Patents by Inventor Palaniyandi Manivasakam

Palaniyandi Manivasakam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AUTOPHAGY ACTIVATORS AND INHIBITORS OF FERROPTOSIS FOR PREVENTING ACUTE RENAL FAILURE AND NEUROTOXCITY INDUCED BY CERTAIN ANTIBIOTICS
    Publication number: 20210369669
    Abstract: The present disclosure relates to pharmaceutical compositions, pharmaceutical combinations and methods of treatment including zileuton, edaravone and atorvastatin compounds combined with nephrotoxicity-inducing antibiotic or anticancer drugs for treating bacterial infections and cancers.
    Type: Application
    Filed: October 18, 2019
    Publication date: December 2, 2021
    Applicant: SystaMedic Inc.
    Inventors: Anton Franz Joseph FLIRI, Palaniyandi MANIVASAKAM, Joyce SUTCLIFFE
  • NOVEL COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY DISEASES
    Publication number: 20210251934
    Abstract: Anti-inflammatory compositions that merely treat symptoms of inflammation and not its root causes have frequently been shown to impair healing processes and exacerbate disease. The present disclosure includes novel compositions, combinations and methods of treatment that overcome this shortcoming by down regulating excessive inflammation and by activating cellular functions supporting healing processes.
    Type: Application
    Filed: April 15, 2021
    Publication date: August 19, 2021
    Applicant: SystaMedic Inc.
    Inventors: Anton F. Fliri, Shama Kajiji, Palaniyandi Manivasakam
  • NOVEL COMPOSITIONS OF COMBINATIONS OF NON-COVALENT DNA BINDING AGENTS AND ANTI-CANCER AND/OR ANTI-INFLAMMATORY AGENTS AND THEIR USE IN DISEASE TREATMENT
    Publication number: 20180042938
    Abstract: The invention provides for compositions for treating a cancer or an inflammatory disorder comprising a combination of agents in a pharmaceutically acceptable carrier, wherein said agents comprise: (i) a non-covalent DNA binding agent; and (ii) an anti-cancer or anti-inflammatory agent.
    Type: Application
    Filed: June 16, 2017
    Publication date: February 15, 2018
    Inventors: Pravin R. Chaturvedi, Palaniyandi Manivasakam, Steven Grossman, Sharon Cantor
  • Compositions of combinations of non-covalent DNA binding agents and anti-cancer and/or anti-inflammatory agents and their use in disease treatment
    Patent number: 9744175
    Abstract: The invention provides for compositions for treating a cancer or an inflammatory disorder comprising a combination of agents in a pharmaceutically acceptable carrier, wherein said agents comprise: (i) a non-covalent DNA binding agent; and (ii) an anti-cancer or anti-inflammatory agent.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: August 29, 2017
    Assignee: INDUS PHARMACEUTICALS, INC.
    Inventors: Pravin R. Chaturvedi, Palaniyandi Manivasakam, Steven Grossman, Sharon Cantor
  • NOVEL COMPOSITIONS OF COMBINATIONS OF NON-COVALENT DNA BINDING AGENTS AND ANTI-CANCER AND/OR ANTI-INFLAMMATORY AGENTS AND THEIR USE IN DISEASE TREATMENT
    Publication number: 20150056192
    Abstract: The invention provides for compositions for treating a cancer or an inflammatory disorder comprising a combination of agents in a pharmaceutically acceptable carrier, wherein said agents comprise: (i) a non-covalent DNA binding agent; and (ii) an anti-cancer or anti-inflammatory agent.
    Type: Application
    Filed: February 28, 2013
    Publication date: February 26, 2015
    Inventors: Pravin R. Chaturvedi, Palaniyandi Manivasakam, Steven Grossman, Sharon Cantor
  • METHODS AND REAGENTS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS
    Publication number: 20120058979
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Application
    Filed: November 9, 2011
    Publication date: March 8, 2012
    Applicant: Zalicus Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant R. Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley, Michael S. Slavonic, Brendan Smith, Benjamin A. Auspitz
  • Methods and reagents for the treatment of immunoinflammatory disorders
    Patent number: 8080553
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: December 20, 2011
    Assignee: Zalicus Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant R. Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley, Michael S. Slavonic, Brendan Smith, Benjamin A. Auspitz
  • COMBINATIONS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS
    Publication number: 20110223621
    Abstract: The invention features pharmaceutical compositions that include dipyridamole and a corticosteroid.
    Type: Application
    Filed: March 15, 2011
    Publication date: September 15, 2011
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole W. Hurst, Michael A. Foley
  • Combinations for the treatment of immunoinflammatory disorders
    Patent number: 7915265
    Abstract: The invention features pharmaceutical compositions that include dipyridamole and a corticosteroid.
    Type: Grant
    Filed: February 15, 2006
    Date of Patent: March 29, 2011
    Assignee: Zalicus Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole W. Hurst, Michael A. Foley
  • METHODS AND REAGENTS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20100210606
    Abstract: The invention features a method for treating an immunoinflammatory administering a compound of formula (I), e.g., ibudilast or KC-764, alone or in combination with a corticosteroid, tetra-substituted pyrimidopyrimidine, or other compound. The invention also features pharmaceutical compositions including the combination above for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: May 3, 2010
    Publication date: August 19, 2010
    Inventors: Edward Roydon Jost-Price, Palaniyandi Manivasakam, Brendan Smith, Michael S. Slavonic, Benjamin A. Auspitz
  • COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20100173881
    Abstract: The invention features methods and compositions for the treatment of immunonflammatory disorders.
    Type: Application
    Filed: January 22, 2010
    Publication date: July 8, 2010
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmerrmann, Curtis Keith, Alexis Borisy
  • Methods and reagents for the treatment of inflammatory disorders
    Patent number: 7709495
    Abstract: The invention features a method for treating an immunoinflammatory administering a compound of formula (I), e.g., ibudilast or KC-764, alone or in combination with a corticosteroid, tetra-substituted pyrimidopyrimidine, or other compound. The invention also features pharmaceutical compositions including the combination above for the treatment or prevention of an immunoinflammatory disorder.
    Type: Grant
    Filed: November 19, 2004
    Date of Patent: May 4, 2010
    Assignee: CombinatoRx, Incorporated
    Inventors: Edward Roydon Jost-Price, Palaniyandi Manivasakam, Brendan Smith, Michael S. Slavonic, Benjamin A. Auspitz
  • Methods and Reagents for the Treatment of Inflammatory Disorders
    Publication number: 20090075951
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a tricyclic compound and, optionally, a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing a tricyclic compound and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: November 20, 2008
    Publication date: March 19, 2009
    Applicant: CombinatoRx, Inc.
    Inventors: Benjamin A. Auspitz, Alexis Borisy, Jason Fong, Nicole Hurst, Edward Roydon Jost-Price, Curtis T. Keith, Palaniyandi Manivasakam, Robyn Sackeyfio, Michael S. Slavonic, Brendan Smith, Grant R. Zimmermann
  • COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20080280863
    Abstract: The invention features methods and compositions for the treatment of immunoinflammatory disorders.
    Type: Application
    Filed: February 25, 2008
    Publication date: November 13, 2008
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Combinations for the treatment of inflammatory disorders
    Patent number: 7335371
    Abstract: The invention features methods and compositions for the treatment of immunonflammatory disorders.
    Type: Grant
    Filed: November 19, 2003
    Date of Patent: February 26, 2008
    Assignee: CombinatoRx, Incorporated
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Combinations for the treatment of rheumatoid arthritis
    Publication number: 20070259841
    Abstract: The invention features a method for treating a patient diagnosed with rheumatoid arthritis by systemically administering an azole and a steroid to the patient. The invention also features a pharmaceutical composition containing an azole and a steroid for the treatment of rheumatoid arthritis.
    Type: Application
    Filed: June 13, 2007
    Publication date: November 8, 2007
    Applicant: CombinatoRx, Incorporated
    Inventors: Jason Fong, Edward Jost-Price, Curtis Keith, Palaniyandi Manivasakam, Robyn Sackeyfio, Grant Zimmermann
  • Combinations for the treatment of immunoinflammatory disorders
    Patent number: 7253155
    Abstract: The invention features a method for treating a patient having an immunoinflammatory disorder, by administering to the patient (i) a tetra-substituted pyrimidopyrimidine, and (ii) a corticosteroid simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit immunoinflammation.
    Type: Grant
    Filed: October 4, 2002
    Date of Patent: August 7, 2007
    Assignee: CombinatoRx, Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmerman, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley
  • Combination therapy for the treatment of immunoinflammatory disorders
    Publication number: 20070110685
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a non-steroidal immunophilin-dependent immunosuppressant (NsIDI) and a Group A enhancer (e.g., antifungal agent, antigout agent, anti-infective agent, antiprotozoal agent, antiviral agent, humectant, sunscreen, vitamin D compound, microtubuline inhibitor, or zinc salt) or analog or metabolite thereof to the patient. The invention also features a pharmaceutical composition containing an NsIDI and Group A enhancer or analog or metabolite thereof for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: June 16, 2006
    Publication date: May 17, 2007
    Inventors: Benjamin Auspitz, Bradley Brasher, Todd Chappell, Michael Frank, Daniel Grau, Edward Jost-Price, Seth Lederman, Palaniyandi Manivasakam, Seth Orlow, Noah Sachs, Brendan Smith
  • Methods and reagents for the treatment of immunoinflammatory disorders
    Publication number: 20070010502
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Application
    Filed: September 7, 2006
    Publication date: January 11, 2007
    Applicant: CombinatoRx Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael Foley, Michael Slavonic, Brendan Smith, Benjamin Auspitz
  • Combinations for the treatment of immunoinflammatory disorders
    Publication number: 20060234991
    Abstract: The invention features pharmaceutical compositions that include dipyridamole and a corticosteroid.
    Type: Application
    Filed: February 15, 2006
    Publication date: October 19, 2006
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael Foley