Patents by Inventor Ning Zhou

Ning Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210292852
    Abstract: A grading model for detecting the degree of benignity/malignancy of a thyroid tumor and its applications are disclosed. The model grades the changes in an imprinted gene in a thyroid tumor by calculating an expressed quantity of the imprinted gene with a loss of imprinting, an expressed quantity of the imprinted gene with a copy number variation, and a total expressed quantity of the imprinted gene. The detection model and device disclosed herein enable intuitive observation of the expression of an imprinted gene with a loss of imprinting in a tissue or cell sample taken from a patient with a thyroid tumor. By labeling the imprinted gene in situ, changes in the imprinted gene can be objectively, intuitively, and precisely detected at an early stage. Moreover, a quantitative model is provided. Thus, the disclosure contributes greatly to the diagnosis of thyroid tumors.
    Type: Application
    Filed: July 29, 2019
    Publication date: September 23, 2021
    Inventors: Tong Cheng, Ning Zhou
  • Publication number: 20210285055
    Abstract: A grading model for detecting the degree of benignity/malignancy of a lung tumor and its applications are disclosed. The model grades the changes in an imprinted gene in a lung tumor by calculating an expressed quantity of the imprinted gene with a loss of imprinting, an expressed quantity of the imprinted gene with a copy number variation, and a total expressed quantity of the imprinted gene. The detection model and device disclosed herein enable intuitive observation of the expression of an imprinted gene with a loss of imprinting in a tissue or cell sample taken from a patient with a lung tumor. By labeling the imprinted gene in situ, changes in the imprinted gene can be objectively, intuitively, and precisely detected at an early stage. Moreover, a quantitative model is provided. Thus, the disclosure contributes greatly to the diagnosis of lung tumors.
    Type: Application
    Filed: July 10, 2019
    Publication date: September 16, 2021
    Inventors: Tong Cheng, Ning Zhou
  • Patent number: 11116359
    Abstract: Air-based fryer including a food preparation chamber including an outer wall, an inner wall defining a food receiving space with an air inlet and an air discharge opening, and a circulation channel defined between the outer wall and the inner wall. The fryer includes an air heater for heating air in the food preparation chamber, a fan for moving a flow of hot air successively through the air inlet, the food receiving space, the discharge opening, and the channel. The fryer includes a steam generator including at least one nozzle extending into the food receiving space for spraying temperature-controlled steam onto the food; and a controller adapted to control the steam generator to spray steam to food placed in the food receiving space for a first predetermined period, and to control the air heater and the fan to circulate hot air to the food for a subsequent second predetermined period.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: September 14, 2021
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Yun Chen, Ning Zhou, Wen Sun, Xiaoyun Kui
  • Publication number: 20210267198
    Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.
    Type: Application
    Filed: April 7, 2021
    Publication date: September 2, 2021
    Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
  • Patent number: 11098322
    Abstract: This invention relates in part to plant breeding and herbicide tolerant plants. This invention includes a novel aad-1 transformation event in corn plants comprising a polynucleotide sequence, as described herein, inserted into a specific site within the genome of a corn cell. In some embodiments, said event/polynucleotide sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. Additionally, the subject invention provides assays for detecting the presence of the subject event in a sample (or corn grain, for example). The assays can be based on the DNA sequence of the recombinant construct, inserted into the corn genome, and on the genomic sequences flanking the insertion site. Kits and conditions useful in conducting the assays are also provided.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: August 24, 2021
    Assignee: DOW AGROSCIENCES LLC
    Inventors: Yunxing Cory Cui, Jill Bryan, Donald Maum, Greg Gilles, Terry Wright, Jennifer Hamilton, Nicole Arnold, Nathan VanOpdorp, Tina Kaiser, Ning Zhou
  • Publication number: 20210198479
    Abstract: A method of forming a graphic article is described such as a tape or sheet, comprising a PLA-based film. The PLA-based film comprises a semicrystalline polylactic acid polymer; a second polymer such as polyvinyl acetate polymer having a glass transition temperature (Tg) of at least 25° C.; and plasticizer. The graphic article is typically a tape or sheet that may further comprise a (e.g. pressure sensitive) adhesive and a low adhesion backsize or a release liner. The graphic article can be suitable for various end-uses.
    Type: Application
    Filed: March 15, 2021
    Publication date: July 1, 2021
    Inventors: Ning Zhou, John A. Nielsen
  • Publication number: 20210180158
    Abstract: A nickel base superalloy powder for additive manufacturing applications is disclosed. The alloy powder has the following broad weight percent composition: C ?0-0.1 Mn 0.5 max. Si ??0-0.03 Cr ?4-16 Fe ?0-1.5 Mo 0-6 W 0-8 Co ?0-15 Ti 0-2 Al 0.5-5.5 Nb 0-6 Ta ?7.5-14.5 Hf ?0-2.0 Zr ?0-0.1 Re 0-6 Ru 0-3 B ??0-0.03 The balance of the alloy is at least 50% nickel and the usual impurities. An article of manufacture made from the alloy is also disclosed.
    Type: Application
    Filed: January 23, 2020
    Publication date: June 17, 2021
    Inventors: Ning Zhou, Kyle B. Stritch, Tao Wang, Stephane A.J. Forsik, Gian A. Colombo, Samuel J. Kernion, Mario E. Epler, Austin Dicus
  • Publication number: 20210178798
    Abstract: A multilayer article including a film layer having a textured first surface and an opposite second surface, wherein the film layer is printable, and a nonwoven material layer bonded to the second surface of the film layer. The film layer may include a semi-crystalline polylactic acid and may be receptive to inkjet printing.
    Type: Application
    Filed: December 14, 2018
    Publication date: June 17, 2021
    Inventors: Denis Terzic, Ning Zhou, Byron E. Trotter
  • Patent number: 11020955
    Abstract: A method of method of forming or repairing a superalloy article having a columnar or equiaxed or directionally solidified or amorphous or single crystal microstructure includes emitting a plurality of laser beams from selected fibers of a diode laser fiber array corresponding to a pattern of a layer of the article onto a powder bed of the superalloy to form a melt pool; and controlling a temperature gradient and a solidification velocity of the melt pool to form the columnar or single crystal microstructure.
    Type: Grant
    Filed: December 5, 2019
    Date of Patent: June 1, 2021
    Assignee: General Electric Company
    Inventors: William Thomas Carter, Marshall Gordon Jones, Lang Yuan, Ning Zhou, Steven Jude Duclos
  • Publication number: 20210122890
    Abstract: Presently described are polylactic acid polymer based films comprising a structured surface and articles. In one embodiment, the film comprises a semicrystalline polylactic acid polymer; a second polymer such as polyvinyl acetate polymer having a glass transition temperature (Tg) of at least 25° C.; and plasticizer. Articles are also described such as a tape or sheet, comprising the structured PLA-based film and a layer of (e.g. pressure sensitive) adhesive disposed on the film. In some embodiments, the tape or sheet further comprises a low adhesion backsize or a release liner. The article can be suitable for various end-uses. In one embodiment, the tape is a paint masking tape. In another embodiment, the tape is a floor marking tape.
    Type: Application
    Filed: February 6, 2017
    Publication date: April 29, 2021
    Inventors: Derek J. Dehn, Graham M. Clarke, Joseph T. Bartusiak, Ning Zhou, Jeffrey A. Carlson
  • Patent number: 10982090
    Abstract: A graphic article comprising a Poly lactic acid (PLA) based film and in particular, an ink layer depicting a graphic is described. The PLA based film comprises a semicrystalline polylactic acid polymer, a second of a polyvinyl acetate polymer having a glass transition temperature (Tg) of at least 25° C., and plasticizer. The article is typically a tape or sheet that may further comprise an adhesive (e.g. pressure sensitive) and a low adhesion backsize or a release liner. A method of forming a graphic article using the film of the invention is also disclosed.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: April 20, 2021
    Assignee: 3M Innovative Properties Company
    Inventors: Ning Zhou, John A. Nielsen
  • Patent number: 10973229
    Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: April 13, 2021
    Assignees: Dow Agrosciences LLC, M.S. Technologies, L.L.C.
    Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
  • Publication number: 20210071261
    Abstract: The present application refers to a method for cancer diagnosis via biopsy samples. The method grades the expression status of imprinted genes by calculating the change of the expression of imprinted genes with loss of imprinting, the expression of imprinted genes with copy number variation, and the total expression of imprinted genes in tumor; wherein the imprinted genes are Z1 and/or Z16. Z1 is Gnas, and Z16 is Snrpn/Snurf. The method in the present application presents the expression of loss of imprinting in biopsy samples in a direct way for the first time, which can provide a quantitative model, to make a great contribution especially to the early diagnosis of transformation from tumor to cancer and screening of tumor.
    Type: Application
    Filed: November 17, 2020
    Publication date: March 11, 2021
    Applicant: LISEN IMPRINTING DIAGNOSTICS, INC.
    Inventors: Tong CHENG, Ning ZHOU
  • Patent number: 10908571
    Abstract: A computer system provides real-time control of power dispatch for a power system. The power system includes power generators, renewable power generators, load, and storage devices interconnected by a power grid. The computer system obtains input data, and solves an online multi-period power dispatch problem formulated from the input data and incorporates AC power flow in the power grid. The computer system generates control signals according to a solution of the online multi-period power dispatch problem, and sends the control signals to controllers of the power generators and the storage devices. In every time period during operation of the power system, the computer system updates the solution, generates updated control signals according to the updated solution, and sends the updated control signals to the controllers to continuously operate the power system with minimized operational cost while fully utilizing renewable power output.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: February 2, 2021
    Assignee: Bigwood Technology, Inc.
    Inventors: Hsiao-Dong Chiang, Lin Zeng, Pei Bie, Buhan Zhang, Ning Zhou
  • Patent number: 10870627
    Abstract: A salt of a quinazoline derivative (N-[4-(3-chlorine-4-fluoroanilino)]-7-(3-morpholinepropanol)-6-(2-fluoroacrylamide)-quinazoline, the structure thereof is as represented by formula I). Compared with a known quinazoline derivative, the salt of the quinazoline derivative has one or more improved properties and at least has better water solubility, wherein a citrate, a benzene sulfonate, and an ethanedisulphonate thereof further have better crystallinity and are not easy to absorb moisture.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: December 22, 2020
    Assignee: SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.
    Inventors: Guangxin Xia, Di Li, Ning Zhou, Ao Chen, Liang Zhao, Jiansheng Han, Yanjun Liu
  • Patent number: D927217
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: August 10, 2021
    Assignee: Bradley Corporation
    Inventors: Simon Holzmann, Stefan Hillenmayer, Ning Zhou, Laura Beth Stang
  • Patent number: D927218
    Type: Grant
    Filed: October 2, 2019
    Date of Patent: August 10, 2021
    Assignee: Bradley Corporation
    Inventors: Laura Beth Stang, Simon Holzmann, Stefan Hillenmayer, Ning Zhou
  • Patent number: D927885
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: August 17, 2021
    Assignee: Bradley Corporation
    Inventors: Simon Holzmann, Stefan Hillenmayer, Ning Zhou, Laura Beth Stang
  • Patent number: D936998
    Type: Grant
    Filed: October 2, 2019
    Date of Patent: November 30, 2021
    Assignee: Bradley Corporation
    Inventors: Laura Beth Stang, Simon Holzmann, Stefan Hillenmayer, Ning Zhou
  • Patent number: D937004
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: November 30, 2021
    Assignee: Bradley Corporation
    Inventors: Simon Holzmann, Stefan Hillenmayer, Ning Zhou, Maximilian Schneider, Laura Beth Stang, Vincenz Marschall