Patents by Inventor Norbert Hauel

Norbert Hauel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imidazo[4,5-b] and [4,5-c]pyridine derivatives having cardiotonic activity
    Patent number: 4582837
    Abstract: There are disclosed novel imidazole derivatives of the formula ##STR1## and derivatives of the formula ##STR2## the tautomers thereof, and non-toxic, pharmacologically acceptable addition salts thereof with inorganic or organic acids. The compounds described herein are useful in treating cardiac insufficiency.
    Type: Grant
    Filed: June 21, 1983
    Date of Patent: April 15, 1986
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Norbert Hauel, Volkhard Austel, Joachim Heider, Manfred Reiffen, Willi Diederen
  • 2-Phenyl-imidazo[4,5-c]pyridinones useful as cardiotonic agents
    Patent number: 4568680
    Abstract: Compounds of the formula ##STR1## wherein one of A and B is methenyl (--CH.dbd.) and the other is carbonyl; R.sub.1 is (alkyl of 1 to 3 carbon atoms)mercapto, (alkyl of 1 to 3 carbon atoms)sulfinyl or (alkyl of 1 to 3 carbon atoms)sulfonyl; andR.sub.2 is alkoxy of 1 to 3 carbon atoms;tautomers thereof, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds are useful as cardiotonics.
    Type: Grant
    Filed: December 5, 1984
    Date of Patent: February 4, 1986
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Volkhard Austel, Norbert Hauel, Joachim Heider, Manfred Reiffen, Jacobus C. A. Van Meel, Willi Diederen
  • Benzazepine derivatives, their pharmaceutical compositions and method of use
    Patent number: 4490369
    Abstract: Compounds of the formula ##STR1## wherein A is --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH--, --NH--CO--, --CH.sub.2 --CO-- or ##STR2## where R.sub.7 is alkyl of 1 to 3 carbon atoms, andB is methylene, carbonyl or thiocarbonyl, orA is --CO--CO--, --N.dbd.CH--, ##STR3## where R.sub.8 is hydrogen or alkyl of 1 to 3 carbon atoms substituted by a phenyl, methoxyphenyl or dimethoxyphenyl, andB is methylene;E is n-alkylene of 2 to 4 carbon atoms optionally substituted by an alkyl of 1 to 3 carbon atoms, 2-hydroxy-n-propylene, 2-hydroxy-n-butylene or 3-hydroxy-n-butylene;G is n-alkylene of 1 to 5 carbon atoms optionally substituted by an alkyl of 1 to 3 carbon atoms, wherein one methylene group of an n-alkylene of 2 to 5 carbon atoms can be replaced by a carbonyl group, with the proviso that B represents a methylene or carbonyl group, or methylene-n-hydroxy-alkylene of 1 to 4 carbon atoms, where the methylene group is attached to the nitrogen atom; andR.sub.1 to R.sub.
    Type: Grant
    Filed: November 2, 1983
    Date of Patent: December 25, 1984
    Assignee: Dr. Karl Thomae Gesellschaft mit beschrankter Haftung
    Inventors: Manfred Reiffen, Joachim Heider, Norbert Hauel, Volkhard Austel, Wolfgang Eberlein, Walter Kobinger, Christian Lillie, Klaus Noll, Helmut Pieper, Gerd Kruger, Johannes Keck