Patents by Inventor Nikolaos Loupis

Nikolaos Loupis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11141482
    Abstract: The present document describes methods of use of photo activated compositions for oral disinfection and/or treatments which comprise at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmacologically acceptable carrier.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: October 12, 2021
    Assignee: KLOX TECHNOLOGIES INC.
    Inventors: Remigio Piergallini, Nikolaos Loupis
  • Patent number: 11135146
    Abstract: The present disclosure provides biophotonic topical compositions, kits and their uses. In some aspects, the biophotonic topical compositions of the present disclosure comprise a first chromophore, a salt selected from one or more bicarbonate or carbonate salts or a combination of the foregoing salts, and one or more gelling agents. In some aspects, the biophotonic topical compositions of the present disclosure comprise a first chromophore, one or more polyols, and one or more gelling agents. The biophotonic compositions of the present disclosure do not include an oxidant selected from the group consisting of a peroxide, a peroxy acid, hydrogen peroxide, carbamide peroxide, an alkali metal peroxide, an alkali metal percarbonate, peroxyacetic acid, and an alkali metal perborate. The biophotonic compositions are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various skin disorders.
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: October 5, 2021
    Assignee: KLOX TECHNOLOGIES LIMITED
    Inventors: Francesco Bellini, David Ohayon, Remigio Piergallini, Nikolaos Loupis, William Curtis
  • Publication number: 20210283417
    Abstract: A method for reversing or mitigating skin aging comprising topically applying a composition which comprises at least one oxidant, and at least one fluorescent dye capable of activating the oxidant and illuminating said composition for a time sufficient to activate the at least one oxidant.
    Type: Application
    Filed: May 28, 2021
    Publication date: September 16, 2021
    Inventors: Remigio PIERGALLINI, Nikolaos LOUPIS, Francesco BELLINI
  • Patent number: 11116841
    Abstract: The present disclosure provides biophotonic topical compositions, kits and their uses. In particular, the biophotonic compositions of the present disclosure are substantially resistant to leaching such that very low amounts of chromophore(s) present in the biophotonic composition leach out of the composition. The biophotonic compositions and their uses are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various skin disorders.
    Type: Grant
    Filed: April 19, 2013
    Date of Patent: September 14, 2021
    Assignee: KLOX TECHNOLOGIES INC.
    Inventors: Nikolaos Loupis, Remigio Piergallini, Shipra Rastogi
  • Publication number: 20210228720
    Abstract: The present technology generally relates to an absorbent biophotonic fiber system and to articles comprising the absorbent biophotonic fiber system as well as to the potential uses thereof, such as, for example, in wound treatment.
    Type: Application
    Filed: June 5, 2019
    Publication date: July 29, 2021
    Inventors: David OHAYON, Carlo BELLINI, Jason GUGLIUZZA, Nikolaos LOUPIS, Remigio PIERGALLINI, Abdellatif CHENITE
  • Publication number: 20210177969
    Abstract: The present disclosure provides biophotonic compositions, kits and their uses. In particular, the biophotonic compositions of the present disclosure arc substantially resistant to leaching such that low amounts of chromophores present in the biophotonic composition leach out of the composition. The biophotonic compositions and their uses are useful for promoting repair of non-healing wounds.
    Type: Application
    Filed: December 22, 2020
    Publication date: June 17, 2021
    Inventors: Nikolaos LOUPIS, Remigio PIERGALLINI, Shipra RASTOGI
  • Publication number: 20210170027
    Abstract: The technology defined in the present document generally relates to a method for enhancing hair growth on an area of a skin of a subject. The method comprises topically applying a composition comprising at least one light-absorbing molecule to the skin; and exposing said applied composition to actinic light to cause activation of the composition. Activation of the applied composition triggers enhancement of hair growth on the skin.
    Type: Application
    Filed: November 16, 2018
    Publication date: June 10, 2021
    Inventors: Giacomo ROSSI, Remigio PIERGALLINI, Nikolaos LOUPIS, Angela PALUMBO PICCIONELLO, Francesco BELLINI, Silvia SCARPONA
  • Patent number: 11020609
    Abstract: There is provided a method for treating pigmented lesions comprising a composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant. The composition may further comprise at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: November 25, 2019
    Date of Patent: June 1, 2021
    Assignee: KLOX TECHNOLOGIES INC.
    Inventors: Remigio Piergallini, Nikolaos Loupis, Francesco Bellini
  • Patent number: 10881736
    Abstract: The present disclosure provides biophotonic compositions, kits and their uses. In particular, the biophotonic compositions of the present disclosure are substantially resistant to leaching such that low amounts of chromophores present in the biophotonic composition leach out of the composition. The biophotonic compositions and their uses are useful for promoting repair of non-healing wounds.
    Type: Grant
    Filed: July 2, 2014
    Date of Patent: January 5, 2021
    Assignee: KLOX TECHNOLOGIES INC.
    Inventors: Nikolaos Loupis, Remigio Piergallini, Shipra Rastogi
  • Publication number: 20200405858
    Abstract: The present disclosure generally relates to methods and processes for modulating biophotonic regimens as well as to the modulated biophotonic regimens resulting therefrom. The present disclosure also generally relates to biophotonic methods for stimulating energy production in a tissue.
    Type: Application
    Filed: November 16, 2018
    Publication date: December 31, 2020
    Inventors: Giacomo ROSSI, Remigio PIERGALLINI, Nikolaos LOUPIS, Angela PALUMBO PICCIONELLO, Andrea MARCHEGIANI, Andrea SPATERNA, Alberto SALVAGGIO, David OHAYON
  • Publication number: 20200390719
    Abstract: The present technology generally provides biophotonic silicone membranes and methods useful in the management of scars. In particular, the biophotonic silicone membranes of the present technology are useful in preventing and/or treating post-surgical scar formation.
    Type: Application
    Filed: August 28, 2018
    Publication date: December 17, 2020
    Applicant: Klox Technologies Inc.
    Inventors: Abdellatif CHENITE, Stephane FAUVERGHE, Nikolaos LOUPIS, Remigio PIERGALLINI
  • Publication number: 20200376121
    Abstract: The present document describes methods and uses of compositions which comprise at least one photoactivator or chromophore in association with a pharmacologically acceptable carrier for use in reducing pain that is associated with a medical condition in a subject.
    Type: Application
    Filed: September 22, 2017
    Publication date: December 3, 2020
    Inventors: Andreas NIKOLIS, Marco ROMANELLI, Nikolaos LOUPIS, Remigio PIERGALLINI, Valentina DINI
  • Publication number: 20200330783
    Abstract: There is provided a method for treating rosacea comprising a composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmaceutically acceptable carrier.
    Type: Application
    Filed: November 25, 2019
    Publication date: October 22, 2020
    Inventors: Remigio PIERGALLINI, Nikolaos LOUPIS, Francesco BELLINI
  • Patent number: 10758744
    Abstract: There is provided a wound healing composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin in association with a pharmaceutically acceptable carrier. In addition, a method of topically treating wounds using at least one oxidant and at least one photoactivator capable of activating the oxidant followed by illumination of said photosensitizer is disclosed.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: September 1, 2020
    Assignee: KLOX TECHNOLOGIES INC.
    Inventors: Remigio Piergallini, Nikolaos Loupis, Francesco Bellini
  • Publication number: 20200230101
    Abstract: The present disclosure describes methods and uses of biophotonic compositions which comprise at least one oxidant and at least one chromophore capable of activating the oxidant, in association with a pharmacologically acceptable carrier for the treatment of otitis externa.
    Type: Application
    Filed: April 6, 2020
    Publication date: July 23, 2020
    Inventors: Francesco BELLINI, Matteo CERQUETELLA, Adolfo Maria TAMBELLA, Andrea SPATERNA, Nikolaos LOUPIS, David OHAYON, Remigio PIERGALLINI
  • Publication number: 20200222537
    Abstract: The present disclosure provides biophotonic compositions comprising one or more photosynthetic organism-derived chromophores or a non-photosynthetic prokaryote-derived chromophores and methods useful in phototherapy. In particular, the biophotonic compositions and the methods of the present disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various other skin disorders.
    Type: Application
    Filed: May 23, 2017
    Publication date: July 16, 2020
    Inventors: Nikolaos LOUPIS, Remigio PIERGALLINI
  • Publication number: 20200222536
    Abstract: The present disclosure provides biophotonic compositions comprising one or more fungal-derived chromophores and methods useful in phototherapy. In particular, the biophotonic compositions and the methods of the present disclosure are useful for the treatment of rare diseases that afflict skin or soft tissues. The present disclosure also provides a photoactivatable fabric composition in combination with the biophotonic compositions.
    Type: Application
    Filed: May 23, 2017
    Publication date: July 16, 2020
    Inventors: Francesco BELLINI, Nikolaos LOUPIS, Remigio PIERGALLINI, Andreas NIKOLIS, Giovanni SCAPAGNINI
  • Patent number: 10687926
    Abstract: The present disclosure relates to a phototherapy device that can deliver light to tissues to activate photoactive agents that have been applied to the tissues or that are included within a fiber optic tip member of the device which may be coupled to a light source using a sleeve. The present disclosure also relates to methods of phototherapy using the phototherapy device such as anti-bactericidal treatment, anti-fungal treatment, anti-parasitic treatment, anti-viral treatment.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: June 23, 2020
    Assignee: KLOX TECHNOLOGIES INC.
    Inventors: Remigio Piergallini, Nikolaos Loupis, Lise Hébert
  • Publication number: 20200147214
    Abstract: The present disclosure generally relates to photo-biomodulation composition comprising a tissue filler and to methods for achieving photo-biomodulation. Specifically, but not exclusively, the present disclosure relates to photo-biomodulation compositions which can be injected into a tissue for achieving photo-biomodulation.
    Type: Application
    Filed: July 18, 2018
    Publication date: May 14, 2020
    Inventors: Andreas NIKOLIS, Nikolaos LOUPIS, Remigio PIERGALLINI
  • Publication number: 20200138949
    Abstract: The present document describes methods of use of photo activated compositions for oral disinfection and/or treatments which comprise at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmacologically acceptable carrier.
    Type: Application
    Filed: November 8, 2019
    Publication date: May 7, 2020
    Inventors: Remigio PIERGALLINI, Nikolaos LOUPIS