Abstract: The present disclosure relates to certain (2S)—N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

Abstract: Barriers may utilize cores that may be pre-assembled and dropped into a barrier or may be formed within the barriers. The cores may include traditional core materials, biomass materials, graphite polystyrene (GPS) material, or other types of materials. The core may be formed from one or more layers, such as one or more stiffener layers (e.g., stiffener panel, stiffener rods, or the like), one or more matrix layers (e.g., with apertures extending therein), one or more solid layers (e.g., wood, plastic, composite, foam, fiber, or the like), one or more fluid sealed layers (e.g., air, argon, nitrogen, or other like), and/or other types of layers. The barrier edge members, the faces, and/or the core layers described herein may be assembled to each other in traditional ways, such as welding, and/or may be assembled to each other in a way that reduces the amount of welding and/or use of steel.

Abstract: A method, computer program product, and computing system for receiving a plurality of requests to perform an operation of a first operation type on a storage object. A shared write lock associated with the first operation type is provided to each thread requesting to perform an operation of the first operation type. Concurrent requests to perform operations of the first operation type on the storage object are processed by each requesting thread based upon, at least in part, the shared write lock associated with the first operation type provided to each requesting thread.

Abstract: Provided are embodiments for a wireless gateway device for a heating, ventilation, and air conditioning (HVAC) system for providing sensor information and sensor communication over relay-controlled power line. The wireless gate device includes an input/output (I/O) interface, a communication unit, and a controller. The controller is communicably coupled with the I/O interface and the communication unit. The controller is configured to receive operational data from at least one of one or more sensors and a thermostat of the HVAC system over the power line. The controller is also configured to control one or more components of the HVAC system based on the operational data associated with the HVAC system. The controller can also transmit the operational data to a remote server.

Abstract: Provided are compounds useful for treating of cancer and methods for treating of cancer, comprising administering to a subject in need thereof a compound described therein.

Abstract: A wireless communication system receives a registration cause for a User Equipment (UE) from a user data system. The wireless communication system generates a network message that indicates the registration cause for the UE. The wireless communication system transfers the network message that indicates the registration cause to the UE. The wireless communication system receives a registration request from the UE that indicates the registration cause. In response, the wireless communication system registers the UE to use the wireless communication system based on the registration cause.

Abstract: Systems and methods are directed to building annotated models based on eyes-off data. Specifically, a synthetic data generation model is trained and used to further train a target model. The synthetic data generation model is trained within an eyes-off environment using an anonymity technique on confidential data. The synthetic data generation model is then used to create synthetic data that closely represents the confidential data but without any specific details that can be linked back to the confidential data. The synthetic data is then annotated and used to train the target model within an eyes-on environment. Subsequently, the target model is deployed back within the eyes-off environment to classify the confidential data.

Abstract: A calibration method for determining angles between an image acquisition module reference frame and an accelerometer reference frame of a portable electronic device.

Abstract: In a method for connecting a plurality of devices for a wireless mesh communication network, a first device becomes a leader device for the wireless mesh communication network, where the leader device manages the plurality of devices and the wireless mesh communication network, a second device becomes a first node device by an onboarding process, where the second device becomes the first node device within the wireless mesh communication network of the leader device, and a third device becomes a second node device by the onboarding process, where the third device becomes the second node device within the wireless mesh communication network. A secure digital key is created at the first device for the second and the third devices to wirelessly communicate with the second device and the third devices securely. The first device wirelessly communicates with the second device, either directly or through the third device.

Abstract: A low level contact resistance (LLCR) testing apparatus comprises a test board, an interface board, and a patch board. The test board comprises a processor socket. The interface board connects to both the test board and the patch board. The patch board connects to a contact resistance tester. An LLCR system comprising the LLCR testing apparatus and a contact resistance tester can be portable. The test board can accommodate thermal management solutions of varying sizes and types. Different test board designs can accommodate different socket-processor configurations and the different test boards can be easily accommodated by an LLCR testing apparatus due to its modular design.

Abstract: An enclosure used to mount electrical equipment. The enclosure includes a wall mount section, a center section pivotally attached to the wall mount section along one side, and a latch mechanism securing the opposite side of the center section to the wall mount section. The latch mechanism is accessible only from the front of the enclosure. The latch mechanism has a front latch support, a rear latch support, a cam latch, and an actuation rod. The actuation rod extends through the front latch support and the rear latch support and is secured to the cam latch. The latch mechanism secures the wall mount section to the center section.

Abstract: A powder admixture useful for making a sintered engine part such as a valve seat insert includes a first iron-base powder and second iron-base powder wherein the first iron-base powder has a higher hardness than the second iron-base powder, the first iron-base powder including, in weight percent, 1-2% C, 10-25% Cr, 5-20% Mo, 15-25% Co, and 30-60% Fe, and the second iron-base powder including a vanadium-free tool steel powder such as a vanadium-free tool steel comprising, in weight %, 1-1.5% C, 3-15% Cr, 5-7% Mo, 3-6% W, and 60-85% Fe, the second iron-base powder further comprising vanadium carbide particles in an amount sufficient to reduce adhesive wear. The powder admixture can be sintered to form a sintered engine part optionally infiltrated with copper.

Abstract: A system and method for providing secure access to an organization's internal resources by an application running on an external network. An agent accepts queries from the application which are passed to a relay with a dynamic filter. The relay establishes a secure connection with a connector through the organization's firewall and passes requests from the application to an authentication service running on the internal network to confirm that a user of the application is authorized and issue an authentication ticket which is returned to the application. The application then sends a request to access a specific internal resource based on the authentication ticket, which is passed to a ticket granting service running on the internal network, to verify that said user is authorized to access the specific internal resource, and, if so, issue a service ticket to grant access the application for that resource.

Abstract: A trellis including a first frame to be removeably connected to one or more support posts, the first frame configured to have first plurality of support rods removeably connected thereto in a first orientation and a second plurality of support rods removeably connected thereto in a second orientation. The trellis may include a second frame to be removeably connected to the one or more support posts, the second frame configured to have a third plurality of support rods removeably connected thereto in a third orientation and a fourth plurality of support rods removeably connected thereto in a fourth orientation.

Abstract: A draw-in bar for holding a cover of a vehicle seat on at least one latching receiving element, the draw-in bar having a profile body. The profile body has at least one first profile section with a basic cross section that is constant along a direction of longitudinal extent of the profile body and at least one second profile section with a safety cross section. The safety cross section projects beyond the basic cross section of the profile body in at least one transverse direction in the second profile section. A cover fastening system for a vehicle seat may have the latching receiving element and the draw-in bar where the draw-in bar is connectable to the latching receiving element by a latching connection.

Abstract: The present invention relates to compounds with the ability to stimulate/induce ubiquitination of a target protein/target proteins. The compounds of the present invention may stimulate/induce ubiquitination of a target protein/target proteins; i.e. via degradation of a target protein/target proteins by the cullin-RING ubiquitin ligase (CRL). Such target protein/target proteins may be proteins involved in diseases, like cancer, metabolic disorder, infectious disease and/or neurological disorder. The invention also relates to the compounds and composition for use as medicaments as well as pharmaceutical compositions comprising these compounds. Particularly, the compounds of the present invention may degrade proteins associated with cancer, metabolic disorder, infectious disease and/or neurological disorder.

Abstract: A method of controlling a wind turbine having a tower and a rotor at which plural rotor blades are mounted includes: determining, in particular in real time, a damping characteristic of at least one vibration mode related to the wind turbine; and controlling the wind turbine based on damping characteristic.

Abstract: A lanyard to hold a controller for a headset is provided. The lanyard includes a strap anchored on a top portion of a lid for a battery case of the controller, and a clip anchored to an opening pin in a bottom portion of the lid for the battery case of the controller. The strap includes a stretchable fabric and multiple sticky pads on an outer face that adhere to the stretchable fabric when the strap is looped around the clip. A headset using a controller that includes a lanyard as above, and the controller, are also provided.

Abstract: Various embodiments of a hermetic assembly and a method of forming such assembly are disclosed. The hermetic assembly includes a dielectric substrate having a first major surface and a second major surface, a patterned layer connected to the first major surface of the dielectric substrate by a laser bond, and a ferrule having a body and a flange extending from the body. The flange is welded to a welding portion of the patterned layer that is disposed between the flange and the first major surface of the dielectric substrate such that the ferrule is hermetically sealed to the dielectric substrate.

Abstract: The invention relates to electronic indexing, and more particularly, to the indexing, in a cloud, data held in a cloud. Systems and methods of the invention index data by accessing the data in place in the cloud and breaking a job into work items and sending the work items to multiple cloud processes that can each determine whether to index data associated with the work item or to create a new work item and have a different cloud process index the data. Each cloud process is proximal to an item that it indexes. This gives the system scale as well as an internal load-balancing.