Patents by Inventor Patrice A. Lee

Patrice A. Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hemofiltration systems, methods and devices used to treat inflammatory mediator related disease
    Patent number: 6730266
    Abstract: A hemofiltration system for a mammal is provided with a hemofilter and an adsorbent device. The hemofilter removes ultrafiltrate from a blood stream extracted from the mammal to create a filtered blood stream and an ultrafiltrate stream. The adsorbent device has one or more adsorbent materials and is used to adsorb inflammatory mediators from the ultrafiltrate stream received from the hemofilter removing inflammatory mediators that cause inflammatory mediator related disease, sepsis, and SIRS/MODS/MOSF to create a post adsorption ultrafiltrate stream. The post adsorption ultrafiltrate stream is selectively combined with the filtered blood stream and together with the filtered blood stream is returned to the mammal.
    Type: Grant
    Filed: July 25, 2001
    Date of Patent: May 4, 2004
    Assignee: Immunocept, L.L.C.
    Inventors: James R. Matson, Patrice A. Lee
  • METHOD AND SYSTEM FOR COLLOID EXCHANGE THERAPY
    Publication number: 20040060866
    Abstract: The present invention relates to a method and system for using a hemofilter to treat IMRD, hepatic failure, exogenous intoxication and other conditions associated with toxins in a patient's blood. One treatment includes the use of a very large pore hemofilter to remove target complex molecules and/or target molecules from a patient's blood and to infuse a replacement fluid into the patient's blood to maintain a prescribed albumin concentration in the patient's blood.
    Type: Application
    Filed: May 15, 2001
    Publication date: April 1, 2004
    Applicant: Immunocept, L.L.C.
    Inventors: David Radunsky, James R. Matson, Patrice A. Lee
  • In vivo models for screening inhibitors of hepatitis B virus
    Publication number: 20030140362
    Abstract: The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of disease states related to hepatitis B virus (HBV) replication and gene expression. HBV animal models and methods of use are provided, including methods of screening for compounds and/or potential therapies directed against HBV.
    Type: Application
    Filed: October 24, 2002
    Publication date: July 24, 2003
    Inventors: Dennis Macejak, Patrice Lee
  • Hemofiltration systems, methods and devices used to treat inflammatory mediator related disease
    Publication number: 20010051106
    Abstract: A hemofiltration system for a mammal comprises a hemofilter and an adsorbent device. The hemofilter removes ultrafiltrate from a blood stream extracted from the mammal to create a filtered blood stream and an ultrafiltrate stream. The adsorbent device is comprised of one or more adsorbent materials and is used to adsorb inflammatory mediators from the ultrafiltrate stream received from the hemofilter removing inflammatory mediators that cause inflammatory mediator related disease, sepsis, and SIRS/MODS/MOSF to create a post adsorption ultrafiltrate stream. The post adsorption ultrafiltrate stream is selectively combined with the filtered blood stream and together with the filtered blood stream is returned to the mammal.
    Type: Application
    Filed: July 25, 2001
    Publication date: December 13, 2001
    Applicant: Immunocept, L.L.C.
    Inventors: James R. Matson, Patrice A. Lee
  • Hemofiltration of toxic mediator-related disease
    Patent number: 5571418
    Abstract: The present invention provides methods of treating pathophysiological states characterized by the presence in blood of certain toxic mediators. The novel method of hemofiltration of the present invention provides an effective treatment of several such disease including sepsis, shock, acute renal failure, multiple organ system failure and systemic inflammatory response syndrome-related diseases.
    Type: Grant
    Filed: July 6, 1994
    Date of Patent: November 5, 1996
    Inventors: Patrice A. Lee, James R. Matson, Robert W. Pryor