Patents by Inventor Nobuo Aoki

Nobuo Aoki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5463025
    Abstract: A protein having human plasmin inhibiting activity, substantially equivalent reactivity with human plasmin to a human .alpha..sub.2 -plasmin inhibitor derived from plasma, a binding ability to human fibrin about 1/4 to about 1/3 of that of the human .alpha..sub.2 -plasmin inhibitor derived from plasma, and a molecular weight of about 50,000 to about 77,000.
    Type: Grant
    Filed: January 24, 1994
    Date of Patent: October 31, 1995
    Assignee: Teijin Limited
    Inventors: Yoshihiko Sumi, Yataro Ichikawa, Nobuo Aoki, Masami Muramatsu
  • Patent number: 5354487
    Abstract: Compositions of high lubrication and light coloration are disclosed in which a selected class of resins and rubbers is blended with a specified cured polybutadiene product. The cured product results from crosslinking more than 10% of vinyl bonds in a butadiene polymer having a vinyl bond content of not less 20% by mol in terms of its monomer unit. Also disclosed are solid lubricants comprising a specified fluorinated cured polybutadiene and compositions containing the solid lubricant.
    Type: Grant
    Filed: April 5, 1991
    Date of Patent: October 11, 1994
    Assignee: Nippon Oil Co., Ltd.
    Inventors: Nobuo Aoki, Shinichiro Suzuki, Hisatake Sato
  • Patent number: 5343103
    Abstract: Power supplying unit to be used for supplying power to such a load as the motor for driving a submerged pump that scoops liquid out of a tank storing low temperature liquid like LNG and so forth. The power supplying unit has a ceramic sleeve fixed to the flange, a penetrating conductor inserted into this ceramic sleeve, and the ceramic sleeve and the penetrating conductor are coupled air-tightly to each other inside the flange (inside the tank) sealed outside the flange with a bellows of semi-mountain construction in cross section. The bellows has an elasticity and is mounted, when the ceramic sleeve and the penetrating conductor are linearly expanded at the maximum temperature during practical or normal use, or at the temperature slightly higher than the said level. The bellows is mounted between the ceramic sleeve and the penetrating conductor in a state where it is displaced to its maximum length due to its self elasticity.
    Type: Grant
    Filed: December 12, 1990
    Date of Patent: August 30, 1994
    Assignees: Tokyo Gas Co., Ltd., Furukawa Electric Co., Ltd.
    Inventors: Nobuo Aoki, Ikuo Aizawa, Keisuke Yokoi, Hideo Negishi
  • Patent number: 5264490
    Abstract: A particulate polybutadiene crosslinked material is disclosed along with a process of making the same. The particulate material has a substantially spherical, uniformly shaped configuration and comprises at least part of its surface layer occupied by a reaction product of polybutadiene and a silicone compound.
    Type: Grant
    Filed: October 16, 1991
    Date of Patent: November 23, 1993
    Assignee: Nippon Oil Co., Ltd.
    Inventors: Nobuo Aoki, Shinichiro Suzuki, Mitsuo Matsuno
  • Patent number: 5221738
    Abstract: cDNA encoding a human .alpha..sub.2 -plasmin inhibitor precursor protein represented by an amino acid sequence from the -39th Met to the 452nd Lys in FIG. 1 of the accompanying drawings; an amino acid sequence of a human .alpha..sub.2 -plasmin inhibitor precursor represented by an amino acid sequence from the -39th Met to the 452nd Lys in FIG. 1 of the accompanying drawings; and genomic DNA encoding a human .alpha..sub.2 -plasmin inhibitor protein which is composed of exons II, III, IV, V, VI, VII, VIII, IX and X in FIG. 4 of the accompanying drawings, said exons being bonded to one another via introns.
    Type: Grant
    Filed: December 9, 1991
    Date of Patent: June 22, 1993
    Assignee: Teijin Limited
    Inventors: Yoshihiko Sumi, Yataro Ichikawa, Masami Murakami, Nobuo Aoki
  • Patent number: 5194168
    Abstract: Lubricant compositions of high lubrication and light coloration characteristics are made up essentially of a selected mineral or synthetic oil and a selected polybutadiene. The polymeric component contains greater than 20% by mol of vinyl bonds in terms of its monomeric unit and has crosslinked more than 10% of the vinyl bond content.
    Type: Grant
    Filed: January 28, 1991
    Date of Patent: March 16, 1993
    Assignee: Nippon Oil Co., Ltd.
    Inventors: Nobuo Aoki, Shinichiro Suzuki
  • Patent number: 5153063
    Abstract: A magnetic recording medium comprising a non-magnetic support having provided thereon a magnetic layer comprising ferromagnetic fine powder uniformly dispersed in a binder, wherein the binder comprises at least one resin selected from the group consisting of a vinyl chloride resin and a urethane resin, said resin for the binder has a weight average molecular weight of about from 20,000 to 80,000 and contains a low molecular weight fraction having a weight average molecular weight of about 3,000 or less in an amount of about 3 wt. % or less based on the amount of the resin.
    Type: Grant
    Filed: August 28, 1991
    Date of Patent: October 6, 1992
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Tsutomu Okita, Kazuko Hanai, Akihiro Matsufuji, Nobuo Aoki
  • Patent number: 5118763
    Abstract: Thermosetting polymers predominantly of a polybutadiene as a base polymer is disclosed, which polybutadiene is so configured as to have a vinyl content of not less than 40% by mol of the total monomer mol and a crosslink reactivity of at least 70% of the vinyl content. The cured polymer is ultrahighly resistant to heat and particularly applicable as an engineering plastics. Also disclosed is a process for producing the thermosetting polymer with the use of a specific initiator.
    Type: Grant
    Filed: March 19, 1990
    Date of Patent: June 2, 1992
    Assignee: Nippon Oil Co., Ltd.
    Inventors: Nobuo Aoki, Toshiyuki Enomoto, Shinchiro Suzuki
  • Patent number: 5098829
    Abstract: The present invention provides a monoclonal antibody specific to a thrombin-binding substance (TM), hybridomas producing the monoclonal antibody, a purification process of TM featuring the use of the monoclonal antibody as an immunoadsorbent, as well as an immunoassay of TM featuring the use of the monoclonal antibody.
    Type: Grant
    Filed: July 30, 1990
    Date of Patent: March 24, 1992
    Assignee: Kowa Co., Ltd.
    Inventors: Nobuo Aoki, Takao Nagoya, Shigeru Kimura
  • Patent number: 5055872
    Abstract: An image recording apparatus having a lens unit and a mirror unit. The lens unit and the mirror unit are movably supported by a frame of the apparatus. A cam plate is provided at the lens unit, and a lever is in abutment with the cam plate. When the lens unit is moved in a direction, the cam plate is also moved, so that the lever is pivotally moved. The lever is abutted on the mirror unit. The pivotal motion of the lever, the mirror unit is also moved in another direction. The cam plate has a plurality of cam surfaces each defining respective copying magnifications.
    Type: Grant
    Filed: January 18, 1990
    Date of Patent: October 8, 1991
    Assignee: Brother Kogyo Kabushiki Kaisha
    Inventors: Kazuichi Sakaida, Katsuyoshi Sonobe, Nobuo Aoki, Satoshi Uchiyama, Makoto Yamada
  • Patent number: 5049926
    Abstract: An image recording apparatus for recording an image corresponding to an original on a photosensitive recording medium by irradiating light onto the original and converging light from the original onto the photosensitive recording medium. The apparatus includes a lens unit vertically movably supported by the frame, a plurality of position setting holes arrayed in a vertical direction of the frame, position setting means provided on the lens unit and capable of being inserted into one of the position setting holes for fixing the lens unit to the frame, urging means provided on the lens unit for urging the position setting means toward the frame to project the position setting means, actuating means provided on the lens unit for actuating the position setting means so that the position setting means retracts and moves away from the frame against urging force of the urging means when electric current is supplied to the actuating means.
    Type: Grant
    Filed: January 26, 1990
    Date of Patent: September 17, 1991
    Assignee: Brother Kogyo Kabushiki Kaisha
    Inventors: Michitoshi Akao, Katsuyoshi Sonobe, Kazuichi Sakaida, Nobuo Aoki, Satoshi Uchiyama, Hiroshi Igarashi
  • Patent number: 5047560
    Abstract: Highly pure 3,3',4,4'-biphenyltetracarboxylic acid (BPTA) and dianhydride thereof (BPDA) are produced by heating crude BPTA to give BPDA, treating the BPDA with hot water to give highly pure BPTA, and in the case of highly pure BPDA, heat treating the pure BPTA to give highly pure BPDA.
    Type: Grant
    Filed: March 9, 1990
    Date of Patent: September 10, 1991
    Assignees: Hitachi, Ltd., Japan Carlit Co., Ltd., Kanto Koatsu
    Inventors: Fusaji Shoji, Nobuo Aoki, Jun Kurita, Tsuyoshi Aoyama, Toshiyuki Kiriyu, Yoshinori Matsuzaki
  • Patent number: 5047503
    Abstract: Thrombin-binding substances are obtained by fractionating human urine by ion-exchange chromatography, affinity chromatography using a thrombin-bound carrier, immune adsorption column chromatography, gel filtration, and/or molecular-weight fractionation. One of the substances has a molecular weight of 46,500.+-.6,000 in reduced condition and 39,000.+-.10,000 in unreduced condition by SDS PAGE and an isoelectric point at pH 5.0-5.3, while the other has a molecular weight of 40,000.+-.8,000 in reduced condition and 31,000.+-.10,000 in unreduced condition by SDS PAGE and an isoelectric point at pH 4.9-5.7. They have strong affinity to thrombin. They are capable of promoting the thrombin catalyzed activation of protein C and prolong clotting time. They are stable to denaturing agents (urea and sodium dodecylsulfate).
    Type: Grant
    Filed: July 10, 1987
    Date of Patent: September 10, 1991
    Assignee: Kowa Company, Ltd.
    Inventors: Nobuo Aoki, Shigeru Kimura, Masami Shiratsuchi
  • Patent number: 5043425
    Abstract: Novel thrombin-binding substances (A) and (B) are disclosed. The thrombin-binding substances have the following characteristics:(a) molecular weight:Thrombin-binding substance (A):90,000-92,000 under reduced conditions55,000-58,000 under unreduced conditionsThrombin-binding substance (B):98,000-105,000 under reduced conditions60,000-65,000 under unreduced conditions(b) isoelectric point:Thrombin-binding substance (A): pH 6.0-6.8Thrombin-binding substance (B): pH 5.8-6.5(c) affinity: strong affinity to thrombin(d) activity:(1) capable of promoting the thrombin catalyzed activation of protein C(2) prolongs clotting time; and(e) stability: stable to denaturing agents (sodium dodecylsulfate and urea).The thrombin-binding substances are useful as a medicine for curing thrombosis.
    Type: Grant
    Filed: August 16, 1989
    Date of Patent: August 27, 1991
    Assignee: Kowa Co., Ltd.
    Inventors: Nobuo Aoki, Shigeru Kimura, Masami Shiratsuchi
  • Patent number: 4902614
    Abstract: A monoclonal antibody which is specific to human protein C which has calcium bound at the gammacarboxyglutamic acid(Gla) domain and does not recognize human protein C which is not bound to calcium at the Gla domain. The monoclonal antibody is used in an immunoassay method for determining human protein C having a Gla domain and in a method for recovering human protein C having a Gal domain.
    Type: Grant
    Filed: December 3, 1985
    Date of Patent: February 20, 1990
    Assignee: Teijin Limited
    Inventors: Kenji Wakabayashi, Yoshihiko Sumi, Yataro Ichikawa, Yoichi Sakata, Jun Mimuro, Nobuo Aoki
  • Patent number: 4889791
    Abstract: A positive type photoresist material comprises a polymer having structural units each represented by the following formula (I) of; ##STR1## wherein each of R.sup.1, R.sup.2, R.sup.3 and R.sup.6 represents a hydrogen atom or a hydrocarbon residue having 1 to 12 carbon atoms, each or R.sup.4 and R.sup.5 represents a hydrogen atom, a hydroxyl group or a hydrocarbon residue having 1 to 12 carbon atoms and Z represents--CH.sub.2 --.sub.n which n indicates an integer of 0 to 4.
    Type: Grant
    Filed: January 31, 1989
    Date of Patent: December 26, 1989
    Assignee: Nippon Oil Co., Ltd.
    Inventors: Shozo Tsuchiya, Nobuo Aoki, Shinichiro Suzuki
  • Patent number: 4776899
    Abstract: An improved multifilament superconductor is fabricated by the method in which a tin rod or tin based alloy rod is clad with a copper based alloy tube, the thus obtained copper-clad rod is further clad with a niobium based alloy tube, and a copper material is applied as a stabilizer on an outer peripheral surface of the niobium based alloy tube to form a composite. This composite is then reduced and thermally treated at a temperature ranging from 640.degree. to 770.degree. C. to thereby form an Nb.sub.3 Sn superconductor composite with a filament tube therein. At least one of the copper based alloy tube and the niobium based alloy tube contains 0.1-5.0 at. % titanium, and in addition, the tin based alloy rod may contain 0.1-3.5 at. % titanium. The tin is contained in the copper-clad rod at weight % of about 25-85, preferably 30-80 weight %.
    Type: Grant
    Filed: June 15, 1987
    Date of Patent: October 11, 1988
    Assignees: Kabushiki Kaisha Toshiba, Showa Electric Wire and Cable Company Limited
    Inventors: Satoru Murase, Hachio Shiraki, Eigen Suzuki, Masamitsu Ichihara, Yoshimasa Kamisada, Nobuo Aoki, Tomoyuki Kumano
  • Patent number: 4751168
    Abstract: Positive acting electron beam resist materials are described. The material comprises a polymer having fundamental units of the general formula ##STR1## in which R.sub.1, R.sub.2 and R.sub.3 independently represent hydrogen or a hydrocarbon group having from 1 to 6 carbon atoms, and R.sub.4 represents an organic residue having from 1 to 20 carbon atoms. The polymer may be used, as the resist material, as it is or by mixing with other type of resin.
    Type: Grant
    Filed: April 15, 1986
    Date of Patent: June 14, 1988
    Assignee: Nippon Oil Co., Ltd.
    Inventors: Shozo Tsuchiya, Nobuo Aoki
  • Patent number: 4748156
    Abstract: A novel thrombin-binding substance having the characteristics of (a) molecular weight: 47,000.+-.6,000 in reduced condition and 38,000.+-.6,000 in unreduced condition, (b) isoelectric point: pH 4.9-5.7, (c) affinity: strong affinity to thrombin, (d) activity: (1) capable of promoting the thrombin catalyzed activation of protein C, (2) prolongs clotting time; and (e) stability: stable to denaturing agents (urea sodium and dodecylsulfate), can be prepared from a human placenta by means of extraction, fractionation using ion exchange chromatography and affinity chromatography, and/or gel filtration, followed by electrophoresis. The substance is useful as a medicine for the treatment of thrombosis.
    Type: Grant
    Filed: January 15, 1987
    Date of Patent: May 31, 1988
    Assignee: Kowa Co., Ltd.
    Inventors: Nobuo Aoki, Masami Shiratsuchi, Shigeru Kimura
  • Patent number: H1148
    Abstract: A method of separating activated human protein C, which comprises bringing a mixture containing activated human protein C having a gamma-carboxyglutamic acid (Gla) domain in the presence of a calcium ion into contact with a fixed antibody comprising an insoluble carrier and fixed thereto an antibody to a complex of human protein C and a calcium ion bound to the Gla domain whereby the activated human protein C is captured by the fixed antibody in the form in which the calcium ion is bound to the Gla domain.
    Type: Grant
    Filed: January 3, 1992
    Date of Patent: March 2, 1993
    Inventors: Kenji Wakabayashi, Yoshihiko Sumi, Yataro Ichikawa, Yoichi Sakata, Nobuo Aoki