Abstract: An information processing device that determines a route by which a circuit of a plurality of points is made includes an acquisition unit that acquires point information regarding the points, a determination unit that determines a circuit route that satisfies a first condition for the points based on the point information acquired by the acquisition unit and traffic information, and a transmission unit that transmits the circuit route determined by the determination unit to the outside.

Abstract: A vehicle seat attachable to a vehicle body, the vehicle seat including: a seat back; and a headrest configured to support a head of a seated occupant, the headrest including: a base portion fixed to the seat back; a slide portion slidable in a left-right direction in a state where the head is supported to the base portion; and an electric mechanism configured to slide the slide portion in the left-right direction, and in which the slide portion is configured to be moved by the electric mechanism in a moving direction in which the head moves in the left-right direction due to acceleration in the left-right direction applied when a vehicle moves, the electric mechanism being operated by a control device disposed in the vehicle body in response to a signal from a sensor disposed in the vehicle body, the sensor being configured to detect the moving direction.

Abstract: A vehicle seat attachable to a vehicle body, the vehicle seat including: a seat back; and a headrest configured to support a head of a seated occupant, the headrest including: a base portion fixed to the seat back; a slide portion slidable in a left-right direction in a state where the head is supported to the base portion; and an electric mechanism configured to slide the slide portion in the left-right direction, and in which the slide portion is configured to be moved by the electric mechanism in a moving direction in which the head moves in the left-right direction due to acceleration in the left-right direction applied when a vehicle moves, the electric mechanism being operated by a control device disposed in the vehicle body in response to a signal from a sensor disposed in the vehicle body, the sensor being configured to detect the moving direction.

Abstract: [Problem] To provide a compound which is useful as an agent for preventing and/or treating kidney diseases. [Means for Solution] The present inventors have studied compounds having a trypsin inhibitory activity, and have confirmed that a guanidinobenzoic acid ester compound has a trypsin inhibitory activity, thereby completing the present invention. The guanidinobenzoic acid ester compound of the present invention can be used as an agent for preventing and/or treating kidney diseases (for example, chronic kidney disease, acute glomerulonephritis, acute kidney injury, and the like) as an agent which will substitute low-protein diet therapy, and/or as an agent for preventing and/or treating trypsin-related diseases (for example, chronic pancreatitis, gastroesophageal reflux disease, hepatic encephalopathy, influenza, and the like).

Abstract: A method of manufacturing a polarizing plate according to an embodiment of the present invention includes: stretching and dyeing a laminate including a resin substrate having a long shape and a polyvinyl alcohol-based resin layer formed on one side of the resin substrate, to thereby produce a polarizing film on the resin substrate; laminating an optically functional film on a side of the polarizing film of the laminate, to thereby produce an optically functional film laminate; and cutting widthwise direction end portions of the optically functional film laminate. The cut portions include the resin substrate, the polarizing film, and the optically functional film.

Abstract: Provided is a polarizing film that is excellent in external appearance and can contribute to improving the display characteristics of an image display apparatus. A polarizing film of the present invention includes a polyvinyl alcohol-based resin film containing iodine. At least one surface side of the polyvinyl alcohol-based resin film includes a low-iodine layer.

Abstract: A vehicle seat includes a supporting member that supports a load of a seated person, a cushion frame, a rear pipe that is rotatably attached to the cushion frame, a lifter link that is fixed to the rear pipe, and a bracket that is rotatably attached to the rear pipe. An inclination of the cushion frame changes when the cushion frame is moved up and down by tilting the lifter link. The supporting member is connected to the rear pipe via the bracket.

Abstract: There is provided a vehicle seat including a seat cushion configured to support a weight of a sitting passenger from below, and a seat back configured to support an upper body of the sitting passenger from a back side thereof. The seat back includes a seat back fixing part including a back frame which configures a frame of the seat back, and a seat back moving part configured to support the upper body of the passenger at a passenger sitting surface side of the seat back fixing part. The seat back moving part is supported to the seat back fixing part so as to be rotatable about an upper part thereof in a left-right direction which corresponds to lateral sides of the sitting passenger.

Abstract: [Problem]To provide a compound which is useful as an agent for preventing and/or treating kidney diseases. [Means for Solution]The present inventors have studied compounds having a trypsin inhibitory activity, and have confirmed that a guanidinobenzoic acid ester compound has a trypsin inhibitory activity, thereby completing the present invention. The guanidinobenzoic acid ester compound of the present invention can be used as an agent for preventing and/or treating kidney diseases (for example, chronic kidney disease, acute glomerulonephritis, acute kidney injury, and the like) as an agent which will substitute low-protein diet therapy, and/or as an agent for preventing and/or treating trypsin-related diseases (for example, chronic pancreatitis, gastroesophageal reflux disease, hepatic encephalopathy, influenza, and the like).

Abstract: A vehicle seat includes a supporting member that supports a load of a seated person, a cushion frame, a rear pipe that is rotatably attached to the cushion frame, a lifter link that is fixed to the rear pipe, and a bracket that is rotatably attached to the rear pipe. An inclination of the cushion frame changes when the cushion frame is moved up and down by tilting the lifter link. The supporting member is connected to the rear pipe via the bracket.

Abstract: A method of manufacturing a polarizing plate according to an embodiment of the present invention includes: stretching and dyeing a laminate having a resin substrate and a polyvinyl alcohol-based resin layer formed on at least one side of the resin substrate to produce a polarizing film on the resin substrate; laminating an optically functional film on the laminate on a polarizing film side to produce an optically functional film laminate; and peeling the resin substrate from the optically functional film laminate. The peeling is performed so that an angle ? formed between a surface of the optically functional film laminate immediately before the peeling and a peeling direction of the resin substrate is smaller than an angle ? formed between the surface of the optically functional film laminate immediately before the peeling and a peeling direction of the polarizing film.

Abstract: Provided is a polarizing film that is excellent in external appearance and can contribute to improving the display characteristics of an image display apparatus. A polarizing film of the present invention includes a polyvinyl alcohol-based resin film containing iodine. At least one surface side of the polyvinyl alcohol-based resin film includes a low-iodine layer.

Abstract: A method of manufacturing a polarizing plate according to an embodiment of the present invention includes: stretching and dyeing a laminate having a resin substrate and a polyvinyl alcohol-based resin layer formed on at least one side of the resin substrate to produce a polarizing film on the resin substrate; laminating an optically functional film on the laminate on a polarizing film side to produce an optically functional film laminate; and peeling the resin substrate from the optically functional film laminate. The peeling is performed so that an angle ? formed between a surface of the optically functional film laminate immediately before the peeling and a peeling direction of the resin substrate is smaller than an angle ? formed between the surface of the optically functional film laminate immediately before the peeling and a peeling direction of the polarizing film.

Abstract: There is provided a vehicle seat including a seat cushion configured to support a weight of a sitting passenger from below, and a seat back configured to support an upper body of the sitting passenger from a back side thereof. The seat back includes a seat back fixing part including a back frame which configures a frame of the seat back, and a seat back moving part configured to support the upper body of the passenger at a passenger sitting surface side of the seat back fixing part. The seat back moving part is supported to the seat back fixing part so as to be rotatable about an upper part thereof in a left-right direction which corresponds to lateral sides of the sitting passenger.

Abstract: To provide an excellent agent for preventing or treating dementia and schizophrenia based on serotonin 5-HT5A receptor regulating action, it was found that a tetrahydroisoquinoline derivative characterized by a structure in which an acylguanidino group binds to a N atom of a tetrahydroisoquinoline ring or the like, and a cyclic group binds to an unsaturated ring has a potent 5-HT5A receptor regulating action and an excellent pharmacological action based on the regulating action and also discovered that the tetrahydroisoquinoline derivative is useful as an agent for treating or preventing dementia, schizophrenia, and the like, whereby the present invention has been completed.

Abstract: A method of manufacturing a polarizing plate according to an embodiment of the present invention includes: stretching and dyeing a laminate having a resin substrate and a polyvinyl alcohol-based resin layer formed on at least one side of the resin substrate to produce a polarizing film on the resin substrate; laminating an optically functional film on the laminate on a polarizing film side to produce an optically functional film laminate; and peeling the resin substrate from the optically functional film laminate. The peeling is performed so that an angle ? formed between a surface of the optically functional film laminate immediately before the peeling and a peeling direction of the resin substrate is smaller than an angle ? formed between the surface of the optically functional film laminate immediately before the peeling and a peeling direction of the polarizing film.

Abstract: A method of manufacturing a polarizing plate according to an embodiment of the present invention includes: stretching and dyeing a laminate including a resin substrate having a long shape and a polyvinyl alcohol-based resin layer formed on one side of the resin substrate, to thereby produce a polarizing film on the resin substrate; laminating an optically functional film on a side of the polarizing film of the laminate, to thereby produce an optically functional film laminate; and cutting widthwise direction end portions of the optically functional film laminate. The cut portions include the resin substrate, the polarizing film, and the optically functional film.

Abstract: The present invention provides mesothelin peptide fragments corresponding to the CA125 binding site of mesothelin. The peptide fragments find use in disrupting the binding interaction between mesothelin and CA 125, for example, in the treatment and prevention of cancers that require the interaction of mesothelin and CA125 for growth, progression and/or metastasis.

Abstract: To provide an excellent agent for preventing or treating dementia and schizophrenia based on serotonin 5-HT5A receptor regulating action, it was found that a tetrahydroisoquinoline derivative characterized by a structure in which an acylguanidino group binds to a N atom of a tetrahydroisoquinoline ring or the like, and a cyclic group binds to an unsaturated ring has a potent 5-HT5A receptor regulating action and an excellent pharmacological action based on the regulating action and also discovered that the tetrahydroisoquinoline derivative is useful as an agent for treating or preventing dementia, schizophrenia, and the like, whereby the present invention has been completed.

Abstract: The present invention provides mesothelin peptide fragments corresponding to the CA125 binding site of mesothelin. The peptide fragments find use in disrupting the binding interaction between mesothelin and CA 125, for example, in the treatment and prevention of cancers that require the interaction of mesothelin and CA125 for growth, progression and/or metastasis.