Patents by Inventor Omar KHDOUR

Omar KHDOUR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1H-pyrrolo [2, 3 -B] pyridine derivatives and their use as radical quenchers
    Patent number: 9440967
    Abstract: The present disclosure provides biologically active compounds of formula (I): and pharmaceutically acceptable salts thereof, compositions comprising these compounds, and methods of using these compounds in a variety of applications, such as treatment or suppression of diseases associated with decreased mitochondrial function resulting in diminished ATP production and/or oxidative stress and/or lipid peroxidation.
    Type: Grant
    Filed: February 11, 2013
    Date of Patent: September 13, 2016
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Sidney Hecht, Xiaoqing Cai, Omar Khdour, Jose I. Armendariz Guajardo
  • Multifunctional radical quenchers for the treatment of mitochondrial dysfunction
    Patent number: 9388163
    Abstract: The present disclosure provides methods for identifying therapeutic agents that are multifunctional radical quenchers. It also provides compounds of formula: and pharmaceutically acceptable salts thereof, compositions comprising these compounds, and methods of using these compounds in a variety of applications, such as treatment or suppression of diseases associated with decreased mitochondrial function resulting in diminished ATP production and/or oxidative stress and/or lipid peroxidation.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: July 12, 2016
    Assignee: Arizona Board of Regents, a Body Corporate of the State of Arizona, Acting for and on Behalf of Arizona State University
    Inventors: Sidney Hecht, Omar Khdour, Sandipan Roy Chowdhury, Poulami Talukder
  • Multifunctional radical quenchers for the treatment of mitochondrial dysfunction
    Patent number: 9334250
    Abstract: The present disclosure provides compounds of formula (I): compositions comprising these compounds, and methods of using these compounds in a variety of applications, such as treatment or suppression of diseases associated with decreased mitochondrial function resulting in diminished ATP production and/or oxidative stress and/or lipid peroxidation.
    Type: Grant
    Filed: October 2, 2013
    Date of Patent: May 10, 2016
    Assignee: Arizona Board of Regents, A Body Corporate of the State of Arizona Acting For and on Behalf of Arizona State University
    Inventors: Sandipan Roy Chowdhury, Omar Khdour, Sidney Hecht
  • MULTIFUNCTIONAL RADICAL QUENCHERS
    Publication number: 20150274628
    Abstract: The invention provides a compound of formula (I): [insert formula (I)] wherein X, Y, and R1-R4 have any of the values defined in the specification, and salts thereof, as well as compositions comprising the compounds or salts. The compounds are useful for treating diseases associated with impaired mitochondrial function in an animal.
    Type: Application
    Filed: October 10, 2013
    Publication date: October 1, 2015
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Manikandadas Mathilakathu Madathil, Omar Khdour, Sidney Hecht
  • Multifunctional Radical Quenchers For The Treatment Of Mitochondrial Dysfunction
    Publication number: 20150266851
    Abstract: The present disclosure provides methods for identifying therapeutic agents that are multifunctional radical quenchers. It also provides compounds of formula (I), (II), or (II-A): and pharmaceutically acceptable salts thereof, compositions comprising these compounds, and methods of using these compounds in a variety of applications, such as treatment or suppression of diseases associated with decreased mitochondrial function resulting in diminished ATP production and/or oxidative stress and/or lipid peroxidation.
    Type: Application
    Filed: June 5, 2015
    Publication date: September 24, 2015
    Inventors: Sidney Hecht, Omar Khdour, Sandipan Roy Chowdhury, Poulami Talukder
  • Multifunctional Radical Quenchers for the Treatment of Mitochondrial Dysfunction
    Publication number: 20150259309
    Abstract: The present disclosure provides compounds of formula (I): compositions comprising these compounds, and methods of using these compounds in a variety of applications, such as treatment or suppression of diseases associated with decreased mitochondrial function resulting in diminished ATP production and/or oxidative stress and/or lipid peroxidation.
    Type: Application
    Filed: October 2, 2013
    Publication date: September 17, 2015
    Inventors: Sandipan Roy Chowdhury, Omar Khdour, Sidney Hecht
  • Multifunctional radical quenchers for the treatment of mitochondrial dysfunction
    Patent number: 9102626
    Abstract: The present disclosure provides methods for identifying therapeutic agents that are multifunctional radical quenchers. It also provides compounds of formula (I), (II), or (II-A): and pharmaceutically acceptable salts thereof, compositions comprising these compounds, and methods of using these compounds in a variety of applications, such as treatment or suppression of diseases associated with decreased mitochondrial function resulting in diminished ATP production and/or oxidative stress and/or lipid peroxidation.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: August 11, 2015
    Assignee: Arizona Board of Regents, a Body Corporate of the State of Arizona
    Inventors: Sidney Hecht, Omar Khdour, Sandipan Roy Chowdhury, Poulami Talukder
  • Multifunctional radical quenchers and their uses
    Patent number: 8952025
    Abstract: The present disclosure provides biologically active compounds of formula (I): and pharmaceutically acceptable salts thereof: compositions comprising these compounds, and methods of using these compounds in a variety of applications, such as treatment or suppression of diseases associated with decreased mitochondrial function resulting in diminished ATP production and/or oxidative stress and/or lipid peroxidation.
    Type: Grant
    Filed: April 2, 2013
    Date of Patent: February 10, 2015
    Assignee: Arizona Board of Regents, A Body Corporate of the State of Arizona Acting for and on Behalf of Arizona State University
    Inventors: Sidney Hecht, Omar Khdour, Jun Lu, Pablo Arce
  • 1H-Pyrrolo [2, 3 -B] Pyridine Derivatives and Their Use as Radical Quenchers
    Publication number: 20150011580
    Abstract: The present disclosure provides biologically active compounds of formula (I): and pharmaceutically acceptable salts thereof, compositions comprising these compounds, and methods of using these compounds in a variety of applications, such as treatment or suppression of diseases associated with decreased mitochondrial function resulting in diminished ATP production and/or oxidative stress and/or lipid peroxidation.
    Type: Application
    Filed: February 11, 2013
    Publication date: January 8, 2015
    Applicant: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF
    Inventors: Jose I. Armendariz Guajardo, Sidney Hecht, Omar Khdour, Xiaoqing Cai
  • Multifunctional Radical Quenchers For The Treatment Of Mitochondrial Dysfunction
    Publication number: 20140038963
    Abstract: The present disclosure provides methods for identifying therapeutic agents that are multifunctional radical quenchers. It also provides compounds of formula (I), (II), or (II-A): and pharmaceutically acceptable salts thereof, compositions comprising these compounds, and methods of using these compounds in a variety of applications, such as treatment or suppression of diseases associated with decreased mitochondrial function resulting in diminished ATP production and/or oxidative stress and/or lipid peroxidation.
    Type: Application
    Filed: April 4, 2012
    Publication date: February 6, 2014
    Inventors: Sidney Hecht, Omar Khdour, Sandipan Roy Chowdhury, Poulami Talukder
  • Multifunctional Radical Quenchers and Their Uses
    Publication number: 20130267546
    Abstract: The present disclosure provides biologically active compounds of formula (I): and pharmaceutically acceptable salts thereof: compositions comprising these compounds, and methods of using these compounds in a variety of applications, such as treatment or suppression of diseases associated with decreased mitochondrial function resulting in diminished ATP production and/or oxidative stress and/or lipid peroxidation.
    Type: Application
    Filed: April 2, 2013
    Publication date: October 10, 2013
    Applicant: Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Ari
    Inventors: Sidney HECHT, Omar KHDOUR, Jun LU, Pablo ARCE