,4-diazepane-1-carboxylate hydrochloride with (R)-(+)-1,1,2-triphenyl-1,2-ethanediol ((R)-TED). This cocrystal provides the resolution of an intermediate of suvorexant, in particular, of (rac)-benzyl5-methyl-1,4-diazepane-1-carboxy-lateor a hydrochloride salt thereof. It also relates to a new cocrystal useful in such preparation processes.
    Type: Application
    Filed: June 2, 2017
    Publication date: September 12, 2019
    Inventors: Alexander Christian COMELY, Nicolas TESSON
  • Publication number: 20190231800
    Abstract: The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs/coxibs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain.
    Type: Application
    Filed: February 14, 2019
    Publication date: August 1, 2019
    Applicant: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Carlos Ramon PLATA SALAMAN, Nicolas TESSON
  • Patent number: 10245276
    Abstract: The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs/coxibs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain.
    Type: Grant
    Filed: August 9, 2016
    Date of Patent: April 2, 2019
    Assignee: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Carlos Ramon Plata Salaman, Nicolas Tesson
  • Patent number: 10238668
    Abstract: The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs/coxibs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain.
    Type: Grant
    Filed: July 12, 2016
    Date of Patent: March 26, 2019
    Assignee: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Carlos Ramon Plata Salaman, Nicolas Tesson
  • Patent number: 10155740
    Abstract: The present invention relates to novel solid crystal forms of Pomalidomide named Form B, Form M, Pomalidomide:Gentisic acid co-crystal and their preparation. Advantageously, these solid forms are used in pharmaceutical compositions for the treatment and the prevention of multiple myeloma, of inflammatory diseases, of autoimmune diseases, of immune diseases, of myelodysplastic syndrome, of myeloproliferative disorders, of anemia, of scleroderma, amyloidosis or of other diseases associated with unwanted angiogenesis.
    Type: Grant
    Filed: November 24, 2016
    Date of Patent: December 18, 2018
    Assignee: F.I.S.—FABBRICA ITALIANA SINTETICI S.P.A
    Inventors: Alessandro Gagnoni, Antonio Germani, Nicolas Tesson
  • Publication number: 20180344854
    Abstract: The invention relates to a stable supersaturated aqueous solution comprising bilastine and an selected from glutaric acid, citric acid, ?-cetoglutaric acid, tartaric acid, acetic acid, propionic acid and mixtures thereof and to its use in the treatment and/or prevention of conditions mediated by H1 histamine receptor, such as allergic disorders or diseases. The invention also relates to the use of the above organic carboxylic acids to increase the aqueous solubility of bilastine.
    Type: Application
    Filed: November 18, 2016
    Publication date: December 6, 2018
    Inventors: Gonzalo Hernández Herrero, Victor Rubio Royo, Neftalí García Domínguez, Gonzalo Canal Mori, Nicolas Tesson
  • Publication number: 20180319766
    Abstract: The invention relates to a cocrystal comprising a) at least bilastine and, b) at least a cocrystal forming compound selected from the group consisting of glutaric acid, adipic acid, sorbic acid, succinic acid, benzoic acid, 4-aminobenzoic acid, L-malic acid, resorcinol, methyl 4-hydroxy benzoate and N-(4-hydroxyphenyl)acetamide and mixtures thereof, or a solvate thereof. The invention further relates to methods for obtaining said cocrystals and to their use in the treatment and/or prevention of conditions mediated by H1 histamine receptor, such as allergic disorders or diseases. The invention also relates to a method for increase the aqueous solubility of the above compounds of formula (I).
    Type: Application
    Filed: November 18, 2016
    Publication date: November 8, 2018
    Inventors: Gonzalo Hernandez Herrero, Victor Rubio Royo, Neftali Garcia Dominguez, Gonzalo Canal Mori, Carme Jimenez Gonzalez, Jordi De Mier Vinue, Nicolas Tesson
  • Publication number: 20180099944
    Abstract: The present invention relates to novel solid crystal forms of Pomalidomide named Form B, Form M, Pomalidomide:Gentisic acid co-crystal and their preparation. Advantageously, these solid forms are used in pharmaceutical compositions for the treatment and the prevention of multiple myeloma, of inflammatory diseases, of autoimmune diseases, of immune diseases, of myelodysplastic syndrome, of myeloproliferative disorders, of anemia, of scleroderma, amyloidosis or of other diseases associated with unwanted angiogenesis.
    Type: Application
    Filed: November 24, 2016
    Publication date: April 12, 2018
    Inventors: Alessandro GAGNONI, Antonio GERMANI, Nicolas TESSON
  • Publication number: 20170349533
    Abstract: The present invention refers to new solid forms of Enclomiphene citrate and Enclomiphene base, processes for preparing thereof and uses.
    Type: Application
    Filed: May 19, 2017
    Publication date: December 7, 2017
    Inventors: Pierluigi PADOVAN, Lorenzo CARUANA, Nicolas TESSON
  • Patent number: 9822063
    Abstract: The present invention refers to new solid forms of Enclomiphene citrate and Enclomiphene base, processes for preparing thereof and uses.
    Type: Grant
    Filed: October 26, 2015
    Date of Patent: November 21, 2017
    Assignee: F.I.S.—FABBRICA ITALIANA SINTETICI S.P.A
    Inventors: Pierluigi Padovan, Lorenzo Caruana, Nicolas Tesson
  • Patent number: 9738607
    Abstract: The present invention refers to an improved process for the preparation of Sorafenib tosylate ethanol solvate and Sorafenib tosylate form III.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: August 22, 2017
    Assignee: F.I.S.—FABBRICA ITALIANA SINTETICI S.P.A.
    Inventors: Nicolas Tesson, Carmen Jiménez, Llorenç Rafecas, Marta Pontini
  • Publication number: 20170027965
    Abstract: The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs/coxibs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain.
    Type: Application
    Filed: August 9, 2016
    Publication date: February 2, 2017
    Applicant: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Carlos Ramon PLATA SALAMAN, Nicolas TESSON