Abstract: An ESD protection network protects a CMOS circuit structure integrated in a semiconductor substrate. The circuit structure includes discrete circuit blocks formed in respective substrate portions which are electrically isolated from one another and independently powered from at least one primary voltage supply having a respective primary ground, and from at least one secondary voltage supply having a respective secondary ground. This network includes a first ESD protection element for an input stage of the circuit structure; a second ESD protection element for an output stage of the circuit structure, the first and second protection elements having an input/output pad of the integrated circuit structure in common; a first ESD protection element between the primary supply and the primary ground; and a second ESD protection element between the secondary supply and the secondary ground.

Abstract: A method and a related circuit structure are described for improving the effectiveness of ESD protection in circuit structures realized in a semiconductor substrate overlaid with an epitaxial layer and including at least one ESD protection lateral bipolar transistor realized in the surface of the epitaxial layer. The method consists of forming under the transistor an isolating well that isolates the transistor from the substrate. Advantageously, the transistor can be fully isolated from the substrate by first and second N wells which extend from the surface of the epitaxial layer down to and in contact with the buried well.

Abstract: Process for the preparation of etodolac, comprising the following steps:a) reacting 7-ethyl-tryptophol of formula (II) with methyl 3-oxo-pentanoate of formula (III) thereby obtaining methyl 1,8-diethyl-1,3,4,9-tetrahydropyrano [3,4-bis] indole-1-acetate of formula (IV) in an apolar solvent;b) hydrolyzing the compound of formula (IV) to etodolac (I),wherein step (a) is carried out at a temperatures of between -20.degree. C. and +50.degree. C. in the presence of a concentrated mineral acid, the molar ratio of the inorganic acid to 7-ethyl-tryptophol being comprised between 0.5 and 5.

Abstract: A device for protection against electrostatic discharges on the terminals of a MOS integrated circuit and characterized in that it consists of a first and a second circuit branch coupled between the terminal to be protected and ground. The first circuit branch has two field transistors. The gate of the first field-effect transistor is connected to terminal to be protected, and the gate of the second field-effect transistor is connected to a first resistance of the second circuit branch. The second circuit branch has a third field-effect transistor with its gate terminal connected to ground and a second resistance inserted between the third transistor and the terminal to be protected.

Abstract: This invention concerns systems for the release of active principles which are capable of releasing active principle(s) into an aqueous medium at a controlled rate.More precisely, the invention concerns a monolithic system for the controlled release of active principles, consisting of:a) at least one swelling layer containing one or more active principles, in a matrix of swellable, hydrophilic polymers;b) at least one erodible and/or soluble layer comprising excipients and/or water soluble polymers, possibly containing one or more active principles, either the same or different from those present in the layer a), the said erodible and/or soluble layer being in contact with the swelling layer(s) a).

Abstract: Tablets with zero order controlled-rate of release of the active substances, consisting of a core of defined geometrical form containing the active substance, polymer substances which swell on contact with aqueous liquids and polymer substances with gelling properties, and a support applied to said core to partly cover its surface, the support consisting of polymer substances which are slowly soluble and/or slowly gellable in aqueous liquids, plasticizing substances, and possibly substances with an adjuvant function.

Abstract: Pharmaceutical compositions in the form of stable sucralfate suspensions free of suspending agents, wherein the sucralfate is present in the form of a gel having self-suspending properties and is suspended in an aqueous carbohydrate solution in a quantity of between 1 and 40% of sucralfate by weight.Said gel has a surface area exceeding 200 m.sup.2 /g and is prepared by dissolving powdered sucralfate in an HCl solution and then precipitating it with an NaOH solution added to a pH of between 4 and 4.5.

Abstract: Stable aqueous suspensions of zeolite 4A which can be easily pumped, containing from 0.5 to 65% of zeolite and from 0.05 to 6 g (per 100 g of zeolite) of a suspending agent, composed of mixtures of ethoxylated alkanols, said mixtures being obtained by ethoxylating: a) biodegradable branched alkanols, having from 10 to 18 carbon atoms and having a single branching in position 2, said mixtures containing at least 2 alkanols having a different number of C atoms; or b) mixtures containing 40-100% of branched alkanols as in a) and 60-0% of linear alkanols having from 10 to 18 C atoms.

Abstract: The use of sucralfate humid gel is described as vehicle for the application f drugs having topic activity (dermic and mucosal) and as basis for the formulation of beauty masks and other cosmetic preparations. Therapeutic and cosmetic formulations are described in the form of creams, ointments, aqueous dispersions comprising sucralfate humid gel.

Abstract: A process for the manufacture of aqueous solutions of anti-scaling agents, starting from maleic anhydride and vinyl acetate (and optionally from a third monomer), characterized in that:(A) the amount of vinyl acetate ranges from 40 to 70% by moles, with respect to the sum of all the comonomers, the amount of maleic anhydride ranges from 30 to 50% by moles, with respect to said sum, and the amount of termonomer ranges from 0 to 30% by moles, with respect to said sum, the molar ratio vinyl acetate/maleic anhydride being equal to or higher than 1;(B) maleic anhydride, vinyl acetate (and optionally said third monomer) are co-polymerized in an organic diluent having medium or low polarity;(C) the anhydrous suspension, obtained according to (B), is directly subjected to a reactive extraction with water.

Abstract: Transesterified copolymers of maleic anhydride, particularly useful in the field of detergency and anti-scaling agents, obtained from preformed copolymers of maleic anhydride with vinyl acetate, by at least partial transesterification of said preformed copolymers.

Abstract: A tablet for pharmaceutical use able to release active substances at successive times, comprising at least; a first layer containing a portion of the active substance with suitable excipients, a barrier layer of polymer material gellable and/or soluble in water and/or aqueous liquids, which is interposed between said first layer and a third layer containing the remaining portion of active substance with suitable excipients, said barrier layer and said third layer being housed in a casing consisting of polymer material impermeable and insoluble in water or soluble in an alkaline environment.That part of the active substance not inserted in the casing is immediately available for dissolving, whereas the part inserted in the casing is available only after dissolution or rupture of the barrier layer and/or after solubilization of the casing.

Abstract: A system for the controlled-rate release of active substances, consisting of:(a) a deposit-core comprising the active substance and having defined geometric form;(b) a support-platform applied to said deposit-core.Said deposit-core contains, mixed with the active substance, a polymeric material having a high degree of swelling on contact with water or aqueous liqids, a gellable polymeric material, said polymeric materials being replaceable by a single polymeric material having both swelling and gelling properties, and other adjuvants able to provide the mixture with suitable characteristics for its compression and for its intake of water.

Abstract: A delivery device for zero-order release of an active principle into a dissolution fluid includes a reservoir consisting of a solid matrix of a homogeneous mixture of a polymer material, at least a portion of the active principle and an additive soluble in the dissolution fluid with negative heat of solution, a coating on the solid matrix-type reservoir of a first, release rate-controlling insoluble membrane which modulates the active principle release according to the desired kinetics; and a second, protective membrane on the release rate-controlling membrane of a soluble polymer material.

Abstract: The present invention relates to a novel pharmacologically active salt derivative, constituted by 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxy-phenyl)-1-butanone 3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde-5-phosphate, to the process for the production thereof, and to the related pharmaceutical compositions.Said salt derivative is produced by reacting 3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde-5-phosphoric acid with 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-3-butanone in an organic solvent and subsequently crystallizing the reaction product.Said salt derivative carries out an important pharmacological activity as inhibitor of platelet aggregation with vasodilative action.

Abstract: A process for the production of a bleaching activator in granular form, in which an aqueous suspension of acetylated bleach activator is filtered to recover a filtration cake comprised of the acetylated bleach activator and having a moisture content of from 20 to 65% by weight; from 1 to 7 parts by weight of the filtration cake of step (a) is mixed and granulated with 1 part by weight of sodium tripolyphosphate in a granulator means to provide a granulated product; and the granulated product is dried to a residual moisture content of from 5 to 15% by weight to obtain the bleaching activator.

Abstract: The invention relates to laminated films and articles of manufacture based on such films and having improved resistance to heat treatment, wherein said films comprise a heat sealing layer of copolyamide obtained by random copolymerization of precursor monomers of at least two different polyamides. Said laminated films, or the articles of manufacture formed therefrom, such as bags or preformed containers, are useful for packaging applications, particularly in connection with food products.

Abstract: Polyformaldehyde is prepared by polymerizing anhydrous monomeric formaldehyde in an organic, liquid and inert diluent which is a non-solvent for polyformaldehyde, in the presence of a catalyst of the formula: ##STR1## wherein A.sup.(-) is a lactamate group: ##STR2## in which PM is a linear polymethylene chain with from 3 to 13 carbon atoms, possibly substituted with one or more alkyl, cycloalkyl, aryl or alkylaryl radicals, and wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 independently are an alkyl, cycloalkyl, aryl or alkylaryl radical.

Abstract: The terminal hydroxyl groups of an acetal polymer are esterified or etherified by reaction with an end-capping agent chosen from anhydrides of carboxylic acids, orthoesters and orthocarbonates, by forming an intimate mixture of polymer in powder form and liquid end-capping agent, the amount of said agent in the mixture being less than that which results in loss of the free-flowing characteristics of the powder, and reacting said mixture under stirring at 50.degree.-170.degree. C.

Abstract: Raw gaseous formaldehyde is purified by passing it through a first series of superimposed fluidized beds of solid adsorbent, maintained at 80.degree.-140.degree. C., while continuously circulating solid adsorbent from each bed to the underlying bed and discharging from the lowermost bed the spent adsorbent, delivering the latter to the uppermost bed of a second series of superimposed fluidized beds of solid adsorbent, passing through the latter a stream of inert gas to strip the adsorbed formaldehyde at 130.degree.-150.degree. C., while continuously circulating said spent adsorbent from each bed to the underlying bed and discharging from the lowermost bed the adsorbent thus treated, delivering the latter to the uppermost bed of a third series of fluidized beds of solid adsorbent, and passing through the latter a stream of inert gas to regenerate the adsorbent at 145.degree.-250.degree. C.