Abstract: A medical system for repairing a mitral valve comprising a catheter (5) with a temporary valve (10), a commissure locator device (20), wherein the commissure locator device and the temporary valve are connected, and an annuloplasty implant (30).

Abstract: An annuloplasty implant comprising an inner core of a shape memory material, an outer covering arranged radially outside said inner core material to cover at least part of said inner core, wherein said outer covering is resilient to conform to said inner core during movement of said shape memory material, wherein said outer covering comprises a material having surface properties to promote endothelialization. Two portions of the implant may be joined by a recess to be flexible with respect to each other by a bending motion at the recess. The two portions may also have a predefined breaking point at the recess.

Abstract: An annuloplasty device is disclosed for treating a defective mitral valve having an annulus, comprising a removable and flexible elongate displacement unit for temporary insertion into a coronary sinus (CS) adjacent the valve, wherein the displacement unit has a delivery state for delivery into the CS, and an activated state to which the displacement unit is temporarily and reversibly transferable from said delivery state, the displacement unit comprises a proximal reversibly expandable portion, a distal anchoring portion being movable in relation to the proximal expandable portion in a longitudinal direction of the displacement unit to said activated state in which the shape of the annulus is modified to a modified shape, wherein the proximal expandable portion is reversibly foldable to an expanded state for positioning against a tissue wall at the entrance of the CS, and wherein the distal anchoring portion comprises an inflatable unit.

Abstract: A device for improving the function of a heart valve has a first and a second shape. The device comprises two contact points, wherein the device in the first shape exhibits a distance between the two contact points essentially corresponding to a distance between two commissures of the heart valve and the device in the second shape exhibits an increased distance between the contact points. The device is in the first shape arranged for insertion to the heart valve to establish a contact between the contact points and the commissures. The device is transferable from said first shape to said second shape, and the device is in the second shape arranged for extending in abutment with valve tissue throughout a cycle of heart action. The device may change the shape of the heart valve by stretching it between the commissures for improving the ability of the heart valve to close.

Abstract: An annuloplasty implant (100) is disclosed comprising first and second support rings (101, 102) arranged in a coiled configuration around an axial direction (103), and being adapted to be arranged on opposite sides of native heart valve leaflets to pinch said leaflets. At least part of said first and second support ring is formed from a carbon fiber material (105). The first and second support rings are resiliently movable with respect to each other in opposite directions along said axial direction. A method of manufacturing an annuloplasty implant is also disclosed.

Abstract: A method of repairing a defective heart valve is disclosed comprising directing an implant delivery catheter to form a first curve of the implant delivery catheter around chordae of the heart valve on a ventricular side of the heart valve, inserting the implant delivery catheter through the heart valve to an atrial side thereof, forming a second curve of the delivery catheter along an annulus of the heart valve on the atrial side, and ejecting an annuloplasty implant from the delivery catheter while retracting the delivery catheter such that the annuloplasty implant is arranged along the first and second curve on the ventricular and atrial side.

Abstract: An annuloplasty device for repairing a heart valve comprises a first and a second support member that overlap each other and form a scissor linkage. The first and second support members are configured to pinch leaflets of the heart valve.

Abstract: A device for improving the function of a heart valve comprises a first loop-shaped support, which is configured to abut a first side of the heart valve, and a first flange unit being connected to said first loop-shaped support. The flange unit is configured to be arranged against said annulus when said first loop-shaped support is abutting said heart valve.

Abstract: A medical system is disclosed for treating a defective mitral valve (MV) having an annulus (A). The system has a removable and flexible elongate displacement unit for temporary insertion into a coronary sinus (CS) adjacent the valve, wherein the displacement unit has a delivery state for delivery into said CS, and an activated state to which the displacement unit is temporarily and reversibly transferable from the delivery state. The displacement unit has a proximal reversibly expandable portion, a distal anchoring portion being movable in relation to the proximal expandable portion in a longitudinal direction of the displacement unit to the activated state in which the shape of the annulus is modified to a modified shape (A?); and an annuloplasty device for permanent fixation at the mitral valve annulus by annuloplasty of the valve when the modified shape is obtained.

Abstract: A device for improving the function of a heart valve comprises a first loop-shaped support, which is configured to abut a first side of the heart valve. A first flange unit is may be configured as a fabric sleeve covering the loop-shaped support. A portion of the fabric sleeve forms a flange that is attached to the annulus when said first loop-shaped support is abutting said heart valve. The flange is provideable by folding at least a portion of said sleeve over itself for forming a double layer of opposing fabrics thereof, such that said sleeve comprises a flange portion extending from said first loop-shaped support configured to overlap a surface of and form a collar around, at least a portion of said annulus.

Abstract: A device for improving the function of a heart valve comprises a first loop-shaped support, which is configured to abut a first side of the heart valve, and a first flange unit being connected to said first loop-shaped support. The flange unit is configured to be arranged against said annulus when said first loop-shaped support is abutting said heart valve.

Abstract: A method of repairing a defective heart valve is disclosed comprising directing an implant delivery catheter to form a first curve of the implant delivery catheter around chordae of the heart valve on a ventricular side of the heart valve, inserting the implant delivery catheter through the heart valve to an atrial side thereof, forming a second curve of the delivery catheter along an annulus of the heart valve on the atrial side, and ejecting an annuloplasty implant from the delivery catheter while retracting the delivery catheter such that the annuloplasty implant is arranged along the first and second curve on the ventricular and atrial side.

Abstract: An annuloplasty implant is disclosed comprising first and second support members having a coiled configuration in which the first and second support members are arranged as a coil, with two free ends, around a central axis, wherein, in said coiled configuration, said two free ends are displaced from each other with a peripheral off-set distance extending in a coil plane, said coil plane being substantially parallel to an annular periphery of said coil and perpendicular to said central axis, wherein the first and second support members and the respective free ends are configured to be arranged on opposite sides of native heart valve leaflets of a heart valve. A method of implanting an annuloplasty implant at a target site in the heart is also disclosed.

Abstract: A medical system for treating a defective mitral valve (MV) having an annulus (A). The system has a removable and flexible elongate displacement unit for temporary insertion into a coronary sinus (CS) adjacent the valve, wherein the displacement unit has a delivery state for delivery into said CS, and an activated state to which the displacement unit is temporarily and reversibly transferable from the delivery state. The displacement unit has a proximal reversibly expandable portion, a distal anchoring portion being movable in relation to the proximal expandable portion in a longitudinal direction of the displacement unit to the activated state in which the shape of the annulus is modified to a modified shape (A?); and an annuloplasty device for permanent fixation at the mitral valve annulus by annuloplasty of the valve when the modified shape is obtained.

Abstract: An annuloplasty device is disclosed comprising first and second support rings being configured to be arranged as a coil in a first configuration around an axial direction, wherein the first and second support rings are configured to be arranged on opposite sides of native heart valve leaflets of a heart valve, a stiffening unit, wherein at least part of the first and second support rings comprises an interior channel configured to receive the stiffening unit, wherein insertion of the stiffening unit into the interior channel increases the stiffness of the first and/or second support rings. A method of repairing a defective heart valve is also disclosed.

Abstract: The present disclosure relates to an arrangement, a loop-shaped support, a prosthetic heart valve and a method of repairing or replacing a native heart valve. With the method or the arrangement, leakage or regurgitation between a prosthetic heart valve and the surrounding valve tissue is prevented. In one embodiment, an arrangement for replacement or repair of a native heart valve is provided, which comprises a loop-shaped support 41 and a prosthetic heart valve 70 and wherein an outer segment 32 of the loop-shaped support 41 is positionable towards surrounding valve tissue of a native heart valve and wherein an outer surface 74 of the prosthetic heart valve 70 is positionable towards an inner segment 34 of the loop-shaped support 41 so as to prevent paravalvular leakage or regurgitation between the prosthetic heart valve 70 and the surrounding valve tissue of the native heart valve.

Abstract: A medical device is disclosed that reinforces weakened or degenerated areas of at least a portion of a leaflet (24) Of the heart valve. Function of a heart valve is thus improved. The medical device comprises at least a first partly flexible leaflet reinforcement patch (30) having an extension between an inner section (34) and an outer section (32), wherein said outer section (32) is configured to be oriented towards said annulus,and said inner section (34) is configured to be oriented towards said inner section of said valve tissue, and at least a portion of said inner section (34) of said flexible leaflet reinforcement patch (32) having at least one of said plurality of leaflets (24) in juxtaposition to said portion of said inner section (34), and said portion of said inner section (34) being positioned to provide reinforcement to said plurality of leaflets (24).

Abstract: A delivery system and method for delivery of an annuloplasty implant for a patient are disclosed. The delivery system comprises a commissure locator device for locating a commissure, comprising; an extension member, a catheter, and wherein the extension member is extendable relative the catheter for location of at least one commissure of a cardiac valve, and a coronary sinus contractor for temporary insertion into the coronary sinus (CS) and having a displacement unit being temporarily transferable to an activated state in Which the shape of the annulus Of the heart valve is modified to a modified shape to be retained by said annuloplasty implant.

Abstract: A device for improving the function of a heart valve has a first and a second shape. The device comprises two contact points, wherein the device in the first shape exhibits a distance between the two contact points essentially corresponding to a distance between two commissures of the heart valve and the device in the second shape exhibits an increased distance between the contact points. The device is in the first shape arranged for insertion to the heart valve to establish a contact between the contact points and the commissures. The device is transferable from said first shape to said second shape, and the device is in the second shape arranged for extending in abutment with valve tissue throughout a cycle of heart action. The device may change the shape of the heart valve by stretching it between the commissures for improving the ability of the heart valve to close.

Abstract: A medical securing device for securing an implant device, such as a cardiac implant device with a securing member into a tissue, such an annulus of a heart valve comprises a first elongated stem having proximal and distal ends. The distal end of the first stem has a receiving member for receiving the securing member. During a mutual movement of the distal end of the first stem and the receiving member, the distal end of the first stem is configured to introduce with the receiving member the securing member to the implant device to secure the implant device to the tissue with the securing member.