Patents by Inventor Paola Daverio

Paola Daverio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of diaminophenothiazinium compounds having a high degree of purity
    Patent number: 10723710
    Abstract: A process for the preparation of diaminophenothiazinium compounds is described, which allows achieving quickly and effectively a high degree of purity of the same.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: July 28, 2020
    Assignee: ICROM S.P.A.
    Inventors: Matteo Colombo, Paola Daverio, Stella Borrelli
  • PROCESS FOR THE PREPARATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS HAVING A HIGH DEGREE OF PURITY
    Publication number: 20190185440
    Abstract: A process for the preparation of diaminophenothiazinium compounds is described, which allows achieving quickly and effectively a high degree of purity of the same.
    Type: Application
    Filed: May 16, 2017
    Publication date: June 20, 2019
    Inventors: Matteo COLOMBO, Paola DAVERIO, Stella BORRELLI
  • Polymorphs of atomoxetine hydrochloride
    Publication number: 20100076225
    Abstract: The present invention provides novel crystalline polymorph forms of atomoxetine hydrochloride denominated Forms B and C and methods for their preparation, as well as methods for the preparation of Form A. The present invention provides pharmaceutical compositions that comprise atomoxetine hydrochloride Form B, Form C, or mixtures thereof that can be used to treat attention deficit/hyperactivity disorder.
    Type: Application
    Filed: December 3, 2009
    Publication date: March 25, 2010
    Inventors: Judith Aronhime, Stefano Bianchi, Eugenio Castelli, Paola Daverio, Silvia Mantovani, Adrienne Kovacsne-Mezei
  • Process for Preparing Clopidogrel Bisulphate
    Publication number: 20090247569
    Abstract: Provided are processes for the preparation of clopidogrel bisulphate Form I.
    Type: Application
    Filed: August 3, 2007
    Publication date: October 1, 2009
    Inventors: Claude Singer, Basem Masarwa, Greta Sterimbaum, Paola Daverio, Eran Turgeman
  • PROCESSES FOR PREPARING DARIFENACIN HYDROBROMIDE
    Publication number: 20090156831
    Abstract: The invention encompasses processes for the preparation of darifenacin hydrobromide.
    Type: Application
    Filed: February 19, 2009
    Publication date: June 18, 2009
    Inventors: Valeriano MERLI, Augusto CANAVESI, Paola DAVERIO
  • Process for the preparation of atomoxetine hydrochloride
    Patent number: 7507861
    Abstract: The present invention provides improved processes for the preparation of atomoxetine hydrochloride under reaction conditions that improve reaction yields and facilitate commercial synthesis. In particular, the invention is directed to the synthesis of atomoxetine HCl by adding HCl to a mixture of (R)-(?)-tomoxetine (S)-(+)-mandelate with an organic solvent, with or without a base and water.
    Type: Grant
    Filed: June 28, 2005
    Date of Patent: March 24, 2009
    Assignee: Teva Pharmaceutical Fine Chemicals, S.r.l.
    Inventors: Eugenio Castelli, Giuseppe Lo Monaco, Silvia Mantovani, Paola Daverio, Paolo Riva, Alessandra Vailati, Stefano Bianchi
  • Levalbuterol hydrochloride polymorph B
    Patent number: 7488758
    Abstract: The invention is directed to levalbuterol HCl Form B and methods of making the same.
    Type: Grant
    Filed: May 20, 2005
    Date of Patent: February 10, 2009
    Assignee: Teva Pharmaceutical Fine Chemicals, S.r.l.
    Inventors: Valeriano Merli, Silvia Mantovani, Stefano Bianchi, Paola Daverio, Angelo Spreafico, Judith Aronhime, Adrienne Kovacsne-Mezei
  • Enantiomerically pure (R)-albuterol dibenzoyltartrate and protected analogs thereof
    Patent number: 7482489
    Abstract: Provided are processes for the preparation of (R)-SLB.D-DBTA salt and levalbuterol hydrochloride. Also provided are levalbuterol hydrochloride degradation products and processes for preparing them. Pharmaceutical compositions comprising at least one levalbuterol hydrochloride of the invention and at least one pharmaceutically-acceptable excipient are also provided.
    Type: Grant
    Filed: May 20, 2005
    Date of Patent: January 27, 2009
    Assignee: Teva Pharmaceutical Fine Chemicals S.r.l.
    Inventors: Valeriano Merli, Silvia Mantovani, Stefano Bianchi, Paola Daverio
  • Polymorphs of atomoxetine hydrochloride
    Patent number: 7473804
    Abstract: The present invention provides novel crystalline polymorph forms of atomoxetine hydrochloride denominated Forms B and C and methods for their preparation, as well as methods for the preparation of Form A. The present invention provides pharmaceutical compositions that comprise atomoxetine hydrochloride Form B, Form C, or mixtures thereof that can be used to treat attention deficit/hyperactivity disorder.
    Type: Grant
    Filed: July 21, 2005
    Date of Patent: January 6, 2009
    Assignee: Teva Pharmaceutical Fine Chemicals s.r.l.
    Inventors: Judith Aronhime, Stefano Bianchi, Eugenio Castelli, Paola Daverio, Silvia Mantovani, Adrienne Kovacsne-Mezei
  • Polymorphs of atomoxetine hydrochloride
    Publication number: 20080312471
    Abstract: The present invention provides novel crystalline polymorph forms of atomoxetine hydrochloride denominated Forms B and C and methods for their preparation, as well as methods for the preparation of Form A. The present invention provides pharmaceutical compositions that comprise atomoxetine hydrochloride Form B, Form C, or mixtures thereof that can be used to treat attention deficit/hyperactivity disorder.
    Type: Application
    Filed: August 11, 2008
    Publication date: December 18, 2008
    Inventors: Judith Aronhime, Stefano Bianchi, Eugenio Castelli, Paola Daverio, Silvia Mantovani, Adrienne Kovacsne-Mezei
  • Levalbuterol hydrochloride Polymorph A
    Patent number: 7465831
    Abstract: The invention is directed to processes for making levalbuterol HCl Polymorph A from by suspending or forming a first slurry of (R)-SLB(D)-DBTA in at least a first organic solvent, adding HCl to the suspension or slurry of the solid (R)-SLB.D-DBTA until the (R)-SLB.D-DBTA forms levalbuterol HCl Polymorph A, and isolating the levalbuterol HCl Polymorph A.
    Type: Grant
    Filed: July 11, 2007
    Date of Patent: December 16, 2008
    Assignee: Teva Pharmaceutical Fine Chemicals s.r.l.
    Inventors: Valeriano Merli, Silvia Mantovani, Stefano Bianchi, Paola Daverio, Angelo Spreafico, Judith Aronhime, Adrienne Kovacsne-Mezei
  • Polymorphs of memantine hydrochloride
    Patent number: 7462743
    Abstract: A crystalline Form II of memantine hydrochloride, pharmaceutical compositions containing crystalline Form II, and methods of preparing crystalline Forms I and II of memantine hydrochloride are provided.
    Type: Grant
    Filed: January 11, 2006
    Date of Patent: December 9, 2008
    Assignee: Teva Pharmaceutical Fine Chemicals S.r.l.
    Inventors: Valeriano Merli, Paola Daverio, Adrienne Kovacsne-Mezei, Judith Aronhime
  • Processes for preparing darifenacin hydrobromide
    Publication number: 20080269505
    Abstract: The invention encompasses processes for the preparation of darifenacin hydrobromide.
    Type: Application
    Filed: July 1, 2008
    Publication date: October 30, 2008
    Inventors: Valeriano Merli, Augusto Canavesi, Paola Daverio
  • Pure darifenacin hydrobromide substantially free of oxidized darifenacin and salts thereof and processes for the preparation thereof
    Publication number: 20080269504
    Abstract: Provided are darifenacin hydrobromide free of oxidized darifenacin, and processes for the preparation thereof.
    Type: Application
    Filed: July 1, 2008
    Publication date: October 30, 2008
    Inventors: Valeriano Merli, Augusto Canavesi, Paola Daverio, Alessandra Vailati
  • Processes for preparing darifenacin hydrobromide
    Publication number: 20080269503
    Abstract: The invention encompasses processes for the preparation of darifenacin hydrobromide.
    Type: Application
    Filed: July 1, 2008
    Publication date: October 30, 2008
    Inventors: Valeriano Merli, Augusto Canavesi, Paola Daverio
  • Processes for preparing darifenacin hydrobromide
    Patent number: 7442806
    Abstract: The invention encompasses processes for the preparation of darifenacin hydrobromide.
    Type: Grant
    Filed: December 27, 2006
    Date of Patent: October 28, 2008
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Valeriano Merli, Augusto Canavesi, Paola Daverio
  • Enantiomerically pure atomoxetine and tomoxetine mandelate
    Patent number: 7439398
    Abstract: The present invention provides enantiomerically pure (R)-(?)-tomoxetine (S)-(+)-mandelate and atomoxetine HCl. The present invention further provides enantiomerically pure (R)-(?)-tomoxetine (S)-(+)-mandelate prepared from racemic tomoxetine. The present invention also provides enantiomerically pure atomoxetine HCl prepared from (R)-(?)-tomoxetine (S)-(+)-mandelate.
    Type: Grant
    Filed: June 28, 2005
    Date of Patent: October 21, 2008
    Assignee: Teva Pharmaceutical Fine Chemicals S.R.L.
    Inventors: Eugenio Castelli, Paola Daverio, Silvia Mantovani
  • Processes for the preparation of atomoxetine hydrochloride
    Patent number: 7439399
    Abstract: The present invention provides improved processes for the preparation of atomoxetine hydrochloride under reaction conditions that improve reaction yields and facilitate commercial synthesis. In particular, the invention is directed to the synthesis of atomoxetine HCl by adding HCl to a mixture of (R)-(?)-tomoxetine (S)-(+)-mandelate with an organic solvent, with or without a base and water. In preferred embodiments, the atomoxetine hydrochloride produced is Form A.
    Type: Grant
    Filed: September 7, 2005
    Date of Patent: October 21, 2008
    Assignee: Teva Pharmaceutical Fine Chemicals
    Inventors: Judith Aronhime, Stefano Bianchi, Eugenio Castelli, Paola Daverio, Silvia Mantovani, Adrienne Kovacsne-Mezei
  • Processes for preparing darifenacin hydrobromide
    Publication number: 20080221338
    Abstract: The invention encompasses processes for the preparation of darifenacin hydrobromide.
    Type: Application
    Filed: May 6, 2008
    Publication date: September 11, 2008
    Inventors: Valeriano Merli, Augusto Canavesi, Paola Daverio
  • Pure darifenacin hydrobromide substantially free of oxidized darifenacin and salts thereof and processes for the preparation thereof
    Publication number: 20080216562
    Abstract: Provided are darifenacin hydrobromide free of oxidized darifenacin, and processes for the preparation thereof.
    Type: Application
    Filed: May 6, 2008
    Publication date: September 11, 2008
    Inventors: Valeriano Merli, Augusto Canavesi, Paola Daverio, Alessandra Vailati