Abstract: A method for constructing a large-span station by two-wing open type semi-covered excavation and semi-reverse construction, is divided into three stages of excavation. First, excavate a first-stage inner small foundation pit, then excavate a second-stage annular foundation pit within the first-stage retaining piles and outside the range of the first-stage inner small foundation pit, and finally excavate a third-stage semi-covered excavation foundation pit below the first-stage inner small foundation pit and the second-stage annular foundation pit. By setting graded retaining piles, middle upright post piles, middle top plates, local waist beams and local concrete supports in the soil-rock combination strata, so that the force transfer between the foundation pit enclosure and the station main body structures and the underlying rock layer is clear and reliable, and a stable frame structure is achieved.

Abstract: A method of a polyurethane foam includes the following steps of: (1) simultaneously pumping a mixed solution prepared from hydrogen peroxide, an organic acid, a catalyst and a stabilizer and a vegetable oil into a first microstructured reactor of a micro-channel modular reaction device for reacting to obtain a reaction solution containing epoxidized vegetable oil; (2) simultaneously pumping the reaction solution containing the epoxidized vegetable oil obtained from the step (1) and a compound of formula III into a second microstructured reactor of the micro-channel modular reaction device for reaction to obtain a vegetable oil polyol; and (3) reacting the vegetable oil polyol prepared from the step (2) with a foam stabilizer, a cyclohexylamine, an isocyanate and a foaming agent cyclopentane for foaming so as to prepare a rigid polyurethane foam.

Abstract: A P2X3 and/or P2X2/3 receptor antagonist of formula (I), a pharmaceutical composition comprising the same, and a use thereof in preparing a drug for preventing or treating a disease mediated by the P2X3 and/or P2X2/3 receptor antagonist.

Abstract: The present disclosure pertains to methods for producing aflibercept from a host cell cultured in a chemically defined medium (CDM) including purification of aflibercept, wherein aflibercept following purification includes aflibercept variants that have at least one oxidized amino acid residue selected from the group consisting of tryptophan, histidine and a combination thereof.

Abstract: A damping ratio measuring device for consolidation equipment includes a bracket, a consolidation pressure device and a sleeve. The consolidation pressure device is set at the top of the bracket, and the output direction of the consolidation pressure device is directly below. The bottom of the consolidation pressure device is connected with a pressurized piston. A displacement sensor is set on the pressurized piston. The sleeve is set directly below the consolidation pressure device, the pressurized piston extends from the top of the sleeve, the diameter of the pressurized piston is the same as the inner diameter of the sleeve, the bottom of the sleeve is sealed with a support plate, and there are two bending element sensors at the top of the support plate and the bottom of the pressurized piston.

Abstract: A full-face shaft tunnel boring machine system includes a tunnel boring machine cutterhead device for tunneling downwards in a shaft; a full-hydraulic formwork device for supporting and walling in a wellbore; and an upper muck-discharge system for vertically conveying rock mucks generated by tunneling. The tunnel boring machine cutterhead device comprises a vertical guide frame, a cutter-expanded boring head and an advanced cutterhead that are fixedly connected in a vertical order from top to bottom so as to form an integrated structure. The vertical guide frame is a hollow cylindrical structure and driven to rotate around an axis of the vertical guide frame by a power mechanism, and an outer wall of the vertical guide frame is provided with multiple sets of first guide rollers.

Abstract: The application relates to a method for antenna port indication. A terminal receives information indicating an antenna port set of a pilot from a base station. The antenna port set is used for a resource block (RB) set and the pilot is used for data demodulation. The terminal determines the antenna port set based on the received information. By implementing the solution in the application, transmission resource utilization is improved.

Abstract: A preparation method of a flexible polyurethane foam includes the following steps of: (1) subjecting an epoxidized vegetable oil, a benzoylformic acid, a basic catalyst, and an inert solvent to a ring-opening reaction in a first microchannel reactor of a microchannel reaction device to obtain a vegetable oil polyol; (2) subjecting the vegetable oil polyol obtained in the step (1), a propylene oxide and an inert solvent to an addition polymerization reaction in a second microchannel reactor of the microchannel reaction device to obtain a vegetable oil polyol for flexible polyurethane foam; and (3) using the vegetable oil polyol for flexible polyurethane foam obtained in the step (2) as the unique polyol, and subjecting the same and an isocyanate polyol to a foaming reaction to obtain the flexible polyurethane foam.

Abstract: Provided is a light source system, including: an excitation light source emitting excitation light; a wavelength conversion device having conversion and reflective regions located in different planes and time-sequentially located in optical path of the excitation light, the conversion region configured for converting at least part of the excitation light into excited light, and the reflective region configured for reflecting the excitation light; collection lens assembly configured to guide light from the conversion region to propagate along first direction to obtain first light, and guide the excitation light from the reflective region to propagate along second direction to obtain second light; first guide device configured to guide the excited light in the first light to exit along first path; and second guide device configured to guide the second light to propagate along second path. The first guide device combines the excited light and the second light to obtain source light.

Abstract: A detection system according to an aspect of the present disclosure includes: at least one memory configured to store instructions; and at least one processor configured to execute the instructions to: acquire a number of registered commodities for which commodity registration has been performed based on notification information given upon the commodity registration by a customer; acquire a number of to-be registered commodities for which the customer is to perform commodity registration; detect a discrepancy between the number of registered commodities and the number of to-be registered commodities; and output a detection result.

Abstract: A detection system according to an aspect of the present disclosure includes: at least one memory configured to store instructions; and at least one processor configured to execute the instructions to: acquire a number of one or more products to be registered based on an image in which a customer reads one or more product symbols with a scanner; acquire a number of one or more products registered by the customer; detect discrepancy between the number of the one or more products to be registered and the number of the one or more registered products; and output a detection result.

Abstract: Provided is an isolated monoclonal antibody targeting B-cell maturation antigen (BCMA), the antibody can bind to both human BCMA and monkey BCMA. Also provided are a nucleic acid encoding the antibody, a method for producing the antibody, and a pharmaceutical composition comprising the antibody.

Abstract: The present invention pertains to methods for characterizing proteins in a sample using native capillary electrophoresis-mass spectrometry. The present invention pertains to methods for detecting and/or discriminating between post-translational modification variants of an antibody of interest in a sample, detecting and/or discriminating between antibodies in an antibody mixture, and characterizing monospecific antibody side products in a bispecific antibody sample.

Abstract: The invention provides a copper alloy strip, wherein the copper alloy comprises the following components in percentage by mass: 0.1 wt %-1.0 wt % of Cr, 0.01 wt %-0.2 wt % of Si, 0.01 wt %-1.0 wt % of X and the balance of Cu and inevitable impurities, wherein X is at least one of Fe, Ti, 5 Zr, Ag, Zn and Sn; on a section of the copper alloy strip perpendicular to a rolling direction, the number of second-phase particles having a particle size of 5 nm or below 5 nm is A, the number of second-phase particles having a particle size of 100 nm or above 100 nm is B, and A/B is greater than or equal to 3.

Abstract: Methods and precursors for selectively depositing a metal film on a silicon nitride surface relative to a silicon oxide surface are described. The substrate comprising both surfaces is exposed to a blocking compound to selectively block the silicon oxide surface. A metal film is then selectively deposited on the silicon nitride surface.

Abstract: A structure including a bottom electrode, a phase change material layer, the phase change material layer includes a similar lattice constant as a lattice constant of the substrate, a top electrode on and vertically aligned with the phase change material layer, a dielectric material horizontally isolating the bottom electrode from the top electrode and the phase change material layer. A structure including a phase change material layer selected from amorphous silicon, amorphous germanium and amorphous silicon germanium, a top electrode on the phase change material layer, a bottom electrode, a dielectric material isolating the bottom electrode from the top electrode and the phase change material layer. Forming a bottom electrode, forming a phase change material layer adjacent to the bottom electrode, forming a top electrode above the phase change material, forming a dielectric material horizontally isolating the bottom electrode from the top electrode and the phase change material layer.

Abstract: Apparatus and methods to control the phase of power sources for plasma process regions in a batch process chamber. A master exciter controls the phase of the power sources during the process sequence based on feedback from the match circuits of the respective plasma sources.

Abstract: Some implementations of the present disclosure provide a method that include: accessing a plurality of tables that describe a relational data model for a hierarch of exploration data assets, wherein the relational data model defines the hierarchy of exploration data assets and attributes at each level of the hierarchy, and wherein multiple databases encode the hierarchy of exploration data assets; querying the hierarch of exploration data assets according to one or more data quality rules capable of identifying defects in the hierarchy of exploration data assets; identifying instances of data records that fail to meet the one or more data quality rules; based on the identified instances, calculating one or more data quality metrics for the hierarchy of exploration data assets; and generating an alert that includes: the identified instances of data records, or the calculated one or more data quality metrics.

Abstract: Provided are an NLP-based method for constructing a variant literature interpretation knowledge base, an interpretation method, and an electronic device. The method for constructing the variant literature interpretation knowledge base includes: obtaining disease-related literature; constructing, based on the disease-related literature, a database of entities associated with genes and variants; constructing a literature evidence knowledge graph for interpretation of variant literature; and performing evidence extraction on the literature evidence knowledge graph to obtain evidence corresponding to an entity, and constructing, based on the evidence and the database, the variant literature interpretation knowledge base. In this way, the literature evidences can be more comprehensive and systematic.