Patents by Inventor Osamu Suzuki
Osamu Suzuki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250035618Abstract: It is an object of the present invention to provide a method for suppressing non-specific reactions using a highly versatile method without affecting specific reactions. The present invention provides a detection method for detecting a target antigen in a sample using a specific antibody that specifically binds to the antigen, the method comprising: a) a step of bringing the sample into contact with a modified antibody; and b) a step of bringing the sample into contact with the specific antibody simultaneously with or after the step a), which is a highly versatile method that can suppress non-specific reactions.Type: ApplicationFiled: December 27, 2022Publication date: January 30, 2025Applicant: SEKISUI MEDICAL CO., LTD.Inventors: Daisuke YAMADA, Ikumi SUZUKI, Kengo FUJIMURA, Tomohide ASAI, Osamu MIYAZAKI
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Publication number: 20240293599Abstract: A bone-regeneration-promoting material containing a composite of octacalcium phosphate and a bioabsorbable polymer and having edge dislocations introduced in the octacalcium phosphate in which the total dislocation density of the octacalcium phosphate is 0.30×1017 m?2 or more.Type: ApplicationFiled: May 14, 2024Publication date: September 5, 2024Inventors: Osamu SUZUKI, Ryo HAMAI, Susumu SAKAI, Kaori TSUCHIYA
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Publication number: 20240293451Abstract: An angiogenesis material, a bone-regeneration-promoting material, a method for producing an angiogenesis material and a method for producing a bone-regeneration-promoting material which particularly improve angiogenesis capacity, angiogenesis capacity and osteogenesis capacity, are particularly effective for bone regeneration and are expected to be applied not only to bone regeneration but also to regeneration of various tissues in which angiogenesis is required are provided. These are an angiogenesis material containing a composite of a metal-octacalcium phosphate-containing material containing octacalcium phosphate and a metal element and a bioabsorbable polymer, a bone-regeneration-promoting material using the same, and production methods thereof.Type: ApplicationFiled: May 9, 2024Publication date: September 5, 2024Inventors: Osamu SUZUKI, Ryo HAMAI, Yukari SHIWAKU, Kaori TSUCHIYA, Shinki KOUYAMA
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Patent number: 12071413Abstract: The present invention relates to a novel azole derivative as an apelin receptor agonist and a method for treating cardiovascular disease, diabetic disease, renal disease, hypertension, and arteriosclerosis, etc., using the same. The present invention provides a compound represented by formula (I) or a pharmacologically acceptable salt thereof wherein X1 represents —N? or —CH?, X2 represents —CH? or —N?, R1 and R2 each represent a C1 to C6 alkoxy group or the like, R3 represents a heteroaryl group (the heteroaryl group is optionally substituted by a methyl group or the like) or the like, and R4 represents a C1 to C6 alkylthio group or a C2 to C6 alkenyl group (the C1 to C6 alkylthio group and the C2 to C6 alkenyl group are each optionally substituted by one carboxy group or the like) or the like.Type: GrantFiled: October 20, 2021Date of Patent: August 27, 2024Assignee: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTEInventors: Takuya Ikeda, Yoshiyuki Kobayashi, Naoki Miyoshi, Osamu Suzuki, Takahiro Nagayama, Takashi Tsuji, Layton H. Smith, Anthony B. Pinkerton
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Patent number: 11953137Abstract: A rotary joint capable of lubricating a sealing surface of a mechanical seal forming a fluid passage through which a gas flows using a liquid even when the liquid flows through only one fluid passage is disclosed. A rotary joint includes a plurality of mechanical seals provided in an axial direction in an annular space between a case body and a shaft body to form a first intermediate flow passage that connects a first outer flow passage and a first inner flow passage of a first fluid passage through which a liquid flows to each other and form a second intermediate flow passage that connects a second outer flow passage and a second inner flow passage of a second fluid passage through which a gas flows to each other.Type: GrantFiled: December 12, 2018Date of Patent: April 9, 2024Assignee: Nippon Pillar Packing Co., Ltd.Inventors: Yoshinori Kikuyama, Osamu Suzuki, Takashi Nishi
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Patent number: 11879549Abstract: Each of mechanical seal devices 7 of a rotary joint 1 includes a first shaft side seal ring 71 and a second shaft side seal ring 72 attached to a shaft body 5, and a first case side seal ring 73 and a second case side seal ring 74 attached to a case body 2. The first shaft side seal ring 71 and the second shaft side seal ring 72 have contact surfaces 71b and 72b axially facing each other and coming into contact with each other, and grooves 421c and 421d for forming a second communication flow passage 42 connecting a second outer flow passage 32 and a second inner flow passage 62 are formed in both the contact surfaces 71b and 72b.Type: GrantFiled: April 17, 2020Date of Patent: January 23, 2024Assignee: NIPPON PILLAR PACKING CO., LTD.Inventors: Masanao Ishijima, Osamu Suzuki, Yasuyuki Okunishi, Shuhei Matsui
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Publication number: 20230330248Abstract: [Problem] It is desired to develop an antibody-drug conjugate capable of being systemically administered and delivering a STING agonist specifically to a target cells or organ (for example, a tumor lesion), and a therapeutic agent and/or therapeutic method using the antibody-drug conjugate for diseases related to STING agonist activity, for example, diseases (for example, cancers) to which immunostimulation therapy can be applied. [Solution] The present invention provides a novel antibody-CDN derivative conjugate which can be systemically administered and exhibits an antitumor effect against an antigen-expressing tumor.Type: ApplicationFiled: March 5, 2021Publication date: October 19, 2023Applicant: DAIICHI SANKYO COMPANY, LIMITEDInventors: Masayuki ISHIZAKI, Osamu SUZUKI, Mariko KYUTOKU, Hiroshi YUKIURA, Kyoko HARA, Masataka CHIHARA, Takafumi OTSUKA, Teiji WADA
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Patent number: 11781236Abstract: [Problem] An object is to provide novel composite copper foils. [Means to solve the problem] A composite copper foil comprises a copper foil and a layer of metal other than copper, the metal layer being formed on at least a part of a surface of the copper foil, wherein at least a part of the composite copper foil has protrusions on a surface thereof, and each protrusion has a height of 10 nm or more but 1000 nm or less in a cross-section of the composite copper foil.Type: GrantFiled: November 9, 2018Date of Patent: October 10, 2023Assignee: NAMICS CORPORATIONInventors: Makiko Sato, Osamu Suzuki, Naoki Obata, Yoshinobu Kokaji
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Patent number: 11774018Abstract: Each of the mechanical seal devices of a rotary joint includes a first shaft side seal ring attached to a shaft body and a first case slide seal ring attached to one side of the first shaft side seal ring as well as a second case side seal ring attached to a case body and a second shaft side seal ring attached to the second case side seal ring. A first communication flow passage is formed between a first sliding portion of the first seal rings and a second sliding portion of the second seal rings. A second communication flow passage is formed between the first sliding portion of a mechanical seal device disposed on one side in the axial direction and the second sliding portion of a mechanical seal device disposed on the other side in the axial direction in mechanical seal devices adjacent to each other.Type: GrantFiled: September 25, 2019Date of Patent: October 3, 2023Assignee: NIPPON PILLAR PACKING CO., LTD.Inventors: Osamu Suzuki, Yasuyuki Okunishi, Shuhei Matsui, Masanao Ishijima
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Publication number: 20230238208Abstract: A sample cartridge has a sample stand and an inclining mechanism. A sample cartridge holding apparatus has a housing part which is inclined. When the sample cartridge is inserted into the housing part, a contact portion contacts a lever of the inclining mechanism, and the sample stand is inclined by a predetermined angle. With this process, an appropriate inclination angle is realized for the sample stand.Type: ApplicationFiled: January 25, 2023Publication date: July 27, 2023Inventors: Norimasa Sakuta, Tomohisa Fukuda, Osamu Suzuki, Masateru Shibata
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Publication number: 20230203301Abstract: A plasticizer for a vinyl chloride resin with excellent balance of non-transfer properties, fogging resistance, flexibility, heat resistance, and cold resistance is provided. Specifically, a plasticizer for a vinyl chloride resin is a polyester made from a glycol having 2 to 18 carbon atoms, an aliphatic dicarboxylic acid having 4 to 14 carbon atoms, and a monoalcohol having 4 to 18 carbon atoms and/or a monocarboxylic acid having 2 to 21 carbon atoms, as reaction raw materials, in which the polyester has a number average molecular weight in a range of 500 to 6,000 and contains components with a molecular weight of 600 or less in a range of 0.5 to 3.0% by mass in terms of area ratio in gel permeation chromatography measurement.Type: ApplicationFiled: June 10, 2021Publication date: June 29, 2023Applicant: DIC CorporationInventors: Takafumi Noguchi, Hiroki Tokoro, Osamu Suzuki
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Patent number: 11427674Abstract: Provided are: a dispersant for calcium carbonate that is capable of dispersing calcium carbonate well in a thermoplastic resin; a calcium carbonate composition and a thermoplastic resin composition that each contain the dispersant for calcium carbonate; and a molded body produced by using the thermoplastic resin composition. Specifically, provided are a dispersant for calcium carbonate, including a polyester resin containing an aromatic dicarboxylic acid residue, an aliphatic diol residue, and a monoalcohol residue or a monocarboxylic acid residue and having a melting point of 100 to 250° C.; a calcium carbonate composition that contains the dispersant and calcium carbonate; a thermoplastic resin composition that contains the dispersant, calcium carbonate, and a thermoplastic resin; and a molded body that contains the thermoplastic resin composition.Type: GrantFiled: December 5, 2017Date of Patent: August 30, 2022Assignee: DIC CorporationInventors: Yusuke Tajiri, Osamu Suzuki
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Publication number: 20220213180Abstract: [Problem] To provide a therapeutic method specialized for an inflammatory disease such as intractable vasculitis and an infectious disease, which is different from the previous therapeutic methods, in which a target molecule was not determined, by determining the target molecule useful for treating these diseases. [Solution] According to one aspect of the present invention, a prophylactic and/or therapeutic agent for an infectious disease or an inflammatory disease which contains an antibody recognizing apolipoprotein A2 (APOA2) as an active ingredient is provided.Type: ApplicationFiled: March 21, 2022Publication date: July 7, 2022Applicants: A-CLIP Institute, Co., Ltd., National Institutes of Biomedical Innovation, Health and NutritionInventors: Kazuo Suzuki, Yosuke Kameoka, Yoshio Yamakawa, Fukuko Kishi, Osamu Suzuki, Minako Koura, Junichiro Matsuda
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Publication number: 20220205541Abstract: Each of mechanical seal devices 7 of a rotary joint 1 includes a first shaft side seal ring 71 and a second shaft side seal ring 72 attached to a shaft body 5, and a first case side seal ring 73 and a second case side seal ring 74 attached to a case body 2. The first shaft side seal ring 71 and the second shaft side seal ring 72 have contact surfaces 71b and 72b axially facing each other and coming into contact with each other, and grooves 421c and 421d for forming a second communication flow passage 42 connecting a second outer flow passage 32 and a second inner flow passage 62 are formed in both the contact surfaces 71b and 72b.Type: ApplicationFiled: April 17, 2020Publication date: June 30, 2022Applicant: NIPPON PILLAR PACKING CO., LTD.Inventors: Masanao ISHIJIMA, Osamu SUZUKI, Yasuyuki OKUNISHI, Shuhei MATSUI
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Publication number: 20220144784Abstract: The present invention relates to a novel azole derivative as an apelin receptor agonist and a method for treating cardiovascular disease, diabetic disease, renal disease, hypertension, and arteriosclerosis, etc., using the same. The present invention provides a compound represented by formula (I) or a pharmacologically acceptable salt thereof wherein X1 represents —N? or —CH?, X2 represents —CH? or —N?, R1 and R2 each represent a C1 to C6 alkoxy group or the like, R3 represents a heteroaryl group (the heteroaryl group is optionally substituted by a methyl group or the like) or the like, and R4 represents a C1 to C6 alkylthio group or a C2 to C6 alkenyl group (the C1 to C6 alkylthio group and the C2 to C6 alkenyl group are each optionally substituted by one carboxy group or the like) or the like.Type: ApplicationFiled: October 20, 2021Publication date: May 12, 2022Inventors: Takuya IKEDA, Yoshiyuki KOBAYASHI, Naoki MIYOSHI, Osamu SUZUKI, Takahiro NAGAYAMA, Takashi TSUJI, Layton H. SMITH, Anthony B. PINKERTON
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Publication number: 20220120366Abstract: Each of mechanical seal devices of a rotary joint includes a seal ring and a seal ring attached to a shaft body, and a seal ring and a seal ring attached to a case body. A flow passage that partitions an annular space and connects a flow passage and a flow passage is formed between a sliding portion of the seal rings and a sliding portion of the seal rings. A flow passage that partitions the annular space and connects a flow passage and a flow passage is formed between the sliding portion of a mechanical seal device disposed on one side in the axial direction and the sliding portion of a mechanical seal device disposed on the other side in the axial direction in mechanical seal devices adjacent to each other in the axial direction.Type: ApplicationFiled: September 25, 2019Publication date: April 21, 2022Applicant: NIPPON PILLAR PACKING CO., LTD.Inventors: Osamu SUZUKI, Yasuyuki OKUNISHI, Shuhei MATSUI, Masanao ISHIJIMA
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Publication number: 20220122277Abstract: An observation coordinate in the device coordinate system of an observation device is converted into an observation coordinate in a virtual coordinate system, using a conversion formula. Subsequently, the observation coordinate in the virtual coordinate system is converted into an observation coordinate in the device coordinate system of another observation device, using a reverse conversion formula. The virtual coordinate system is a logical coordinate system that does not depend on any device coordinate system.Type: ApplicationFiled: October 13, 2021Publication date: April 21, 2022Inventors: Yuichiro Oohori, Noriaki Mizuno, Osamu Suzuki
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Publication number: 20220054712Abstract: A bone regeneration material according to the present disclosure includes at least a composite of octacalcium phosphate (OCP) particles and gelatin, and is a porous body having a plurality of pores. The particle size of the octacalcium phosphate particles is 1 ?m or more but less than 1 mm, and the molecular weight of the gelatin is in the range of 30 kDa to 70 kDa. Thus, the material is able to resist breaking down during implantation and exhibit high handleability.Type: ApplicationFiled: October 3, 2019Publication date: February 24, 2022Inventors: Osamu SUZUKI, Yoshikatsu SUGAHARA, Satoshi URAI, Yusuke NAKAMURA
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Patent number: 11155525Abstract: The present invention relates to a novel azole derivative as an apelin receptor agonist and a method for treating cardiovascular disease, diabetic disease, renal disease, hypertension, and arteriosclerosis, etc., using the same. The present invention provides a compound represented by formula (I) or a pharmacologically acceptable salt thereof wherein X1 represents —N? or —CH?, X2 represents —CH? or —N?, R1 and R2 each represent a C1 to C6 alkoxy group or the like, R3 represents a heteroaryl group (the heteroaryl group is optionally substituted by a methyl group or the like) or the like, and R4 represents a C1 to C6 alkylthio group or a C2 to C6 alkenyl group (the C1 to C6 alkylthio group and the C2 to C6 alkenyl group are each optionally substituted by one carboxy group or the like) or the like.Type: GrantFiled: April 20, 2020Date of Patent: October 26, 2021Assignee: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTEInventors: Takuya Ikeda, Yoshiyuki Kobayashi, Naoki Miyoshi, Osamu Suzuki, Takahiro Nagayama, Takashi Tsuji, Layton H. Smith, Anthony B. Pinkerton
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Publication number: 20210317937Abstract: Provided is a rotary joint capable of lubricating a sealing surface of a mechanical seal forming a fluid passage through which a gas flows using a liquid even when the liquid flows through only one fluid passage. A rotary joint 1 includes a plurality of mechanical seals 7 provided in an axial direction in an annular space A between a case body 2 and a shaft body 5 to form a first intermediate flow passage 41 that connects a first outer flow passage 31 and a first inner flow passage 61 of a first fluid passage 11 through which a liquid flows to each other and form a second intermediate flow passage 42 that connects a second outer flow passage 32 and a second inner flow passage 62 of a second fluid passage 12 through which a gas flows to each other.Type: ApplicationFiled: December 12, 2018Publication date: October 14, 2021Applicant: NIPPON PILLAR PACKING CO., LTD.Inventors: Yoshinori KIKUYAMA, Osamu SUZUKI, Takashi NISHI