Patents by Inventor Otto Folkerts

Otto Folkerts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030009782
    Abstract: Compositions and methods for the complete detoxification of fumonisin and fumonisin degradation products are provided. Particularly, nucleotide sequences corresponding to the detoxification enzymes are provided. The sequences find use in preparing expression cassettes for the transformation of a broad variety of host cells and organisms.
    Type: Application
    Filed: June 15, 2001
    Publication date: January 9, 2003
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Jon Duvick, Joyce Maddox, Jacob Gilliam, Otto Folkerts, Oswald R. Crasta
  • Patent number: 6495738
    Abstract: Genes-encoding a delta-9 CoA desaturase from Aspergillus nidulans have been isolated. The proteins encoded by genes, when expressed in a plant, can alter the saturate levels of the oil.
    Type: Grant
    Filed: March 29, 1999
    Date of Patent: December 17, 2002
    Assignee: Dow AgroSciences LLC
    Inventors: Otto Folkerts, Donald J. Merlo
  • Patent number: 6482621
    Abstract: Compositions and methods for the complete detoxification of fumonisin and fumonisin degradation products are provided. Particularly, nucleotide sequences corresponding to the detoxification enzymes are provided. The sequences find use in preparing expression cassettes for the transformation of a broad variety of host cells and organisms.
    Type: Grant
    Filed: October 2, 2000
    Date of Patent: November 19, 2002
    Assignees: Pioneer Hi-Bred International, Inc., CuraGen Corporation
    Inventors: Jon Duvick, Joyce Maddox, Jacob Gilliam, Otto Folkerts, Oswald R. Crasta
  • Patent number: 6433249
    Abstract: Methods for the enhancement of plant disease resistance are provided. The methods comprise transforming said plant with a gene encoding &bgr;-glucosidase and increasing the expression said gene above wild-type levels. Transformed plants, plant cells and seeds are provided. Disease resistant transformed plants, plant cells and seeds are also provided.
    Type: Grant
    Filed: November 1, 1999
    Date of Patent: August 13, 2002
    Assignees: Pioneer Hi-Bred International, Inc., CuraGen Corporation
    Inventors: Jon Duvick, Carl R. Simmons, Oswald R. Crasta, Otto Folkerts
  • Patent number: 6410828
    Abstract: This invention relates to compositions and methods useful in the production of transgenic plants. In particular, the invention relates to maize metallothionein gene transcription regulatory sequences which are useful for directing expression of heterologous DNAs in plant embryo tissue. The invention also relates to expression cassettes containing the promoter sequences and to transgenic plants containing the expression cassettes.
    Type: Grant
    Filed: November 19, 1999
    Date of Patent: June 25, 2002
    Assignee: Dow AgroSciences LLC
    Inventors: Katherine Armstrong, Aaron T. Woosley, Dayakar R. Pareddy, Beth C. Rubin-Wilson, Timothy D. Hey, Kelley A. Smith, Otto Folkerts
  • Publication number: 20020068359
    Abstract: The maize myo-inositol-1-phosphate synthase (MIP synthase)gene and novel embryo specific regulatory sequences derived from the MIP synthase gene are useful in plant genetic engineering.
    Type: Application
    Filed: December 1, 2000
    Publication date: June 6, 2002
    Inventors: Katherine Armstrong, Timothy D. Hey, Otto Folkerts, Kelley A. Smith, Nicole L. Hopkins
  • Patent number: 6388171
    Abstract: Compositions and methods for the complete detoxification of fumonisin and fumonisin degradation products are provided. Particularly, nucleotide sequences corresponding to the detoxification enzymes are provided. The sequences find use in preparing expression cassettes for the transformation of a broad variety of host cells and organisms.
    Type: Grant
    Filed: July 12, 1999
    Date of Patent: May 14, 2002
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Jon Duvick, Joyce Maddox, Jacob Gilliam, Otto Folkerts, Oswald R. Crasta
  • Patent number: 6384207
    Abstract: Regulatory sequences derived from a maize root preferential cationic peroxidase gene (Per5), including the promoter, introns, and the 3′ untranslated region, are useful to control expression of recombinant genes in plants.
    Type: Grant
    Filed: June 12, 1998
    Date of Patent: May 7, 2002
    Assignee: Dow AgroSciences LLC
    Inventors: Michael Ainley, Katherine Armstrong, Scott Belmar, Otto Folkerts, Nicole Hopkins, Michael A. Menke, Dayakar Pareddy, Joseph F. Petolino, Kelley Smith, Aaron Woosley
  • Patent number: 6350934
    Abstract: The present invention relates to nucleic acid molecules encoding delta 9 desaturase gene, and expression vectors, plant cells, and transgenic plants expressing delta 9 desaturase nucleic acid. The nucleic acid molecules of the present invention can be used, for example, to decrease delta 9 desaturase activity in plant cells, resulting in decreased unsaturated fatty acid production.
    Type: Grant
    Filed: July 12, 1996
    Date of Patent: February 26, 2002
    Assignees: Ribozyme Pharmaceuticals, Inc., DowElanco
    Inventors: Michael G. Zwick, Brent E. Edington, James A. McSwiggen, Patricia Ann Owens Merlo, Lining Guo, Thomas A. Skokut, Scott A. Young, Otto Folkerts, Donald J. Merlo
  • Patent number: 6331664
    Abstract: Genes encoding maize oleoyl-ACP and palmitoyl-ACP thioesterase enzymes have been isolated from maize. These genes, when expressed in a plant, can be used to create transgenic plants having altered palmitic acid oil profiles.
    Type: Grant
    Filed: April 22, 1998
    Date of Patent: December 18, 2001
    Assignee: Dow AgroSciences LLC
    Inventors: Beth Rubin-Wilson, Lining Guo, Tom Skokut, Scott Young, Otto Folkerts, Katherine Armstrong, Neil M. Cowen
  • Patent number: 6323395
    Abstract: Genes encoding &bgr;-Ketoacyl-Acyl Carrier Protein Synthase II have been isolated from maize and soybean tissues. These proteins, when expressed in a plant, can alter the saturate levels of the oil.
    Type: Grant
    Filed: December 16, 1998
    Date of Patent: November 27, 2001
    Assignee: Dow AgroSciences LLC
    Inventors: Beth C. Rubin-Wilson, Scott A. Young, Otto Folkerts
  • Patent number: 6211435
    Abstract: The present invention provides polynucleotides and related polypeptides of the enzyme APAO isolated from Exophiala spinifera. Additionally, the polynucleotide encoding for the APAO enzyme can be used to transform plant cells normally susceptible to Fusarium or other toxin-producing fungus infection. Plants can be regenerated from the transformed plant cells. Additionally, the present invention provides for expressing both APAO and a fumonisin esterase in a transgenic plant. In this way, a transgenic plant can be produced with the capability of degrading fumonisin, as well as with the capability of producing the degrading enzymes. In addition, the present invention provides methods for producing the APAO enzyme in both prokaryotic and non-plant eukaryotic systems. Methods for detoxification in grain, grain processing, silage, food crops and in animal feed and rumen microbes are also disclosed.
    Type: Grant
    Filed: July 12, 1999
    Date of Patent: April 3, 2001
    Assignees: Pioneer Hi-Bred International, Inc., CuraGen Corporation
    Inventors: Jonathan P. Duvick, Jacob T. Gilliam, Joyce R. Maddox, Oswald R. Crasta, Otto Folkerts
  • Patent number: 6166302
    Abstract: Synthetic DNA sequences which are optimized for expression in plants, particularly maize, and which encode a Bacillus thuringiensis protein that is toxic to specific insects are provided, along with methods for the engineering of any synthetic insecticidal gene in maize.
    Type: Grant
    Filed: October 11, 1996
    Date of Patent: December 26, 2000
    Assignee: Dow AgroSciences LLC
    Inventors: Donald J. Merlo, Otto Folkerts