Patents by Inventor Ning Li
Ning Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260193859Abstract: An auxiliary device and method for recovering forepoling grouted steel pipe piles used in foundation pit support, comprising clamps, clamping hydraulic shafts, an upper plane, lifting hydraulic shafts, and a main plane. The clamping hydraulic shafts are mounted on the upper plane, with four shafts installed. The lifting hydraulic shafts are fixed to the main plane, with their output ends connected to the upper plane. Both the upper plane and main plane are designed to sleeve onto the forepoling grouted steel pipe piles. The recovery device and method disclosed in this invention can significantly improve the recycling rate of forepoling grouted steel pipe piles, thereby substantially reducing construction costs. This innovation not only enhances economic efficiency but also actively promotes low-carbon emission reduction during construction, making positive contributions to environmental protection and sustainable development.Type: ApplicationFiled: September 19, 2025Publication date: July 9, 2026Inventors: Panpan Guo, Shaoming Wan, Ming Zhang, Ning Li, Junjie Dong, Yixian Wang, Xian Li, Xuelong Hu, Zhanqi Wang, Gan Wang, Yan Liu
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Publication number: 20260195209Abstract: Provided is a cross-machine few-shot fault diagnosis method based on a retrospective prototypical network (RPN), which belongs to the technical field of fault diagnosis. First of all, through a multi-scale hybrid dilated convolutional feature extraction module, highly abstract sample features are extracted from a vibration signal acquired in a complex scenario. Then, a retrospective prototype representation and update method is proposed to optimize a class prototype with internal structures of data, more accurately reflecting a complex distribution of a class, and effectively reducing prototype oscillation and feature distribution differences between batches. In addition, a new similarity evaluation method, namely a central difference metric (CDM), is proposed to calculate a difference between the internal structures of the data, providing a more flexible similarity evaluation tool for a few-shot diagnosis task.Type: ApplicationFiled: September 10, 2025Publication date: July 9, 2026Inventors: Yi QIN, Qijun WEN, Yongfang MAO, Ning LI
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Patent number: 12676477Abstract: Systems and methods comprising a metering device located on an electricity distribution grid, the metering device comprising one or more processors and memory. The metering device can detect a drop in characteristic of electricity below a threshold indicating a fault on the electricity distribution grid. The metering device can generate, responsive to the drop in the characteristic of electricity below the threshold, a time series of a rate of change of the characteristic of electricity for a predetermined number of cycles subsequent to the detection of the drop. The metering device can determine, based on a comparison of the time series of the rate of change with a predetermined pattern, a location of the metering device on the electricity distribution grid relative to a location of the fault on the electricity distribution grid.Type: GrantFiled: June 17, 2024Date of Patent: July 7, 2026Inventors: Taylor Spalt, Ning Li, Marissa Hummon
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Publication number: 20260184713Abstract: Disclosed is a class of kinase inhibitors. Related pharmaceutical compositions and methods of making and using the kinase inhibitors are also disclosed.Type: ApplicationFiled: July 17, 2023Publication date: July 2, 2026Applicant: The United States of America, as represented by the Secretary, Department of Health and Human ServicInventors: Barry R. O'Keefe, Lin Du, Brice A.P. Wilson, Ping Zhang, Dongdong Wang, Juliana Martinez Fiesco, Ning Li, William J. Moore
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Patent number: 12669508Abstract: The present invention generally pertains to methods of preventing disulfide scrambling in non-reducing liquid chromatography-mass spectrometry analysis of a protein of interest. In particular, the present invention pertains to the addition of maleimide to a non-reducing liquid chromatography-mass spectrometry analysis of a protein to prevent disulfide scrambling.Type: GrantFiled: October 28, 2022Date of Patent: June 30, 2026Assignee: REGENERON PHARMACEUTICALS, INC.Inventors: Andrew Kleinberg, Yuan Mao, Ning Li
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Patent number: 12667100Abstract: A composition and use thereof. The composition comprises an active component a and an active component b; the active component a is a compound as shown in general formula A; and the active component b is at least one of compounds which have insecticidal, acaricidal or bactericidal activity and are different from the compound as shown in general formula A. The composition has the advantages of synergistic effect and expanding prevention and treatment spectrum, and can be used for preventing and treating various pests, particularly mite damage, and plant diseases caused by various fungi, bacteria, nematodes and viruses.Type: GrantFiled: January 28, 2022Date of Patent: June 30, 2026Assignee: SHANGDONG KANGIAO BIO-TECHNOLOGY CO., LTDInventors: Ning Li, Yingshuai Liu, Yingrui Cui, Xiangwei Liu, Ruibin Liu, Yunxiao Sun, Shien Fan, Yu Chen, Baohong Liu, Jiajie Niu, Jie Gao, Ruijie Feng, Qinan Han, Bin Li
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Patent number: 12663103Abstract: An ultrahigh-pressure acid-fracturing isodiametric hose assembly, comprising a hose body and a metal joint. The metal joint comprises an inner tube, a first outer tube the inner tube, and a second outer tube. The first outer tube and the second outer tube each is an independent pressing part. An external groove is provided at an outer wall of the inner tube. An end of the first outer tube comprises an internal ridge which matches the external groove for snapping. The terminal of the inner tube comprises a connecting portion. An outer wall of the inner tube comprises a first protrusion, and an inner wall of the first outer tube comprises a second protrusion engaging with the first protrusion. The hose body is clamped between the first protrusion and the second protrusion that are engaged. An inner wall of the second outer tube comprises multiple micro-protrusions.Type: GrantFiled: July 27, 2023Date of Patent: June 23, 2026Assignee: LUOHE LETONE HYDRAULICS TECHNOLOGY CO., LTD.Inventors: Hongliang Zhao, Zhian Liu, Peiyuan Wu, Feilong Zhang, Xingpeng Yang, Lili Lu, Yong Zhang, Yanhui Zhao, Pengfei Zhang, Ning Li
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Publication number: 20260145870Abstract: The embodiments of the present disclosure disclose a plastic bottle compression and recycling device. The plastic bottle compression and recycling device includes a housing, and a compression cavity, a binding part, a compression part, a feeding part, a conveying part, a discharging part and a controller that are located inside the housing.Type: ApplicationFiled: September 28, 2025Publication date: May 28, 2026Inventors: Jonathan Zhi Zhou Zhang, Enbo Zhang, Jialei Chen, Ning LI, Shaoyan Zhang, Peigui Wu, Cheng Zhang, Guiming Zhang, Binghong Liu, Yufeng Ren, Ling Ping, Yihua Zhang, Wenda Li, Yungui Li, Chunlai Liu, Tao Yuan, Yunli Wang, Shasha Pu, Donghui Huo, Lidan Zhao
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Patent number: 12630510Abstract: A drug containing, as an active ingredient, a compound having an antagonistic activity against an EP2 receptor in the prevention and/or treatment of a disease associated with the activation of an EP2 receptor, of formula (I-A): wherein all symbols have the same meanings as those described in the specification, or a pharmaceutically acceptable salt thereof.Type: GrantFiled: June 26, 2020Date of Patent: May 19, 2026Assignee: ONO PHARMACEUTICAL CO., LTD.Inventors: Akio Watanabe, Atsushi Yoshida, Yasuo Hirooka, Michael G. Yang, Ning Li
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Publication number: 20260119497Abstract: A latency-oriented Service Level Optimization system for multi-tenant databases. Latency's negative effect on Quality of Service is expressed in terms of a latency impact function to provide a latency impact-oriented SLO-guaranteed system that enables a database system to support multi-tenant latency-impact targets in a cost-effective fashion. In contrast to traditional latency management based on percentile guarantees, the present invention manages latency based on the latency probability density function for all latency values. Cost-effective management is attained through latency impact-oriented capacity planning and real-time latency impact target enforcement. The capacity planning estimates the feasibility of latency-impact targets while the target enforcement tracks and regulates the per-connection query latency distribution needed for accurate latency-impact target guarantee, avoiding both under-provisioning and over-provisioning.Type: ApplicationFiled: October 27, 2025Publication date: April 30, 2026Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Ning LI, Hong JIANG, Hao CHE, Zhijun WANG, Minh Q. NGUYEN, Todd ROSENKRANTZ
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Patent number: 12615014Abstract: A test device and a method for testing a photovoltaic module, for testing anti-stepping performance of the photovoltaic module. The test device includes first and second test members spaced apart along a first direction. The first and second test members are configured to abut against the photovoltaic module and apply a preset load to the photovoltaic module. The first test member is at a first position when the first test member abuts against the photovoltaic module, the second test member is at a second position when the second test member abuts against the photovoltaic module, and along a movement direction of the first and second test members in a horizontal plane, the first and second positions are alternately spaced apart, to simulate force on the photovoltaic module when an operator walks on the photovoltaic module.Type: GrantFiled: December 29, 2022Date of Patent: April 28, 2026Assignee: JINKO SOLAR (HAINING) CO., LTD.Inventors: Ning Li, Sen Yang, Pengjun Xiao, Bo Li, Jiaxiang Yin
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Publication number: 20260110690Abstract: The present invention generally pertains to methods of detecting host cell proteins. In particular, the present invention pertains to the use of a novel activity-based protein profiling probe to identify host cell proteins with lipase activity in a pharmaceutical formulation.Type: ApplicationFiled: December 22, 2025Publication date: April 23, 2026Inventors: Gaoyuan LIU, Xiaojing ZHENG, Ning LI
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Patent number: 12610786Abstract: A semiconductor layout structure includes: active layers, each active layer including a first active area and a second active area arranged adjacent to the first active area, the first active area including first transistor areas spaced apart from each other, the second active area including second transistor areas spaced apart from each other; and gate layers, each gate layer being arranged above a respective active layer, and including at least one first gate structure extending along a first direction, and second gate structures spaced apart from each other in the first direction, and the at least one first gate structure and the second gate structures being arranged adjacent to each other, the at least one first gate structure corresponding to the first transistor areas, and each second gate structure corresponding to a second transistor area.Type: GrantFiled: August 3, 2022Date of Patent: April 21, 2026Assignee: CHANGXIN MEMORY TECHNOLOGIES, INC.Inventors: Xiangyu Wang, Ning Li
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Patent number: 12606789Abstract: The present disclosure provides a perfusion system and a cell cultivation perfusion system, the perfusion system comprising: a pressure transfer component, the pressure transfer component including a belt and multiple pressure members disposed on the belt at intervals; a driving device, a driving connection being established between the driving device and the pressure transfer component; and at least one pipeline assembly, the at least one pipeline assembly including at least one pressable pipeline for fluid flow; wherein a press area is formed between the pressure transfer component and each of the at least one pressable pipeline, the multiple pressure members move with the belt, and at least a portion of the multiple pressure members press against the at least one pressable pipeline in the press area.Type: GrantFiled: December 8, 2022Date of Patent: April 21, 2026Assignee: SHANGHAI RUIYU BIOTECH CO., LTD.Inventors: Xuan Wang, Ning Li, Rui Chen
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Publication number: 20260101440Abstract: A power module for a solid-state circuit breaker, including: first and second substrates; first and second terminals; and a chip assembly disposed between the first and second substrates. The chip assembly includes: a plurality of bottom-side transistors having drains electrically coupled to a first substrate and including first and second sets of bottom-side transistors; a plurality of top-side transistors having drains electrically coupled to a second substrate and including first and second sets of top-side transistors; a gate drive board including bottom-side and top-side metal layers; and first and second metal connectors disposed on opposite sides of the gate drive board, the first metal connector being electrically coupled to sources of the first set of bottom-side transistors and the first set of top-side transistors, the second metal connector being electrically coupled to sources of the second set of bottom-side transistors and the second set of top-side transistors.Type: ApplicationFiled: October 1, 2025Publication date: April 9, 2026Inventors: Chenyang LIU, Ning LI, Hongzhi SUN, Baoyun BI, Jiamin CHEN, Jiawei LIU, Louis JANINET
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Patent number: 12594370Abstract: An optimizing device for freely switching RBC removal and plasma exchange are provided, which is used to solve the problems in the prior art that the treatment effect is poor, the consumption of consumables is excessive, and the application range is narrow. According to the device, an additional hanging hook is added, a plasma exchange output pipeline is modified to be separated from the plasma collection pump and to be installed to the additional hanging hook. Then, the RBC recirculation tube is clamped through a freely movable cassette, so that the flow rate control of a plasma collection pump is released. Thereafter, HCT data is adjusted, and liquid is compensated, so that the RBC removal or replacement, lymphoplasma exchange and plasma exchange can be freely switched, which can meet the clinical treatment needs, optimize the process and reduce the cost. Therefore, the application range of a pipeline is greatly increased.Type: GrantFiled: October 24, 2024Date of Patent: April 7, 2026Assignee: XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITYInventors: Cheng Mei, Bijuan Li, Yuanjun Jiang, Wenyu Yin, Xi Yuan, Zhimin Zhang, Linxi Shi, Ying Tan, Guangbo Tang, Ning Li
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Patent number: 12595279Abstract: Disclosed are a modified cytidine compound, i.e. a new derivative cytidine generated by adding a guanidyl at position 4 of a cytidine, and a nucleic acid containing the modified compound, for example, RNA. The nucleic acid containing the modified cytidine, especially mRNA, can significantly increase the expression quantity of the mRNA in vivo.Type: GrantFiled: February 12, 2020Date of Patent: April 7, 2026Assignee: STEMIRNA THERAPEUTICS CO., LTD.Inventors: Yunsong Cai, Hangwen Li, Lianxiao Liu, Ning Li
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Patent number: 12590354Abstract: The invention provides a copper alloy strip, wherein the copper alloy comprises the following components in percentage by mass: 0.1 wt %-1.0 wt % of Cr, 0.01 wt %-0.2 wt % of Si, 0.01 wt %-1.0 wt % of X and the balance of Cu and inevitable impurities, wherein X is at least one of Fe, Ti, Zr, Ag, Zn and Sn; on a section of the copper alloy strip perpendicular to a rolling direction, the number of second-phase particles having a particle size of 5 nm or below 5 nm is A, the number of second-phase particles having a particle size of 100 nm or above 100 nm is B, and A/B is greater than or equal to 3.Type: GrantFiled: June 20, 2023Date of Patent: March 31, 2026Assignees: NINGBO BOWAY ALLOY PLATE AND STRIP CO., LTD., NINGBO POWERWAY ALLOY MATERIAL CO.,LTD., NINGBO BOWAY NEW MATERIAL CO.,LTDInventors: Xiangpeng Meng, Yongjun Pei, Jibao Li, Ning Li, Xuan Zhang, Ming Zhang, Renchang Hu, Lei Zhong
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Patent number: 12592369Abstract: Methods of manufacturing memory devices are provided. The method comprises pre-cleaning a top surface of a film stack, the film stack comprising alternating layers of a first material layer and a second material layer and having one or more of a memory hole and a slit pattern opening extending through the film stack; exposing the top surface of the film stack to a growth inhibitor; selectively depositing a silicon-containing dielectric layer in a region of the film stack; and densifying the silicon-containing dielectric layer. The processing method is performed in a processing tool without breaking vacuum.Type: GrantFiled: March 28, 2023Date of Patent: March 31, 2026Assignee: Applied Materials, Inc.Inventors: Tomohiko Kitajima, Ning Li, Chang Seok Kang, Naomi Yoshida
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Publication number: 20260086071Abstract: The present invention generally pertains to methods of quantifying free fatty acids in a pharmaceutical formulation. In particular, the present invention pertains to a method of quantifying free fatty acids released from polysorbate hydrolysis in a pharmaceutical formulation comprising a pharmaceutical product, polysorbate and free fatty acids, using liquid chromatography-mass spectrometry, without the use of an extraction step.Type: ApplicationFiled: December 1, 2025Publication date: March 26, 2026Inventors: Sisi ZHANG, Hui Xiao, Ning Li