Patents by Inventor Nicolas Tesson

Nicolas Tesson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the manufacture of ivabradine and of intermediates of synthesis thereof
    Patent number: 9006424
    Abstract: The invention concerns a new process for the resolution of ivabradine and of intermediates of synthesis thereof.
    Type: Grant
    Filed: July 31, 2012
    Date of Patent: April 14, 2015
    Assignee: Laboratorio Chimico Internazionale S.p.A.
    Inventors: Antonio Nardi, Bruno De Angelis, Paolangelo Cerea, Jane Llorenc Rafecas, Nicolas Tesson
  • CRYSTALLINE FORMS OF SAXAGLIPTIN
    Publication number: 20150087686
    Abstract: It comprises a cocrystal of saxagliptin hydrochloride and a compound selected from the group consisting of saxagliptin, glycolic acid, malonic acid, and urea; or a solvate thereof, or a hydrate thereof. It also comprises a salt of saxagliptin with glycolic acid 1:1 hydrate. It also comprises their preparation processes, as well as their use as antidiabetics.
    Type: Application
    Filed: April 24, 2013
    Publication date: March 26, 2015
    Applicant: ENANTIA, S.L.
    Inventors: Nicolas Tesson, Montserrat Trilla Castaño, Lydia Cárdenas Romaña, Llorenç Rafecas Jané
  • PROCESS FOR THE MANUFACTURE OF IVABRADINE AND OF INTERMEDIATES OF SYNTHESIS THEREOF
    Publication number: 20140357859
    Abstract: The invention concerns a new process for the resolution of ivabradine and of intermediates of synthesis thereof.
    Type: Application
    Filed: July 31, 2012
    Publication date: December 4, 2014
    Applicant: LOBORATORIO CHIMICO INTERNAZIONALE S.p.A.
    Inventors: Antonio Nardi, Bruno De Angelis, Paolangelo Cerea, Jane Llorenc Rafecas, Nicolas Tesson
  • CO-CRYSTALS OF TRAMADOL AND NSAIDs
    Publication number: 20140350110
    Abstract: The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain.
    Type: Application
    Filed: July 7, 2014
    Publication date: November 27, 2014
    Applicant: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Helmut Heinrich BUSCHMANN, Lluis SOLA CARANDELL, Jordi BENET BUCHHOLZ, Jordi Carles CERON BERTRAN, Carlos Ramon PLATA SALAMAN, Nicolas TESSON
  • Co-crystal intermediates of rosuvastatin and methods of using same
    Patent number: 8815862
    Abstract: Methods for the preparation of Rosuvastatin by co-crystals of Rosuvastatin or intermediates are provided. Also provided are co-crystals, pharmaceutical compositions which include such co-crystals and methods for treating conditions associated with hypercholesterolemia by administering such compositions.
    Type: Grant
    Filed: December 3, 2012
    Date of Patent: August 26, 2014
    Assignee: F.I.S. Fabbrica Italiana Sintetici S.p.A.
    Inventors: Clark Ferrari, Andrea Castellin, Marco Galvagni, Nicolas Tesson, Jordi De Mier, Llorenç Rafecas
  • CO-CRYSTALS OF TRAMADOL AND COXIBS
    Publication number: 20140057879
    Abstract: The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs/coxibs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain.
    Type: Application
    Filed: October 29, 2013
    Publication date: February 27, 2014
    Applicant: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Carlos Ramon PLATA SALAMAN, Nicolas TESSON
  • Co-crystals of tramadol and coxibs
    Patent number: 8598152
    Abstract: The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs/coxibs, processes for preparation of the same and their uses in pharmaceutical formulations for the treatment of pain.
    Type: Grant
    Filed: April 19, 2010
    Date of Patent: December 3, 2013
    Assignee: Laboratorios Del Dr. Esteve, S.A.
    Inventors: Carlos Ramon Plata Salaman, Nicolas Tesson
  • CO-CRYSTALS OF VENLAFAXINE AND CELECOXIB
    Publication number: 20130028937
    Abstract: The present invention relates to a co-crystal of celecoxib and venlafaxine, processes for preparation of the same and its use as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain, including chronic pain; or of depression in patients which suffer from chronic pain and/or chronic inflammation or in patients with a chronic musculo-skeletal inflammatory illness, with the inflammatory illness preferably being selected from osteoarthritis or rheumatoid arthritis.
    Type: Application
    Filed: December 23, 2010
    Publication date: January 31, 2013
    Applicant: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Carlos Ramon Plata Salaman, Sebastia Videla Ces, Nicolas Tesson, Montserrat Trilla Castano
  • CO-CRYSTALS OF TRAMADOL AND COXIBS
    Publication number: 20120172398
    Abstract: The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs/coxibs, processes for preparation of the same and their uses in pharmaceutical formulations for the treatment of pain.
    Type: Application
    Filed: April 19, 2010
    Publication date: July 5, 2012
    Applicant: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Carlos Ramon Plata Salaman, Nicolas Tesson
  • Preparation of delmopinol
    Patent number: 8093398
    Abstract: It comprises a process for the production of delmopinol or a pharmaceutically acceptable salt and/or a solvate thereof, by subjecting the compound of formula (II) where R1 and R2 are the same or different, independently selected from the group consisting of H, (C1-C6) alkyl or, alternatively, R1 and R2 form, together with the carbon atom to which they are attached, a (C5-C6) cycloalkyl radical; and R3 is a radical selected from the group consisting of CF3, (C1-C4) alkyl, phenyl, and phenyl mono- or disubstituted by a radical selected from the group consisting of (C1-C4)-alkyl, halogen and nitro to a deprotection and cyclisation reaction. The process is useful to prepare delmopinol or its salts on an industrial scale. The compound of formula (II) is new and also forms part of the present invention, as well as its preparation process and other new intermediates of said preparation process.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: January 10, 2012
    Assignee: Sinclair Pharmaceticals Limited
    Inventors: Alexander Comely, Llorenç Rafecas Jane, Nicolas Tesson, Antoni Riera Escale
  • CO-CRYSTALS OF TRAMADOL AND NSAIDs
    Publication number: 20110257134
    Abstract: The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs, processes for preparation of the same, their uses in pharmaceutical formulations, and for the treatment of various disorders, including pain.
    Type: Application
    Filed: October 16, 2009
    Publication date: October 20, 2011
    Applicant: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Helmut Heinrich Buschmann, Lluis Sola Carandell, Jordi Benet Buchholz, Jordi Carles Ceron Bertran, Carlos Ramon Plata Salaman, Nicolas Tesson
  • SALTS OF MEMANTINE AND COX-INHIBITORS AND THEIR CRYSTAL FORM IN THE TREATMENT OF PAIN
    Publication number: 20110105443
    Abstract: The present invention relates to salts of Memantine and COX-INHIBITORs, their crystal form, the processes for preparation of the same and their uses for the treatment of various disorders, including pain.
    Type: Application
    Filed: March 6, 2009
    Publication date: May 5, 2011
    Applicant: LABORATORIES DEL DR. ESTEVE, S.A.
    Inventors: Helmut Heinrich Buschmann, Nicolas Tesson, Joan Farran, Llorenc Rafecas
  • Preparation of Delmopinol
    Publication number: 20110082301
    Abstract: It comprises a process for the production of delmopinol or a pharmaceutically acceptable salt and/or a solvate thereof, by subjecting the compound of formula (II) where R1 and R2 are the same or different, independently selected from the group consisting of H, (C1-C6) alkyl or, alternatively, R1 and R2 form, together with the carbon atom to which they are attached, a (C5-C6) cycloalkyl radical; and R3 is a radical selected from the group consisting of CF3, (C1-C4) alkyl, phenyl, and phenyl mono- or disubstituted by a radical selected from the group consisting of (C1-C4)-alkyl, halogen and nitro to a deprotection and cyclisation reaction. The process is useful to prepare delmopinol or its salts on an industrial scale. The compound of formula (II) is new and also forms part of the present invention, as well as its preparation process and other new intermediates of said preparation process.
    Type: Application
    Filed: December 20, 2010
    Publication date: April 7, 2011
    Inventors: Alexander Comely, Llorenç Rafecas Jane, Nicolas Tesson, Antoni Riera Escale
  • Preparation of delmopinol
    Patent number: 7893258
    Abstract: It comprises a preparation process of delmopinol or a pharmaceutically acceptable salt and/or a solvate thereof, by submitting the compound of formula (II) where R1 and R2 are the same or different, independently selected from the group consisting of H, (C1-C6)-alkyl or, alternatively, R1 and R2 form, together with the carbon atom to which they are attached, a (C5-C6)-cycloalkyl radical; and R3 is a radical selected from the group consisting of CF3, (C1-C4)-alkyl, phenyl, and phenyl mono- or disubstituted by a radical selected from the group consisting of (C1-C4)-alkyl, halogen and nitro to a deprotection and cyclisation reaction. The process is useful to prepare delmopinol or its salts on an industrial scale. The compound of formula (II) is new and also forms part of the present invention, as well as its preparation process and other new intermediates of said preparation process.
    Type: Grant
    Filed: January 10, 2007
    Date of Patent: February 22, 2011
    Assignee: Sinclair Pharmaceuticals Limited
    Inventors: Alexander Comely, Llorenç Rafecas Jane, Nicolas Tesson, Antoni Riera Escale
  • Preparation of Delmopinol
    Publication number: 20090036677
    Abstract: It comprises a preparation process of delmopinol or a pharmaceutically acceptable salt and/or a solvate thereof, by submitting the compound of formula (II) where R1 and R2 are the same or different, independently selected from the group consisting of H, (C1-C6)-alkyl or, alternatively, R1 and R2 form, together with the carbon atom to which they are attached, a (C5-C6)-cycloalkyl radical; and R3 is a radical selected from the group consisting of CF3, (C1-C4)-alkyl, phenyl, and phenyl mono- or disubstituted by a radical selected from the group consisting of (C1-C4)-alkyl, halogen and nitro to a deprotection and cyclisation reaction. The process is useful to prepare delmopinol or its salts on an industrial scale. The compound of formula (II) is new and also forms part of the present invention, as well as its preparation process and other new intermediates of said preparation process.
    Type: Application
    Filed: January 10, 2007
    Publication date: February 5, 2009
    Inventors: Alexander Comely, Llorenc Rafecas Jane, Nicolas Tesson, Atoni Riera Escale