Patents by Inventor Noubar B. Afeyan

Noubar B. Afeyan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190247440
    Abstract: Provided are cells containing exogenous antigen and uses thereof.
    Type: Application
    Filed: April 12, 2019
    Publication date: August 15, 2019
    Inventors: Jordi Mata-Fink, John Round, Noubar B. Afeyan, Avak Kahvejian
  • Publication number: 20190240293
    Abstract: Described herein are methods for treating a subject having or at risk of developing cancer administering a neuromodulating agent.
    Type: Application
    Filed: July 25, 2017
    Publication date: August 8, 2019
    Inventors: Erica WEINSTEIN, Jordi MATA-FINK, Avak KAHVEJIAN, Noubar B. AFEYAN, Laura Kristina JEANBART, Alexandra LANTERMANN, Jonathan Barry HUROV, Manuel Andreas FANKHAUSER, Chengyi J. SHU, Eric Franklin ZHU
  • Patent number: 10344263
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: July 9, 2019
    Assignee: RUBIUS THERAPEUTICS, INC.
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • Publication number: 20190192581
    Abstract: Methods and compositions for populating the gastrointestinal tract of a subject are described. Methods include administering to a subject a therapeutic composition comprising a purified population of spore-forming bacteria produced by providing a fecal material and subjecting the material to a treatment step resulting in purification of spore-form ing bacteria. Methods include administering an amount effective to engraft and/or augment in the gastrointestinal tract in order to treat or prevent a dysbiosis in the mammalian subject.
    Type: Application
    Filed: August 1, 2018
    Publication date: June 27, 2019
    Inventors: Geoffrey von Maltzahn, Matthew R. Henn, David N. Cook, David Arthur Berry, Noubar B. Afeyan, Brian Goodman, Mary-Jane Lombardo McKenzie, Marin Vulic
  • Patent number: 10329531
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: June 25, 2019
    Assignee: RUBIUS THERAPEUTICS, INC.
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • Patent number: 10301594
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: May 28, 2019
    Assignee: RUBIUS THERAPEUTICS, INC
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • Patent number: 10301593
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: May 28, 2019
    Assignee: RUBIUS THERAPEUTICS, INC.
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • Publication number: 20190144827
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Application
    Filed: November 19, 2018
    Publication date: May 16, 2019
    Applicant: RUBIUS THERAPEUTICS, INC.
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • Patent number: 10258655
    Abstract: Provided are therapeutic compositions containing microbial populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: April 16, 2019
    Assignee: Seres Therapeutics, Inc.
    Inventors: Matthew R. Henn, Kevin Daniel Litcofsky, Anthony Mario D'Onofrio, Toshiro K. Ohsumi, Mary-Jane Lombardo McKenzie, Geoffrey von Maltzahn, David N. Cook, David Arthur Berry, Noubar B. Afeyan, John Grant Aunins
  • Patent number: 10253296
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: April 9, 2019
    Assignee: RUBIUS THERAPEUTICS, INC.
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • Publication number: 20190083540
    Abstract: The invention includes compositions and methods related to multimodal therapies, e.g., for treating a cancer. A multimodal therapy described herein provides and/or administers a plurality of agents that function in a coordinated manner to provide a therapeutic benefit to a subject in need thereof, e.g., a subject having a cancer.
    Type: Application
    Filed: December 3, 2018
    Publication date: March 21, 2019
    Inventors: Avak Kahvejian, Jordi Mata-Fink, Robert J. Deans, Tiffany F. Chen, John Round, Noubar B. Afeyan, Torben Straight Nissen, Nathan Dowden, Tom Wickham, Sivan Elloul
  • Publication number: 20190030129
    Abstract: Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the use of modified messenger RNAs, and are useful to treat or prevent diseases, disorders or conditions, or to improve a subject's heath or wellbeing.
    Type: Application
    Filed: March 7, 2018
    Publication date: January 31, 2019
    Inventors: Jason P. SCHRUM, Stephane BANCEL, Noubar B. AFEYAN, Kenechi EJEBE
  • Patent number: 10155029
    Abstract: The invention relates to compositions and methods for the manufacture and optimization of modified mRNA molecules via optimization of their terminal architecture.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: December 18, 2018
    Assignee: ModernaTX, Inc.
    Inventors: Tirtha Chakraborty, Stephane Bancel, Stephen G. Hoge, Atanu Roy, Antonin De Fougerolles, Noubar B. Afeyan
  • Publication number: 20180271910
    Abstract: Provided are cells containing exogenous antigen and uses thereof.
    Type: Application
    Filed: March 5, 2018
    Publication date: September 27, 2018
    Inventors: Jordi Mata-Fink, John Round, Noubar B. Afeyan, Avak Kahvejian
  • Publication number: 20180265847
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Application
    Filed: March 29, 2018
    Publication date: September 20, 2018
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • Patent number: 10064900
    Abstract: Methods and compositions for populating the gastrointestinal tract of a subject are described. Methods include administering to a subject a therapeutic composition comprising a purified population of spore-forming bacteria produced by providing a fecal material and subjecting the material to a treatment step resulting in purification of spore-forming bacteria. Methods include administering an amount effective to engraft and/or augment in the gastrointestinal tract in order to treat or prevent a dysbiosis in the mammalian subject.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: September 4, 2018
    Assignee: Seres Therapeutics, Inc.
    Inventors: Geoffrey Von Maltzahn, Matthew R. Henn, David N. Cook, David Arthur Berry, Noubar B. Afeyan, Brian Goodman, Mary-Jane Lombardo McKenzie, Marin Vulic
  • Publication number: 20180214579
    Abstract: The present invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides formulations containing amino acids.
    Type: Application
    Filed: March 26, 2018
    Publication date: August 2, 2018
    Inventors: Örn ALMARSSON, Noubar B. AFEYAN, Joseph Beene BOLEN, Staci SABNIS
  • Publication number: 20180216067
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Application
    Filed: March 29, 2018
    Publication date: August 2, 2018
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • Publication number: 20180208897
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Application
    Filed: March 19, 2018
    Publication date: July 26, 2018
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • Publication number: 20180193385
    Abstract: The invention includes compositions and methods related to multimodal therapies, e.g., for treating a cancer. A multimodal therapy described herein provides and/or administers a plurality of agents that function in a coordinated manner to provide a therapeutic benefit to a subject in need thereof, e.g., a subject having a cancer.
    Type: Application
    Filed: February 27, 2018
    Publication date: July 12, 2018
    Inventors: Avak Kahvejian, Jordi Mata-Fink, Robert J. Deans, Tiffany F. Chen, John Round, Noubar B. Afeyan, Torben Straight Nissen, Nathan Dowden, Tom Wickham, Sivan Elloul