Patents by Inventor Paola Maffei

Paola Maffei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140235662
    Abstract: The present invention describes rifaximin powder and to a process for preparing the same. The invention relates also to a pharmaceutical composition in solid form comprising said rifaximin, pharmaceutically acceptable excipients and optionally other ingredients. The compositions according to the invention are suitable for oral administration and are characterized by producing a controlled release of rifaximin, whereby a long-lasting effect is obtained in a patient.
    Type: Application
    Filed: April 24, 2014
    Publication date: August 21, 2014
    Applicant: ALFA WASSERMANN S.P.A.
    Inventors: Giuseppe Claudio VISCOMI, Paola MAFFEI, Vittoria LAURO, Miriam BARBANTI, Donatella CONFORTINI, Dario BRAGA
  • Patent number: 8748449
    Abstract: Polyols stabilize polymorphous form of rifaximin, in particular the ? form. When polyols having at least two hydroxy groups are added to rifaximin powder, polymorph ? is stable and remains stable in time independently from the environment humidity. In this invention a method to prepare formulations constituted by pure and stable polymorphous forms able to give a pharmaceutical product is described.
    Type: Grant
    Filed: July 9, 2012
    Date of Patent: June 10, 2014
    Assignee: Alfa Wassermann S.p.A.
    Inventors: Paola Maffei, Milena Bachetti, Giuseppe Bottoni, Giuseppe Claudio Viscomi
  • Patent number: 8748447
    Abstract: The present invention describes rifaximin powder and to a process for preparing the same. The invention relates also to a pharmaceutical composition in solid form comprising said rifaximin, pharmaceutically acceptable excipients and optionally other ingredients. The compositions according to the invention are suitable for oral administration and are characterized by producing a controlled release of rifaximin, whereby a long-lasting effect is obtained in a patient.
    Type: Grant
    Filed: March 4, 2011
    Date of Patent: June 10, 2014
    Assignee: Alfa Wassermann S.p.A.
    Inventors: Giuseppe Claudio Viscomi, Paola Maffei, Vittoria Lauro, Miriam Barbanti, Donatella Confortini, Dario Braga
  • Publication number: 20130072676
    Abstract: Polyols stabilize polymorphous form of rifaximin, in particular the ? form. When polyols having at least two hydroxy groups are added to rifaximin powder, polymorph ? is stable and remains stable in time independently from the environment humidity. In this invention a method to prepare formulations constituted by pure and stable polymorphous forms able to give a pharmaceutical product is described.
    Type: Application
    Filed: July 9, 2012
    Publication date: March 21, 2013
    Applicant: ALFA WASSERMANN, S.P.A.
    Inventors: Paola MAFFEI, Milena BACHETTI, Giuseppe BOTTONI, Giuseppe Claudio VISCOMI
  • Publication number: 20130028971
    Abstract: The invention relates generally to pharmaceutical compositions comprising rifaximin effective at treating vaginal infections, and in particular bacterial vaginosis. The pharmaceutical compositions comprising rifaximin granules are characterized in that they release rifaximin in the vagina in a controlled way. The present invention also relates to processes for preparation of the rifaximin pharmaceutical compositions and their use in the treatment of vaginal infections. Effective dosages and courses of treatment useful and effective at recovering from the disease and preventing any possible relapse are also provided.
    Type: Application
    Filed: July 26, 2012
    Publication date: January 31, 2013
    Applicant: ALFA WASSERMANN S.P.A.
    Inventors: Giuseppe Claudio VISCOMI, Paola MAFFEI, Vittoria LAURO, Fiorella CALANNI, Beatrice VITALI, Federica CRUCIANI
  • Publication number: 20130004576
    Abstract: The present invention describes rifaximin powder and to a process for preparing the same. The invention relates also to a pharmaceutical composition in solid form comprising said rifaximin, pharmaceutically acceptable excipients and optionally other ingredients. The compositions according to the invention are suitable for oral administration and are characterized by producing a controlled release of rifaximin, whereby a long-lasting effect is obtained in a patient.
    Type: Application
    Filed: March 4, 2011
    Publication date: January 3, 2013
    Applicant: ALFA WASSERMANN S.P.A.
    Inventors: Giuseppe Claudio Viscomi, Paola Maffei, Vittoria Lauro, Miriam Barbanti, Donatella Confortini, Dario Braga
  • Publication number: 20120245192
    Abstract: Disclosed herein are methods of treating a patient having an intestinal disorder, the methods comprising: administering to a patient in need thereof a pharmaceutical composition comprising a hydrate or solvate form of rifaximin in polymorphic form ?, alone or in a mixture with other crystalline, hydrate, solvate or amorphous forms of rifaximin, in gastroresistant microgranules, wherein the rifaximin is administered at a dose of at least 800 mg per day for a period of at least 7 days.
    Type: Application
    Filed: September 21, 2011
    Publication date: September 27, 2012
    Applicant: ALFA WASSERMANN, S.P.A.
    Inventors: Giuseppe Claudio Viscomi, Paola Maffei, Giuseppe Bottoni, Maria Grimaldi
  • Publication number: 20120238630
    Abstract: The present invention describes liquid compositions comprising pharmaceutically active principles, like scarcely water-soluble, nonsteroidal anti-inflammatory drugs, in particular, but not exclusively, flurbiprofen (FP), processes for their manufacture and their therapeutic use. The liquid compositions comprising FP in association with natural polymers, like xyloglucans (XG), and pharmaceutically acceptable excipients like glycerol, are suitable to be used for pharmaceutical uses and are characterized by good tolerability, therapeutic efficacy, stability and palatability.
    Type: Application
    Filed: November 17, 2010
    Publication date: September 20, 2012
    Applicant: Alfa Wassermann S.P.A.
    Inventors: Giuseppe Claudio Viscomi, Giuseppe Bottoni, Paola Maffei, Annalisa Sforzini, Jackie Leeder, Vittoria Lauro
  • Patent number: 8217054
    Abstract: Polyols stabilize polymorphous form of rifaximin, in particular the ? form. When polyols having at least two hydroxy groups are added to rifaximin powder, polymorph ? is stable and remains stable in time independently from the environment humidity. In this invention a method to prepare formulations constituted by pure and stable polymorphous forms able to give a pharmaceutical product is described.
    Type: Grant
    Filed: July 31, 2007
    Date of Patent: July 10, 2012
    Assignee: Alfa Wassermann, S.p.A.
    Inventors: Paola Maffei, Milena Bachetti, Giuseppe Bottoni, Giuseppe Claudio Viscomi
  • Publication number: 20120088726
    Abstract: Object of the invention are mucoadhesive and controlled release formulations consisting of aqueous solutions containing 0.05% to 5% by weight of a natural purified polymer having xyloglucan structure and 10% to 70% by weight of glycerol. These formulations are suitable for the application on human mucous membranes, such as nasal, oral and vaginal mucous membranes, as moisturizing and softening agents or as pharmaceutical release system. Further objects of the invention are pharmaceutical formulations and medical devices suitable for the application to human mucous membranes, containing the mucoadhesive and controlled release formulations together with active ingredients and excipients.
    Type: Application
    Filed: October 19, 2011
    Publication date: April 12, 2012
    Applicant: ALFA WASSERMANN, S.P.A.
    Inventors: Giuseppe Bottoni, Paola Maffei, Annalisa Sforzini, Mascia Federici, Carla Caramella, Silvia Rossi, Giuseppe Claudio Viscomi
  • Publication number: 20100010028
    Abstract: Polyols stabilize polymorphous form of rifaximin, in particular the ? form. When polyols having at least two hydroxy groups are added to rifaximin powder, polymorph ? is stable and remains stable in time independently from the environment humidity. In this invention a method to prepare formulations constituted by pure and stable polymorphous forms able to give a pharmaceutical product is described.
    Type: Application
    Filed: July 31, 2007
    Publication date: January 14, 2010
    Applicant: Alfa Wassermann, S.P.A.
    Inventors: Paola Maffei, Milena Bachetti, Gluseppe Bottoni, Giuseppe Claudio Viscomi
  • Publication number: 20090081133
    Abstract: Mucoadhesive and controlled release formulations consisting of aqueous solutions containing 0.05% to 5% by weight of a natural purified polymer having xyloglucan structure and 10% to 70% by weight of glycerol. These formulations are suitable for the application on human mucous membranes, such as nasal, oral and vaginal mucous membranes, as moisturizing and softening agents or as pharmaceutical release system. Further objects of the invention are pharmaceutical formulations and medical devices suitable for the application to human mucous membranes, containing the mucoadhesive and controlled release formulations together with active ingredients and excipients.
    Type: Application
    Filed: June 1, 2006
    Publication date: March 26, 2009
    Inventors: Giuseppe Bottoni, Paola Maffei, Annalisa Sforzini, Mascia Federici, Carla Caramella, Silvia Rossi, Giuseppe Claudio Viscomi