Patents by Inventor Parag V. Karmarkar

Parag V. Karmarkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8260399
    Abstract: A deflectable tip catheter that is safe and effective for use in a magnetic resonance imaging environment. The deflectable tip catheter is configured such that it includes a built-in antenna, such as a loopless antenna or a loop antenna. The built-in antenna permits the deflectable tip catheter to be actively tracked and/or visualized. Depending upon the specific configuration of the deflectable tip catheter, the catheter may be tracked and/or visualized as a single unit, it may be tracked and/or visualized separate and independent of other components or instruments associated with the catheter, such as pull wires, injection needles, surgical instruments, and the like. The catheters described herein include injection type catheters and/or guidance type catheters.
    Type: Grant
    Filed: April 9, 2010
    Date of Patent: September 4, 2012
    Assignee: Johns Hopkins University
    Inventors: Parag V. Karmarkar, Ergin Atalar
  • Publication number: 20120071953
    Abstract: Some embodiments are directed to MRI/RF compatible medical interventional devices. A plurality of spaced apart high impedance circuit segments are configured to have a high impedance at a high range of radiofrequencies and a low impedance at a low range of frequencies. The high impedance circuit segments may comprise co-wound coiled inductors and can reduce, block or inhibit RJ-transmission along the lead system (20) during exposure to RF associated with a high-Held magnet MRI systems, while permuting passage of low frequency physiologic signals, treatments and/or stimuli. The devices can include at least one electrode.
    Type: Application
    Filed: November 7, 2011
    Publication date: March 22, 2012
    Applicants: MRI Interventions, Inc., Boston Scientific Neuromodulation Corporation
    Inventors: Ergin Atalar, Justin Allen, Paul Bottomley, William Eldelstein, Parag V. Karmarkar
  • Patent number: 8108028
    Abstract: In vivio deep brain medical probe systems include: (a) an NMRI compatible cannula comprising a plurality of concentric axially extending tubes with a receiving bore; and (b) an elongate antenna member with a conductor and an insulating layer configured to slidably advance through cannula bore to define an MRI receive antenna.
    Type: Grant
    Filed: July 26, 2005
    Date of Patent: January 31, 2012
    Assignee: Surgi-Vision Inc.
    Inventor: Parag V. Karmarkar
  • Patent number: 8055351
    Abstract: Some embodiments are directed to MRI/RF compatible medical interventional devices. A plurality of spaced apart high impedance circuit segments are configured to have a high impedance at a high range of radiofrequencies and a low impedance at a low range of frequencies The high impedance circuit segments may comprise co-wound coiled inductors and can reduce, block or inhibit RJ-transmission along the lead system (20) during exposure to RF associated with a high-Held magnet MRI systems, while permuting passage of low frequency physiologic signals, treatments and/or stimuli The devices can include at least one electrode.
    Type: Grant
    Filed: October 20, 2006
    Date of Patent: November 8, 2011
    Assignees: Boston Scientific Neuromodulation Corporation, MRI Interventions, Inc.
    Inventors: Ergin Atalar, Justin Allen, Paul Bottomley, William Eldelstein, Parag V. Karmarkar
  • Publication number: 20100198049
    Abstract: A deflectable tip catheter that is safe and effective for use in a magnetic resonance imaging environment. The deflectable tip catheter is configured such that it includes a built-in antenna, such as a loopless antenna or a loop antenna. The built-in antenna permits the deflectable tip catheter to be actively tracked and/or visualized. Depending upon the specific configuration of the deflectable tip catheter, the catheter may be tracked and/or visualized as a single unit, it may be tracked and/or visualized separate and independent of other components or instruments associated with the catheter, such as pull wires, injection needles, surgical instruments, and the like. The catheters described herein include injection type catheters and/or guidance type catheters.
    Type: Application
    Filed: April 9, 2010
    Publication date: August 5, 2010
    Inventors: Parag V. Karmarkar, Ergin Atalar
  • Publication number: 20100168555
    Abstract: Disclosed is a guide catheter that includes one or more RF antennas to enhance the visibility of the guide catheter in MR imagery. One embodiment of the guide catheter includes a loop coil at the distal end of the guide catheter and a loopless antenna between the distal end and the proximal end. By combining a loop coil and a loopless antenna on the catheter, the shaft of the catheter may be visible in MR imagery while the distal end may appear in the MR imagery more brightly than the shaft.
    Type: Application
    Filed: December 24, 2009
    Publication date: July 1, 2010
    Inventors: Parag V. Karmarkar, Ergin Atalar, Robert J. Lederman, Amish N. Raval
  • Patent number: 7725161
    Abstract: A deflectable tip catheter that is safe and effective for use in a magnetic resonance imaging environment. The deflectable tip catheter is configured such that it includes a built-in antenna, such as a loopless antenna or a loop antenna. The built-in antenna permits the deflectable tip catheter to be actively tracked and/or visualized. Depending upon the specific configuration of the deflectable tip catheter, the catheter may be tracked and/or visualized as a single unit, it may be tracked and/or visualized separate and independent of other components or instruments associated with the catheter, such as pull wires, injection needles, surgical instruments, and the like. The catheters described herein include injection type catheters and/or guidance type catheters.
    Type: Grant
    Filed: February 3, 2004
    Date of Patent: May 25, 2010
    Assignee: John Hopkins University
    Inventors: Parag V. Karmarkar, Ergin Atalar
  • Publication number: 20100106171
    Abstract: Disclosed is a system for creating an anastomosis between the inferior vena cava (IVC) and the mesenteric portal vein. The system includes an anastomosis device and a catheter. The anastomosis device brings the IVC and the portal vein into apposition. The resulting anastomosis enables treatment for portal hypertension as well as provides repeated and easy access to the portal system for direct delivery of therapeutic agents to portal organs. The anastomosis device has a proximal flange part, a distal flange part, a flow lumen between them. The proximal and distal flange parts include a plurality of radial struts. A valve part is disposed on one or both of the proximal and distal flange parts. The anastomosis device is made of a memory shape material. The catheter contains a collapsed anastomosis device for insertion and has one or more RF antennas to make the catheter visible under MRI guidance.
    Type: Application
    Filed: May 5, 2006
    Publication date: April 29, 2010
    Applicant: JOHNS HOPKINS UNIVERSITY
    Inventors: Aravind Arepally, Parag V. Karmarkar, Qian Di, Ergin Atalar
  • Publication number: 20090216109
    Abstract: Implantable aneurysm-sac treatment devices include an implantable coil body configured and sized to reside in a sac of an aneurysm. The body has an inductance and capacitance. The capacitance is selected so that the coil resonates at a Larmor frequency of a predefined magnetic field strength.
    Type: Application
    Filed: October 4, 2006
    Publication date: August 27, 2009
    Inventors: Parag V. Karmarkar, Aravind Arepally
  • Publication number: 20090171421
    Abstract: Some embodiments are directed to MRI/RF compatible medical interventional devices.
    Type: Application
    Filed: October 20, 2006
    Publication date: July 2, 2009
    Inventors: Ergin Atalar, Justin Allen, Paul Bottomley, William Eldelstein, Parag V. Karmarkar
  • Publication number: 20090118610
    Abstract: MRI compatible localization and/or guidance systems for facilitating placement of an interventional therapy and/or device in vivo include: (a) a mount adapted for fixation to a patient; (b) a targeting cannula with a lumen configured to attach to the mount so as to be able to controllably translate in at least three dimensions; and (c) an elongate probe configured to snugly slidably advance and retract in the targeting cannula lumen, the elongate probe comprising at least one of a stimulation or recording electrode. In operation, the targeting cannula can be aligned with a first trajectory and positionally adjusted to provide a desired internal access path to a target location with a corresponding trajectory for the elongate probe. Automated systems for determining an MR scan plane associated with a trajectory and for determining mount adjustments are also described.
    Type: Application
    Filed: November 29, 2006
    Publication date: May 7, 2009
    Inventors: Parag V. Karmarkar, Kimble Jenkins
  • Publication number: 20080262584
    Abstract: MRI/RF compatible leads include at least one conductor, a respective conductor having at least one segment with a multi-layer stacked coil configuration. The lead can be configured so that the lead heats local tissue less than about 10 degrees Celsius (typically about 5 degrees Celsius or less) or does not heat local tissue when a patient is exposed to target RF frequencies at a peak input SAR of at least about 4 W/kg and/or a whole body average SAR of at least about 2 W/kg. Related leads and methods of fabricating leads are also described.
    Type: Application
    Filed: March 13, 2008
    Publication date: October 23, 2008
    Inventors: Paul A. Bottomley, Parag V. Karmarkar, Justin M. Allen, William A. Edelstein, Peter Piferi, Brian Gore, J. Michael Shifflette
  • Publication number: 20080243218
    Abstract: RF/MRI compatible leads include at least one conductor that turns back on itself at least twice in a lengthwise direction, and can turn back on itself at least twice at multiple locations along its length. The at least one electrical lead can be configured so that the lead heats local tissue less than about 10 degrees Celsius (typically about 5 degrees Celsius or less) or does not heat local tissue when a patient is exposed to target RF frequencies at a peak input SAR of at least about 4 W/kg and/or a whole body average SAR of at least about 2 W/kg. Related devices and methods of fabricating leads are also described.
    Type: Application
    Filed: March 13, 2008
    Publication date: October 2, 2008
    Inventors: Paul A. Bottomley, Parag V. Karmarkar, Justin M. Allen, William A. Edelstein
  • Publication number: 20080097193
    Abstract: In vivio deep brain medical probe systems include: (a) an NMRI compatible cannula comprising a plurality of concentric axially extending tubes with a receiving bore; and (b) an elongate antenna member with a conductor and an insulating layer configured to slidably advance through cannula bore to define an MRI receive antenna.
    Type: Application
    Filed: July 26, 2005
    Publication date: April 24, 2008
    Inventor: Parag V. Karmarkar
  • Publication number: 20040220470
    Abstract: A deflectable tip catheter that is safe and effective for use in a magnetic resonance imaging environment. The deflectable tip catheter is configured such that it includes a built-in antenna, such as a loopless antenna or a loop antenna. The built-in antenna permits the deflectable tip catheter to be actively tracked and/or visualized. Depending upon the specific configuration of the deflectable tip catheter, the catheter may be tracked and/or visualized as a single unit, it may be tracked and/or visualized separate and independent of other components or instruments associated with the catheter, such as pull wires, injection needles, surgical instruments, and the like. The catheters described herein include injection type catheters and/or guidance type catheters.
    Type: Application
    Filed: February 3, 2004
    Publication date: November 4, 2004
    Applicant: THE JOHN HOPKINS UNIVERSITY
    Inventors: Parag V. Karmarkar, Ergin Atalar