Abstract: Disclosed are a display panel and a display device having same. The display panel includes an array substrate including a base substrate, and thin film transistors, first signal lines extending in a first direction and spaced apart in a second direction, second signal lines extending in a second direction and spaced apart in the first direction, and metal blocks spaced apart in the first direction, which are arranged on the base substrate. The orthographic projections of the first signal lines on the base substrate intersect with the orthographic projections of the second signal lines on the base substrate; the orthographic projections of the metal blocks on the base substrate overlap the orthographic projections of the first signal lines on the base substrate; and the orthographic projections of the metal blocks on the base substrate do not overlap the orthographic projections of the second signal lines on the base substrate.

Abstract: A compound having a structure of formula II-3 or a pharmaceutically acceptable salt thereof are provided. In formula II-3, Y is CH; R1 and R2 are independently hydrogen, deuterium, halogen, C1-C6 alkyl, C1-C6 haloalkyl, hydroxy-substituted C1-C6 alkyl, cyano, nitro, —ORa, NRaRb, —SRa, —C(O)ORa, —C(O)Ra, —C(O)NRaRb, —NRaC(O)Ra, —S(O)3Ra, or —S(O)2Ra; or R1 and R2, together with an atom, form a 5-6-membered saturated ring or a 5-6-membered unsaturated ring, where the 5-6-membered saturated ring or the 5-6-membered unsaturated ring comprises 0, 1, or 2 heteroatoms selected from O, S, and N; where R4 is hydrogen, deuterium, halogen, or C1-C6 alkyl; where R5 is C1-C6 alkyl; where Ra and Rb are independently hydrogen or C1-C6 alkyl.

Abstract: A display panel and a display apparatus, including a light emitting structure layer (12), the light emitting structure layer (12) includes a pixel define layer (122). The pixel define layer (122) includes a first dam portion (201) and a second dam portion (202). The first dam portion (201) and the second dam portion (202) are formed a plurality of pixel openings, a distance between a surface of a side of the first dam portion (201) away from the base substrate (10) and a surface of a side of the planarization layer away from the base substrate (10) is smaller than a distance between a surface of a side of the second dam portion (202) away from the base substrate (10) and a surface of a side of the planarization layer away from the base substrate (10).

Abstract: The present disclosure relates to a process of treating a crude pyrolysis product, comprising: (1) providing the crude pyrolysis product; and (2) contacting the crude pyrolysis product with an upgrading catalyst at a temperature in the range of from 300° C. to 600° C., to obtain a refined pyrolysis product. The present disclosure further relates to the refined pyrolysis product and the use thereof as a raw material in a steam-cracking process.

Abstract: In some implementations, one or more computing devices may generate a first layer of a hierarchical workflow. The one or more computing devices may generate a second layer of a hierarchical workflow configured to:? receive a first output from the first layer as an indication of a first state of the first layer; provide an indication of an error associated with the first output; and? receive a second output, as an indication of a second state of the first layer, from the first layer. The second output may be revised from the first output based at least in part on the indication of the error? or the second output may be the same as the first output after correcting performance of one or more operations at the first layer.

Abstract: Provided is a compound having anti-tumor activity and a use thereof. As a PRMT5 inhibitor, the compound has a structure represented by formula (I). Experiments have confirmed that these compounds have strong inhibitory effects on PRMT5 enzyme activity and tumor cell growth, and can be used as promising compounds for treating PRMT5-mediated diseases. Furthermore, a specific synthesis method is further studied. The synthesis method is simple in process, convenient to operate, and beneficial to large-scale industrial production and application.

Abstract: Resource optimized forwarding of classified requests to different instances of a microservice is provided. The process includes obtaining classified requests to a microservice. The classified requests are classified based on different microservice resource consumption types. Further, the method includes forwarding the classified requests to instances of the microservice with different assigned resource configurations. The forwarding is based on the different microservice resource consumption types of the classified requests.

Abstract: A display substrate includes: a base, and pixel units arranged in an array, each pixel unit including at least two sub-pixels each including: a pixel driving circuit, and a light-emitting element. The light-emitting element includes: a first electrode, a light-emitting layer, and a second electrode arranged on the base sequentially. Each sub-pixel is configured with a corresponding operating voltage transmission line. The pixel driving circuit includes: a driving transistor with a first pole electrically connected to the operating voltage transmission line. Each pixel unit includes two first sub-pixels, one second sub-pixel, and one third sub-pixel. The first operating voltage transmission line is configured to transmit a first operating voltage to both the two first sub-pixels and the one third sub-pixel, the second operating voltage transmission line is configured to transmit a second operating voltage, which is different from the first operating voltage, to the one second sub-pixel.

Abstract: A semiconductor package includes a die with an embedded circuit. The semiconductor package includes an interconnect with a die pad, and the die is on the die pad. The interconnect includes leads. The semiconductor package includes a mold compound encapsulating a portion of the interconnect, and the leads extend away from the mold compound. The semiconductor package includes an immersion tin layer on a tip of the leads. The immersion tin layer overlays copper of the leads.

Abstract: Provided is pharmaceutical use of a nucleoside compound, specifically use of compound represented by formula (I) or a pharmaceutically acceptable salt thereof in the preparation of a drug for preventing or treating an infectious disease of orthopoxvirus. The compound represented by formula (I) has a significant inhibitory effect on a vaccinia virus, a monkeypox virus, a cowpox virus, and a smallpox virus.

Abstract: A rod-spring structured clamping and loosening device for a downhole belt replacement apparatus includes an upper and a lower cylinder fixed seat. The upper and the lower cylinder fixed seat are respectively connected to a first and a second set of pull rods, and each set of the pull rods pass through a first transition plate, a second transition plate, and a third transition plate. A first chuck is mounted on a side of the first transition plate facing the upper cylinder fixed seat, a second chuck is mounted on a side of the third transition plate facing the lower cylinder fixed seat, and the first and the second set of the pull rods are fixed at the first and the second chuck. A disc spring is mounted between the first and the second transition plate, and a jack is mounted between the second and the third transition plate.

Abstract: A preparation delivery assembly includes: a first substrate, a second substrate, and at least two needles of different lengths. Two side walls are provided between the first and second substrates to define a first chamber. At least one first channel that is in communication with the first chamber is provided in the second substrate in a direction perpendicular to the second substrate. And the needles are arranged on a surface of the second substrate, and each needle is in communication with the first chamber to deliver the preparation. A third channel is provided in the first substrate in a direction perpendicular to the first substrate, and one end of the third channel is in communication with the first chamber so as to guide the preparation introduced from the other end of the third channel into the first chamber.

Abstract: A side-by-side seamlessly fitting group of slide plates includes a frame, a support rod is horizontally arranged on a top side of the frame, a plurality of support plates are rotatably connected to an outer side of the support rod, a permanent magnet linear synchronous motor is arranged on a top surface of each support plate, a linear slide rail is arranged on a top surface of the permanent magnet linear synchronous motor, a slider is slidably connected to an outer side of the linear slide rail, a mounting plate and a slide plate are arranged on a top surface of the slider in sequence, sides of two adjacent ones of the slide plates seamlessly fit to each other, and a bent end of the mounting plate extends to a side surface of the permanent magnet linear synchronous motor and is threadedly connected to a connecting plate.

Abstract: Provided are a compound of Formula (I) and a pharmaceutical composition thereof, as well as a method for using the compounds of Formula (I) to prevent and/or treat immune-related disorders.

Abstract: A display substrate, a preparation method thereof, and a display apparatus, the display substrate includes a base substrate; a drive circuit layer provided on the base substrate; a light-emitting structure layer provided on a side of the drive circuit layer away from the base substrate, the light-emitting structure layer includes a pixel defining layer and an organic light-emitting layer, the pixel defining layer defines multiple sub-pixel regions and includes a first opening at least partially exposing the drive circuit layer, the organic light-emitting layer is located in the sub-pixel region and is overlapped with the first opening of the pixel defining layer; and a color film structure layer provided on a side of the light-emitting structure layer away from the base substrate, the color film structure layer includes a color film and a black matrix, the black matrix includes a second opening at least partially exposing the first opening.

Abstract: The present disclosure discloses a composition for improving eyesight, and relates to the technical field of food. The composition comprises Plukenetia volubilis oil, citri reticulatae pericarpium oil, and lutein ester. The composition can be prepared into a powder, a tablet, a capsule, a granule, an oral preparation, and a dripping pill. The composition can effectively relieve asthenopia, prevent impaired vision, and improve eyesight, and has a good market prospect.

Abstract: This application relates to a link width adjustment method and apparatus. The method includes: sending, to a second-end apparatus through a first channel, a first packet indicating to perform link width switching; receiving a second packet that is returned by the second-end apparatus and that indicates that the link width switching is agreed on; sending, to the second-end apparatus through a second channel, a first bit stream to test the second channel for data communication; and sending a data stream to the second-end apparatus through the first channel and the second channel.

Abstract: Provided are a display substrate and a display device. The display substrate includes: a base substrate and a plurality of sub-pixels on the base substrate; each sub-pixel includes: a pixel circuit including a storage capacitor including a first electrode plate and a second electrode plate; a light-emitting element; and a pixel definition layer. The sub-pixels include a plurality of openings, orthographic projections of the opening and the second electrode plate on the base substrate are overlapped; the second electrode plate includes a first edge and a second edge extending in the first direction; the opening includes a first edge and a second edge extending in the first direction; the first edge of the second electrode plate is closer to the first edge of the opening; the second edge of the second electrode plates is closer to the second edge of the opening.

Abstract: Devices, systems and methods for blood glucose monitoring. The device includes a light emitter, configured to emit light signals; a light receiver, configured to receive the reflected light signal; a controller, configured to operatively connect with the light emitter and the light receiver; and an enclosure. The light signal comprises a first light signal having a first wavelength of about 940 nm, a second light signal having a second wavelength of about 1350 nm, and/or a third light signal having a third wavelength of about 1500 nm, wherein the controller comprises an operating module, and further comprises or operatively connects with a data processing system comprising a machine learning module that analyzes the data signal to generate an output data. The devices, systems and methods are non-invasive and monitor blood glucose levels in real time with high accuracy.