Abstract: A method may include presenting a user interface, the user interface including: a graph presentation area; and a graph link type confirmation area; executing a knowledge graph database search query; in response to the executing, receiving a set of tuple objects corresponding to relationships between entities in the knowledge graph database; populating the graph presentation area with representations of the entities and links connecting the representations of the entities; populating the graph link type confirmation area with a selectable user interface element configured to confirm a relationship of the relationships between entities; receiving activation of the selectable user interface element; and in response to receiving the activation, updating the graph presentation area.

Abstract: Systems and methods for novel uses and/or improvements to blockchains and blockchain technology. As one example, systems and methods are described herein for self-validating digital records that may be transferred in real-time through a cross-network registry. For example, in a conventional system, minting a token (e.g., a digital record) involves writing a self-executing program that defines the transfer rules of the digital record. Once the self-executing program is written, it is deployed on a blockchain, and the digital record is minted by publishing it to a blockchain.

Abstract: Apparatuses, systems, program products, and method are disclosed for detecting suitability of machine learning models for datasets. An apparatus includes a training evaluation module configured to calculate a first statistical data signature for a training data set of a machine learning system using one or more predefined statistical algorithms. An apparatus includes an inference evaluation module configured to calculate a second statistical data signature for an inference data set of a machine learning system using one or more predefined statistical algorithms. An apparatus includes a score module configured to calculate a suitability score describing the suitability of a training data set to an inference data set as a function of a first and a second statistical data signature. An apparatus includes an action module configured to perform an action related to a machine learning system in response to a suitability score satisfying an unsuitability threshold.

Abstract: Described herein are techniques of using machine learning to automatically extract clinical variable values for subjects from clinical record data. The techniques designate certain clinical variables as hybrid variables that can be assigned values by machine learning model prediction. The techniques process, using a machine learning model trained to predict a value of a hybrid variable, clinical record data associated with a subject to obtain a predicted hybrid variable value and an associated confidence score. The techniques set the value of the hybrid variable for the subject to the predicted hybrid variable value when the model prediction is of sufficiently high confidence.

Abstract: The present inventions provide a concise panel of chromatography-based stability-indicating methods for evaluating in vitro transcribed (IVT) mRNA under various conditions, including varying types and degrees of stress conditions, as part of a forced degradation study. The inventions also provide that addition of EDTA to the mRNAs prior to heat exposure reduces the extent of mRNA degradation, that the transcripts are fragmenting via a divalent metal-ion mediated pathway. The inventions also provide the application of the methods to evaluate the critical quality attributes (CQAs) of mRNAs as well as to detect intrinsic process and product related impurities.

Abstract: Anti-VEGF proteins including the VEGF trap protein aflibercept can be produced to have a low level of an aspartyl protease (e.g., a low level of cathepsin D), such as less than 1 ppm of the aspartyl protease.

Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.

Abstract: A system, apparatus and method for managing plurality of assets in technical installation is provided. The method includes receiving, by a processing unit, a set of requirements for managing the plurality of assets, selecting one or more assets from the assets based on the received set of requirements, mapping the one or more assets to corresponding sensing units, extracting information associated with the selected one or more assets and the received set of requirements, determining performance indicator based on information extracted from the knowledge base and mapped sensing units, defining workflow to be executed based on the determined at least one performance indicator, selecting configured machine learning model from a set of machine learning models based on the defined workflow, and determining an outcome of the selected machine learning model based on the received set of requirements.

Abstract: Implementations set forth herein relate to assigning users to cohorts and generating assistant content for presenting to the user based on their respectively assigned cohort and to reduce user churn out. Each cohort can belong to a plurality of cohorts that vary according to the level of experience, proficiency, and/or engagement that a user has historically exhibited with respect to a particular application and/or feature. A user can be assigned to multiple cohorts in circumstances in which a user may be proficient with respect to certain features of an application but not other features. When a user is estimated to be churning out or otherwise disengaging with respect to a particular feature, assistant content associated with that particular feature can be generated and rendered at a particular time that may not distract the user and may result in further engagement with the particular feature.

Abstract: An apparatus for wireless communications at a first UE may include a memory and at least one processor couple to the memory. The memory and the at least one processor may be configured to select one or more of a PC or a transmission scheme in response to the first UE meeting a speed state threshold. The memory and the at least one processor may be further configured to transmit a sidelink transmission using the one or more of the PC or the transmission scheme based on the first UE meeting the speed state threshold.

Abstract: Disclosed herein is a collection and dissemination system and method for attain structure characteristics information directly from encoded light signals produced by lights mounted to structures. An exemplary aircraft includes a light receiver, a data communication device, a processor, and a memory device. The light receiver receives light from a light-emitting device mounted to a structure. The memory device stores computer-executable code configured to cause the processor to perform steps of converting the light received by the light receiver into a data signal and transmitting the data signal to a navigation server via the data communication device, a network node, and a network.

Abstract: Embodiments disclosed herein include electronic packages. In an embodiment, the electronic package comprises a first package, wherein the first package comprises, a first package substrate, a first die over the first package substrate, a first mold layer over the first package substrate and around the first die, and a plurality of through mold interconnects (TMIs) through the first mold layer. The electronic package may further comprise a second package electrically coupled the first package by the TMIs, wherein the second package comprises a second package substrate, a second die over the second package substrate, and a solder resist over a surface of the second package substrate opposite from the second die. In an embodiment, the electronic package may also comprise a barrier between the first package and the second package.

Abstract: The present disclosure is directed to rapid detection and analysis of biological components using surface-enhanced Raman spectroscopy (SERS). One general aspect includes a method for preparing biological components from a biological sample for label-free SERS. The method also includes providing a Raman-background-free surfactant buffer to the biological sample. The method also includes agitating and heating the biological sample in the buffer to accelerate a lysis process thereby decomposing structural components of the biological sample. The structural components are substantially free of Raman background interference and are optimized for SERS signal enhancement.

Abstract: A method may include receiving, via a computing system, a request to generate one or more visualizations based on one or more datasets provided by an industrial device within an industrial system. The computing system may be communicatively coupled to the industrial device via a data backplane. The method may also involve accessing a visualization platform system in response to receiving the request, sending design data associated with the one or more visualizations to the visualization platform system, and receiving a visualization project file for execution by the computing system from the visualization platform system. The visualization project file may be generated based on the design data. The method may also include generating the one or more visualizations based on the visualization project file and presenting the one or more visualizations via an electronic display device.

Abstract: An online cloud application platform for global navigation of multiple online cloud-based applications is provided. The online cloud application platform is configured to provide a plurality of online cloud-based applications. While providing a current application among the plurality of online cloud-based applications, an event identifying a function request decoupled from a static navigation route is received via a cross-application routing handler. Based on a set of dynamically modifiable configuration data of the online cloud application platform, which application among the plurality of online cloud-based applications to handle the function request is dynamically determined. Based on the set of dynamically modifiable configuration data of the online cloud application platform, a corresponding dynamically determined cross-application navigation route to handle the event is determined.

Abstract: The present invention relates to a polyethylene composition comprising a base resin which comprises (A) a first ethylene homo- or copolymer fraction, and (B) a second ethylene copolymer fraction, wherein fraction (A) has a lower molecular weight than fraction (B), fraction (A) is present in an amount of 45.0 to 55.0 wt. %, preferably 46.0 to 53.0 wt. %, more preferably 46.5 to 52.0 wt. %, based on the total weight of the base resin, fraction (B) is present in an amount of 55.0 to 45.0 wt. %, preferably 54.0 to 47.0 wt. %, more preferably 53.5 to 48.0 wt. %, based on the total weight of the base resin, the base resin has a density of 945 kg/m3 to 958 kg/m3, more preferably of 947 to 956 kg/m3, and most preferably of 948 kg/m3 to 954 kg/m3, the polyethylene composition has a melt flow rate MFR5 of 0.15 to 0.30 g/10 min, preferably of 0.20 to 0.29 g/10 min, and still more preferably of 0.22 to 0.

Abstract: A system includes a turbine having an exhaust flow path, an inner turbine wall radially disposed along the exhaust flow path, an outer turbine wall disposed along the exhaust flow path and radially outward from the inner turbine wall, and an outer flow control vane configured to selectively extend radially inward from the outer turbine wall. A radial extent of the outer flow control vane is less than a radial distance between the inner turbine wall and the outer turbine wall. The outer flow control vane is disposed downstream of a last stage vane of the turbine and upstream of a last stage blade of the turbine. The turbine also includes an actuation assembly configured to actuate the outer flow control vane to cause the outer flow control vane to extend radially inward. The system also includes a controller configured to instruct the actuation assembly to actuate the outer flow control vane.

Abstract: A method may include presenting a user interface on a computing device, the user interface including: a service provider input element identifying a service provider; a service identifier input element identifying a service; and a graph presentation area; executing a knowledge graph database query using a combination of the service provider and the service as input to a knowledge graph database; receiving tuple results in response to the executing, the tuple results including an allocation value property of the service provider attributable to the service provider with respect to the service; and generating in the graph presentation area, an interactive graph based on the tuple results including: representations of entities including the service provider and the service in the tuple results as nodes in the interactive graph, wherein a representation of the service provider includes the allocation value; and links connecting the representations of entities.

Abstract: A method may include presenting a user interface, the user interface including: a graph presentation area; and a graph link type confirmation area; executing a knowledge graph database search query; in response to the executing, receiving a set of tuple objects corresponding to relationships between entities in the knowledge graph database; populating the graph presentation area with representations of the entities and links connecting the representations of the entities; populating the graph link type confirmation area with a selectable user interface element configured to confirm a relationship of the relationships between entities; receiving activation of the selectable user interface element; and in response to receiving the activation, updating the graph presentation area.

Abstract: The present disclosure provides methods treating reversible hemophilic arthropathy of a joint in a human having hemophilia comprising administering to the human an effective amount of a chimeric protein or composition comprising a clotting factor and an Fc region.