Abstract: For position sensors, e.g., a fiber-based system, that build a shape of an elongated member, such as a catheter, using a sequence of small orientation measurements, a small error in orientation at the proximal end of the sensor will cause large error in position at distal points on the fiber. Exemplary methods and systems are disclosed, which may provide full or partial registration along the length of the sensor to reduce the influence of the measurement error. Additional examples are directed to applying selective filtering at a proximal end of the elongated member to provide a more stable base for distal measurements and thereby reducing the influence of measurement errors.

Abstract: A system for measuring a heat response of a battery cell includes a cell chamber configured to receive the battery cell therein. The cell chamber is configured to trigger a battery cell into a thermal runaway event while in the cell chamber, which causes the battery cell to eject an electrode winding, particles, and gas. The system also includes an ejecta bore muffler configured to receive the electrode winding, the particles, and the gas. The system also includes an ejecta basket configured to be positioned at least partially within the ejecta bore muffler. The ejecta basket is configured to capture the electrode winding while allowing at least a portion of the particles, the gas, or both to pass therethrough. The system also includes a gas collection system configured to receive at least a portion of the gas that passes through the ejecta basket.

Abstract: A method of clamping a voltage includes providing a fin-based field effect transistor (FinFET) device. The FinFET device includes an array of FinFETs. Each FinFET includes a source contact electrically coupled to a fin and a gate contact. The method also includes applying the voltage to the source contact and applying a second voltage to the gate contact. The voltage is greater than the second voltage. The method further includes increasing the voltage to a threshold voltage and conducting current from the source contact to the gate contact in response to the voltage reaching the threshold voltage.

Abstract: A system including: a distance sensor system located/oriented/configured to measure a deformation of a geomaterial portion due to compaction of the geomaterial portion; and an electronic processing system configured to: receive signals from the distance sensor system representing the measured deformation, and automatically generate an estimate/measure of a geomaterial layer property of the geomaterial portion based on: the measured deformation; and a pre-defined relationship/model that associates deformation values with geomaterial layer property values (e.g., density values, stiffness values, modulus values, energy values, or layer thicknesses during compaction).

Abstract: Autonomous localized permeability material systems are provided that can include: a dynamically permeable porous material; and immobilized reagents operatively associated with the porous material in sufficient proximity to trigger a localized change in material pore size upon reagent reaction. Methods for preparing these materials are also provided as well as methods for autonomously modifying localized permeability of material.

Abstract: A system and method are provided for super-resolution imaging beyond the Rayleigh spatial resolution limit of an optical system. In the context of a system, first and second pinhole assemblies are configured to be controllably positioned. The first and second pinhole assemblies define respective pinholes and being configured to be backlit. The system also includes a collimating lens configured to collimate at least a portion of the signals passing through the respective pinholes of the first and second pinhole assemblies. The system further includes an amplitude/phase mask configured to provide amplitude and phase modulation to signals received from the collimating lens and an imaging lens configured to focus the signals received from the amplitude/phase mask upon an image plane to permit objects to be separately identified.

Abstract: For position sensors, e.g., a fiber-based system, that build a shape of an elongated member, such as a catheter, using a sequence of small orientation measurements, a small error in orientation at the proximal end of the sensor will cause large error in position at distal points on the fiber. Exemplary methods and systems are disclosed, which may provide full or partial registration along the length of the sensor to reduce the influence of the measurement error. Additional examples are directed to applying selective filtering at a proximal end of the elongated member to provide a more stable base for distal measurements and thereby reducing the influence of measurement errors.

Abstract: A hierarchical catalyst composition comprising a continuous or particulate macroporous scaffold in which is incorporated mesoporous aggregates of magnetic nanoparticles, wherein an enzyme is embedded in mesopores of the mesoporous aggregates of magnetic nanoparticles. Methods for synthesizing the hierarchical catalyst composition are also described. Also described are processes that use the recoverable hierarchical catalyst composition for depolymerizing lignin, remediation of water contaminated with aromatic substances, polymerizing monomers by a free-radical mechanism, epoxidation of alkenes, halogenation of phenols, inhibiting growth and function of microorganisms in a solution, and carbon dioxide conversion to methanol.

Abstract: Disclosed is a method of forming a composite door. A precursor frame sheet, comprising flaps, is formed by cutting a prepreg sheet. The precursor frame sheet is draped over a door-forming tool, comprising a frame face and flap supports, non-parallel to the frame face, such that each of the flaps of the precursor frame sheet is geometrically complementary with a corresponding one of the flap supports. A composite frame is formed by curing the precursor frame sheet, draped over the door-forming tool, wherein the composite frame comprises a first rail and a second rail. The composite frame is separated from the door-forming tool. The composite frame, first composite edge fittings, second composite edge fittings, a first composite side beam, a second composite side beam, and a composite skin are interconnected.

Abstract: Systems and methods for forming and displaying an analyte location map is provided. The system includes a detector, a display device, and a controller. The detector is configured to measure concentration of an analyte and output a signal based on the measured concentration of the analyte. The controller includes a first location module, a second location module, a mapping module, and a presentation module. The mapping module is configured to generate 3D data of an area, generate analyte location data based on the signal from the detector and tracked 3D location of the detector, and combine the 3D data and the analyte location data to form an analyte location map. The presentation module is configured to display the analyte location map on the display device based on the tracked 3D location of the display device.

Abstract: The present application is related to devices, systems, and methods for controlling active drive systems. In one embodiment, the drive system may include a first surface and a second surface for engaging an elongate member. The first and second surfaces may be attached to a drive mechanism to move the elongate member. The first surface may be slidable relative to the drive mechanism and may have a clearance between the drive mechanism and an end of the first surface during movement of the elongate member in a non-slip condition. A sensor may be associated with the first surface and may be configured to detect movement of the first surface in a slip condition.

Abstract: A rotary electric machine arranged as a brushless electric ring motor is described and includes a rotor that is disposed within a stator and arranged to rotate on a guide element. The rotor has a plurality of ferritic elements arranged on an outer surface, and the stator is an annular device having a plurality of electro-magnetic elements arranged on an inner portion between first and second flanges. The first and second flanges both include an annular ring that is fabricated from a non-magnetic material and has a plurality of ferromagnetic elements. The ferromagnetic elements are magnetically coupled to corresponding ones of the electro-magnetic elements to exert magnetic force on the ferritic elements of the rotor when the electro-magnetic elements are activated. The rotary electric machine may operate as a first thrust generating system that is upstream of a second thrust generating system for a turbojet engine.

Abstract: The invention provides a method of diagnosing Non-Alcoholic Steatohepatitis (NASH) and/or the hepatic fibrosis status of a subject, especially a subject afflicted with Non-alcoholic fatty liver disease (NAFLD) or NASH, based on the level of only three or more particular biomarkers. The invention further provides a kit suitable for performing said method and the use of said method and methods of treating patients diagnosed in accordance with the disclosed methods.

Abstract: Systems and methods for introducing and driving flexible members in a patient's body are described herein. In one embodiment, a robotic method includes positioning a flexible elongated member that has a preformed configuration, wherein at least a part of the flexible elongated member has a first member disposed around it, and wherein the first member includes a first wire for bending the first member or for maintaining the first member in a bent configuration, releasing at least some tension in the first wire to relax the first member, and advancing the first member distally relative to the flexible elongated member while the first member is in a relaxed configuration.

Abstract: Disclosed are compositions that comprise one or more broad-spectrum capture molecules (including, for example, the small, homodimer-forming lectin protein, Griffithsin), or glycoproteins that coat the viral envelope surface in methods for the identification of one or more virus particles in an airborne, aerosol, or aerosolized sample. Also disclosed are methods for the use of such capture agents in the manufacture of diagnostic reagents (as well as kits, devices, and systems comprising them), useful in developing viral detection platforms that are both rapid and facile to perform, yet highly-sophisticated, accurate, and sensitive. Methods are also provided for using these compositions in the identification, molecular capture, characterization, and design of therapeutic regents related thereto for the treatment of one or more symptoms of a viral infection, or a virally-induced disease in mammals and, particularly, in humans.

Abstract: Pharmaceutical formulations that can include at least one genetically modified OPH enzyme are provided. Methods for treating chemical warfare agent exposure are also provided. Modified biomolecules are also provided.

Abstract: The present application is related to devices, systems, and methods for controlling active drive systems. In one embodiment, the drive system may include a first surface and a second surface for engaging an elongate member. The first and second surfaces may be attached to a drive mechanism to move the elongate member. The first surface may be slidable relative to the drive mechanism and may have a clearance between the drive mechanism and an end of the first surface during movement of the elongate member in a non-slip condition. A sensor may be associated with the first surface and may be configured to detect movement of the first surface in a slip condition.

Abstract: Connection systems for injection devices are disclosed. Also disclosed are injection devices and methods of using the same. A connection system includes a first and second connection assembly and a coupling assembly to secure the same. The first connection assembly connects to a medicament container, and the second connection assembly has a needle movable toward the medicament container. Removable flexible barriers are disposed on the first and second connection assemblies and can be removed once the connection assemblies are coupled together to form an aseptic connection between the two assemblies. The needle can be moved toward the medicament container to pierce a septum on the container to form a fluid communication between the container and the needle.

Abstract: Certain aspects of the present disclosure provide techniques for an aerodynamic surface actuation system, including: a middle track connected to an aerodynamic surface and configured to move along a plurality of intermediate tracks, wherein one or more inner surfaces of the middle track are configured to interface with one or more outer surfaces of the plurality of intermediate tracks; a plurality of outer tracks, each including a flange and configured to interface with one or more inner surfaces of the plurality of intermediate tracks; and an actuator configured to control a position of the middle track and a position of the plurality of intermediate tracks via a plurality of linkages.

Abstract: The invention provides a method of diagnosing Non-Alcoholic Steatohepatitis (NASH) and/or the hepatic fibrosis status of a subject, especially a subject afflicted with Non-alcoholic fatty liver disease (NAFLD) or NASH, based on the level of only three or more particular biomarkers. The invention further provides a kit suitable for performing said method and the use of said method and methods of treating patients diagnosed in accordance with the disclosed methods.