Patents by Inventor Oswald Zimmer

Oswald Zimmer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol
    Patent number: 11739049
    Abstract: The present invention relates to a process for the preparation of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol.
    Type: Grant
    Filed: January 6, 2021
    Date of Patent: August 29, 2023
    Assignee: Grünenthal GmbH
    Inventors: Wolfgang Hell, Oswald Zimmer, Helmut Heinrich Buschmann, Joerg Holenz, Stefan Gladow
  • PROCESS FOR THE PREPARATION OF (1R,2R)-3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL
    Publication number: 20210130282
    Abstract: The present invention relates to a process for the preparation of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol.
    Type: Application
    Filed: January 6, 2021
    Publication date: May 6, 2021
    Applicant: GRÜNENTHAL GMBH
    Inventors: WOLFGANG HELL, OSWALD ZIMMER, HELMUT HEINRICH BUSCHMANN, JOERG HOLENZ, STEFAN GLADOW
  • PROCESS FOR THE PREPARATION OF (1R,2R)-3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL
    Publication number: 20200299225
    Abstract: The present invention relates to a process for the preparation of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol.
    Type: Application
    Filed: June 9, 2020
    Publication date: September 24, 2020
    Applicant: GRUNENTHAL GMBH
    Inventors: WOLFGANG HELL, OSWALD ZIMMER, HELMUT HEINRICH BUSCHMANN, JOERG HOLENZ, STEFAN GLADOW
  • PROCESS FOR THE PREPARATION OF (1R,2R)-3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL
    Publication number: 20190263747
    Abstract: The present invention relates to a process for the preparation of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol.
    Type: Application
    Filed: May 13, 2019
    Publication date: August 29, 2019
    Applicant: GRUNENTHAL GMBH
    Inventors: WOLFGANG HELL, OSWALD ZIMMER, HELMUT HEINRICH BUSCHMANN, JÖRG HOLENZ, STEFAN GLADOW
  • PROCESS FOR THE PREPARATION OF (1R,2R)-3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL
    Publication number: 20170217875
    Abstract: The present invention relates to a process for the preparation of (1R,2R)-3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol.
    Type: Application
    Filed: April 17, 2017
    Publication date: August 3, 2017
    Inventors: Wolfgang HELL, Oswald ZIMMER, Helmut Heinrich BUSCHMANN, Jörg HOLENZ, Stefan GLADOW
  • PROCESS FOR THE PREPARATION OF (1R,2R)-3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL
    Publication number: 20160221928
    Abstract: The present invention relates to a process for the preparation of (1R,2R)-3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol.
    Type: Application
    Filed: April 12, 2016
    Publication date: August 4, 2016
    Inventors: Wolfgang HELL, Oswald ZIMMER, Helmut Heinrich BUSCHMANN, Jörg HOLENZ, Stefan GLADOW
  • PROCESS FOR THE PREPARATION OF (1R,2R)-3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL
    Publication number: 20140378706
    Abstract: The present invention relates to a process for the preparation of (1R,2R)-3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol.
    Type: Application
    Filed: September 5, 2014
    Publication date: December 25, 2014
    Inventors: Wolfgang HELL, Oswald ZIMMER, Helmut Heinrich BUSCHMANN, Jorg HOLENZ, Stefan GLADOW
  • Process for the preparation of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropy1)-phenol
    Patent number: 8877974
    Abstract: The present invention relates to a process for the preparation of (1R,2R)-3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol.
    Type: Grant
    Filed: July 23, 2007
    Date of Patent: November 4, 2014
    Assignee: Grünenthal GmbH
    Inventors: Wolfgang Hell, Oswald Zimmer, Helmut Heinrich Buschmann, Joerg Holenz, Stefan Gladow
  • 1-Phenyl-2-Dimethylaminomethyl Cyclohexane Compounds And Therapies For Depressive Symptoms, Pain and Incontinence
    Publication number: 20130296414
    Abstract: Metabolites of [2-(3-methoxyphenyl)-cyclohexylmethyl]dimethylamine as free bases and/or in the form of physiologically acceptable salts, corresponding medicaments, the use of [2-(3-methoxyphenyl)-cyclohexylmethyl]-dimethylamine and the metabolites thereof for producing a medicament used for treating depression, and related methods of treating depression, pain and urinary incontinence.
    Type: Application
    Filed: July 3, 2013
    Publication date: November 7, 2013
    Inventors: Elmar FRIDERICHS, Wolfgang STRASSBURGER, Ulrich JAHNEL, Helmut BUSCHMANN, Joerg HOLENZ, Oswald ZIMMER, Derek SAUNDERS, Werner ENGLBERGER, Hagen-Heinrich HENNIES
  • 1-Phenyl-2-DimethylaminomethylCyclohexane Compounds and Therapies for Depressive Symptoms, Pain and Incontinence
    Publication number: 20110263699
    Abstract: Metabolites of [2-(3-methoxyphenyl)-cyclohexylmethyl]dimethylamine as free bases and/or in the form of physiologically acceptable salts, corresponding medicaments, the use of [2-(3-methoxyphenyl)-cyclohexylmethyl]-dimethylamine and the metabolites thereof for producing a medicament used for treating depression, and related methods of treating depression, pain and urinary incontinence.
    Type: Application
    Filed: July 1, 2011
    Publication date: October 27, 2011
    Applicant: GRUENENTHAL GmbH
    Inventors: Elmar Friderichs, Wolfgang Strassburger, Ulrich Jahnel, Derek Saunders, Hagen-Heinrich Hennies, Werner Englberger, Helmut Buschmann, Joerg Holenz, Oswald Zimmer
  • Crystalline salts and/or co-crystals of O-desmethyltramadol
    Publication number: 20110251286
    Abstract: Salts and/or co-crystals of (+)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]-phenol or of (?)-3-[2-(dimethylamino)methyl-1-hydroxy-cyclohexyl]phenol, present in crystalline form, with cinnamic acid, C8- to C10-alkane-monocarboxylic acids, C6- to C10-alkanedicarboxylic acids, C15- to C17-alkane-monocarboxylic acids, fumaric acid, tartaric acid, mandelic acid, hippuric acid and/or embonic acid, a process for their production, and the use of such salts and/or co-crystals as medicaments.
    Type: Application
    Filed: March 9, 2011
    Publication date: October 13, 2011
    Applicant: GRUENENTHAL GmbH
    Inventors: Michael GRUSS, Oswald Zimmer
  • Process for producing 6-dimethylaminomethyl-phenyl-cyclohexane-1,3-diols
    Patent number: 7858826
    Abstract: A process for producing 6-dimethylaminomethyl-1-(3-hydroxy- or 3-C1-C4 alkoxyphenyl)-cyclohexane-1,3-diols from 6-dimethylaminomethyl-1-hydroxy-1-(3-hydroxy- or 3-C1-C4 alkoxyphenyl)-cyclohexane-3-ones by catalytic hydrogenation in the presence of heterogeneous or homogeneous catalysts, or by using metal hydrides.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: December 28, 2010
    Assignee: Gruenenthal GmbH
    Inventors: Wolfgang Hell, Oswald Zimmer, Markus Kegel, Olaf Schaefer, Felix Spindler, Anita Schnyder, Urs Siegrist, Detlef Heller, Hans-Joachim Drexler
  • Process for producing (1RS,3RS,6RS)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol
    Patent number: 7763754
    Abstract: A process for producing (1R,3R,6R)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol or (1S,3S,6S)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol or mixtures thereof.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: July 27, 2010
    Assignee: Gruenenthal GmbH
    Inventors: Helmut Heinrich Buschmann, Wolfgang Hell, Joerg Holenz, Oswald Zimmer, Irene Vaulont, Dieter Haag, Emad El Sayed, Robert Hett, Alfed Olbrich, Lars Pumpenmeier
  • Process for the Preparation of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol
    Publication number: 20100099916
    Abstract: The present invention relates to a process for the preparation of (1R,2R)-3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol.
    Type: Application
    Filed: July 23, 2007
    Publication date: April 22, 2010
    Applicant: Gruenenthal GMBH
    Inventors: Wolfgang Hell, Oswald Zimmer, Helmut Heinrich Buschmann, Joerg Holenz, Stefan Gladow
  • Process for Producing (1RS,3RS,6RS)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol
    Publication number: 20090253936
    Abstract: A process for producing (1R,3R,6R)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol or (1S,3S,6S)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol or mixtures thereof.
    Type: Application
    Filed: February 27, 2009
    Publication date: October 8, 2009
    Applicant: Gruenenthal GmbH
    Inventors: Helmut Heinrich BUSCHMANN, Wolfgang Hell, Joerg Holenz, Oswald Zimmer, Irene Vaulont, Dieter Haag, Emad El Sayed, Robert Hett, Alfed Olbrich, Lars Pumpenmeier
  • Process for Producing 6-Dimethylaminomethyl-phenyl-cyclohexane-1,3-diols
    Publication number: 20090227813
    Abstract: A process for producing 6-dimethylaminomethyl-1-(3-hydroxy- or 3-C1-C4 alkoxyphenyl)-cyclohexane-1,3-diols from 6-dimethylaminomethyl-1-hydroxy-1-(3-hydroxy- or 3-C1-C4 alkoxyphenyl)-cyclohexane-3-ones by catalytic hydrogenation in the presence of heterogeneous or homogeneous catalysts, or by using metal hydrides.
    Type: Application
    Filed: February 27, 2009
    Publication date: September 10, 2009
    Applicant: Gruenenthal GmbH
    Inventors: Wolfgang Hell, Oswald Zimmer, Markus Kegel, Olaf Schaefer, Felix Spindler, Anita Schnyder, Urs Siegrist, Detlef Heller, Hans-Joachim Drexler
  • Saturated and unsaturated heteroarylcycloalkylmethyl amines as anti-depressants
    Patent number: 7384961
    Abstract: Saturated and unsaturated heteroarylcycloalkylmethyl-amine compounds corresponding to formula I, processes for their preparation, pharmaceutical formulations comprising these compounds and the use of saturated and unsaturated heteroarylcycloalkylmethyl-amines for the preparation of pharmaceutical formulations. pharmaceutical formulations and related methods of treatment or prophylaxis of certain condition, especially depression and/or pain, are also disclosed.
    Type: Grant
    Filed: June 20, 2005
    Date of Patent: June 10, 2008
    Assignee: Gruenenthal GmbH
    Inventors: Petra Bloms-Funke, Claudia Puetz, Ivars Graudums, Achim Kless, Carsten Griebel, Hagen-Heinrich Hennies, Dagmar Kaulartz, Sabine Reinardy, Derek Saunders, Klaus Schiene, Bernd Sundermann, Werner Englberger, Oswald Zimmer
  • Substituted amino compounds as 5-HT/NA uptake inhibitors
    Patent number: 7342133
    Abstract: The invention relates to substituted amino compounds, to processes for their preparation, to pharmaceutical formulations containing these compounds and to the use of these substances in the preparation of pharmaceutical formulations, especially for the treatment or inhibition of depression, anxiety, pain and urinary incontinence, and to related methods of treating or inhibiting these disorders.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: March 11, 2008
    Assignee: Gruenenthal GmbH
    Inventors: Petra Bloms-Funke, Elmar Friderichs, Ivars Graudums, Hagen-Heinrich Hennies, Achim Kless, Klaus Schiene, Oswald Zimmer
  • Substituted amino compounds as 5-HT/NA uptake inhibitors
    Publication number: 20070185212
    Abstract: The invention relates to substituted amino compounds, to processes for their preparation, to pharmaceutical formulations containing these compounds and to the use of these substances in the preparation of pharmaceutical formulations, especially for the treatment or inhibition of depression, anxiety, pain and urinary incontinence, and to related methods of treating or inhibiting these disorders.
    Type: Application
    Filed: January 16, 2007
    Publication date: August 9, 2007
    Applicant: Gruenenthal GmbH
    Inventors: Petra Bloms-Funke, Elmar Friderichs, Ivars Graudums, Hagen-Heinrich Hennies, Achim Kless, Klaus Schiene, Oswald Zimmer
  • Process for producing piperidine-2,6 diones heterocyclically substituted in the 3-position
    Publication number: 20070155967
    Abstract: An improved process for producing piperidine-2,6-diones heterocyclically substituted at the 3-position in a minimal number of reaction stages by reacting a 2-aminobenzylamine with a 3-bromoglutarimide to obtain an amine of formula (IV): and thereafter reacting the obtained amine of formula (IV) with a suitable further reactant.
    Type: Application
    Filed: November 28, 2006
    Publication date: July 5, 2007
    Applicant: Gruenenthal Gmbh
    Inventors: Oswald Zimmer, Fritz Theil, Olga Groeger