Abstract: A glass-ceramic includes greater than or equal to 55 wt % to less than or equal to 75 wt % SiO2; greater than or equal to 2 wt % to less than or equal to 10 wt % Al2O3; greater than or equal to 8 wt % to less than or equal to 15 wt % Li2O; greater than or equal to 2 wt % to less than or equal to 4 wt % P2O5; greater than or equal to 0.05 wt % and less than or equal to 4.0 wt % CaO; greater than or equal to 5 wt % to less than or equal to 15 wt % ZrO2; and a phase assemblage comprising a crystalline phase and a glass phase, wherein: a ratio of Li2O to Al2O3 is greater than 2 and less than or equal to 4; and a ratio of Li2O to ZrO2 is greater than or equal to 1.2 and less than or equal to 1.7.

Abstract: Described are systems and methods for measuring the similarity of security alerts, security incidents, or other complex data structures at scale using machine-learned signature vectors suitable for efficient similarity-based filtering in conjunction with hashes of the security alerts for more detailed comparisons. In some embodiments, similarity measurements between security incidents are used to base the processing of a current security incident on similar prior security incidents.

Abstract: Provided herein are adeno-associated virus (AAV) compositions for correcting a mutation in a beta globin gene (HBB) gene and methods of using the same to correct an HBB gene mutation in a cell. Also provided are packaging systems for making the adeno-associated virus compositions.

Abstract: A method comprises determining a first and second portion of a quantum circuit specification based at least in part on two or more estimated gate simulation times associated with simulating two or more quantum gate operations; generating a first set of output quantum states (OQSs) by simulating the first portion using a classical processor; determining a first set of measurement results associated with the first set of OQSs; generating a second set of OQSs by simulating or executing the second portion; determining a second set of measurement results associated with the second set of OQSs; and determining a result based at least in part on the first set of measurement results and the second set of measurement results; where the first set of OQSs and the second set of OQSs do not depend on each other.

Abstract: What are described are compounds of the general formula (I) and agrochemically acceptable salts thereof and their preparation and their use in the crop protection sector.

Abstract: A device for delivering a flowing media is provided. For example, a device for delivering a flowing media may include a housing defining an opening, a first printed circuit board assembly (PCBA), a fluid-resistant seal occluding the opening, and a sensor module. The sensor module comprises a second PCBA having a plurality of electrical contact pads; a sensing element in electrical communication with one or more of the electrical contact pads; and a flow tube at least partially defining a flow path for conveying a flowing media therethrough. The flow tube comprises an elongated main body disposed proximate the first major surface of the second PCBA such that the flow path is disposed proximate the sensing element such that at least a portion of the flowing media makes direct contact with the sensing element. The sensor module is selectively mechanically and electrically attachable to the device.

Abstract: A natural cleaning product which does not contain any harsh chemicals or toxins. Specifically, the cleaning product is based on borax and yucca plant products. A composition for an organic cleaning product comprises distilled water; borax; distilled white vinegar; yucca root soap; and optionally, lavender essential oil, peppermint essential oil; and eucalyptus. Also disclosed is a process for the production of yucca root soap which is used in producing the organic cleaning product of the invention.

Abstract: A method of making a biocompatible composition for sealing tissue includes mixing a first fluid having a first reactive component (e.g., an electrophile) and a second fluid having a second reactive component (e.g., a nucleophile) to form a mixture and expressing the mixture. During expression, a pH modifying fluid (e.g., NaOH) is added to the mixture at a rate that changes. In one embodiment, a higher ratio of the pH modifying fluid is added to the mixture during a first expressing stage and a lower ratio of said pH modifying fluid is added to the mixture during a second expressing stage. During the first expressing stage, a mixing ratio of the pH modifying fluid, the first fluid and the second fluid is 0.7-1.4:1:1. During the second expressing stage, the mixing ratio of the pH modifying fluid, the first fluid and the second fluid is 0.12-0.24:1:1.

Abstract: The present disclosure relates to a method for preparing a haemostatic composition comprising thrombin, the method comprising the step of reconstituting a dry thrombin directly in a paste, such as a paste comprising a biocompatible polymer. The haemostatic composition comprising thrombin may be prepared from a dry thrombin composition and a paste in a single step operation and be used for treatment of a wound.

Abstract: The present disclosure relates to a method for preparing a haemostatic composition comprising thrombin, the method comprising the step of reconstituting a dry thrombin directly in a paste, such as a paste comprising a biocompatible polymer. The haemostatic composition comprising thrombin may be prepared from a dry thrombin composition and a paste in a single step operation and be used for treatment of a wound.

Abstract: A ventilation system for an appliance that generates an exhaust fluid when used. The appliance being provided within an interior of environment. The ventilation system being fluidly coupled to a ventilator operably coupled to the environment. The ventilation system can include a suction source in fluid communication with the appliance and the exhaust fluid, and a duct fluidly coupling the suction source to the ventilator.

Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein R1a, R1b, R1c, R1d, R2, R2a, and A are as defined herein, including stereoisomers, esters, solvates and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.

Abstract: Disclosed is a high-penetration hot melt adhesive for separation apparatus, such as thin film composite reverse osmosis filtration membranes. Also disclosed is a method of using these hot melt adhesives to bond these membranes to one or more other components of a separation apparatus.

Abstract: The present invention relates to novel herbicidally active, substituted 1,5-diphenylpyrazolyl-3-oxyalkyl acids and 1-phenyl-5-thienylpyrazolyl-3-oxyalkyl acids and derivatives thereof according to the general formula (I) or agrochemically acceptable salts thereof, to processes for preparation thereof and to the use thereof for control of broadleaved weeds and weed grasses in crops of useful plants and for general control of broadleaved weeds and weed grasses in areas of the environment where plant growth is troublesome. The derivatives of the 1,5-diphenylpyrazolyl-3-oxyalkyl acids and 1-phenyl-5-thienylpyrazolyl-3-oxyalkyl acids especially include the esters, salts and amides thereof.

Abstract: A medical device for making foam includes a syringe having a plunger for dispensing a liquid from a liquid dispensing port, and a mixing chamber including a mixing chamber inlet, a mixing chamber outlet, a liquid flow channel extending between the mixing chamber inlet and the mixing chamber outlet, and a gas inlet channel that intersects with the liquid flow channel. The system has a gas cartridge containing the gas, a first gas conduit connected with the syringe, and a second gas conduit connected with the gas inlet channel. An actuator is coupled with the gas cartridge for releasing the gas into the first and second gas conduits. The released gas in the first gas conduit forces the plunger toward the liquid dispensing port for dispensing the liquid from the liquid dispensing port and into the liquid flow channel while the released gas in the second gas conduit flows into the gas inlet channel of the mixing chamber for mixing with the liquid in the liquid flow channel.

Abstract: What are described are compounds of the general formula (I) and agrochemically acceptable salts thereof and their preparation and their use in the crop protection sector.

Abstract: A natural cleaning product which does not contain any harsh chemicals or toxins. Specifically, the cleaning product is based on borax and yucca plant products. A composition for an organic cleaning product comprises distilled water; borax; distilled white vinegar; yucca root soap; and optionally, lavender essential oil, peppermint essential oil; and eucalyptus. Also disclosed is a process for the production of yucca root soap which is used in producing the organic cleaning product of the invention.

Abstract: An adapter device for use with a toilet includes a base member and an attachment member on either end of the base member. The base member is an elongate member that is to extend across diametrically opposed sides of a toilet seat. The attachment members on either end of the base member include two fins that extend downward relative to the base member. The fins are to slidably engage around the sides of the toilet seat and thus prevent lateral movement of the attachment member and base member when the adapter device is placed on top of a toilet seat. The base member and the attachment member are to be positioned on the toilet seat so as to provide support to a perineum of a user.

Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein R1a, R1b, R1c, R1d, R2, R2a, and A are as defined herein, including stereoisomers, esters, solvates and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.