Abstract: Disclosed herein are Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) 9-based system related compositions and methods of using said CRISPR/Cas9-based system related compositions for altering gene expression and genome engineering. Also disclosed herein are compositions and methods of using said compositions for altering gene expression and genome engineering in muscle, such as skeletal muscle and cardiac muscle.

Abstract: Disclosed herein are Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) 9-based system related compositions and methods of using said CRISPR/Cas9-based system related compositions for altering gene expression and genome engineering. Also disclosed herein are compositions and methods of using said compositions for altering gene expression and genome engineering in muscle, such as skeletal muscle and cardiac muscle.

Abstract: According to an example aspect of the present invention, there is provided a method, comprising: generating, based on source media content, a media vector comprising one or more privacy-controlled components, wherein each component is a partially modified version of the source media content such that at least some different privacy-controlled visual media content parts of the source media content are removed, substituted or hidden at different privacy-controlled components, and assigning for each of the components privacy control information.

Abstract: Disclosed herein are Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) 9-based system related compositions and methods of using said CRISPR/Cas9-based system related compositions for altering gene expression and genome engineering. Also disclosed herein are compositions and methods of using said compositions for altering gene expression and genome engineering in muscle, such as skeletal muscle and cardiac muscle.

Abstract: Disclosed herein are Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) 9-based system related compositions and methods of using said CRISPR/Cas9-based system related compositions for altering gene expression and genome engineering. Also disclosed herein are compositions and methods of using said compositions for altering gene expression and genome engineering in muscle, such as skeletal muscle and cardiac muscle.

Abstract: A metallic foil for lightning strike protection in a composite aerospace structure having a length, a width, and a thickness of not more than 30 microns. There are a plurality of pores of a predefined geometric shape extending through the thickness of the metallic foil and being distributed across a surface area defined by the length and the width of the metallic foil. The plurality of pores in the aggregate define an open area of not more than 40% of the surface area and the metallic foil has a weight of not more than 115 g/m2. The metallic foil has a weight to conductivity ratio of not more than 0.40 gram-ohms per square.

Abstract: The present invention relates to the detection of malicious software in electronic documents and comprises: detecting an executable code in the electronic document provided to a client module; extracting information from the electronic document comprising the executable code and metadata of the electronic document; creating a binary vector associated with the electronic document; comparing, in a classifier module (200), the binary vector with one or more groups of vectors previously classified and stored in a database (400); classifying the vector in one of the groups, where each group has associated therewith a verdict about the presence of malicious software; and determining that the document contains malicious software depending on the verdict associated with the group in which its associated vector has been classified.

Abstract: A metallic foil for lightning strike protection in a composite aerospace structure having a length, a width, and a thickness of not more than 30 microns. There are a plurality of pores of a predefined geometric shape extending through the thickness of the metallic foil and being distributed across a surface area defined by the length and the width of the metallic foil. The plurality of pores in the aggregate define an open area of not more than 40% of the surface area and the metallic foil has a weight of not more than 115 g/m2. The metallic foil has a weight to conductivity ratio of not more than 0.40 gram-ohms per square.

Abstract: The invention relates to a method intended to provide or collect additional information concerning the content of a broadcast. For this purpose, it is necessary to design a process for synchronising between a reference audiovisual content and an altered television broadcast version thereof. The method comprises the steps of: creating a fingerprint of the broadcast content by means of the real-time extraction of features of the image which correspond to a series of frames; parcelling the image, that is dividing the screen corresponding to a frame of the broadcast into smaller pieces or parcels; extracting the colour histogram corresponding to each parcelled piece; searching for significant points of the image of each frame analysed; detecting the advertisement broadcast period; and comparing the fingerprint created for the broadcast content with the fingerprint created for the reference content, to achieve a degree of coincidence or certainty or correspondence below a threshold.

Abstract: Systems and methods detect and prevent changes in business applications that modify its state to non-secure and/or non-compliant. A system may include a processor set up to perform: defining a compliant state of a computer software configuration, monitoring a state of the computer software configuration, detecting a change in the state of the computer software configuration, wherein the change causes a changed state, and comparing the compliant state and the changed state, wherein if the changed state conflicts with the compliant state, stopping the change.

Abstract: The present invention relates to the combination of organic acid salts with at least one active ingredient of plant origin, preferably essential oils, partially protected with vegetable fats and/or oils, which prevent these active ingredients from being digested by stomach enzymes during the digestive process. The sodium salts of short-chain acids, preferably salts of butyric, acid are preferred. The preferred essential oils are ginger, piperine, oregano, garlic, thymol, carvacrol, cinnamaldehyde and/or any combinations thereof. The combination of organic acid salts and the essential oils protected with vegetable fats and/or oils, are used as powerful promoters or stimulants for animal growth, as organic bactericides against pathogenic bacteria present in said animals and as modulators of immune response thereof.

Abstract: A metallic foil for lightning strike protection in a composite aerospace structure having a length, a width, and a thickness of not more than 30 microns. There are a plurality of pores of a predefined geometric shape extending through the thickness of the metallic foil and being distributed across a surface area defined by the length and the width of the metallic foil. The plurality of pores in the aggregate define an open area of not more than 40% of the surface area and the metallic foil has a weight of not more than 115 g/m2. The metallic foil has a weight to conductivity ratio of not more than 0.40 gram-ohms per square.

Abstract: The invention relates to a coating consisting essentially of titanium dioxide wherein at least 20% of the titanium dioxide has a crystalline structure of anatase and/or rutile; the coating has a roughness comprising indentations, wherein at least 50% of the indentations have a maximum depth of 1-50 nm and a maximum width of 1-50 nm; the coating is treatable to achieve a water contact angle of 0-20°; the coating is treatable to be negatively charged or positively charged; and the coating exhibits an improved attachment of mammalian tissue cells, which improved attachment is such that when a substrate coated with the above coating is compared to the same uncoated substrate, at least 100% more cells remain attached on the coated substrate than on the uncoated substrate.

Abstract: A system is configured for real time detection and prevention of segregation of duties violations in business-critical applications. The system includes a software application monitor, a Segregation of Duties (SoD) conflict detection engine, a processor and a memory. The software application monitor configured to monitor an action executed by a user in the software application in real-time. The SoD conflict detection engine receives an action notification from the software application monitor having an action and an associated user, and determines whether the action is associated with a conflict in a conflict rule database. The engine looks up the user and action and determines if the user has permission to execute the action and/or if the user has previously executed the action, and if so outputs a preventive alert indicating a segregation of duties violation.

Abstract: Disclosed herein are Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) 9-based system related compositions and methods of using said CRISPR/Cas9-based system related compositions for altering gene expression and genome engineering. Also disclosed herein are compositions and methods of using said compositions for altering gene expression and genome engineering in muscle, such as skeletal muscle and cardiac muscle.

Abstract: The present disclosure provides vectors and methods for rapid and efficient integration of DNA at target sites in genomes with high efficiency. The present disclosure also provides methods for creating cell lines to model human diseases, for activating gene expression to correct genetic diseases or even for performing genetic screenings.

Abstract: Disclosed herein are compositions of transcription activator-like effectors transcription factors and methods of using said compositions for inducing gene expression of mammalian genes.

Abstract: The present invention relates to the combination of organic acid salts with at least one active ingredient of plant origin, preferably essential oils, partially protected with vegetable fats and/or oils, which prevent these active ingredients from being digested by stomach enzymes during the digestive process. The sodium salts of short-chain acids, preferably salts of butyric, acid are preferred. The preferred essential oils are ginger, piperine, oregano, garlic, thymol, carvacrol, cinnamaldehyde and/or any combinations thereof. The combination of organic acid salts and the essential oils protected with vegetable fats and/or oils, are used as powerful promoters or stimulants for animal growth, as organic bactericides against pathogenic bacteria present in said animals and as modulators of immune response thereof.

Abstract: Disclosed herein are compositions of transcription activator-like effectors transcription factors and methods of using said compositions for inducing gene expression of mammalian genes.

Abstract: A procedure to broadcast digital multimedia contents to subscribers, where a first digital data transport stream broadcast to subscribers from a head end (12) via a first telecommunications network other than a telecommunications network based on an Internet IP protocol is received in a customer device (15); transmission from a first retransmission unit (153) of a lost packet petition message to a second retransmission unit (132) contained in a service application unit (13) connectable to the customer device (15) via a second telecommunications network (11) based on an Internet IP protocol; in response to the lost packet petition message from the first data transport stream, transmission of a second digital data stream that comprises at least one packet lost form the first digital data transport stream.