Abstract: The present invention provides a method for testing strength of a metal roofing material, the metal roofing material comprising: a front substrate made of a metal sheet; a back substrate arranged on the back side of the front substrate; and a core material filled between the front substrate and the back substrate, the method comprising the steps of: tightening the metal roofing material 1 to a base 50; and applying a load 52L for uplifting an end portion 1E of the metal roofing material 1 tightened to the base 50 to the end portion 1E and measuring an uplift amount of the end portion 1E corresponding to the load 52L.

Abstract: A metallic roof material 1 according to the present invention comprises: a front substrate 10 made of a metal sheet, the front substrate 10 comprising a body portion 100 formed into a box shape; a back substrate 11 arranged on a back side of the front substrate 10 so as to cover an opening of the body portion 100; and a core material 12 filled between the body portion 100 and the back substrate 11, the metallic roof material 1 being tightened to a roof base by driving at least one tightening member into the body portion 100, wherein a top plate portion 101 of the body portion 100 comprises at least one protruding rib 3 comprised of at least one protrusion 30 disposed along a side of a polygon or along a circle, and wherein the metallic roof material 1 is configured such that the tightening member is driven into an inner region 3a of the protruding rib 3.

Abstract: A lithium-ion secondary-battery case that allows bonding without weld spatter and has high strength against external force acting on the battery case, and a method for manufacturing the lithium-ion secondary-battery case are provided. Specifically, an austenitic stainless steel foil is used for a cup component (2), and a two-phase stainless steel having an austenite transformation start temperature AC1 in a temperature increase process at 650° C. to 950° C. and an austenite and ferrite two-phase temperature range of 880° C. and higher, is used for a cover component (3), and the diffusion bonding is proceeded while accompanied by grain boundary movement upon transformation of the two-phase steel from a ferrite phase into an austenite phase within a heating temperature range of 880° C. to 1080° C.

Abstract: The present invention relates to a metal roofing material 1 that is arranged on an eave-side metal roofing material in an eave-ridge direction 6 of a roof so as to overlap the metal roofing material and the eave-side metal roofing material. The metal roofing material includes a front substrate 2 made of a metal sheet and including a body portion 20 formed in a box shape; a back substrate 3 arranged on the back side of the front substrate 2 so as to cover an opening of the body portion 20; a core material 4 filled between the body portion 20 and the back substrate 3; and at least one plate reinforcing member 5 that is embedded in the core material 4 at a position closer to the back substrate 3 than a top plate of the body portion 20 or that is disposed in contact with the outer surface of the back substrate 3.

Abstract: A metallic roof material 1 according to the present invention comprises: a front substrate 10 made of a metal sheet, the front substrate 10 comprising a body portion 100 formed into a box shape; a back substrate 11 arranged on a back side of the front substrate 10 so as to cover an opening of the body portion 100; and a core material 12 filled between the body portion 100 and the back substrate 11, the metallic roof material 1 being tightened to a roof base by driving at least one tightening member into the body portion 100, wherein a top plate portion 101 of the body portion 100 comprises at least one protruding rib 3 comprised of at least one protrusion 30 disposed along a side of a polygon or along a circle, and wherein the metallic roof material 1 is configured such that the tightening member is driven into an inner region 3a of the protruding rib 3.

Abstract: A body portion 100 of a front substrate 10 includes first side surfaces 105 and second side surfaces 106, each of the second side surfaces 106 being arranged at a position protruding toward the outer side along a width direction 100a than the first side surface 105. Each of the first side surfaces 105 includes a side flange 105a. A protruding width of the side flange 105a from the first side surface 105 is equal to or less than a protruding width of the second side surface 106 from the first side surface 105. A metal roofing member 1 is arranged on a roof base while abutting at least the second side surface 106 against a second side surface of other metal roofing member.

Abstract: A metal roofing member 1 is disposed side by side with another metal roofing member on a roof base. The metal roofing member 1 has a box-shaped front substrate 10 made of a metal sheet, a rear substrate 11 disposed on the rear side of the front substrate 10, so as to cover an opening of the front substrate 10, and a core material 12 made from a foam resin and filled in between the front substrate 10 and the rear substrate 11. The front substrate 10 results from forming the metal sheet into a box shape. The front substrate 10 has a side wall portion that is continuous in the circumferential direction and is formed by performing drawing or bulging processing on the metal sheet. The front substrate 10 has a height of 4 mm to 8 mm.

Abstract: A body portion 100 of a front substrate 10 includes first side surfaces 105 and second side surfaces 106, each of the second side surfaces 106 being arranged at a position protruding toward the outer side along a width direction 100a than the first side surface 105. Each of the first side surfaces 105 includes a side flange 105a. A protruding width of the side flange 105a from the first side surface 105 is equal to or less than a protruding width of the second side surface 106 from the first side surface 105. A metal roofing member 1 is arranged on a roof base while abutting at least the second side surface 106 against a second side surface of other metal roofing member.

Abstract: The present invention relates to a metal roofing material 1 that is arranged on an eave-side metal roofing material in an eave-ridge direction 6 of a roof so as to overlap the metal roofing material and the eave-side metal roofing material. The metal roofing material includes a front substrate 2 made of a metal sheet and including a body portion 20 formed in a box shape; a back substrate 3 arranged on the back side of the front substrate 2 so as to cover an opening of the body portion 20; a core material 4 filled between the body portion 20 and the back substrate 3; and at least one plate reinforcing member 5 that is embedded in the core material 4 at a position closer to the back substrate 3 than a top plate of the body portion 20 or that is disposed in contact with the outer surface of the back substrate 3.

Abstract: Disclosed is a novel process for producing a Muse cell-like cell or a novel method for extending the replicative life span of a cell population. Provided is a process for producing a Muse cell-like cell, comprising the step of inhibiting the expression or function of ELAVL2, TEAD1, or GATAD2B. At this time, siRNA or shRNA may be used to inhibit the expression or function of ELAVL2, TEAD1, or GATAD2B.

Abstract: The present invention provides a method for testing strength of a metal roofing material, the metal roofing material comprising: a front substrate made of a metal sheet; a back substrate arranged on the back side of the front substrate; and a core material filled between the front substrate and the back substrate, the method comprising the steps of: tightening the metal roofing material 1 to a base 50; and applying a load 52L for uplifting an end portion 1E of the metal roofing material 1 tightened to the base 50 to the end portion 1E and measuring an uplift amount of the end portion 1E corresponding to the load 52L.

Abstract: A metal roofing member 1 has a front substrate 10, a rear substrate 11 and a core material 12. The front substrate 10 is made of a metal sheet. In the front substrate 10, a box-shaped body portion 100 and a flange portion 110 extending from the body portion 100 are provided. The flange portion 110 is formed by folding back, over the rear side of the front substrate 10, of a metal sheet 111 extending outwards of the body portion 100 in a direction 100b perpendicular to a height direction 100a of the body portion 100, from a lower edge of the body portion 100, in such a manner that the metal sheet 111 wraps around the rear substrate 11. The metal roofing member 1 is disposed on a roof base, with the flange portion 110 butting against a flange portion 110 of another metal roofing member.

Abstract: The purpose of the present invention is to obtain novel therapeutic drugs for malignant tumors, methods for producing a stem cell, or DNA damage-ameliorating agents, etc., wherein a HAT1 and KAT8 inhibitor is used; a kit containing a HAT1 inhibitor and a KAT8 inhibitor may be used; a composition comprising a HAT1 inhibitor, wherein the HAT1 inhibitor is used in combination with a KAT8 inhibitor, may be used; or a composition comprising a KAT8 inhibitor, wherein the KAT8 inhibitor is used in combination with a HAT1 inhibitor, may be used.

Abstract: The purpose of the present invention is to obtain a novel and effective composition for ameliorating DNA damage. Used is a composition for ameliorating DNA damage, comprising a polynucleotide comprising: a nucleotide sequence set forth in SEQ ID NO: 1; or a nucleotide sequence having 1 to 3 nucleotide deletions, substitutions, insertions, or additions in the nucleotide sequence set forth in SEQ ID NO: 1. Also used is a composition for ameliorating DNA damage, comprising a vector encoding a polynucleotide comprising: a nucleotide sequence set forth in SEQ ID NO: 1; or a nucleotide sequence having 1 to 3 nucleotide deletions, substitutions, insertions, or additions in the nucleotide sequence set forth in SEQ ID NO: 1.

Abstract: A metal roofing member 1 has a front substrate 10, a rear substrate 11 and a core material 12. The front substrate 10 is made of a metal sheet. In the front substrate 10, a box-shaped body portion 100 and a flange portion 110 extending from the body portion 100 are provided. The flange portion 110 is formed by folding back, over the rear side of the front substrate 10, of a metal sheet 111 extending outwards of the body portion 100 in a direction 100b perpendicular to a height direction 100a of the body portion 100, from a lower edge of the body portion 100, in such a manner that the metal sheet 111 wraps around the rear substrate 11. The metal roofing member 1 is disposed on a roof base, with the flange portion 110 butting against a flange portion 110 of another metal roofing member.

Abstract: A metal roofing member 1 is disposed side by side with another metal roofing member on a roof base. The metal roofing member 1 has a box-shaped front substrate 10 made of a metal sheet, a rear substrate 11 disposed on the rear side of the front substrate 10, so as to cover an opening of the front substrate 10, and a core material 12 made from a foam resin and filled in between the front substrate 10 and the rear substrate 11. The front substrate 10 results from forming the metal sheet into a box shape. The front substrate 10 has a side wall portion that is continuous in the circumferential direction and is formed by performing drawing or bulging processing on the metal sheet. The front substrate 10 has a height of 4 mm to 8 mm.

Abstract: An austenitic stainless steel foil 2 with a thickness equal to or less than 300 ?m is disposed to face a punch 12, and the stainless steel foil 2 is subjected to drawing in a state in which an annular region 2a of the stainless steel foil 2 that is in contact with a shoulder portion 12d of the punch 12 is set to a temperature up to 30° C. and an external region 2b outside the annular region 2a is set to a temperature of from 40° C. to 100° C.

Abstract: An austenitic stainless steel foil 2 with a thickness equal to or less than 300 ?m is disposed to face a punch 12, and the stainless steel foil 2 is subjected to drawing in a state in which an annular region 2a of the stainless steel foil 2 that is in contact with a shoulder portion 12d of the punch 12 is set to a temperature up to 30° C. and an external region 2b outside the annular region 2a is set to a temperature of from 40° C. to 100° C.

Abstract: A novel compound to induce a pluripotent stem cell is provided. A novel anti-malignant-tumor substance is provided. A pluripotent stem cell-inducing agent, including a single-stranded or double-stranded polynucleotide containing the base sequence shown in SEQ ID NO:41 or a base sequence including deletion, substitution, or addition of 1 to 3 bases in SEQ ID No: 41, in which the pluripotent stem cell-inducing agent induces a cell to become a pluripotent stem cell is provided.

Abstract: A lithium-ion secondary-battery case that allows bonding without weld spatter and has high strength against external force acting on the battery case, and a method for manufacturing the lithium-ion secondary-battery case are provided. Specifically, an austenitic stainless steel foil is used for a cup component (2), and a two-phase stainless steel having an austenite transformation start temperature AC1 in a temperature increase process at 650° C. to 950° C. and an austenite and ferrite two-phase temperature range of 880° C. and higher, is used for a cover component (3), and the diffusion bonding is proceeded while accompanied by grain boundary movement upon transformation of the two-phase steel from a ferrite phase into an austenite phase within a heating temperature range of 880° C. to 1080° C.