Abstract: The present invention relates to novel pharmaceutical combinations and compositions comprising sucralfate and magnesium alginate, a process for their preparation and the use of said compositions in therapy, in particular for the treatment and/or prevention of disorders of the upper gastro-intestinal tract.

Abstract: This invention relates to a powder composition for inhalation use comprising a plurality of microparticles comprising at least one water-soluble pharmaceutically acceptable carrier embedding at least one nanoparticle of calcium phosphate for the delivery of therapeutic/diagnostic compounds.

Abstract: The present invention relates to novel pharmaceutical combinations and compositions comprising sucralfate and magnesium alginate, a process for their preparation and the use of said compositions in therapy, in particular for the treatment and/or prevention of disorders of the upper gastro-intestinal tract.

Abstract: A geopolymeric ink formulation for direct 3D printing containing a geopolymeric formulation whose components are present in such proportions as to be subjected to a geopolymerization reaction and to provide, at the end of the reaction, a solid geopolymer and wherein the formulation, before and during at least a part of the geopolymerization reaction, wherein three-dimensional chemical bonds have not yet been formed, forms a reversible-gel, non-Newtonian, viscoelastic fluid. The formulation is extruded through a 3D printing tool equipped with nozzle into strands according to a geometry such as to create a three-dimensional structure on one or more layers. The extrusion preferably takes place within a hydrophobic liquid, such as oil.

Abstract: An inhalable microparticles having cysteamine hyaluronate salt is provided. Also a preparation method and a pharmaceutical composition thereof are provided.

Abstract: Method for producing a friction material, including the following steps in sequence: mixing an aluminosilicate source with an alkaline silicate solution to form a geopolymer, adding a friction mix to the geopolymer solution of the previous step to obtain a slurry, casting the slurry in a mold at temperature between room temperature and 120° C. and for between 5 min and 2 h and demolding to obtain a pad, attaching a backplate to the pad, curing for a time between X and Y hours at a temperature of between X and Y. The friction material obtained with the method is for the manufacture of friction layers/blocks for friction elements such as braking elements, including vehicle brake pads or blocks, and/or friction discs.

Abstract: A method for producing a solid body of glass is described. The method comprises providing a polymerisable composition, curing the polymerisable composition to obtain a cured body, subjecting the cured body to thermal debinding to substantially remove the organic components in the cured body, and subjecting the cured body to sintering to obtain a solid body of silica glass. The polymerisable composition one or more at least partially organic polymerisable compound(s) which form a liquid composition at operating temperature and a solid source of silica as colloidal silica particles or silica glass micro-/nanoparticles dispersed in the liquid composition. The one or more at least partially organic polymerisable compounds comprises at least one organosilicon compound as a second source of silica that is liquid or solubilisable in the liquid composition at operating temperature to thereby increase the silica loading of the cured body prior to sintering.

Abstract: Materials that seamlessly transition from opaque to transparent or translucent, such as advanced geopolymer-based ceramics to glass structures, which can be directly and seamlessly bonded without the use of an intermediate adhesive or use of a frame are disclosed. That is, a GP-based ceramic to glass structure can be bonded directly and seamlessly and without any mechanical joints, connective tissue or adhesives such as caulking or epoxy. Such ceramic to glass materials can be prepared by sintering an engineered geopolymer with glass to form the geopolymer-based advanced ceramic-glass structure in which the interface is visually abruptly or in which the material is a graded composition with a controlled transition from one material to the other.

Abstract: A geopolymeric ink formulation for direct 3D printing containing a geopolymeric formulation whose components are present in such proportions as to be subjected to a geopolymerization reaction and to provide, at the end of the reaction, a solid geopolymer and wherein the formulation, before and during at least a part of the geopolymerization reaction, wherein three-dimensional chemical bonds have not yet been formed, forms a reversible-gel, non-Newtonian, viscoelastic fluid. The formulation is extruded through a 3D printing tool equipped with nozzle into strands according to a geometry such as to create a three-dimensional structure on one or more layers. The extrusion preferably takes place within a hydrophobic liquid, such as oil.

Abstract: Method for creating a brake pad with a block of friction material, in which sodium hydroxide and sodium silicate are dissolved in water, the aqueous solution of sodium hydroxide and sodium silicate is mixed with commercial metakaolin until a wet paste is obtained, the wet paste is formed and dried until a dried geopolymeric aggregate is obtained, the aggregate is ground to a powder, the dried ground aggregate is used as an exclusive or almost-exclusive inorganic geopolymeric binder in a friction material compound and the raw compound is hot-molded under a pressure greater than a water saturation pressure at the molding temperature.

Abstract: A geopolymeric ink formulation for direct 3D printing containing a geopolymeric formulation whose components are present in such proportions as to be subjected to a geopolymerization reaction and to provide, at the end of the reaction, a solid geopolymer and wherein the formulation, before and during at least a part of the geopolymerization reaction, wherein three-dimensional chemical bonds have not yet been formed, forms a reversible-gel, non-Newtonian, viscoelastic fluid. The formulation is extruded through a 3D printing tool equipped with nozzle into strands according to a geometry such as to create a three-dimensional structure on one or more layers. The extrusion preferably takes place within a hydrophobic liquid, such as oil.

Abstract: An inhalable microparticles having cysteamine hyaluronate salt is provided. Also a preparation method and a pharmaceutical composition thereof are provided.

Abstract: Crystalline microparticles consisting of a phenylalkylamino beta2-adrenergic agonist coated with a C12-C20 fatty acid are useful for the preparation of pharmaceutical aerosol formulations in form of suspension in a liquefied propellant gas or powder formulations.

Abstract: An asbestos-free friction material having at least one of the group consisting of inorganic, organic and metallic fibers, at least one binder, at least one friction modifier or lubricant and at least a filler or abrasive, wherein the binder is almost completely and exclusively inorganic and is constituted almost exclusively by a hydrated geopolymer or a blend of hydrated geopolymers.

Abstract: Oral cysteamine formulation consisting of dry layered lipid matrix microparticles useful for treating cystinosis and neurodegenerative disorders are described.

Abstract: A geopolymeric ink formulation for direct 3D printing containing a geopolymeric formulation whose components are present in such proportions as to be subjected to a geopolymerization reaction and to provide, at the end of the reaction, a solid geopolymer and wherein the formulation, before and during at least a part of the geopolymerization reaction, wherein three-dimensional chemical bonds have not yet been formed, forms a reversible-gel, non-Newtonian, viscoelastic fluid. The formulation is extruded through a 3D printing tool equipped with nozzle into strands according to a geometry such as to create a three-dimensional structure on one or more layers. The extrusion preferably takes place within a hydrophobic liquid, such as oil.

Abstract: Crystalline microparticles consisting of a phenylalkylamino beta2-adrenergic agonist coated with a C12-C20 fatty acid are useful for the preparation of pharmaceutical aerosol formulations in form of suspension in a liquefied propellant gas or powder formulations.

Abstract: A display structure particularly for the display and sale of cosmetic products and products in general, in stores such as beauty stores and/or multi- or mono-brand stores, comprises at least one pair of guide elements (2) assembled in a cabinet and adapted to support one or more modular plate display elements (3) that are also directly interchangeable by store personnel.

Abstract: The invention provides a porous glass ceramic composition manufactured using conventional raw materials and one or more waste materials, wherein the waste materials are capable of producing glass forming oxides, glass modifying oxides and pore forming oxides. The waste materials are selected from a group that includes cullet, pozzolanic waste and fly ash. The invention also provides a method for manufacturing the porous glass ceramic composition.

Abstract: The present invention relates to the interaction between JMJD6 protein and collagen and to the possibility of inhibiting this interaction for the prevention and treatment of fibrosis and of tumor metastases. The invention further relates to a compound that is able to block the interaction between collagen and JMJD6 protein, in particular the invention relates to a new monoclonal antibody that recognizes JMJD6 and is able to block this interaction.