Patents by Inventor Osamu Asano

Osamu Asano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7189717
    Abstract: The present invention provides a medicament having a gentle but strong defecation-promoting action without causing diarrhea. That is, it provides a defecation-promoting agent comprising a compound having an adenosine A2 receptor antagonism, preferably an adenosine A2b receptor antagonism, or a salt thereof.
    Type: Grant
    Filed: April 26, 2001
    Date of Patent: March 13, 2007
    Assignee: Eisai Co., Ltd.
    Inventors: Masahiro Yasuda, Hitoshi Harada, Shuhei Miyazawa, Seiichi Kobayashi, Kokichi Harada, Takayuki Hida, Hisashi Shibata, Nobuyuki Yasuda, Osamu Asano, Yoshihiko Kotake
  • Publication number: 20070054876
    Abstract: The present invention provides a medicament having a gentle but strong defecation-promoting action without causing diarrhea. That is, it provides a defecation-promoting agent comprising a compound having an adenosine A2 receptor antagonism, preferably an adenosine A2b receptor antagonism, or a salt thereof.
    Type: Application
    Filed: November 8, 2006
    Publication date: March 8, 2007
    Inventors: Masahiro Yasuda, Hitoshi Harada, Shuhei Miyazawa, Seiichi Kobayashi, Kokichi Harada, Takayuki Hida, Hisashi Shibata, Nobuyuki Yasuda, Osamu Asano, Yoshihiko Kotake
  • Patent number: 7160892
    Abstract: The invention provides novel pyrimidone compounds exhibiting excellent antagonism against adenosine receptors (A1, A2A, and A2B receptors), particularly, compounds represented by the general formula (1), salts thereof, or solvates of both: (1) wherein R1 and R2 are each independently hydrogen, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-8 cycloalkyl, C3-8 cycloalkenyl, a 5- to 14-membered nonaromatic heterocyclic group, a C6-14 aromatic hydrocarbon group, a 5- to 14-membered aromatic heterocyclic group, C1-6 acyl, or C1-6 alkylsulfonyl; R3 is hydrogen, C1-6 alkyl, C2-6 alkenyl, or C2-6 alkynyl; R4 is a C6-14 aromatic hydrocarbon group; a 5- to 14-membered aromatic heterocyclic group, or a 5- to 14-membered nonaromatic heterocyclic group having at least one unsaturated bond; and R5 is a C6-14 aromatic hydrocarbon group or a 5- to 14-membered aromatic heterocyclic group (with the proviso that every group except hydrogen may be substituted).
    Type: Grant
    Filed: October 22, 2002
    Date of Patent: January 9, 2007
    Assignee: Eisai Co., Ltd.
    Inventors: Hitoshi Harada, Osamu Asano, Masato Ueda, Shuhei Miyazawa, Yoshihiko Kotake, Yasuhiro Kabasawa, Masahiro Yasuda, Nobuyuki Yasuda
  • Publication number: 20060270674
    Abstract: The present invention provides a medicament having a gentle but strong defecation-promoting action without causing diarrhea. That is, it provides a defecation-promoting agent comprising a compound having an adenosine A2receptor antagonism, preferably an adenosine A2b receptor antagonism, or a salt thereof.
    Type: Application
    Filed: August 9, 2006
    Publication date: November 30, 2006
    Inventors: Masahiro Yasuda, Hitoshi Harada, Shuhei Miyazawa, Seiichi Kobayashi, Kokichi Harada, Takayuki Hida, Hisashi Shibata, Nobuyuki Yasuda, Osamu Asano, Yoshihiko Kotake
  • Publication number: 20060083873
    Abstract: A heat insulating and shielding glass panel that is capable of maintaining heat shielding performance even if heat treatment is carried out during manufacture. The heat insulating and shielding glass panel 1 is comprised of a pair of glass plates 11 and 12 that are hermetically joined together at their outer peripheral edges via a sealing frame 13 that fluidizes at low temperature, such that respective one surfaces of the glass plates 11, 12 face each other and a hollow layer 14 is formed between the glass plates; and pillars 15 that are substantially cylindrical spacers that are inserted into the hollow layer 14 as atmospheric pressure supporting members and determine the gap between the glass plates 11 and 12. A low-emission transparent multilayer 17 having an emittance of not more than 0.1 is coated by sputtering on each of surfaces 11a and 12a of the respective glass plates 11 and 12 facing the hollow layer 14 so as to realize high heat insulation performance.
    Type: Application
    Filed: November 28, 2005
    Publication date: April 20, 2006
    Applicant: Nippon Sheet Glass Company, Limited
    Inventors: Osamu Asano, Terufusa Kunisada, Tetsuo Minaai
  • Publication number: 20050183375
    Abstract: A plate-shaped article carrier that enables vibration/movement of plate-shaped articles during carriage to be reliably prevented. A glass plate carrier 100 includes a frame 20 having a floor plate frame 21 and supporting pillars 22, partitioning beams 40 erected on the floor plate frame 21 such that glass plates 10 can be stored therebetween, a pair of end panel frames 50 erected between the supporting pillars 22, and upper beams 60 that restrain upper edges of the stored glass plates 10. Each of the end panels 50 includes of eight pipes 51 arranged vertically, sliding guides 52, and stoppers 53 fixed to the sliding guides 52. Each of the upper beams 60 is laid horizontally over the upper edge of the corresponding glass plate 10, and is fixed to a pair of the pipes 51 that face one another. During carriage of the glass plates 10, the upper beams 60 are placed on the upper edges of the glass plates 10, and the upper beams 60 are supported by the frame 20 via the end panels 50.
    Type: Application
    Filed: December 20, 2004
    Publication date: August 25, 2005
    Applicant: NIPPON SHEET GLASS COMPANY, LIMITED
    Inventors: Takashi Yamamoto, Katsumi Haishima, Osamu Asano, Takaya Motoki, Takashi Fujiya
  • Patent number: 6916837
    Abstract: Amidino derivatives represented by the following general formula (I): {where X is a group represented by R1SO2NR2— (wherein R1 represents optionally substituted C6-14 aryl, etc. and R2 represents hydrogen atom, etc.), etc., Ar1 represents 2,6-naphthylene, etc., R3 represents hydrogen atom, etc. and Y represents carboxyphenyl, etc.} and their pharmacologically acceptable salts or solvates.
    Type: Grant
    Filed: November 14, 2002
    Date of Patent: July 12, 2005
    Assignee: Eisai Co., Ltd.
    Inventors: Takashi Satoh, Yasushi Okamoto, Osamu Asano, Nobuhisa Watanabe, Tadashi Nagakura, Takao Saeki, Atsushi Inoue, Masahiro Sakurai
  • Patent number: 6841549
    Abstract: The present invention provides a preventive or therapeutic agent for diabetes mellitus and diabetic complications, which is a new type based on an adenosine A2 receptor antagonist action. That is, it provides a novel condensed imidazole compound which has an adenosine A2 receptor antagonist action, is effective for preventing or treating diabetes mellitus and diabetic complications, and is represented by the formula (I); (wherein R1 represents e.g. an amino group which may be substituted with an alkyl group; R2 represents e.g. hydrogen atom, an alkyl group, a cycloalkyl group or an alkyl group, alkenyl group or alkynyl group which may be substituted with hydrox etc.; R3 represents e.g. an optionally substituted alkyl group, alkenyl group, alkynyl group, aryl group, heteroaryl group, pyridinone group, pyrimidinone group or piperadinone group; Ar represents e.g.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: January 11, 2005
    Assignee: Eisai Co., Ltd.
    Inventors: Osamu Asano, Hitoshi Harada, Seiji Yoshikawa, Nobuhisa Watanabe, Takashi Inoue, Tatsuo Horizoe, Nobuyuki Yasuda, Kaya Ohashi, Hiroe Minami, Junsaku Nagaoka, Manabu Murakami, Seiichi Kobayashi, Isao Tanaka, Tsutomu Kawata, Naoyuki Shimomura, Hiroshi Akamatsu, Naoki Ozeki, Toshikazu Shimizu, Kenji Hayashi, Toyokazu Haga, Shigeto Negi, Toshihiko Naito
  • Publication number: 20050004149
    Abstract: The present invention provides a novel pyrimidine compound having an excellent adenosine receptor (A1, A2A, A2B receptor) antagonistic action. More specifically, it provides a compound represented by the following formula, a salt thereof or a solvate of them.
    Type: Application
    Filed: October 22, 2002
    Publication date: January 6, 2005
    Inventors: Hitoshi Harada, Osamu Asano, Masato Ueda, Shuhei Miyazawa, Yoshihiko Kotake, Yasuhiro Kabasawa, Masahiro Yasuda, Nobuyuki Yasuda, Daisuke Iida, Junichi Nagakawa, Kazuo Hirota, Makoto Nakagawa
  • Publication number: 20040259865
    Abstract: The present invention provides a medicament having a gentle but strong defecation-promoting action without causing diarrhea. That is, it provides a defecation-promoting agent comprising a compound having an adenosine A2 receptor antagonism, preferably an adenosine A2b receptor antagonism, or a salt thereof.
    Type: Application
    Filed: April 14, 2004
    Publication date: December 23, 2004
    Inventors: Hitoshi Harada, Osamu Asano, Masato Ueda, Shuhei Miyazawa, Yoshihiko Kotake, Yasuhiro Kabasawa, Masahiro Yasuda, Nobuyuki Yasuda
  • Patent number: 6790494
    Abstract: A heat insulating/heat shielding glass panel is produced by forming a functional film on a sheet of plate glass, which film is high in solar radiation reflectance, small in solar radiation absorptivity, and has emissivity of 0.20 or less, superposing another sheet of plate glass on the side of the functional film, and adhesively sealing the two sheets of plate glass, under the condition that a gap layer is provided between the two sheets of plate glass. Accordingly, there is obtained a glass panel which has a sufficient heat insulating performance and a sufficient heat shielding performance, and in which no warping is generated even when suffering the solar radiation.
    Type: Grant
    Filed: March 21, 2003
    Date of Patent: September 14, 2004
    Assignee: Nippon Sheet Glass Co., Ltd.
    Inventors: Osamu Asano, Terufusa Kunisada, Tetsuo Minaai
  • Patent number: 6750232
    Abstract: A class of substituted compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by formula (II), wherein R1 is selected from hydrido, halo, alkoxy, aryl, alkylthio, alkylamino, aralkoxy, azido and alkenyloxy; wherein R2 is selected from hydrido, cyano, hydroxyalkyl, haloalkyl, aminoalkyl, alkylaminoalkyl, alkylcarbonyloxyalkyl, aminocarbonyl and alkylcarbonylaminoalkyl; and wherein R5 and R6 are one more radicals independently selected from halo, alkylsulfonyl, aminosulfonyl, alkoxy and alkylthio; provided one of R5 and R6 is substituted with alkysulfonyl, aminosulfonyl, or haloalkylsulfonyl; or a pharmaceutically-acceptable salt thereof.
    Type: Grant
    Filed: January 23, 2003
    Date of Patent: June 15, 2004
    Assignee: Eisai Co., Ltd.
    Inventors: Hitoshi Harada, Osamu Asano, Shuhei Miyazawa, Masato Ueda, Masahiro Yasuda, Nobuyuki Yasuda
  • Publication number: 20040098482
    Abstract: The invention provides a hub unit that prevents the spread of viruses in a communications network. A hub unit connected to a plurality of communication devices, which controls transmission and reception of data between the devices, comprises: a first memory unit storing virus pattern information; a second memory unit temporarily storing data received from any one of the communication devices; a virus detecting unit that determines whether the data temporarily stored in the second memory unit is infected with a virus or not by comparing the virus patterns stored in the first memory unit with the data temporarily stored in the second memory unit; a virus spreading preventing unit that disables transmission of the data outside the hub unit when the detecting unit determines that the data is infected with a virus; and a third memory unit storing transmission MAC addresses of the plurality of communication devices connected to the hub.
    Type: Application
    Filed: November 14, 2003
    Publication date: May 20, 2004
    Applicant: FUJITSU LIMITED
    Inventor: Osamu Asano
  • Patent number: 6734128
    Abstract: The invention provides a method for producing a polycrystalline transparent sintered alumina body suitable for use in a ceramic envelope for a high intensity discharge lamp, with optimized kinds and amounts of sintering aids. First, adding and mixing, to alumina of a purity of 99.9% or higher, MgO within a range from 0.002 to 0.010 wt. % and La2O3 within a range from 0.005 to 0.020 wt. %, in such a manner that a sum of MgO and La2O3 is 0.030 wt. % or less and that a ratio thereof satisfies a relation 0.2≦MgO/La2O3≦0.5. Next, firing a mixture at 900 to 1200° C. and cast molding the fired alumina. Then, after a chelating treatment, sintering the molded alumina for at least 1 hour at 1650 to 1900° C. in a reducing atmosphere under a normal pressure.
    Type: Grant
    Filed: February 27, 2003
    Date of Patent: May 11, 2004
    Assignee: NGK Insulators, Ltd.
    Inventor: Osamu Asano
  • Publication number: 20040028845
    Abstract: A heat insulating/heat shielding glass panel is produced by forming a functional film on a sheet of plate glass, which film is high in solar radiation reflectance, small in solar radiation absorptivity, and has emissivity of 0.20 or less, superposing another sheet of plate glass on the side of the functional film, and adhesively sealing the two sheets of plate glass, under the condition that a gap layer is provided between the two sheets of plate glass. Accordingly, there is obtained a glass panel which has a sufficient heat insulating performance and a sufficient heat shielding performance, and in which no warping is generated even when suffering the solar radiation.
    Type: Application
    Filed: March 21, 2003
    Publication date: February 12, 2004
    Inventors: Osamu Asano, Terufusa Kunisada, Tetsuo Minaai
  • Publication number: 20040006082
    Abstract: The present invention provides 2-aminopyridine compound having an excellent adenosine receptor (A1, A2a, A2b receptors) antagonism, which is represented by the following formula: 1
    Type: Application
    Filed: January 23, 2003
    Publication date: January 8, 2004
    Inventors: Hitoshi Harada, Osamu Asano, Shuhei Miyazawa, Masato Ueda, Masahiro Yasuda, Nobuyuki Yasuda
  • Publication number: 20030181766
    Abstract: Amidino derivatives represented by the following general formula (I): 1
    Type: Application
    Filed: November 14, 2002
    Publication date: September 25, 2003
    Inventors: Takashi Satoh, Yasushi Okamoto, Osamu Asano, Nobuhisa Watanabe, Tadashi Nagakura, Takao Saeki, Atsushi Inoue, Masahiro Sakurai
  • Publication number: 20030176272
    Abstract: The invention provides a method for producing a polycrystalline transparent sintered alumina body suitable for use in a ceramic envelope for a high intensity discharge lamp, with optimized kinds and amounts of sintering aids. First, adding and mixing, to alumina of a purity of 99.9% or higher, MgO within a range from 0.002 to 0.010 wt. % and La2O3 within a range from 0.005 to 0.020 wt. %, in such a manner that a sum of MgO and La2O3 is 0.030 wt. % or less and that a ratio thereof satisfies a relation 0.2≦MgO/La2O3≦0.5. Next, firing a mixture at 900 to 1200° C. and cast molding the fired alumina. Then, after a chelating treatment, sintering the molded alumina for at least 1 hour at 1650 to 1900° C. in a reducing atmosphere under a normal pressure.
    Type: Application
    Filed: February 27, 2003
    Publication date: September 18, 2003
    Applicant: NGK INSULATORS, LTD.
    Inventor: Osamu Asano
  • Publication number: 20030171383
    Abstract: The present invention provides a medicament having a gentle but strong defecation-promoting action without causing diarrhea. That is, it provides a defecation-promoting agent comprising a compound having an adenosine A2 receptor antagonism, preferably an adenosine A2b receptor antagonism, or a salt thereof.
    Type: Application
    Filed: October 9, 2002
    Publication date: September 11, 2003
    Inventors: Masahiro Yasuda, Hitoshi Harada, Shuhei Miyazawa, Seiichi Kobayashi, Kokichi Harada, Takayuki Hida, Hisashi Shibata, Nobuyuki Yasuda, Osamu Asano, Yoshihiko Kotake
  • Patent number: RE39112
    Abstract: The present invention provides a preventive or therapeutic agent of a new type for diabetes mellitus and diabetic complications on the basis of an adenosine A2 receptor antagonist action. A purine compound represented by the formula (I), its pharmacologically acceptable salt or hydrates thereof has an adenosine A2 receptor antagonistic action and is useful for prevention or therapy of diabetes mellitus and diabetic complications. In addition, adenosine A2 receptor antagonists having different structures from those of the compounds described above, for example KW6002, are also effective for prevention or therapy of diabetes mellitus and diabetic complications. In the formula, W is —CH2CH2—, or —CH?CH— or —C?C—; R1 is: (in the formula, X is hydrogen atom, hydroxyl group, a lower alkyl group, a lower alkoxy group, etc.; and R5 and R6 are the same as or different from each other and each represents hydrogen atom, a lower alkyl group, a cycloalkyl group, etc.) and the like; R2 is an amino group, etc.
    Type: Grant
    Filed: December 24, 1998
    Date of Patent: May 30, 2006
    Assignee: Eisai Co., Ltd.
    Inventors: Osamu Asano, Hitoshi Harada, Yorihisa Hoshino, Seiji Yoshikawa, Takashi Inoue, Tatsuo Horizoe, Nobuyuki Yasuda, Kaya Ohashi, Junsaku Nagaoka, Manabu Murakami, Seiichi Kobayashi