Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-? or combinations thereof.

Abstract: A computer system may include a keyboard housing that is capable of being moved at least partially into or out of a chassis. The chassis is associated with a transducer and an air chamber. Movement of the keyboard housing may cause size of the air chamber to be adjusted. When the size of the air chamber is increased, the transducer becomes more sensitive to sound in lower frequency ranges.

Abstract: In one embodiment, the present invention describes the synthesis of (4-bromophenyl) (4-piperidyl)methanone-(Z)-O-ethyloxime and its acid salts, and similar compounds, in high stereochemical purity.

Abstract: Compositions and methods for depositing gold alloys are disclosed. The compositions include certain dithiocarboxylic acids, salts and esters thereof and mercapto group containing compounds which provide bright gold alloy deposits with uniform color.

Abstract: A system and method for receiving and tracking a plurality of transactions and distributing the transactions to at least two replication queues over a network. The system and method comprise a global queue for storing a number of the received transactions in a first predetermined order. The system and method also comprise a sequencer coupled to the global queue for creating a copy of each of the transactions for each of said at least two replication queues and for distributing in a second predetermined order each said copy to each of said at least two replication queues respectively, said copy containing one or more of the received transactions.

Abstract: A data storage medium includes a first storage unit and a second storage unit. The first storage unit is used to store a target electronic device ID, the second storage unit stores software installation data. The software installation data includes a copyright protection module, a software installation program, and a software data. When the software installation data is invoked to install the software data, the copyright protection module is invoked and automatically runs. The copyright protection module accesses the first storage unit and reads the target electronic device ID. The software data can be installed in the target electronic device only if the first storage unit contained the target electronic device ID or the first storage unit is writable and the target electronic device ID is stored in the first storage unit successfully.

Abstract: The present invention provides a method for depositing a dielectric stack comprising forming a dielectric layer atop a substrate, the dielectric layer comprising at least oxygen and silicon atoms; forming a layer of metal atoms atop the dielectric layer within a non-oxidizing atmosphere, wherein the layer of metal atoms has a thickness of less than about 15 ?; forming an oxygen diffusion barrier atop the layer of metal atoms, wherein the non-oxidizing atmosphere is maintained; forming a gate conductor atop the oxygen diffusion barrier; and annealing the layer of metal atoms and the dielectric layer, wherein the layer of metal atoms reacts with the dielectric layer to provide a continuous metal oxide layer having a dielectric constant ranging from about 25 to about 30 and a thickness less than about 15 ?.

Abstract: Creatine compounds for the treatment of dermatitis are described.

Abstract: An electromagnetic shield is configured for blocking electromagnetic waves in a mobile communication device. The electromagnetic shield includes an organic glass layer and an indium tin oxide layer. The organic glass layer is configured for providing main body of the electromagnetic shield. The indium tin oxide layer is plated on the organic glass layer for blocking the electromagnetic waves.

Abstract: An integrated circuit product includes: 1) a package, 2) a semiconductor die mounted within the package, 3) a first terminal and a second terminal for connecting the integrated circuit product to an external circuit, 4) one or more bond wires for transferring a current received at the first terminal to the second terminal; and 5) a circuit included in the semiconductor die that measures a voltage difference attributable to the resistance of the bond wires to measure the magnitude of the current passing through the first terminal.

Abstract: A touch-based apparatus includes a display screen, a sensitive screen, and a micro processing unit. The sensitive screen and the display screen are coupled to the micro processing unit. The display screen is used for displaying images or icons. The sensitive screen is used for detecting positional coordinate of the touched portion. The micro processing unit is used for calculating an area of the touched portion according to the positional coordinate, and adjusting a display ratio of the images and icons based on the calculated areas.

Abstract: The present invention discloses a method for coordinating zero or more modelings, zero or more implementations and zero or more deployments of a computer system, including but not limited to computer systems involving sensors, actuators, or both and a system providing assistance to designers, implementers, and deployers of computer systems. The method and system including: defining one or more interfaces of one or more components; creating models for the one or more components, each of which is either a composite component model or a atomic component, model, creating the one or more composite components as instances of the composite component models creating the one or more atomic components as instances of the atomic component models creating a domain model by specifying the computational resources; and creating a deployment model by specifying one or more component-model instances and specifying which the component-model instances should be executed on which the computational resources of the domain model.

Abstract: A method for managing access authorization of peripherals of an electronic apparatus is provided. The method includes the step of: providing a data storage for storing a peripheral registry table which stores hardware IDs of the peripherals; reading the hardware ID of the peripheral when the peripheral is connected to the electronic apparatus; determining whether the hardware ID is recorded in the peripheral registry table; activating an access of the peripheral when the hardware ID is recorded in the peripheral registry table; and registering the hardware ID of the peripheral into the peripheral registry table when the hardware ID is not recorded in the peripheral registry table.

Abstract: The present invention relates to methods and compositions for treatment of cardiovascular and peripheral vascular diseases using ex vivo and in vivo gene delivery technologies. One aspect of the present invention relates to a method for treating a vascular disease by introducing a DNA sequence encoding a TM protein or its variant into a segment of a blood vessel ex vivo using a gutless adenovirus vector. Another aspect of the present invention is to provide a gutless adenovirus vector carrying a transgene, such as a gene encoding TM protein or its variant.

Abstract: Potential magnetic resonance imaging (MRI) contrast agents that are functionalized with crown compounds have been synthesized, and show target-specificity to the kidney and liver, along with excellent water solubility, high MR intensity enhancement efficiency, long resident lifetime, low dosage requirement, low cytotoxicity and prolonged excretion rate.

Abstract: A remote-controlled toy helicopter comprises a body; a motor in the helicopter, a battery for powering the motor, and a receiver for communicating signals between the motor and a separate remote controller. A main rotor with blades is driven by a rotor shaft and causing a first lift force developed by the main rotor when the helicopter is airborne. A system permits movement of the helicopter on the ground, and these can be wheels. The helicopter travels on a floor or ground surface when the main rotor develops a second degree of lift force. The helicopter includes a system to effect motion in a horizontal dimension thereby to direct the desired direction. The control includes an actuator for engaging with an assembly depending from the rotor, the inter-engagement of the actuator and assembly effecting a change in the angle of incidence of at least the one blade of the rotor. The system includes a rotor, preferably complemented with a stabilizer rotor.

Abstract: An aqueous tube cleaning apparatus and method includes a cleaning receptacle and a vertical receptacle, which is taller than the cleaning receptacle. A tube, or bundle of tubes, is placed in the cleaning receptacle, extending through an inlet port from the vertical receptacle, and a gate is closed to clamp the tubes in place. The vertical receptacle is then filled with a fluid, and the pressure created by gravity forces the fluid through and around the tubes, cleansing the inner and outer surfaces of the tubes.

Abstract: A ball with a hollow inner core filled approximately 50% or less by volume with a fluid (which can include metallic spheres), a ball shell and struts (six or more) attached to the core and connected to an inner surface of the ball in such a way so as to maintain the core at the center of the ball. A swirling motion of the fluid within the hollow inner core determines the motion of the ball and a direction of travel away from a point of contact at which a force is applied to the ball to cause it to move or change direction. The direction of travel of the ball will be to the right when a counterclockwise spin is applied to the ball at the point of contact, the direction of travel of the ball will be to the left when it a clockwise spin is applied to the ball at the point of contact, and the direction of travel of the ball will be straight when a top spin is applied to ball at the point of contact. The weight ratio of the fluid to the ball without the fluid is approximately 1:1 or greater.