Patents by Inventor Nikolaos Loupis

Nikolaos Loupis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170143989
    Abstract: There is provided a wound healing composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin in association with a pharmaceutically acceptable carrier. In addition, a method of topically treating wounds using at least one oxidant and at least one photoactivator capable of activating the oxidant followed by illumination of said photosensitizer is disclosed.
    Type: Application
    Filed: February 7, 2017
    Publication date: May 25, 2017
    Inventors: Remigio Piergallini, Nikolaos Loupis, Francesco Bellini
  • Patent number: 9655829
    Abstract: Disclosed herein are teeth whitening compositions generally including an oxidizing agent, and an activating agent that has an emission wavelength between about 400 nm and about 570 nm. Methods of employing these compositions to whiten teeth, methods of making these compositions and kits that include some or part of the composition ingredients, are also described.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: May 23, 2017
    Assignee: VALEANT PHARMACEUTICALS INTERNATIONAL, INC.
    Inventors: Nikolaos Loupis, Remigio Piergallini
  • Publication number: 20170112755
    Abstract: The present disclosure provides thermosetting biophotonic compositions and methods useful in phototherapy. In particular, the thermosetting biophotonic compositions of the present disclosure include block copolymer and at least one chromophore solubilized in the block copolymer. The thermosetting biophotonic compositions and the methods of the present disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various other skin disorders.
    Type: Application
    Filed: June 9, 2015
    Publication date: April 27, 2017
    Inventors: Remigio Piergallini, Nikolaos Loupis, Emmanuelle Devemy, Éric DesRosiers, Abdellatif Chenite
  • Publication number: 20170106013
    Abstract: The present disclosure provides biophotonic hydrogels and methods useful in phototherapy. In particular, the biophotonic hydrogels of the present disclosure include N-Hydroxyethyl acrylamide (HEAA), and at least one chromophore, wherein the at least one chromophore is not fully photobleached after photopolymerization. The biophotonic hydrogels and the methods of the present disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various other skin disorders.
    Type: Application
    Filed: June 4, 2015
    Publication date: April 20, 2017
    Inventors: Remigio Piergallini, Nikolaos Loupis, Joanna Jaworska, Emmanuelle Devemy, Éric DesRosiers, Abdellatif Chenite
  • Patent number: 9603929
    Abstract: The present document describes methods of use of photo activated compositions for oral disinfection and/or treatments which comprise at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmacologically acceptable carrier.
    Type: Grant
    Filed: November 12, 2014
    Date of Patent: March 28, 2017
    Assignee: KLOX Technologies Inc.
    Inventors: Remigio Piergallini, Nikolaos Loupis
  • Patent number: 9597349
    Abstract: There is provided a wound healing composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin in association with a pharmaceutically acceptable carrier. In addition, a method of topically treating wounds using at least one oxidant and at least one photoactivator capable of activating the oxidant followed by illumination of said photosensitizer is disclosed.
    Type: Grant
    Filed: November 11, 2014
    Date of Patent: March 21, 2017
    Assignee: KLOX Technologies Inc.
    Inventors: Remigio Piergallini, Nikolaos Loupis, Francesco Bellini
  • Publication number: 20170049802
    Abstract: There is provided a method for treating rosacea comprising a composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmaceutically acceptable carrier.
    Type: Application
    Filed: May 24, 2016
    Publication date: February 23, 2017
    Inventors: Remigio Piergallini, Nikolaos Loupis, Francesco Bellini
  • Publication number: 20170027833
    Abstract: The present disclosure provides biophotonic topical compositions and methods useful in phototherapy. In particular, the biophotonic topical compositions of the present disclosure are substantially resistant to leaching such that very low amounts of chromophore(s) present in the biophotonic composition leach out of the composition. The biophotonic compositions and the methods of the present disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various skin disorders.
    Type: Application
    Filed: July 1, 2016
    Publication date: February 2, 2017
    Inventors: Remigio Piergallini, Nikolaos Loupis, Shipra Rastogi
  • Publication number: 20160296444
    Abstract: Disclosed herein are compositions that can rapidly evolve oxygen and/or activated oxygen generally including an oxidizing agent (e.g., a peroxide) and an activating agent that has an emission wavelength between about 400 nm and about 570 nm (e.g., Eosin B, Eosin Y, or Erythrosine B). Methods of employing these compositions to whiten teeth, and methods of making these compositions and kits that include some or part of the composition ingredients, are also described.
    Type: Application
    Filed: April 20, 2016
    Publication date: October 13, 2016
    Inventors: Remigio Piergallini, Nikolaos Loupis
  • Publication number: 20160193338
    Abstract: The present disclosure provides biophotonic compositions, kits and their uses. In particular, the biophotonic compositions of the present disclosure are substantially resistant to leaching such that low amounts of chromophores present in the biophotonic composition leach out of the composition. The biophotonic compositions and their uses are useful for promoting repair of non-healing wounds.
    Type: Application
    Filed: July 2, 2014
    Publication date: July 7, 2016
    Inventors: Nikolaos Loupis, Remigio Piergallini, Shipra Rastogi
  • Patent number: 9375446
    Abstract: There is provided a skin rejuvenation composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: June 28, 2016
    Assignee: KLOX Technologies Inc.
    Inventors: Remigio Piergallini, Nikolaos Loupis, Francesco Bellini
  • Patent number: 9345648
    Abstract: Disclosed herein are compositions that can rapidly evolve oxygen and/or activated oxygen generally including an oxidizing agent (e.g., a peroxide) and an activating agent that has an emission wavelength between about 400 nm and about 570 nm (e.g., Eosin B, Eosin Y, or Erythrosine B). Methods of employing these compositions to whiten teeth, and methods of making these compositions and kits that include some or part of the composition ingredients, are also described.
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: May 24, 2016
    Assignee: KLOX Technologies Inc.
    Inventors: Remigio Piergallini, Nikolaos Loupis
  • Publication number: 20160136075
    Abstract: Disclosed herein are teeth whitening compositions generally including an oxidizing agent, and an activating agent that has an emission wavelength between about 400 nm and about 570 nm. Methods of employing these compositions to whiten teeth, methods of making these compositions and kits that include some or part of the composition ingredients, are also described.
    Type: Application
    Filed: January 26, 2016
    Publication date: May 19, 2016
    Inventors: Nikolaos LOUPIS, Remigio PIERGALLINI
  • Publication number: 20160030564
    Abstract: The present disclosure provides topical biophotonic materials and methods useful in phototherapy. In particular, the topical biophotonic materials of the present disclosure include a cohesive matrix, and at least chromophore which can absorb and emit light from within the topical biphotonic material, wherein the topical biophotonic material is elastic. The topical biophotonic materials and the methods of the present disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various other skin disorders.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Inventors: Nikolaos Loupis, Remigio Piergallini, Éric DesRosiers
  • Publication number: 20160016001
    Abstract: Disclosed herein are devices, systems, and methods for providing light therapy to a subject's tissues. The devices, systems, and methods include a phototherapeutic lamp comprising light generating sources that emit light capable of causing a medical and/or cosmetic treatment of tissues. Also included are uses of the devices. The devices and methods may also include a photoactivatable composition.
    Type: Application
    Filed: February 28, 2014
    Publication date: January 21, 2016
    Inventors: Nikolaos Loupis, Remigio Piergallini
  • Publication number: 20150360047
    Abstract: The present disclosure provides cosmetic compositions and methods for using the cosmetic compositions. In particular, the cosmetic compositions of the present disclosure include one or more chromophore(s) in association with a dermatologically acceptable carrier. The cosmetic biophotonic compositions and the methods of the present disclosure are useful for skin rejuvenation and/or skin conditioning.
    Type: Application
    Filed: September 13, 2013
    Publication date: December 17, 2015
    Applicant: KLOX Technologies Inc.
    Inventors: Nikolaos Loupis, Remigio Piergallini, Lise Hébert
  • Publication number: 20150335904
    Abstract: The present disclosure relates to phototherapy device members which can be coupled to a light source to deliver light to hard to reach or internalized sites and which include a flexible fiber optic tip member having a core for transmitting light and an elastic tubular connector sleeve for mechanically coupling the flexible tip member to the light source. The present disclosure also relates to phototherapy devices which comprise the light source and the flexible fiber optic tip member. The present disclosure also relates to methods of phototherapy using the phototherapy device such as anti-bactericidal treatment, periodontal treatment, wound healing treatment, anti-fungal treatment, anti-parasitic treatment, anti-viral treatment, skin condition treatment, or treatments to minimize or reduce scarring.
    Type: Application
    Filed: May 29, 2013
    Publication date: November 26, 2015
    Inventors: Nikolaos Loupis, Remigio Piergallini, Lise Hébert
  • Publication number: 20150306131
    Abstract: There is provided a skin rejuvenation composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmaceutically acceptable carrier.
    Type: Application
    Filed: November 13, 2014
    Publication date: October 29, 2015
    Inventors: Remigio Piergallini, Nikolaos Loupis, Francesco Bellini
  • Publication number: 20150290320
    Abstract: The present document describes methods of use of photo activated compositions for oral disinfection and/or treatments which comprise at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmacologically acceptable carrier.
    Type: Application
    Filed: November 12, 2014
    Publication date: October 15, 2015
    Inventors: Remigio Piergallini, Nikolaos Loupis
  • Publication number: 20150290103
    Abstract: Disclosed herein are teeth whitening compositions generally including an oxidizing agent (e.g., a peroxide), and an activating agent that has an emission wavelength between about 400 nm and about 570 nm (e.g., Eosin B). Methods of employing these compositions to whiten teeth, methods of making these compositions and kits that include some or part of the composition ingredients, arc also described.
    Type: Application
    Filed: November 14, 2014
    Publication date: October 15, 2015
    Inventors: Remigio Piergallini, Nikolaos Loupis